Tyrosine-protein kinase Tec

BE0009385ProteinHumansTEC

Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regulation of the actin cytoskeleton. It is acted on by 4 drugs in DrugBank.

Gene name
TEC
UniProtKB entry
P42680Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
631 residues · 73,581 Da
Also known as
2.7.10.2 · PSCTK4

Resolves to

Protein
UniProtP42680UniProt nameTEC_HUMAN
Gene
HGNCHGNC:11719NCBI Gene7006GeneCardsTEC
Pharmacology
IUPHAR/GtoPdb2238KEGGhsa:7006
Structure
PDB2LUL
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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12GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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24+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tyrosine-protein kinase Tec, how selective are they, and which programs against it are still in active trials?

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