Aminopeptidase N

BE0004334ProteinEscherichia coli (strain K12)pepN

Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation. It is acted on by 1 drug in DrugBank.

Gene name
pepN
UniProtKB entry
P04825Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
870 residues · 98,918 Da
Also known as
3.4.11.2 · Alpha-aminoacylpeptide hydrolase

Resolves to

Protein
UniProtP04825UniProt nameAMPN_ECOLI
Gene
NCBI Gene947253GenBank42353
Pharmacology
KEGGecj:JW0915
Structure
PDB2DQ6PDB2DQMPDB2HPO
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Aminopeptidase N, and which indications are they being tested in?

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