3-ketoacyl-CoA thiolase, peroxisomal

BE0004521ProteinHumansACAA1

Responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs) (PubMed:11734571, PubMed:2882519).

Gene name
ACAA1
UniProtKB entry
P09110Swiss-Prot
Cellular location
Peroxisome
Residues / weight
424 residues · 44,292 Da
Also known as
2.3.1.16 · ACAA · Acetyl-CoA acyltransferase · Acetyl-CoA C-myristoyltransferase · Beta-ketothiolase

Resolves to

Protein
UniProtP09110UniProt nameTHIK_HUMAN
Gene
HGNCHGNC:82NCBI Gene30GeneCardsACAA1
Pharmacology
KEGGhsa:30
Structure
PDB2IIKPDB9OK4

What you can answer from here — as of September 07, 2019

1Metabolic reactionDrug transformations it catalyses, substrate to product
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
9+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on 3-ketoacyl-CoA thiolase, peroxisomal, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In