Sodium/nucleoside cotransporter 2

BE0004781ProteinHumansSLC28A2

Sodium-dependent and purine-selective transporter (PubMed:10087507, PubMed:9435697). It is acted on by 4 drugs in DrugBank.

Gene name
SLC28A2
UniProtKB entry
O43868Swiss-Prot
Cellular location
Membrane
Residues / weight
658 residues · 71,926 Da
Also known as
CNT 2 · CNT2 · Concentrative nucleoside transporter 2 · hCNT2 · Na(+)/nucleoside cotransporter 2

Resolves to

Protein
UniProtO43868UniProt nameS28A2_HUMAN
Gene
HGNCHGNC:11002NCBI Gene9153GeneCardsSLC28A2
Pharmacology
IUPHAR/GtoPdb1115KEGGhsa:9153
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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21GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium/nucleoside cotransporter 2, how selective are they, and which programs against it are still in active trials?

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