Programmed cell death protein 6

BE0005812ProteinHumansPDCD6

Calcium sensor that plays a key role in processes such as endoplasmic reticulum (ER)-Golgi vesicular transport, endosomal biogenesis or membrane repair. It is acted on by 6 drugs in DrugBank.

Gene name
PDCD6
UniProtKB entry
O75340Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
191 residues · 21,868 Da
Also known as
ALG-2 · ALG2 · Apoptosis-linked gene 2 protein homolog

Resolves to

Protein
UniProtO75340UniProt namePDCD6_HUMAN
Gene
HGNCHGNC:8765NCBI Gene10016GeneCardsPDCD6
Pharmacology
KEGGhsa:10016
Structure
PDB2ZN8PDB2ZN9PDB2ZND
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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23GO termsFunction, process and component, as structured annotations
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Programmed cell death protein 6, how selective are they, and which programs against it are still in active trials?

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