5-hydroxytryptamine receptor 5A

BE0004688ProteinHumansHTR5A

G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35610220, PubMed:35835867, PubMed:9865521). It is acted on by 8 drugs in DrugBank.

Gene name
HTR5A
UniProtKB entry
P47898Swiss-Prot
Cellular location
Cell membrane
Residues / weight
357 residues · 40,255 Da
Also known as
5-HT-5 · 5-HT-5A · 5-HT5A · Serotonin receptor 5A

Resolves to

Protein
UniProtP47898UniProt name5HT5A_HUMAN
Gene
HGNCHGNC:5300NCBI Gene3361GeneCardsHTR5A
Pharmacology
IUPHAR/GtoPdb10KEGGhsa:3361
Structure
PDB7UM4PDB7UM5PDB7UM6
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 5-hydroxytryptamine receptor 5A, how selective are they, and which programs against it are still in active trials?

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