Actin-related protein 2/3 complex subunit 3

BE0004253ProteinHumansARPC3

Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). It is acted on by 2 drugs in DrugBank.

Gene name
ARPC3
UniProtKB entry
O15145Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
178 residues · 20,547 Da
Also known as
ARC21 · Arp2/3 complex 21 kDa subunit · p21-ARC

Resolves to

Protein
UniProtO15145UniProt nameARPC3_HUMAN
Gene
HGNCHGNC:706NCBI Gene10094GenBank2209347GeneCardsARPC3
Pharmacology
KEGGhsa:10094
Structure
PDB6UHCPDB6YW6PDB6YW7
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
12+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Actin-related protein 2/3 complex subunit 3, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In