Calcium and integrin-binding family member 2

BE0008698ProteinHumansCIB2

Calcium- and integrin-binding protein that plays a role in intracellular calcium homeostasis (By similarity). It is acted on by 3 drugs in DrugBank.

Gene name
CIB2
UniProtKB entry
O75838Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
187 residues · 21,643 Da
Also known as
Kinase-interacting protein 2 · KIP 2 · KIP2

Resolves to

Protein
UniProtO75838UniProt nameCIB2_HUMAN
Gene
HGNCHGNC:24579NCBI Gene10518GeneCardsCIB2
Pharmacology
KEGGhsa:10518
Structure
PDB8XOQ
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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17GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcium and integrin-binding family member 2, how selective are they, and which programs against it are still in active trials?

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