Aquaporin-9

BE0010004ProteinHumansAQP9

Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:10564231, PubMed:30420639, PubMed:35054513, PubMed:9514918). It is acted on by 7 drugs in DrugBank.

Gene name
AQP9
UniProtKB entry
O43315Swiss-Prot
Cellular location
Cell membrane
Residues / weight
295 residues · 31,431 Da
Also known as
AQP-9 · Aquaglyceroporin-9 · Small solute channel 1 · SSC1

Resolves to

Protein
UniProtO43315UniProt nameAQP9_HUMAN
Gene
HGNCHGNC:643NCBI Gene366GeneCardsAQP9
Pharmacology
KEGGhsa:366
Drugs

What you can answer from here — as of May 27, 2020

7DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aquaporin-9, how selective are they, and which programs against it are still in active trials?

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