Actin-related protein 2/3 complex subunit 2

BE0004252ProteinHumansARPC2

Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). It is acted on by 3 drugs in DrugBank.

Gene name
ARPC2
UniProtKB entry
O15144Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
300 residues · 34,333 Da
Also known as
ARC34 · Arp2/3 complex 34 kDa subunit · p34-ARC

Resolves to

Protein
UniProtO15144UniProt nameARPC2_HUMAN
Gene
HGNCHGNC:705NCBI Gene10109GenBank2282036GeneCardsARPC2
Pharmacology
KEGGhsa:10109
Structure
PDB6UHCPDB6YW6PDB6YW7
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Actin-related protein 2/3 complex subunit 2, and which indications are they being tested in?

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