Solute carrier family 2, facilitated glucose transporter member 9

BE0004783ProteinHumansSLC2A9

High-capacity urate transporter, which may play a role in the urate reabsorption by proximal tubules (PubMed:18327257, PubMed:18701466, PubMed:22647630, PubMed:28083649, PubMed:36749388). It is acted on by 7 drugs in DrugBank.

Gene name
SLC2A9
UniProtKB entry
Q9NRM0Swiss-Prot
Cellular location
Cell membrane
Residues / weight
540 residues · 58,701 Da
Also known as
Glucose transporter type 9 · GLUT-9 · GLUT9 · Urate transporter

Resolves to

Protein
UniProtQ9NRM0UniProt nameGTR9_HUMAN
Gene
HGNCHGNC:13446NCBI Gene56606GeneCardsSLC2A9
Pharmacology
KEGGhsa:56606
Structure
PDB8Y65PDB8Y66PDB8ZXM
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 2, facilitated glucose transporter member 9, how selective are they, and which programs against it are still in active trials?

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