Pterin-4-alpha-carbinolamine dehydratase

BE0004555ProteinHumansPCBD1

Involved in tetrahydrobiopterin biosynthesis (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
PCBD1
UniProtKB entry
P61457Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
104 residues · 12,000 Da
Also known as
4-alpha-hydroxy-tetrahydropterin dehydratase · 4.2.1.96 · DCOH · Dimerization cofactor of hepatocyte nuclear factor 1-alpha · Dimerization cofactor of HNF1

Resolves to

Protein
UniProtP61457UniProt namePHS_HUMAN
Gene
HGNCHGNC:8646NCBI Gene5092GeneCardsPCBD1
Pharmacology
KEGGhsa:5092
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Pterin-4-alpha-carbinolamine dehydratase, and which indications are they being tested in?

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