Enzyme Inhibitors

Name
Enzyme Inhibitors
Accession Number
DBCAT000003
Description

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Drugs
DrugDrug Description
LepirudinA protein-based direct thrombin inhibitor used to reverse and prevent thrombus formation in heparin-induced thrombocytopenia.
BivalirudinA direct thrombin inhibitor used to treat heparin-induced thrombocytopenia and to prevent thrombosis during percutaneous coronary intervention.
Alpha-1-proteinase inhibitorA purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency.
CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
PravastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
FluvoxamineA selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
RamiprilAn ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure.
MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
CarbidopaA dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms.
FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
PyrimethamineAn antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.
TiclopidineA platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
RemikirenFor the treatment of hypertension and heart failure
PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
MoxifloxacinA fluoroquinolone antibiotic used to treat various bacterial infections.
NelfinavirA viral protease inhibitor used in the treatment of HIV infection.
IndinavirA protease inhibitor used to treat HIV infection.
LovastatinAn HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
MilrinoneAn inotropic vasodilator agent used to treat acute, decompensated heart failure.
NevirapineA non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
IdoxuridineA pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
DapsoneA sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DicoumarolFor decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis.
TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
ArgatrobanA synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
AcarboseAn alpha-glucosidase inhibitor used in conjunction with diet and exercise for management of type II diabetes mellitus.
RaltitrexedA folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer.
MitomycinAn antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies.
EthoxzolamideFor use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
CapreomycinAn aminoglycoside antibiotic used as an adjunct drug in tuberculosis.
GefitinibA tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
TolcaponeA catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
PimecrolimusA topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons.
OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
NitisinoneA hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods.
AminoglutethimideAn adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome.
GrepafloxacinA fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.
DexrazoxaneA cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer.
TacrineFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
ValrubicinAn anthracycline used intravesically in the treatment of BCG-resistant bladder carcinoma.
SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
MupirocinAn antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes.
MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
AllopurinolA xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
CerivastatinA statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events.
TrimethoprimAn antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
GemcitabineA nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
TeniposideA cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
EpirubicinAn anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer.
ChloramphenicolA broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
KetorolacAn NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
EnoxacinFor the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria...
TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
RimantadineAn RNA synthesis inhibitor used to prevent influenza A infection.
CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
PefloxacinFor the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
FosinoprilAn ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
EntacaponeA selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease.
ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
TolmetinAn NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
AcetyldigitoxinUsed for fast digitalization in congestive heart failure.
TrandolaprilA prodrug of an ACE inhibitor used to treat hypertension, congestive heart failure, and to improve survival following a myocardial infarction.
FoscarnetAn antiviral used to treat CMV, HIV, and HSV infections.
ErlotinibAn EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
RofecoxibA COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
BenazeprilAn ACE inhibitor prodrug used to treat hypertension.
PyridostigmineA cholinesterase inhibitor used to treat myasthenia gravis.
Acetohydroxamic acidA synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract.
PentostatinAn adenosine deaminase inhibitor used to treat hairy cell leukemia.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
ZanamivirA neuraminidase inhibitor used to treat influenza A and B.
MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
VoriconazoleA triazole compound used to treat fungal infections.
EnalaprilA prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
LinezolidAn oxazolidinone antibiotic used to treat susceptible strains of multidrug resistant bacterial infections.
SulindacAn NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
FurazolidoneFor the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
CandoxatrilCandoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
SimvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
PemetrexedA folate analog used to treat mesothelioma and non-small cell lung cancer.
StavudineA dideoxynucleoside used in the treatment of HIV infection.
DyphyllineA theophylline derivative used to treat asthma, bronchospasm, and COPD.
GalantamineA cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.
IsoflurophateFor use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
TrovafloxacinAn antibiotic used to treat gonorrhea and chlamydia.
MoexiprilAn angiotensin converting enzyme inhibitor prodrug used to treat hypertension.
DaunorubicinAn anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
AmprenavirA protease inhibitor used to treat HIV infection.
MethazolamideA carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma.
DelavirdineA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
LamivudineA reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
DiethylcarbamazineAn anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa.
FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
Adefovir dipivoxilA nucleotide analog used to treat chronic hepatitis B.
LisinoprilAn ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction.
EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
ZileutonA leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
TranylcypromineA monoamine oxidase inhibitor used to treat major depressive disorder.
TetracyclineAn antibiotic used to treat a wide variety of susceptible infections.
IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
MetyrosineA tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma.
Clavulanic acidA beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
MalathionA parasympathomimetic organophosphate used to treat head lice.
EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
Nalidixic acidA quinolone antibiotic used to treat urinary tract infections.
PhenelzineA monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
MarimastatFor the treatment of various cancers
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
PerindoprilAn ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction.
GentamicinAn aminoglycoside used to treat a wide variety of infections in the body.
PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
AcetazolamideA carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
DisulfiramA carbamate derivative used to treat alcohol addiction.
CinoxacinFor the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and...
DonepezilAn acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia.
TerbinafineAn allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
DiflunisalAn NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
TacrolimusA calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
DorzolamideA carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
EmtricitabineA nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV.
QuinaprilAn ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease.
OmapatrilatFor the treatment of hypertension.
DidanosineA reverse transcriptase inhibitor used to treat HIV.
Etacrynic acidA diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
LevosimendanFor short term treatment of acutely decompensated severe chronic heart failure (CHF). Also being investigated for use/treatment in heart disease.
AzacitidineA pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
ZalcitabineA dideoxynucleoside used to treat HIV.
DemecariumFor the topical treatment of chronic open-angle glaucoma.
NetilmicinAn aminoglycoside used to treat a wide variety of infections in the body.
DactinomycinAn actinomycin used to treat a wide variety of cancers.
AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
DipyridamoleA phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
LomefloxacinA fluoroquinolone used to prevent and treat a wide variety of infections in the body.
PhysostigmineA cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity.
RivastigmineA cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's.
ExemestaneAn aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
DoxorubicinA medication used to treat various cancers and Kaposi's Sarcoma.
HydroxyureaAn antimetabolite used to treat sickle cell anemia crisis.
LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
EdrophoniumA cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis.
MetyraponeA steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
Mycophenolic acidAn immunosuppressant used to prevent organ transplant rejections.
KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
TopotecanAn antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
MercaptopurineAn antineoplastic agent used to treat acute lymphocytic leukemia.
SelegilineA monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
GatifloxacinA fourth generation fluoroquinolone used to treat a wide variety of infections in the body.
RifampicinAn antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis.
AbacavirAn antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
NovobiocinFor the treatment of infections due to staphylococci and other susceptible organisms
EchothiophateAn acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma.
NorfloxacinA broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.
AtazanavirAn antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
FludarabineA purine analog antimetabolite that inhibits DNA synthesis.
AtorvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DeslanosideFor the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
StreptomycinAn aminoglycoside antibiotic indicated to treat mycobacterium tuberculosis and various non-tuberculosis infections.
OrlistatA reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance.
OuabainFor the treatment of atrial fibrillation and flutter and heart failure
LeflunomideA pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
QuinacrineFor the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
TrilostaneUsed in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
PapaverineAn alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
AtovaquoneAn antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
AmiodaroneA class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
AmbenoniumA cholinesterase inhibitor that targets both muscarinic and nicotinic receptors indicated for the treatment of myasthenia gravis.
DutasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
LevofloxacinA fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.
DiclofenamideA carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.
DesipramineA tricyclic antidepressant used in the treatment of depression.
GemifloxacinA quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.
BupropionA norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
TrimetrexateA folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.
OfloxacinAn antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
MoclobemideA monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder.
KanamycinAn aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria.
OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
IdarubicinAn anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
ClindamycinA lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
BrinzolamideA carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
MitoxantroneA chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
RidogrelUsed as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction.
SparfloxacinFor the treatment of adults with the following infections caused by susceptible strains microorganisms: community-acquired pneumonia (caused by Chlamydia pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, or Streptococcus...
ClarithromycinA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
AnastrozoleA competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
SaquinavirAn HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
GemfibrozilA lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
IsocarboxazidA monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs.
DasatinibA tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
LapatinibAn antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments.
SitagliptinAn oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.
DecitabineA chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression.
PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
DarunavirA HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
TelbivudineA thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
FosamprenavirAn antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
CilazaprilAn ACE inhibitor used for the management of hypertension and heart failure.
SpiraprilSpirapril is an ACE inhibitor class drug used to treat hypertension.
RasagilineAn irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa.
MibefradilFor the treatment of angina and high blood pressure.
DigitoxinA cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
Magnesium salicylateAn NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
NeostigmineA cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone.
TemafloxacinFor the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
AmrinoneA positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.
CilastatinA renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
LopinavirAn HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
TazobactamA beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
HydroxychloroquineAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
PargylineFor the treatment of moderate to severe hypertension.
LincomycinAn antibiotic indicated only for the treatment of serious infections, and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate.
EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
GenisteinCurrently Genistein is being studied in clinical trials as a treatment for prostate cancer.
ChymostatinNot Available
N,N-dimethylarginineAsymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which...
PiclamilastPiclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as...
CastanospermineNot Available
7-HydroxystaurosporineNot Available
RolipramA phosphodiesterase inhibitor with antidepressant properties.
StaurosporineAn indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
AlrestatinNot Available
GabaculineNot Available
Aminooxyacetic acidA compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
3,5-DinitrocatecholNot Available
DaidzinNot Available
OlomoucineNot Available
K-252aNot Available
7-NitroindazoleNot Available
IlomastatNot Available
5'-S-methyl-5'-thioadenosineNot Available
1,10-PhenanthrolineNot Available
TolrestatFor the pharmacological control of certain diabetic complications.
GeldanamycinNot Available
Trehalose-6-PhosphateNot Available
VorinostatA histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
PhosphoramidonNot Available
4-HydroxyphenylglycineNot Available
LY-294002Specific inhibitor of phosphatidylinositol 3-kinase.
Fusidic acidA topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.
ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
KifunensineNot Available
PyrazoleNot Available
Phosphonoacetic AcidA simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]
N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-ProlineNot Available
Calyculin ANot Available
DazoxibenNot Available
3-MethoxybenzamideNot Available
BenzamidineNot Available
DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
ImidazoleNot Available
EnalkirenNot Available
UbenimexAn adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia.
Sparfosic acidSparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen...
AlvocidibInvestigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).
2-(4-Chlorophenyl)-5-QuinoxalinecarboxamideNot Available
EniluracilFor the treatment of cancer in combination with 5-fluorouracil.
PhencyclidineA hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like...
Picric acidUsed as antiseptic, astringent, and stimulant for epitheliazation.
RadicicolNot Available
Palmitic AcidA fatty used as a food additive and emollient or surfactant in cosmetics.
CilomilastInvestigated for use/treatment in chronic obstructive pulmonary disease (COPD).
BatimastatNot Available
S-HexylglutathioneNot Available
SparsomycinAn antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
NitroarginineAn inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in...
Dipicolinic acidNot Available
OxfenicineOxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Maleic AcidNot Available
D-4-hydroxyphenylglycineNot Available
3,4-DichloroisocoumarinNot Available
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideNot Available
2,4-DinitrophenolA toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman,...
GlyphosateNot Available
Niflumic acidUsed in the treatment of rheumatoid arthritis.
FleroxacinFleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
5-iodotubercidinNot Available
AllosamidinAllosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
MetoprineNot Available
CamptothecinInvestigated for the treatment of cancer.
NimesulideFor the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
LawsoneNot Available
BenoxaprofenThe use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets...
IproniazidFor the treatment of depression (originally intended to treat tuberculosis).
NialamideWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
CediranibFor the treatment of liver cancer, advanced non-small cell lung cancer (NSCLC), advanced colorectal cancer (CRC) and other solid tumors.
Huperzine AInvestigated for use/treatment in alzheimer's disease.
HalofuginoneFor the treatment of scleroderma, cancer, and restenosis.
VildagliptinA once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus.
VogliboseFor the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
VatalanibUsed in combination with first- and second-line chemotherapy for the treatment of metastatic colorectal cancer and non-small cell lung cancer (NSCLC).
EnoximoneFor the treatment of congestive heart failure.
XimelagatranFor the treatment of acute deep vein thrombosis.
StannsoporfinInvestigated for use/treatment in liver disease, metabolic disease, and pediatric indications.
PermethrinAn insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
RanpirnaseFor the treatment of various forms of cancer.
BelinostatA histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
AmonafideInvestigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
TetrathiomolybdateInvestigated for use/treatment in liver disease and pulmonary fibrosis.
PrinomastatInvestigated for use/treatment in brain cancer, lung cancer, and prostate cancer.
ElafinInvestigated for use/treatment in inflammatory disorders (unspecified).
PTC299Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
OxypurinolIntended for the treatment of congestive heart failure and hyperuricemia.
EcabetFor the treatment of reflux oesophagitis and peptic ulcer disease.
IbudilastFor the treatment of multiple sclerosis, asthma, and cerebrovascular disease.
DexlansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Varespladib methylInvestigated for use/treatment in atherosclerosis and coronary artery disease.
AbirateroneAn antiandrogen used in the treatment of prostate cancer.
RubitecanInvestigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified).
GarenoxacinInvestigated for use/treatment in bacterial infection.
PixantroneAn antineoplastic agent use to treat patients with relapsed or refractory aggressive Non-Hodgkin B-cell Lymphomas (NHL).
SeliciclibInvestigated for use/treatment in breast cancer, lung cancer, lymphoma (unspecified), multiple myeloma, leukemia (lymphoid), and cancer/tumors (unspecified).
AlogliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus.
RivaroxabanA factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
EflornithineA medication used topically to reduce unwanted facial hair growth in women. The postulated mechanism of action is through irreversible inhibition of ornithine decarboxylase (ODC) in the skin.
ExisulindInvestigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
UdenafilInvestigated for use/treatment in erectile dysfunction and hypertension.
SimeprevirA direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
DarapladibInvestigated for use/treatment in atherosclerosis.
SaxagliptinAn DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
IclaprimInvestigated for use/treatment in bacterial infection, skin infections/disorders, obesity, liver disease, kidney disease, and pneumonia.
IdraparinuxInvestigated for use/treatment in thrombosis, venous thromboembolism, strokes, heart disease, and atrial fibrillation.
EtravirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
TezacitabineInvestigated for use/treatment in colorectal cancer, lung cancer, leukemia (unspecified), and gastric cancer.
SemaxanibInvestigated for use/treatment in colorectal cancer and lung cancer.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
PanobinostatA non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
ApixabanAn anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.
PeramivirAn intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days.
AxitinibAn oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
N-chlorotaurineInvestigated for use/treatment in eye disorders/infections.
OtamixabanInvestigated for use/treatment in thrombosis.
AprotininA serine protease inhibitor used to reduce the risk for perioperative blood loss and the need for blood transfusion in high-risk patients during cardiopulmonary bypass for coronary artery bypass graft surgery.
MevastatinNot used therapeutically due to its many side effects.
Dabigatran etexilateAn anticoagulant used for the prevention of venous thromboembolic events or stroke in patients with recent elective hip or knee replacement surgery and atrial fibrillation.
IobenguaneA radiopharmaceutical agent used for the diagnosis of primary and metastatic pheochromocytoma or neuroblastoma.
beta-Naphthoflavoneβ-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
Bafilomycin A1The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins...
BesifloxacinA fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.
PlicamycinFor the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer.
RaltegravirAn antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals.
ViomycinViomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis.
VeliparibNot Available
4-(2-Aminoethyl)Benzenesulfonyl FluorideNot Available
Brefeldin AA metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
AnisomycinAnisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.
Z-Val-Ala-Asp fluoromethyl ketoneNon-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the...
3-isobutyl-1-methyl-7H-xanthineNot Available
5-(2-methylpiperazine-1-sulfonyl)isoquinolineNot Available
PuromycinPuromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
ParecoxibA selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolinePotent reversible inhibitor of phenylethanolamine N-methyltransferase.
ThiorphanA potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
TemocaprilTemocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction).
PitavastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
RilpivirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
AminopterinPrior to its withdrawal, aminopterin was initially used in the treatment of childhood leukemia; specifically to induce remissions. Later, aminopterin was used off-label in the United States to treat psoriasis,...
LinagliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
TofacitinibA Janus kinase (JAK) inhibitor used to treat rheumatoid and psoriatic arthritis, and ulcerative colitis. It is not recommended to be combined with biologic therapies or potent immunosuppressants like cyclosporine or azathioprine.
PonatinibA kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).
FormestaneFor the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
TrametinibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
DabrafenibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
DolutegravirAn antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.
IndoprofenA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
FlumequineFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
FenbufenFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
EliglustatA glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers, based on the FDA-approved test.
IdelalisibAn antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
AvibactamA non-β-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and hospital or ventilator-acquired pneumonia.
CeritinibAn antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.
CobicistatA CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
PalbociclibAn endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
OlaparibA chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.
EdoxabanA novel oral anticoagulant used for reducing the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF).
LenvatinibA receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
NintedanibA triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.
ChlortetracyclineThe first tetracycline antibiotic most commonly used for veterinary purposes.
Methylene blueAn oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
PirlindoleFor the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving...
ToloxatoneFor the treatment of major depressive disorder.
DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
TrapidilUsed in the treatment of chronic stable angina .
SulbactamAn beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
OsimertinibA tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
AlatrofloxacinA fluoroquinolone antibiotic used to treat a variety of bacterial infections.
MersalylElevated blood pressure, edema [L1577, L1585].
EnalaprilatAn antihypertensive agent used for the management of hypertension when oral therapy is not practical.
CoumaphosThis drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a...
DichlorvosDichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products...
FenthionFenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is...
MonensinMonensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
PimobendanNot Annotated
RotenoneRotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also...
MetrifonateMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
VirginiamycinVirginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent...
DeslorelinDeslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones.
Isatoic anhydrideNot Available
Antithrombin III humanAn alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency.
AclarubicinNot Annotated
CandoxatrilatA dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP,...
OpicaponeA catechol-O-methyltransferase inhibitor used to treat Parkinson's disease in patients currently receiving levodopa and a dopa decarboxylase inhibitor.
RebamipideRebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
CurcuminNo approved therapeutic indications.
RacecadotrilRacecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
TalazoparibA poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer.
PazufloxacinPazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).
ImidaprilImidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
MirodenafilMirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
NiraparibA poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.
SaracatinibSaracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer.
TilarginineTilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.
RuboxistaurinRuboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus.
MocetinostatMocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.
EntinostatEntinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic...
Acridine CarboxamideAcridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.
PrulifloxacinPrulifloxacin has been investigated for the treatment of Urinary Tract Infection.
VarespladibVarespladib has been investigated for the treatment and prevention of Sickle Cell Disease, Vaso-occlusive Crisis, and Acute Coronary Syndrome.
LanopepdenLanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial.
6-O-benzylguanine6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
SafingolSafingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
DelanzomibDelanzomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin.
LetaxabanLetaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.
OzagrelOzagrel has been used in trials studying the treatment of Dry Eye Syndromes.
UlinastatinUlinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to Drug.
OrantinibOrantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others.
VesnarinoneVesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
VinpocetineVinpocetine has been investigated for the treatment of Epilepsy.
GSK-256066Gsk256066 has been used in trials studying the treatment and diagnostic of SAR, Asthma, Mild Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis, among others.
S-3304S-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non...
ExatecanExatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
AtamestaneAtamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent.
AtevirdineAtevirdine has been used in trials studying the treatment of HIV Infections.
SimendanSimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
DarexabanDarexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
CantharidinThe only therapeutic use for which cantharidin is currently primarily indicated for is as an active ingredient in topical agents for treating common warts (verruca vulgaris), periungual warts, plantar warts,...
RucaparibAn anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.
RelebactamA beta-lactamase inhibitor used to prevent hydrolysis of beta-lactam antibiotics, leading to increased effectiveness.
R-306465R306465 has been used in trials studying the treatment of Neoplasms.
NitroaspirinNitroaspirin has been investigated for the treatment of Intermittent Claudication.
NadifloxacinNadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
TempolTempol has been used in trials studying the treatment of Anal Cancer.
BelotecanBelotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
LobucavirLobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
OltiprazOltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
IndobufenIndobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.
AbexinostatAbexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase...
PiperineBioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
NafamostatUsed as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement...
SisomicinSisomicin has been used in trials studying the treatment of Pyoderma.
MizoribineMizoribine has been investigated for the treatment of Rheumatoid Arthritis.
ApocyninAcetovanillone has been used in trials studying the treatment of Bronchial Asthma and Chronic Obstructive Pulmonary Disease.
SalirasibSalirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
Phenethyl IsothiocyanatePhenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders.
NB-001NB-001 has been investigated for the treatment of Recurrent Herpes Labialis.
N-omega-nitro-L-arginine methyl esterL-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
AtreleutonAtreleuton has been used in trials studying the treatment of Atherosclerosis and Coronary Artery Disease.
LometrexolLometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
BenserazideA medication used to treat Parkinson's disease, parkinsonism, and restless leg syndrome.
GabexateNo approved indication.
SivelestatSivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
Buthionine SulfoximineButhionine Sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
NolatrexedNolatrexed is under investigation in clinical trial NCT00012324 (Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer).
Nikkomycin ZNikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis.
DidoxDidox has been used in trials studying the supportive care of Gastric Cancer.
MitoguazoneMitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin.
HypericinHypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
MK-0873MK-0873 has been used in trials studying the treatment of Rheumatoid Arthritis.
Methanesulfonyl FluorideMethanesulfonyl Fluoride has been used in trials studying the treatment of Safety.
LiarozoleLiarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
TalarozoleTalarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
ZofenoprilZofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
RheinNo approved indication.
DaidzeinNot Annotated
SitafloxacinNot Annotated
ProscillaridinProscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,...
DelaprilNot Annotated
FlurithromycinNot Annotated
EmetineNot Annotated
LinsidomineNot Annotated
MetildigoxinNot Annotated
TenidapNot Annotated
ParaoxonNot Annotated
MelagatranNot Annotated
Oxolinic acidNot Annotated
ProquazoneNot Annotated
DistigmineDistigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to DB00545 and DB01400. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase...
CamostatA serine protease indicated in Japan to treat chronic pancreatitis.
DexrabeprazoleNot Annotated
VorozoleNot Annotated
RufloxacinRufloxacin is a quinolone antibiotic.
BrodimoprimNot Annotated
Calcium levulinateThis new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and...
AdefovirNot Annotated
HarmalineNot Annotated
BrofaromineNot Annotated
IniparibNot Annotated
Coumermycin A1Not Annotated
ClinafloxacinClinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of...
FurafyllineFurafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline.
ABT-341ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different).
WortmanninWortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
BasifunginBasifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , .
SC-236SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
NS-398NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.
Concanamycin AConcanamycin A is an H+-ATPase (vacuolar) inhibitor.
BenazeprilatNot Annotated
TenofovirTenofovir has been shown to be effective against HIV, herpes simplex virus-2, and hepatitis B virus. To know more about the specific product indications, please visit the information in the...
FosinoprilatFosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
RamiprilatThe active metabolite of the prodrug Ramipril.
PerindoprilatThe active metabolite of the prodrug Perindopril.
QuinaprilatThe active metabolite of the prodrug quinapril.
Lithium carbonateA medication used to treat manic episodes of bipolar disorder.
Magnesium levulinateNot Available
AcifluorfenAcifluorfen is a protoporphyrinogen oxidase inhibitor.
acetylleucyl-leucyl-norleucinalNot Available
Cholesterol sulfateComponent of human seminal plasma & spermatozoa.
ZenarestatInvestigated for use/treatment in neuropathy (diabetic).
S-EthylisothioureaS-Ethylisothiourea is a nitric oxide synthase inhibitor.
Oseltamivir acidNot Available
ZardaverineNot Available
IsoliquiritigeninIsoliquiritigenin is a precursor to several flavonones in many plants.
BrequinarNot Available
PiritreximPiritrexim has been used in trials studying the treatment of Bladder Cancer, Urethral Cancer, and Transitional Cell Cancer of the Renal Pelvis and Ureter.
ClorgilineAn antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
MeglutolAn antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as...
PimagedineInvestigated for use/treatment in diabetic kidney disease.
7-ethyl-10-hydroxycamptothecinInvestigated for use/treatment in colorectal cancer.
EmodinEmodin has been investigated for the treatment of Polycystic Kidney.
FasudilFasudil has been investigated in Carotid Stenosis.
EmivirineEmivirine has been used in trials studying the treatment of HIV Infections.
LapachoneLapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell.
EbselenEbselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.
DabigatranNot Annotated
Methoxy arachidonyl fluorophosphonateMethoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid...
CycloguanilCycloguanil is the active metabolite of proguanil.
Salvianolic acid ASalvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).
AntipainAntipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes. Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells...
Perillyl alcoholPerillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma).
EpalrestatEpalrestat is under investigation in clinical trial NCT03244358 (Evaluation of Epalrestat in Metastatic Triple-negative Breast Cancer).
CidofovirAn antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
FamciclovirA nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster.
CaspofunginAn echinocandin used to treat a variety of fungal infections.
TigecyclineA glycylcycline antibiotic used to treat a number of susceptible bacterial infections.
FondaparinuxAn anticoagulant used to prevent venous thromboembolism, to treat deep vein thrombosis, and to improve survival following myocardial infarction.
OxaprozinAn NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
FomepizoleAn inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
SunitinibA receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
TopiroxostatIndicated for the treatment of gout and hyperurcemia in Japan.
D-EritadenineNot Available
MonastrolNot Available
2,5-di-tert-butylhydroquinoneNot Available
LicofeloneFor the management of osteoarthritis.
MyxothiazolNot Available
Omacetaxine mepesuccinateA cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors.
PhenserineFor the treatment of Alzheimer's disease (AD).
RupintrivirInvestigated for use/treatment in viral infection.
RanirestatInvestigated for use/treatment in neuropathy (diabetic).
PelitinibInvestigated for use/treatment in colorectal cancer and lung cancer.
MotesanibInvestigated for use/treatment in solid tumors.
ArylacenamideInvestigated for use/treatment in cancer/tumors (unspecified), immunosuppressive, and prostate cancer.
AV-412Investigated for use/treatment in cancer/tumors (unspecified).
ElvucitabineInvestigated for use/treatment in hepatitis (viral, B) and HIV infection.
IndisulamInvestigated for use/treatment in lung cancer.
Human C1-esterase inhibitorA C1 inhibitor used to prevent angioedema attacks associated with hereditary angioedema.
LonafarnibA potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies.
CetilistatInvestigated for use/treatment in obesity.
MafenideAn antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.
CapravirineInvestigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
VemurafenibA kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
AfatinibAn antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy.
FinafloxacinFinafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1...
DesirudinIndicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery.
AsunaprevirAsunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis....
IlorasertibIlorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
PeficitinibPeficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
MK-1775MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.
PevonedistatPevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
MomelotinibMomelotinib has been used in trials studying the treatment of Polycythemia Vera, Primary Myelofibrosis, Post-Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis (PMF), among others.
PF-04991532PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders.
TosedostatTosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the...
GSK-2636771GSK2636771 has been used in trials studying the treatment of CANCER, LYMPHOMA, Solid Neoplasm, Recurrent Solid Neoplasm, and Advanced Malignant Neoplasm, among others.
PritelivirPritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
BafetinibBafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.
GedatolisibGedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer, Breast Cancer, Advanced Cancer, and Endometrial Cancer, among others.
FlumatinibFlumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic.
Bempedoic acidA drug used in conjunction with lifestyle modification and/or other agents for the treatment of refractory hypercholesterolemia.
TesevatinibTesevatinib has been used in trials studying the treatment of Cancer, Stomach Cancer, Brain Metastases, Esophageal Cancer, and Leptomeningeal Metastases, among others. Tesevatinib is a potent inhibitor of multiple RTKs...
EntrectinibEntrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment...
NaquotinibNaquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth Factor Receptor...
VaborbactamA beta lactamase inhibitor used to treat complicated urinary tract infections.
RigosertibRigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
ObatoclaxObatoclax has been used in trials studying the treatment of AML, Leukemia, Myelofibrosis, Hodgkin's Lymphoma, and Mantle-Cell Lymphoma, among others.
BetrixabanA Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients.
RicolinostatRicolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
ZamicastatZamicastat has been used in trials studying the treatment of Hypertension and Chronic Heart Failure.
GaleteroneGaleterone has been used in trials studying the treatment of Prostate Cancer.
AnagliptinAnagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.
DexelvucitabineDexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.
AcotiamideAcotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.
WNT-974WNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
RimacalibRimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).
BindaritBindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy.
RebastinibRebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.
LCB01-0371Lcb01 0371 is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
AZD-0424AZD0424 has been used in trials studying the treatment of Advanced Solid Tumours.
X-396X-396 has been used in trials studying the treatment of Advanced Solid Tumors and Non-small Cell Lung Cancer.
ReposalReposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia.
Baloxavir marboxilA polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.
IvosidenibAn isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation.
CPI-1205Potent and selective histone methyltransferase EZH2 inhibitor.
RivoceranibRivoceranib is under investigation in clinical trial NCT02726854 (Apatinib as Second-line Treatment of Advanced Pancreatic Cancer).
EnsartinibEnsartinib is under investigation in clinical trial NCT03420508 (Treating Patients With Melanoma and ALK Alterations With Ensartinib).
SelitrectinibSelitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers).
ImetelstatImetelstat is under investigation in clinical trial NCT01916187 (Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma).
SerabelisibSerabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics of TAK-117 (MLN1117)...
Etirinotecan pegolEtirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).
LinrodostatLinrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants).
PF-06700841PF-06700841 is under investigation in clinical trial NCT03236493 (Safety and Pharmacokinetic Study of PF-06700841 in Japanese Healthy Volunteers).
ZanubrutinibA kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy.
UpadacitinibAn oral Janus kinase (JAK)1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis in adult patients who did not respond well to methotrexate.
VoruciclibVoruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies or AML).
GDC-0084GDC-0084 is under investigation in clinical trial NCT03696355 (Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas).
KRN-5500KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).
AvidinAvidin is under investigation in clinical trial NCT00345618 (Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach).
CB-1158CB-1158 is under investigation in clinical trial NCT03910530 (A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors).
PosiphenPosiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
AbivertinibAbivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in...
CilazaprilatNot Annotated
p-Hydroxymercuribenzoic acidNot Available
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamideNot Available
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamideNot Available
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideNot Available
2-deoxy-2,3-dehydro-N-acetylneuraminic acidNot Available
ThiocitrullineNot Available
EchinomycinEchinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis.
Ursolic acidNot Annotated
N(G)-IminoethylornithineNot Available
R-82913Not Available
H-89Not Available
ZopolrestatNot Available
CGS-27023Not Available
Bisindolylmaleimide VIIINot Available
CP-320626Not Available
Trichostatin ANot Available
GW-813893Not Available
Y-27632Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.
Bisindolylmaleimide INot Available
5-BenzylacyclouridineNot Available
HarmineNot Available
DichlororibofuranosylbenzimidazoleNot Available
DorsomorphinNot Available
Adenosine 5'-methylenediphosphateNot Available
t-ButylhydroquinoneNot Available
IslatravirIslatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
MethyldopaAn alpha-2 adrenergic agonist used to treat hypertension.
BaloxavirBaloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).
(Rp)-cAMPSNot Available
VigabatrinAn irreversible GABA transaminase inhibitor used as an adjunct therapy to treat refractory complex partial seizures in patients ≥2 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years.
Zinc protoporphyrinNot Available
CarbarylNot Annotated
Drugs & Drug Targets
DrugTargetType
LepirudinProthrombintarget
BivalirudinProthrombintarget
BivalirudinMyeloperoxidaseenzyme
Alpha-1-proteinase inhibitorNeutrophil elastasetarget
CyclosporineCalcium signal-modulating cyclophilin ligandtarget
CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
CyclosporineCalcineurin subunit B type 2target
CyclosporineCytochrome P450 3A5enzyme
CyclosporineCytochrome P450 3A4enzyme
CyclosporineP-glycoprotein 1transporter
CyclosporineBile salt export pumptransporter
CyclosporineIleal sodium/bile acid cotransportertransporter
CyclosporineSodium/bile acid cotransportertransporter
CyclosporineSolute carrier family 22 member 6transporter
CyclosporineMultidrug resistance-associated protein 7transporter
CyclosporineCanalicular multispecific organic anion transporter 1transporter
CyclosporineATP-binding cassette sub-family G member 2transporter
CyclosporineSolute carrier organic anion transporter family member 1B1transporter
CyclosporineCytochrome P450 2C19enzyme
CyclosporineCytochrome P450 2D6enzyme
CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
CyclosporineSolute carrier organic anion transporter family member 1B3transporter
Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PravastatinSolute carrier organic anion transporter family member 2B1transporter
PravastatinP-glycoprotein 1transporter
PravastatinSolute carrier organic anion transporter family member 1A2transporter
PravastatinSolute carrier family 22 member 6transporter
PravastatinSolute carrier family 22 member 8transporter
PravastatinCanalicular multispecific organic anion transporter 1transporter
PravastatinSolute carrier family 22 member 11transporter
PravastatinATP-binding cassette sub-family G member 2transporter
PravastatinSolute carrier family 22 member 7transporter
PravastatinSolute carrier organic anion transporter family member 1B1transporter
PravastatinMonocarboxylate transporter 1transporter
PravastatinBile salt export pumptransporter
PravastatinSolute carrier organic anion transporter family member 1B3transporter
PravastatinHistone deacetylase 2target
FluvoxamineSodium-dependent serotonin transportertarget
FluvoxamineCytochrome P450 1A2enzyme
FluvoxamineCytochrome P450 2D6enzyme
FluvoxamineCytochrome P450 2C9enzyme
FluvoxamineCytochrome P450 2C19enzyme
FluvoxamineCytochrome P450 1A1enzyme
FluvoxamineCytochrome P450 3A4enzyme
FluvoxamineCytochrome P450 3A Subfamilyenzyme
FluvoxamineP-glycoprotein 1transporter
FluvoxamineCytochrome P450 2B6enzyme
FluvoxaminePotassium voltage-gated channel subfamily H member 2target
FluvoxamineBile salt export pumptransporter
RamiprilAngiotensin-converting enzymetarget
RamiprilSolute carrier family 15 member 1transporter
RamiprilSolute carrier family 15 member 2transporter
RamiprilCholinesteraseenzyme
RamiprilB1 bradykinin receptortarget
MasoprocolArachidonate 5-lipoxygenasetarget
MasoprocolArachidonate 5-lipoxygenaseenzyme
MasoprocolSex hormone-binding globulintarget
CarbidopaAromatic-L-amino-acid decarboxylasetarget
FluconazoleCytochrome P450 3A4enzyme
FluconazoleCytochrome P450 2C9enzyme
FluconazoleCytochrome P450 2C19enzyme
FluconazoleP-glycoprotein 1transporter
FluconazoleCytochrome P450 51target
FluconazoleCytochrome P450 3A5enzyme
Erythromycin23S ribosomal RNAtarget
ErythromycinCytochrome P450 3A4enzyme
ErythromycinCytochrome P450 3A7enzyme
ErythromycinP-glycoprotein 1transporter
ErythromycinSolute carrier organic anion transporter family member 1B1transporter
ErythromycinMotilin receptortarget
ErythromycinPotassium voltage-gated channel subfamily H member 2target
ErythromycinCytochrome P450 3A5enzyme
ErythromycinSolute carrier organic anion transporter family member 1B3transporter
ErythromycinBile salt export pumptransporter
ErythromycinCanalicular multispecific organic anion transporter 1transporter
ErythromycinSolute carrier organic anion transporter family member 1A2transporter
CaffeineAdenosine receptor A1target
CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
CaffeineAdenosine receptor A2atarget
CaffeineCytochrome P450 1A2enzyme
CaffeineRyanodine receptor 1target
CaffeineCytochrome P450 3A4enzyme
CaffeineCytochrome P450 2E1enzyme
CaffeineCytochrome P450 2C8enzyme
CaffeineCytochrome P450 2C9enzyme
CaffeineCytochrome P450 1A1enzyme
CaffeineCytochrome P450 1B1enzyme
CaffeineCytochrome P450 2D6enzyme
CaffeineCyclic nucleotide phosphodiesterasetarget
CaffeineDNA-dependent protein kinase catalytic subunittarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
CaffeineInositol 1,4,5-trisphosphate receptortarget
CaffeineSerine-protein kinase ATMtarget
CaffeineATP-binding cassette sub-family G member 2transporter
CaffeineAdenosine receptor A2btarget
CaffeineAdenosine receptor A3target
CaffeinePhosphodiesterase enzymestarget
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilMultidrug resistance-associated protein 4transporter
SildenafilMultidrug resistance-associated protein 5transporter
SildenafilMultidrug resistance-associated protein 7transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilP-glycoprotein 1transporter
PyrimethamineBifunctional dihydrofolate reductase-thymidylate synthasetarget
PyrimethamineDihydrofolate reductasetarget
PyrimethamineCytochrome P450 2C8enzyme
PyrimethamineBeta-hexosaminidase subunit betatarget
PyrimethamineMultidrug and toxin extrusion protein 1transporter
PyrimethamineMultidrug and toxin extrusion protein 2transporter
TiclopidineP2Y purinoceptor 12target
TiclopidineCytochrome P450 2C19enzyme
TiclopidineCytochrome P450 2B6enzyme
TiclopidineCytochrome P450 2C9enzyme
TiclopidineCytochrome P450 2D6enzyme
TiclopidineMyeloperoxidaseenzyme
TiclopidineCytochrome P450 1A2enzyme
TiclopidineCytochrome P450 2C8enzyme
TiclopidineCytochrome P450 2E1enzyme
RemikirenRenintarget
PantoprazolePotassium-transporting ATPase alpha chain 1target
PantoprazoleCytochrome P450 2C19enzyme
PantoprazoleCytochrome P450 3A4enzyme
PantoprazoleP-glycoprotein 1transporter
PantoprazoleATP-binding cassette sub-family G member 2transporter
PantoprazoleSolute carrier family 22 member 8transporter
PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
MoxifloxacinDNA gyrase subunit Atarget
MoxifloxacinDNA topoisomerase 4 subunit Atarget
MoxifloxacinDNA topoisomerase 2-alphatarget
MoxifloxacinCytochrome P450 1A2enzyme
NelfinavirHIV-1 proteasetarget
NelfinavirCytochrome P450 2C19enzyme
NelfinavirCytochrome P450 3A4enzyme
NelfinavirCytochrome P450 2B6enzyme
NelfinavirCytochrome P450 3A5enzyme
NelfinavirCytochrome P450 3A7enzyme
NelfinavirP-glycoprotein 1transporter
NelfinavirSolute carrier family 22 member 1transporter
NelfinavirSolute carrier organic anion transporter family member 1A2transporter
NelfinavirATP-binding cassette sub-family G member 2transporter
NelfinavirSolute carrier organic anion transporter family member 1B1transporter
NelfinavirCytochrome P450 2D6enzyme
NelfinavirSerum albumincarrier
NelfinavirUDP-glucuronosyltransferase 1-1enzyme
NelfinavirSolute carrier organic anion transporter family member 1B3transporter
NelfinavirSolute carrier organic anion transporter family member 2B1transporter
NelfinavirBile salt export pumptransporter
NelfinavirCytochrome P450 2C9enzyme
IndinavirHuman immunodeficiency virus type 1 proteasetarget
IndinavirCytochrome P450 3A4enzyme
IndinavirCytochrome P450 3A5enzyme
IndinavirCytochrome P450 3A7enzyme
IndinavirP-glycoprotein 1transporter
IndinavirSolute carrier family 22 member 1transporter
IndinavirMultidrug resistance-associated protein 1transporter
IndinavirSolute carrier organic anion transporter family member 1A2transporter
IndinavirSolute carrier organic anion transporter family member 1B1transporter
IndinavirCanalicular multispecific organic anion transporter 1transporter
IndinavirCytochrome P450 2D6enzyme
IndinavirUDP-glucuronosyltransferase 1-1enzyme
IndinavirSolute carrier organic anion transporter family member 2B1transporter
IndinavirBile salt export pumptransporter
Lovastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
LovastatinCytochrome P450 3A4enzyme
LovastatinCytochrome P450 2C8enzyme
LovastatinIntegrin alpha-Ltarget
LovastatinHistone deacetylase 2target
LovastatinSerum paraoxonase/lactonase 3enzyme
LovastatinP-glycoprotein 1transporter
LovastatinSolute carrier organic anion transporter family member 1A2transporter
LovastatinSolute carrier organic anion transporter family member 1B1transporter
LovastatinUDP-glucuronosyltransferase 1-1enzyme
LovastatinUDP-glucuronosyltransferase 1-3enzyme
LovastatinUDP-glucuronosyltransferase 2B7enzyme
LovastatinCanalicular multispecific organic anion transporter 1transporter
LovastatinBile salt export pumptransporter
LovastatinSerum albumincarrier
LovastatinCytochrome P450 2C19enzyme
LovastatinSolute carrier organic anion transporter family member 2B1transporter
LovastatinSolute carrier organic anion transporter family member 1B3transporter
MilrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
NevirapineCytochrome P450 3A4enzyme
NevirapineCytochrome P450 2B6enzyme
NevirapineCytochrome P450 3A5enzyme
NevirapineCytochrome P450 2C9enzyme
NevirapineCytochrome P450 2A6enzyme
NevirapineCytochrome P450 2D6enzyme
NevirapineReverse transcriptase/RNaseHtarget
NevirapineSerum albumincarrier
NevirapineCytochrome P450 1A2enzyme
NevirapineSolute carrier family 22 member 1transporter
NevirapineCytochrome P450 3A7enzyme
IdoxuridineThymidine kinasetarget
IdoxuridineDNAtarget
DapsoneInactive dihydropteroate synthase 2target
DapsoneDihydropteroate synthase 1target
DapsoneCytochrome P450 2C9enzyme
DapsoneCytochrome P450 2E1enzyme
DapsoneCytochrome P450 3A4enzyme
DapsoneDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DapsoneProstaglandin G/H synthase 1enzyme
DapsoneProstaglandin G/H synthase 2enzyme
DapsoneCytochrome P450 2C8enzyme
DapsoneCytochrome P450 2C19enzyme
DapsoneArylamine N-acetyltransferase 2enzyme
DapsoneCytochrome P450 3A5enzyme
DapsoneCytochrome P450 3A7enzyme
DapsoneMyeloperoxidaseenzyme
DapsoneCytochrome P450 2C18enzyme
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
ClotrimazoleErgosteroltarget
DicoumarolVitamin K epoxide reductase complex subunit 1target
DicoumarolNAD(P)H dehydrogenase [quinone] 1target
DicoumarolQuinone oxidoreductasetarget
DicoumarolCytochrome P450 2C9enzyme
DicoumarolSerum albumincarrier
DicoumarolCytochrome P450 2C6enzyme
DicoumarolCytochrome P450 2C11enzyme
TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TheophyllineAdenosine receptor A2btarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
TheophyllineAdenosine receptor A1target
TheophyllineAdenosine receptor A2atarget
TheophyllineCytochrome P450 1A2enzyme
TheophyllineAdenosine deaminaseenzyme
TheophyllineCytochrome P450 2E1enzyme
TheophyllineCytochrome P450 3A4enzyme
TheophyllineSolute carrier family 22 member 7transporter
TheophyllineCytochrome P450 1A1enzyme
TheophyllineCytochrome P450 1B1enzyme
TheophyllineCytochrome P450 2D6enzyme
TheophyllineHistone deacetylase 2target
TheophyllineCopine-1target
TheophyllineMinor histocompatibility antigen H13target
TheophyllineNodal modulator 1target
TheophyllinePoly [ADP-ribose] polymerase 1target
TheophyllineProtein RIC-3target
TheophyllineTubulin monoglycylase TTLL3target
ArgatrobanProthrombintarget
ArgatrobanCytochrome P450 3A4enzyme
ArgatrobanCytochrome P450 3A5enzyme
ArgatrobanSerum albumincarrier
Argatrobanalpha1-acid glycoproteincarrier
AcarboseMaltase-glucoamylase, intestinaltarget
AcarboseLysosomal alpha-glucosidasetarget
AcarboseSucrase-isomaltase, intestinaltarget
AcarbosePancreatic alpha-amylasetarget
RaltitrexedThymidylate synthasetarget
RaltitrexedFolylpolyglutamate synthase, mitochondrialtarget
MitomycinDNAtarget
MitomycinNADPH--cytochrome P450 reductaseenzyme
EthoxzolamideCarbonic anhydrase 1target
EthoxzolamideSolute carrier family 22 member 6transporter
EthoxzolamideCarbonic anhydrase 2target
EthoxzolamideCarbonic anhydrase 4target
EthoxzolamideCarbonic anhydrase 7target
EthoxzolamideCarbonic anhydrase 3target
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
Capreomycin16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyAtarget
GefitinibEpidermal growth factor receptortarget
GefitinibCytochrome P450 3A4enzyme
GefitinibCytochrome P450 2D6enzyme
GefitinibP-glycoprotein 1transporter
GefitinibATP-binding cassette sub-family G member 2transporter
GefitinibCytochrome P450 3A5enzyme
GefitinibCytochrome P450 1A1enzyme
GefitinibCytochrome P450 2C9enzyme
GefitinibCytochrome P450 2C19enzyme
GefitinibSerum albumincarrier
GefitinibAlpha-1-acid glycoprotein 1carrier
TolcaponeCatechol O-methyltransferasetarget
TolcaponeCytochrome P450 2C9enzyme
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
PimecrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
PimecrolimusSerine/threonine-protein kinase mTORtarget
PimecrolimusCytochrome P450 3A4enzyme
OmeprazolePotassium-transporting ATPase alpha chain 1target
OmeprazoleCytochrome P450 2C19enzyme
OmeprazoleCytochrome P450 3A4enzyme
OmeprazoleCytochrome P450 2C9enzyme
OmeprazoleCytochrome P450 1A2enzyme
OmeprazoleCanalicular multispecific organic anion transporter 2transporter
OmeprazoleP-glycoprotein 1transporter
OmeprazoleATP-binding cassette sub-family G member 2transporter
OmeprazoleCytochrome P450 1A1enzyme
OmeprazoleCytochrome P450 1B1enzyme
OmeprazoleCytochrome P450 2C18enzyme
OmeprazoleCytochrome P450 2C8enzyme
OmeprazoleCytochrome P450 2D6enzyme
OmeprazoleAryl hydrocarbon receptortarget
Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
AminoglutethimideCytochrome P450 19A1target
AminoglutethimideCytochrome P450 2C19enzyme
AminoglutethimideCytochrome P450 3A4enzyme
AminoglutethimideCholesterol side-chain cleavage enzyme, mitochondrialtarget
GrepafloxacinDNA gyrase subunit Atarget
GrepafloxacinDNA topoisomerase 4 subunit Atarget
GrepafloxacinCytochrome P450 3A4enzyme
GrepafloxacinCytochrome P450 1A2enzyme
GrepafloxacinSolute carrier family 22 member 2transporter
GrepafloxacinSolute carrier family 22 member 5transporter
GrepafloxacinCanalicular multispecific organic anion transporter 1transporter
GrepafloxacinP-glycoprotein 1transporter
GrepafloxacinMultidrug resistance-associated protein 1transporter
GrepafloxacinSolute carrier family 22 member 6transporter
DexrazoxaneDNA topoisomerase 2-alphatarget
DexrazoxaneDNA topoisomerase 2-betatarget
TacrineAcetylcholinesterasetarget
TacrineCytochrome P450 1A2enzyme
TacrineCholinesterasetarget
TacrineP-glycoprotein 1transporter
TacrineLiver carboxylesterase 1target
ValrubicinDNA topoisomerase 2-alphatarget
ValrubicinDNAtarget
SorafenibSerine/threonine-protein kinase B-raftarget
SorafenibReceptor-type tyrosine-protein kinase FLT3target
SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
SorafenibVascular endothelial growth factor receptor 3target
SorafenibPlatelet-derived growth factor receptor betatarget
SorafenibMast/stem cell growth factor receptor Kittarget
SorafenibVascular endothelial growth factor receptor 2target
SorafenibCytochrome P450 3A4enzyme
SorafenibUDP-glucuronosyltransferase 1-9enzyme
SorafenibCytochrome P450 2B6enzyme
SorafenibCytochrome P450 2C8enzyme
SorafenibCytochrome P450 3A5enzyme
SorafenibCytochrome P450 3A7enzyme
SorafenibCytochrome P450 2C9enzyme
SorafenibMultidrug resistance-associated protein 4transporter
SorafenibP-glycoprotein 1transporter
SorafenibCanalicular multispecific organic anion transporter 1transporter
SorafenibATP-binding cassette sub-family G member 2transporter
SorafenibCytochrome P450 1A2enzyme
SorafenibCytochrome P450 2C19enzyme
SorafenibCytochrome P450 2D6enzyme
SorafenibUDP-glucuronosyltransferase 1-1enzyme
SorafenibRalA-binding protein 1transporter
SorafenibFibroblast growth factor receptor 1target
SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
SorafenibVascular endothelial growth factor receptor 1target
SorafenibSolute carrier organic anion transporter family member 1B1transporter
MupirocinIsoleucine--tRNA ligasetarget
MiglustatCeramide glucosyltransferasetarget
AllopurinolXanthine dehydrogenase/oxidasetarget
AllopurinolSolute carrier family 22 member 8transporter
AllopurinolSolute carrier family 22 member 7transporter
AllopurinolAldehyde oxidaseenzyme
AllopurinolXanthine dehydrogenase/oxidaseenzyme
AllopurinolATP-binding cassette sub-family G member 2transporter
AllopurinolSolute carrier family 22 member 2transporter
Cerivastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
CerivastatinCytochrome P450 2C8enzyme
CerivastatinCytochrome P450 3A4enzyme
CerivastatinCytochrome P450 2D6enzyme
CerivastatinCytochrome P450 2C9enzyme
CerivastatinCytochrome P450 3A5enzyme
CerivastatinCytochrome P450 3A7enzyme
CerivastatinP-glycoprotein 1transporter
CerivastatinCanalicular multispecific organic anion transporter 1transporter
CerivastatinATP-binding cassette sub-family G member 2transporter
CerivastatinSolute carrier organic anion transporter family member 1B1transporter
CerivastatinCytochrome P450 2B6enzyme
CerivastatinUDP-glucuronosyltransferase 1-1enzyme
CerivastatinBile salt export pumptransporter
TrimethoprimDihydrofolate reductasetarget
TrimethoprimCytochrome P450 2C8enzyme
TrimethoprimCytochrome P450 3A4enzyme
TrimethoprimP-glycoprotein 1transporter
TrimethoprimCytochrome P450 2C9enzyme
TrimethoprimCytochrome P450 1A2enzyme
TrimethoprimMultidrug and toxin extrusion protein 1transporter
TrimethoprimMultidrug and toxin extrusion protein 2transporter
GemcitabineRibonucleoside-diphosphate reductase large subunittarget
GemcitabineUMP-CMP kinasetarget
GemcitabineThymidylate synthasetarget
GemcitabineCytidine deaminaseenzyme
GemcitabineDeoxycytidine kinaseenzyme
GemcitabineP-glycoprotein 1transporter
GemcitabineMultidrug resistance-associated protein 7transporter
GemcitabineEquilibrative nucleoside transporter 1transporter
GemcitabineDNAtarget
GemcitabineSodium/nucleoside cotransporter 1transporter
GemcitabineEquilibrative nucleoside transporter 2transporter
GemcitabineSolute carrier family 28 member 3transporter
TeniposideDNA topoisomerase 2-alphatarget
TeniposideCytochrome P450 2C19enzyme
TeniposideCytochrome P450 2C9enzyme
TeniposideCytochrome P450 3A4enzyme
TeniposideMultidrug resistance-associated protein 6transporter
TeniposideATP-binding cassette sub-family G member 2transporter
TeniposideCytochrome P450 3A5enzyme
EpirubicinDNA topoisomerase 2-alphatarget
EpirubicinDNAtarget
EpirubicinMultidrug resistance-associated protein 1transporter
EpirubicinUDP-glucuronosyltransferase 2B7enzyme
EpirubicinCytosolic phospholipase A2enzyme
ChloramphenicolComplement decay-accelerating factortarget
ChloramphenicolDr hemagglutinin structural subunittarget
ChloramphenicolCytochrome P450 2C19enzyme
ChloramphenicolCytochrome P450 3A4enzyme
ChloramphenicolCytochrome P450 3A5enzyme
ChloramphenicolCytochrome P450 3A7enzyme
ChloramphenicolSolute carrier family 22 member 6transporter
Chloramphenicol50S ribosomal protein L16target
ChloramphenicolChloramphenicol acetyltransferase 3enzyme
ChloramphenicolChloramphenicol acetyltransferaseenzyme
ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
NabumetoneProstaglandin G/H synthase 1target
NabumetoneProstaglandin G/H synthase 2target
NabumetoneMyeloperoxidaseenzyme
NabumetoneCytochrome P450 1A2enzyme
NabumetoneCytochrome P450 2C9enzyme
NabumetoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
NabumetoneAldo-keto reductase family 1 member C1enzyme
NabumetoneAldo-keto reductase family 1 member C2enzyme
NabumetoneAldo-keto reductase family 1 member C4enzyme
NabumetoneSerum albumincarrier
KetorolacProstaglandin G/H synthase 1target
KetorolacProstaglandin G/H synthase 2target
KetorolacUDP-glucuronosyltransferase 2B7enzyme
KetorolacCytochrome P450 2C8enzyme
KetorolacCytochrome P450 2C9enzyme
EnoxacinDNA gyrase subunit Atarget
EnoxacinDNA topoisomerase 4 subunit Atarget
EnoxacinDNA topoisomerase 2-alphatarget
EnoxacinCytochrome P450 1A2enzyme
TenoxicamProstaglandin G/H synthase 1target
TenoxicamProstaglandin G/H synthase 2target
TenoxicamCytochrome P450 2C9enzyme
TenoxicamSolute carrier family 22 member 8transporter
FluoxetineSodium-dependent serotonin transportertarget
FluoxetineCytochrome P450 2C9enzyme
FluoxetineCytochrome P450 2D6enzyme
FluoxetineCYP2B proteinenzyme
FluoxetineCytochrome P450 1A2enzyme
FluoxetineCytochrome P450 3A4enzyme
FluoxetineCytochrome P450 2C19enzyme
FluoxetineP-glycoprotein 1transporter
FluoxetineCytochrome P450 2B6enzyme
FluoxetineCytochrome P450 3A5enzyme
FluoxetineSerum albumincarrier
FluoxetineAlpha-1-acid glycoprotein 1carrier
FluoxetinePotassium voltage-gated channel subfamily H member 2target
Fluoxetine5-hydroxytryptamine receptor 2Ctarget
FluoxetineCyclin-dependent kinases regulatory subunit 1target
FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
FluoxetineNeuronal acetylcholine receptor subunit beta-4target
RimantadineMatrix protein 2target
CelecoxibProstaglandin G/H synthase 2target
Celecoxib3-phosphoinositide-dependent protein kinase 1target
CelecoxibCytochrome P450 2C9enzyme
CelecoxibCytochrome P450 2D6enzyme
CelecoxibMultidrug resistance-associated protein 4transporter
CelecoxibCytochrome P450 3A4enzyme
CelecoxibCytochrome P450 2C8enzyme
CelecoxibCarbonic anhydrase 2target
CelecoxibCarbonic anhydrase 3target
CelecoxibBile salt export pumptransporter
CelecoxibCadherin-11target
CelecoxibP-glycoprotein 1transporter
CelecoxibATP-binding cassette sub-family G member 2transporter
PefloxacinDNA gyrase subunit Atarget
PefloxacinDNA topoisomerase 4 subunit Atarget
PefloxacinDNA topoisomerase 2-alphatarget
PefloxacinCytochrome P450 1A2enzyme
PefloxacinDNA topoisomerase 1target
MiglitolMaltase-glucoamylase, intestinaltarget
MiglitolPancreatic alpha-amylaseenzyme
MiglitolLysosomal alpha-glucosidasetarget
MiglitolNeutral alpha-glucosidase ABtarget
MiglitolNeutral alpha-glucosidase Ctarget
FosinoprilAngiotensin-converting enzymetarget
FosinoprilSolute carrier family 15 member 1transporter
FosinoprilSolute carrier family 15 member 2transporter
EntacaponeCatechol O-methyltransferasetarget
EntacaponeCatechol O-methyltransferaseenzyme
EntacaponeUDP-glucuronosyltransferase 1-9enzyme
EntacaponeCytochrome P450 2D6enzyme
ZidovudineSerum albumincarrier
ZidovudineCytochrome P450 2A6enzyme
ZidovudineCytochrome P450 2C9enzyme
ZidovudineCytochrome P450 3A4enzyme
ZidovudineReverse transcriptase/RNaseHtarget
ZidovudineSolute carrier family 22 member 2transporter
ZidovudineSolute carrier family 22 member 6transporter
ZidovudineSolute carrier family 22 member 7transporter
ZidovudineSolute carrier family 22 member 8transporter
ZidovudineSolute carrier family 22 member 11transporter
ZidovudineSodium/nucleoside cotransporter 1transporter
ZidovudineEquilibrative nucleoside transporter 2transporter
ZidovudineP-glycoprotein 1transporter
ZidovudineMultidrug resistance-associated protein 4transporter
ZidovudineMultidrug resistance-associated protein 5transporter
ZidovudineATP-binding cassette sub-family G member 2transporter
ZidovudineTelomerase reverse transcriptasetarget
ZidovudineThymidine kinase, cytosolicenzyme
ZidovudineUDP-glucuronosyltransferase 2B7enzyme
ZidovudineUDP-glucuronosyltransferase 1-1enzyme
TolmetinProstaglandin G/H synthase 1target
TolmetinProstaglandin G/H synthase 2target
TolmetinSolute carrier family 22 member 6transporter
TolmetinTryptophan 2,3-dioxygenaseenzyme
TolmetinMyeloperoxidaseenzyme
TolmetinSerum albumincarrier
CimetidineHistamine H2 receptortarget
CimetidineCytochrome P450 1A2enzyme
CimetidineCytochrome P450 2D6enzyme
CimetidineCytochrome P450 2C19enzyme
CimetidineCytochrome P450 3A4enzyme
CimetidineCytochrome P450 3A5enzyme
CimetidineP-glycoprotein 1transporter
CimetidineSolute carrier family 22 member 2transporter
CimetidineSolute carrier family 22 member 1transporter
CimetidineSolute carrier family 22 member 3transporter
CimetidineSolute carrier family 22 member 5transporter
CimetidineSolute carrier family 22 member 6transporter
CimetidineSolute carrier family 22 member 8transporter
CimetidineMultidrug and toxin extrusion protein 1transporter
CimetidineSolute carrier family 22 member 4transporter
CimetidineSolute carrier family 22 member 11transporter
CimetidineSolute carrier family 22 member 7transporter
CimetidineCytochrome P450 11B1, mitochondrialenzyme
CimetidineCytochrome P450 2C8enzyme
CimetidineCytochrome P450 2C9enzyme
CimetidineCytochrome P450 2E1enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
CimetidineBile salt export pumptransporter
CimetidineMultidrug and toxin extrusion protein 2transporter
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
AcetyldigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
TrandolaprilAngiotensin-converting enzymetarget
TrandolaprilSolute carrier family 15 member 1transporter
TrandolaprilSolute carrier family 15 member 2transporter
TrandolaprilLiver carboxylesterase 1enzyme
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetSolute carrier family 22 member 6transporter
FoscarnetMonocarboxylate transporter 1transporter
ErlotinibEpidermal growth factor receptortarget
ErlotinibCytochrome P450 3A4enzyme
ErlotinibATP-binding cassette sub-family G member 2transporter
ErlotinibP-glycoprotein 1transporter
ErlotinibNuclear receptor subfamily 1 group I member 2target
ErlotinibCytochrome P450 3A5enzyme
ErlotinibCytochrome P450 1A1enzyme
ErlotinibCytochrome P450 1A2enzyme
ErlotinibCytochrome P450 1B1enzyme
ErlotinibCytochrome P450 2D6enzyme
ErlotinibCytochrome P450 2C8enzyme
ErlotinibUDP-glucuronosyltransferase 1-1enzyme
ErlotinibSerum albumincarrier
ErlotinibAlpha-1-acid glycoprotein 1carrier
ErlotinibSolute carrier organic anion transporter family member 2B1transporter
RofecoxibProstaglandin G/H synthase 2target
RofecoxibElastintarget
RofecoxibCytochrome P450 3A4enzyme
RofecoxibCytochrome P450 1A2enzyme
RofecoxibMultidrug resistance-associated protein 4transporter
RofecoxibProstaglandin G/H synthase 1enzyme
RofecoxibCytochrome P450 2C8enzyme
RofecoxibCytochrome P450 2C9enzyme
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Atarget
CiprofloxacinDNA topoisomerase 2-alphatarget
CiprofloxacinCytochrome P450 1A2enzyme
CiprofloxacinCytochrome P450 3A4enzyme
CiprofloxacinCytochrome P450 3A5enzyme
CiprofloxacinCytochrome P450 3A7enzyme
CiprofloxacinP-glycoprotein 1transporter
CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Btarget
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinMultidrug resistance protein MdtKtarget
CiprofloxacinGyrase Atarget
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinMultidrug and toxin extrusion protein 1transporter
CiprofloxacinMultidrug and toxin extrusion protein 2transporter
CiprofloxacinSerum albumincarrier
BenazeprilAngiotensin-converting enzymetarget
BenazeprilMethylenetetrahydrofolate reductaseenzyme
BenazeprilSolute carrier family 15 member 1transporter
BenazeprilSolute carrier family 15 member 2transporter
PyridostigmineAcetylcholinesterasetarget
PyridostigmineCholinesterasetarget
PyridostigmineSerum albumintarget
Acetohydroxamic acidUrease subunit alphatarget
Acetohydroxamic acidMacrophage metalloelastasetarget
PentostatinAdenosine deaminasetarget
PiroxicamProstaglandin G/H synthase 1target
PiroxicamProstaglandin G/H synthase 2target
PiroxicamSerum albumincarrier
PiroxicamCytochrome P450 2C9enzyme
PiroxicamSolute carrier family 22 member 6transporter
PiroxicamSolute carrier family 22 member 8transporter
PiroxicamSolute carrier family 22 member 11transporter
PiroxicamCytochrome P450 2C8enzyme
PiroxicamSolute carrier organic anion transporter family member 2B1transporter
ZanamivirNeuraminidasetarget
ZanamivirNeuraminidasetarget
ZanamivirSialidase-2target
MethotrexateDihydrofolate reductasetarget
MethotrexateAldehyde oxidaseenzyme
MethotrexateMethylenetetrahydrofolate reductaseenzyme
MethotrexateSerum albumincarrier
MethotrexateCanalicular multispecific organic anion transporter 2transporter
MethotrexateMultidrug resistance-associated protein 4transporter
MethotrexateMultidrug resistance-associated protein 1transporter
MethotrexateSolute carrier family 22 member 6transporter
MethotrexateMultidrug resistance-associated protein 7transporter
MethotrexateSolute carrier family 22 member 8transporter
MethotrexateCanalicular multispecific organic anion transporter 1transporter
MethotrexateP-glycoprotein 1transporter
MethotrexateSolute carrier organic anion transporter family member 1A2transporter
MethotrexateMonocarboxylate transporter 1transporter
MethotrexateATP-binding cassette sub-family C member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1B3transporter
MethotrexateSolute carrier family 22 member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1C1transporter
MethotrexateSolute carrier organic anion transporter family member 3A1transporter
MethotrexateATP-binding cassette sub-family G member 2transporter
MethotrexateSolute carrier family 22 member 7transporter
MethotrexateSolute carrier organic anion transporter family member 1B1transporter
Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MethotrexateProton-coupled folate transportertransporter
MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
MethotrexateGamma-glutamyl hydrolaseenzyme
MethotrexateDihydrofolate reductaseenzyme
MethotrexateThymidylate synthaseenzyme
MethotrexateBifunctional purine biosynthesis protein PURHenzyme
MethotrexateSolute carrier organic anion transporter family member 4C1transporter
MethotrexateFolate transporter 1transporter
MethotrexateFolate receptor alphatransporter
MethotrexateCytochrome P450 3A4enzyme
MethotrexateThymidylate synthasetarget
MethotrexateBifunctional purine biosynthesis protein PURHtarget
MethotrexateFolate receptor betatransporter
MethotrexateSolute carrier family 15 member 1transporter
MethotrexateProton-coupled amino acid transporter 1transporter
FenoprofenProstaglandin G/H synthase 1target
FenoprofenProstaglandin G/H synthase 2target
FenoprofenSerum albumincarrier
FenoprofenPeroxisome proliferator-activated receptor alphatarget
FenoprofenPeroxisome proliferator-activated receptor gammatarget
ValdecoxibProstaglandin G/H synthase 2target
ValdecoxibCytochrome P450 2C9enzyme
ValdecoxibCytochrome P450 3A4enzyme
ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
ValdecoxibCarbonic anhydrase 2target
ValdecoxibCarbonic anhydrase 3target
VoriconazoleCytochrome P450 2C19enzyme
VoriconazoleCytochrome P450 3A4enzyme
VoriconazoleCytochrome P450 2C9enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
VoriconazoleCytochrome P450 3A5enzyme
VoriconazoleCytochrome P450 3A7enzyme
VoriconazoleProstaglandin G/H synthase 1enzyme
VoriconazoleCytochrome P450 51target
VoriconazoleCytochrome P450 2B6enzyme
EnalaprilAngiotensin-converting enzymetarget
EnalaprilP-glycoprotein 1transporter
EnalaprilSolute carrier family 15 member 1transporter
EnalaprilSolute carrier family 22 member 6transporter
EnalaprilSolute carrier family 22 member 8transporter
EnalaprilSolute carrier family 22 member 7transporter
EnalaprilSolute carrier organic anion transporter family member 1A2transporter
EnalaprilSerum albumincarrier
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
Linezolid23S ribosomal RNAtarget
LinezolidAmine oxidase [flavin-containing] Aenzyme
LinezolidAmine oxidase [flavin-containing] Benzyme
SulindacProstaglandin G/H synthase 2target
SulindacAldose reductasetarget
SulindacProstaglandin G/H synthase 1target
SulindacMitogen-activated protein kinase 3target
SulindacPeroxisome proliferator-activated receptor deltatarget
SulindacProstaglandin D2 receptor 2target
SulindacSerum albumincarrier
SulindacSolute carrier family 22 member 6transporter
SulindacCytochrome P450 1A1enzyme
SulindacAldo-keto reductase family 1 member B10target
FurazolidoneDNAtarget
FurazolidoneAmine oxidase [flavin-containing] Benzyme
FurazolidoneAmine oxidase [flavin-containing] Aenzyme
CandoxatrilNeprilysintarget
CandoxatrilAngiotensin-converting enzymetarget
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
TriamcinoloneCorticosteroid-binding globulincarrier
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneSerum albumincarrier
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzSerum albumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1-1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
Simvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
SimvastatinCytochrome P450 3A4enzyme
SimvastatinCytochrome P450 2C8enzyme
SimvastatinCytochrome P450 2C9enzyme
SimvastatinCytochrome P450 3A5enzyme
SimvastatinP-glycoprotein 1transporter
SimvastatinSolute carrier organic anion transporter family member 1A2transporter
SimvastatinSolute carrier organic anion transporter family member 1B1transporter
SimvastatinCytochrome P450 2B6enzyme
SimvastatinCytochrome P450 2D6enzyme
SimvastatinUDP-glucuronosyltransferase 1-1enzyme
SimvastatinUDP-glucuronosyltransferase 1-3enzyme
SimvastatinUDP-glucuronosyltransferase 2B7enzyme
SimvastatinCanalicular multispecific organic anion transporter 1transporter
SimvastatinIntegrin alpha-Ltarget
SimvastatinBile salt export pumptransporter
SimvastatinCytochrome P450 2C19enzyme
SimvastatinSolute carrier organic anion transporter family member 2B1transporter
SimvastatinSolute carrier organic anion transporter family member 1B3transporter
SimvastatinHistone deacetylase 2target
PemetrexedThymidylate synthasetarget
PemetrexedDihydrofolate reductasetarget
PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
PemetrexedDeoxycytidine kinaseenzyme
PemetrexedBifunctional purine biosynthesis protein PURHtarget
PemetrexedEquilibrative nucleoside transporter 1enzyme
PemetrexedSolute carrier family 22 member 8transporter
StavudineSolute carrier family 22 member 6transporter
StavudineReverse transcriptase/RNaseHtarget
StavudineSodium/nucleoside cotransporter 1transporter
StavudineSerum albumincarrier
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DyphyllineAdenosine receptor A1target
DyphyllineAdenosine receptor A2atarget
GalantamineAcetylcholinesterasetarget
GalantamineCytochrome P450 3A4enzyme
GalantamineCytochrome P450 2D6enzyme
GalantamineCholinesterasetarget
GalantamineP-glycoprotein 1transporter
GalantamineNeuronal acetylcholine receptor subunit alpha-7target
GalantamineMuscle nicotinic acetylcholine receptortarget
IsoflurophateCholinesterasetarget
IsoflurophateAcetylcholinesterasetarget
IsoflurophateCholinesteraseenzyme
IsoflurophateSerum albumincarrier
IsoflurophateSerotransferrintarget
TrovafloxacinDNA gyrase subunit Atarget
TrovafloxacinDNA topoisomerase 4 subunit Atarget
TrovafloxacinDNA topoisomerase 2-alphatarget
TrovafloxacinCytochrome P450 1A2enzyme
MoexiprilAngiotensin-converting enzymetarget
MoexiprilSolute carrier family 15 member 1transporter
MoexiprilSolute carrier family 15 member 2transporter
DaunorubicinDNAtarget
DaunorubicinXanthine dehydrogenase/oxidaseenzyme
DaunorubicinCytochrome P450 3A5enzyme
DaunorubicinNADPH--cytochrome P450 reductaseenzyme
DaunorubicinP-glycoprotein 1transporter
DaunorubicinMultidrug resistance-associated protein 1transporter
DaunorubicinCanalicular multispecific organic anion transporter 1transporter
DaunorubicinMultidrug resistance-associated protein 6transporter
DaunorubicinBile salt export pumptransporter
DaunorubicinMultidrug resistance-associated protein 7transporter
DaunorubicinATP-binding cassette sub-family G member 2transporter
DaunorubicinDNA topoisomerase 2-alphatarget
DaunorubicinDNA topoisomerase 2-betatarget
DaunorubicinCytochrome P450 1A1enzyme
DaunorubicinCytochrome P450 1B1enzyme
DaunorubicinCytochrome P450 3A4enzyme
AmprenavirHuman immunodeficiency virus type 1 proteasetarget
AmprenavirCytochrome P450 3A4enzyme
AmprenavirP-glycoprotein 1transporter
AmprenavirMultidrug resistance-associated protein 1transporter
AmprenavirCytochrome P450 2B6enzyme
AmprenavirCytochrome P450 2C19enzyme
AmprenavirCytochrome P450 2C9enzyme
AmprenavirCytochrome P450 2D6enzyme
AmprenavirCytochrome P450 3A5enzyme
AmprenavirSolute carrier organic anion transporter family member 1B1transporter
MethazolamideCarbonic anhydrase 1target
MethazolamideSolute carrier family 22 member 6transporter
MethazolamideCarbonic anhydrase 4target
MethazolamideCarbonic anhydrase 2target
MethazolamideCarbonic anhydrase 7target
MethazolamideCarbonic anhydrase 3target
DelavirdineCytochrome P450 3A4enzyme
DelavirdineCytochrome P450 2C9enzyme
DelavirdineCytochrome P450 2D6enzyme
DelavirdineCytochrome P450 3A5enzyme
DelavirdineCytochrome P450 3A7enzyme
DelavirdineCytochrome P450 2C19enzyme
DelavirdineReverse transcriptase/RNaseHtarget
LamivudineDNAtarget
LamivudineProtein Ptarget
LamivudineMultidrug resistance-associated protein 1transporter
LamivudineSolute carrier family 22 member 6transporter
LamivudineATP-binding cassette sub-family G member 2transporter
LamivudineReverse transcriptase/RNaseHtarget
LamivudineSolute carrier family 22 member 1transporter
LamivudineSolute carrier family 22 member 2transporter
LamivudineSolute carrier family 22 member 3transporter
LamivudineDeoxycytidine kinaseenzyme
LamivudineUMP-CMP kinaseenzyme
LamivudinePhosphoglycerate kinase 1enzyme
LamivudineNucleoside diphosphate kinase Aenzyme
LamivudineNucleoside diphosphate kinase Benzyme
LamivudineCholine-phosphate cytidylyltransferase Aenzyme
LamivudineEthanolamine-phosphate cytidylyltransferaseenzyme
LamivudineP-glycoprotein 1transporter
LamivudineMultidrug resistance-associated protein 4transporter
LamivudineCanalicular multispecific organic anion transporter 2transporter
LamivudineCanalicular multispecific organic anion transporter 1transporter
Lamivudine5'(3')-deoxyribonucleotidase, cytosolic typeenzyme
LamivudineSerum albumincarrier
DiethylcarbamazineArachidonate 5-lipoxygenasetarget
DiethylcarbamazineProstaglandin G/H synthase 1target
DiethylcarbamazineCholinesteraseenzyme
FlurbiprofenProstaglandin G/H synthase 2target
FlurbiprofenProstaglandin G/H synthase 1target
FlurbiprofenCytochrome P450 2C9enzyme
FlurbiprofenSerum albumincarrier
FlurbiprofenMultidrug resistance-associated protein 4transporter
FlurbiprofenSolute carrier family 22 member 6transporter
FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
ParoxetineSodium-dependent serotonin transportertarget
ParoxetineSodium-dependent noradrenaline transportertarget
Paroxetine5-hydroxytryptamine receptor 2Atarget
ParoxetineCytochrome P450 2D6enzyme
ParoxetineCytochrome P450 2C9enzyme
ParoxetineP-glycoprotein 1transporter
ParoxetineCytochrome P450 2B6enzyme
ParoxetineCytochrome P450 1A2enzyme
ParoxetineCytochrome P450 3A4enzyme
ParoxetineAlpha-1 adrenergic receptorstarget
ParoxetineAlpha-2 adrenergic receptorstarget
ParoxetineBeta adrenergic receptortarget
ParoxetineDopamine D2 receptortarget
ParoxetineHistamine H1 receptortarget
ParoxetineSerotonin Receptorstarget
ParoxetineMuscarinic acetylcholine receptortarget
Paroxetine5-hydroxytryptamine receptor 2Btarget
ParoxetineD(1) dopamine receptortarget
ParoxetineCytochrome P450 2C19enzyme
Adefovir dipivoxilDNA polymerase/reverse transcriptasetarget
Adefovir dipivoxilSolute carrier family 22 member 6transporter
Adefovir dipivoxilMultidrug resistance-associated protein 4transporter
Adefovir dipivoxilMultidrug resistance-associated protein 5transporter
Adefovir dipivoxilSolute carrier family 22 member 3transporter
Adefovir dipivoxilAdenylate kinase 2, mitochondrialenzyme
Adefovir dipivoxilAdenylate kinase 4, mitochondrialenzyme
Adefovir dipivoxilNucleoside diphosphate kinase Aenzyme
Adefovir dipivoxilNucleoside diphosphate kinase Benzyme
LisinoprilAngiotensin-converting enzymetarget
LisinoprilSolute carrier family 15 member 1transporter
LisinoprilSolute carrier family 15 member 2transporter
LisinoprilRenintarget
EsomeprazolePotassium-transporting ATPase alpha chain 1target
EsomeprazoleCytochrome P450 2C19enzyme
EsomeprazoleCytochrome P450 3A4enzyme
EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
EsomeprazoleP-glycoprotein 1transporter
EsomeprazoleSolute carrier family 22 member 8transporter
ZileutonArachidonate 5-lipoxygenasetarget
ZileutonCytochrome P450 2C9enzyme
ZileutonCytochrome P450 1A2enzyme
ZileutonCytochrome P450 3A4enzyme
ZileutonProstaglandin G/H synthase 1enzyme
ZileutonUDP-glucuronosyltransferase 1-9enzyme
ZileutonSerum albumincarrier
EtodolacProstaglandin G/H synthase 1target
EtodolacProstaglandin G/H synthase 2target
EtodolacCytochrome P450 2C9enzyme
EtodolacUDP-glucuronosyltransferase 1-9enzyme
EtodolacRetinoic acid receptor RXR-alphatarget
EtodolacSerum albumincarrier
EtodolacSolute carrier family 22 member 6transporter
EtodolacUDP-glucuronosyltransferase 1-3enzyme
EtodolacUDP-glucuronosyltransferase 1-10enzyme
EtodolacUDP-glucuronosyltransferase 2B7enzyme
TranylcypromineAmine oxidase [flavin-containing] Btarget
TranylcypromineAmine oxidase [flavin-containing] Atarget
TranylcypromineCytochrome P450 2C19enzyme
TranylcypromineCytochrome P450 2A6enzyme
TranylcypromineCytochrome P450 2D6enzyme
TranylcypromineCytochrome P450 1A2enzyme
TranylcypromineCytochrome P450 2C9enzyme
TranylcypromineCytochrome P450 2E1enzyme
Tetracycline16S ribosomal RNAtarget
TetracyclineMajor prion proteintarget
TetracyclineSerum albumincarrier
TetracyclineCytochrome P450 3A4enzyme
TetracyclineSolute carrier family 22 member 6transporter
TetracyclineSolute carrier family 22 member 8transporter
TetracyclineSolute carrier family 22 member 11transporter
TetracyclineSolute carrier family 22 member 7transporter
Tetracycline30S ribosomal protein S3target
Tetracycline30S ribosomal protein S8target
Tetracycline30S ribosomal protein S19target
Tetracycline30S ribosomal protein S14target
Tetracycline30S ribosomal protein S7target
TetracyclineMultidrug translocase MdfAtarget
TetracyclineProtein-arginine deiminase type-4target
TetracyclineSolute carrier organic anion transporter family member 2B1transporter
IrinotecanDNA topoisomerase I, mitochondrialtarget
IrinotecanDNA topoisomerase 1target
IrinotecanCytochrome P450 3A4enzyme
IrinotecanCytochrome P450 3A5enzyme
IrinotecanUDP-glucuronosyltransferase 1-1enzyme
IrinotecanUDP-glucuronosyltransferase 1-9enzyme
IrinotecanLiver carboxylesterase 1enzyme
IrinotecanCytochrome P450 3A7enzyme
IrinotecanCytochrome P450 2B6enzyme
IrinotecanSolute carrier family 22 member 3transporter
IrinotecanSolute carrier organic anion transporter family member 1B1transporter
IrinotecanMultidrug resistance-associated protein 1transporter
IrinotecanATP-binding cassette sub-family G member 2transporter
IrinotecanSerum albumincarrier
IrinotecanCocaine esteraseenzyme
IrinotecanCholinesteraseenzyme
IrinotecanP-glycoprotein 1transporter
IrinotecanCanalicular multispecific organic anion transporter 1transporter
MetyrosineTyrosine 3-monooxygenasetarget
Clavulanic acidBacterial beta-lactamase enzymesenzyme
Clavulanic acidBacterial beta-lactamase enzymestarget
Clavulanic acidSodium/glucose cotransporter 1transporter
MalathionCholinesterasetarget
MalathionCytochrome P450 1A2enzyme
MalathionCytochrome P450 2B6enzyme
EtoposideDNA topoisomerase 2-alphatarget
EtoposideCytochrome P450 3A4enzyme
EtoposideCanalicular multispecific organic anion transporter 2transporter
EtoposideMultidrug resistance-associated protein 6transporter
EtoposideP-glycoprotein 1transporter
EtoposideMultidrug resistance-associated protein 1transporter
EtoposideMultidrug resistance-associated protein 7transporter
EtoposideCanalicular multispecific organic anion transporter 1transporter
EtoposideATP-binding cassette sub-family G member 2transporter
EtoposideCytochrome P450 1A2enzyme
EtoposideCytochrome P450 2E1enzyme
EtoposideCytochrome P450 3A5enzyme
EtoposideUDP-glucuronosyltransferase 1-1enzyme
EtoposideDNA topoisomerase 2-betatarget
EtoposideGlutathione S-transferase theta-1enzyme
EtoposideGlutathione S-transferase Penzyme
EtoposideProstaglandin G/H synthase 2enzyme
EtoposideProstaglandin G/H synthase 1enzyme
Nalidixic acidDNAtarget
Nalidixic acidSolute carrier family 22 member 6transporter
Nalidixic acidTryptophan 2,3-dioxygenaseenzyme
Nalidixic acidCytochrome P450 1A2enzyme
PhenelzineMembrane primary amine oxidasetarget
PhenelzineAmine oxidase [flavin-containing] Btarget
PhenelzineAmine oxidase [flavin-containing] Atarget
PhenelzineAmine oxidase [flavin-containing] Aenzyme
PhenelzineAmine oxidase [flavin-containing] Benzyme
PhenelzineCytochrome P450 2E1enzyme
Phenelzine4-aminobutyrate aminotransferase, mitochondrialtarget
PhenelzineGlutamic acid decarboxylasetarget
PhenelzineAlanine aminotransferase 1target
PhenelzineAlanine aminotransferase 2target
PhenelzineCytochrome P450 2C19enzyme
PhenelzineCytochrome P450 2C8enzyme
PhenelzineCytochrome P450 3A4enzyme
PhenelzineCytochrome P450 3A5enzyme
PhenelzineCytochrome P450 3A7enzyme
PhenelzineCytochrome P450 2D6enzyme
PhenelzineCytochrome P450 3A Subfamilyenzyme
Mefenamic acidProstaglandin G/H synthase 2target
Mefenamic acidProstaglandin G/H synthase 1target
Mefenamic acidCytochrome P450 2C9enzyme
Mefenamic acidCytochrome P450 2C8enzyme
Mefenamic acidSerum albumincarrier
Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
Marimastat72 kDa type IV collagenasetarget
MarimastatMatrix metalloproteinase-9target
MarimastatStromelysin-1target
MarimastatInterstitial collagenasetarget
MarimastatStromelysin-2target
MarimastatMatrilysintarget
MarimastatNeutrophil collagenasetarget
MarimastatStromelysin-3target
MarimastatMacrophage metalloelastasetarget
MarimastatCollagenase 3target
MarimastatMatrix metalloproteinase-14target
MarimastatMatrix metalloproteinase-15target
MarimastatMatrix metalloproteinase-16target
MarimastatMatrix metalloproteinase-17target
MarimastatMatrix metalloproteinase-19target
MarimastatMatrix metalloproteinase-20target
MarimastatMatrix metalloproteinase-21target
MarimastatMatrix metalloproteinase-23target
MarimastatMatrix metalloproteinase-24target
MarimastatMatrix metalloproteinase-25target
MarimastatMatrix metalloproteinase-26target
MarimastatMatrix metalloproteinase-27target
MarimastatMatrix metalloproteinase-28target
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
PerindoprilAngiotensin-converting enzymetarget
PerindoprilSolute carrier family 15 member 1transporter
PerindoprilSolute carrier family 15 member 2transporter
PerindoprilCholinesteraseenzyme
PerindoprilSecreted frizzled-related protein 4target
Gentamicin30S ribosomal protein S12target
Gentamicin16S ribosomal RNAtarget
GentamicinLow-density lipoprotein receptor-related protein 2target
GentamicinSolute carrier family 22 member 6transporter
GentamicinNH(3)-dependent NAD(+) synthetasetarget
GentamicinDihydrofolate reductasetarget
Pentoxifylline5'-nucleotidasetarget
PentoxifyllineAdenosine receptor A1target
PentoxifyllineAdenosine receptor A2atarget
PentoxifyllineCytochrome P450 1A2enzyme
PentoxifyllinePhosphodiesterase enzymestarget
AcetazolamideCarbonic anhydrase 1target
AcetazolamideAquaporin-1target
AcetazolamideCarbonic anhydrase 14target
AcetazolamideSolute carrier family 22 member 6transporter
AcetazolamideCarbonic anhydrase 2target
AcetazolamideCarbonic anhydrase 3target
AcetazolamideCarbonic anhydrase 4target
AcetazolamideCytochrome P450 3A4enzyme
AcetazolamideCarbonic anhydrase 7target
AcetazolamideCarbonic anhydrase 12target
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilCytochrome P450 3A5enzyme
DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DisulfiramCytochrome P450 2E1enzyme
DisulfiramDopamine beta-hydroxylasetarget
DisulfiramCytochrome P450 3A4enzyme
DisulfiramCytochrome P450 3A5enzyme
DisulfiramBile salt export pumptransporter
CinoxacinDNAtarget
CinoxacinDNA gyrase subunit Atarget
CinoxacinSolute carrier family 22 member 6transporter
CinoxacinCytochrome P450 1A2enzyme
DonepezilAcetylcholinesterasetarget
Donepezil5-hydroxytryptamine receptor 2Atarget
DonepezilCytochrome P450 3A4enzyme
DonepezilCytochrome P450 2D6enzyme
DonepezilCytochrome P450 2C9enzyme
DonepezilCholinesterasetarget
DonepezilNitric oxide synthase, braintarget
DonepezilTumor necrosis factor-inducible gene 6 proteintarget
DonepezilInterleukin-1 betatarget
DonepezilNuclear factor NF-kappa-Btarget
DonepezilATP-binding cassette sub-family G member 2transporter
DonepezilNMDA receptortarget
TerbinafineSqualene monooxygenasetarget
TerbinafineCytochrome P450 2D6enzyme
TerbinafineCytochrome P450 2C9enzyme
TerbinafineCytochrome P450 1A2enzyme
TerbinafineCytochrome P450 3A4enzyme
TerbinafineCytochrome P450 2C8enzyme
TerbinafineCytochrome P450 2C19enzyme
TerbinafineProstaglandin G/H synthase 1enzyme
TerbinafineSerum albumincarrier
Terbinafinealpha1-acid glycoproteincarrier
TerbinafineABC multidrug transporter MDR2transporter
TerbinafineSqualene monooxygenasetarget
DiflunisalProstaglandin G/H synthase 1target
DiflunisalProstaglandin G/H synthase 2target
DiflunisalTransthyretincarrier
DiflunisalSerum albumincarrier
DiflunisalSolute carrier family 22 member 6transporter
DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DiflunisalUDP-glucuronosyltransferase 1-9enzyme
VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
VardenafilCytochrome P450 3A4enzyme
VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilCytochrome P450 3A5enzyme
VardenafilP-glycoprotein 1transporter
TacrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
TacrolimusCytochrome P450 3A4enzyme
TacrolimusCytochrome P450 3A5enzyme
TacrolimusP-glycoprotein 1transporter
TacrolimusATP-binding cassette sub-family A member 5transporter
TacrolimusSerum albumincarrier
TacrolimusAlpha-1-acid glycoprotein 1carrier
TacrolimusSolute carrier organic anion transporter family member 1B1transporter
DorzolamideCarbonic anhydrase 2target
DorzolamideCarbonic anhydrase 1target
DorzolamideCarbonic anhydrase 4target
DorzolamideCytochrome P450 2C9enzyme
DorzolamideCarbonic anhydrase 3target
DorzolamideCytochrome P450 2B1enzyme
DorzolamideCytochrome P450 2E1enzyme
DorzolamideCytochrome P450 3A2enzyme
SuprofenProstaglandin G/H synthase 1target
SuprofenProstaglandin G/H synthase 2target
SuprofenCytochrome P450 2C9enzyme
SuprofenUDP-glucuronosyltransferase 1-1enzyme
SuprofenSolute carrier family 22 member 12transporter
SuprofenUDP-glucuronosyltransferase 2B7enzyme
SuprofenSerum albumincarrier
EmtricitabineReverse transcriptase/RNaseHtarget
EmtricitabineDeoxycytidine kinaseenzyme
EmtricitabineSerum albumincarrier
EmtricitabineMultidrug and toxin extrusion protein 1transporter
QuinaprilAngiotensin-converting enzymetarget
QuinaprilSolute carrier family 15 member 1transporter
QuinaprilSolute carrier family 15 member 2transporter
QuinaprilSolute carrier family 22 member 8transporter
QuinaprilLiver carboxylesterase 1enzyme
QuinaprilSerum albumincarrier
OmapatrilatNeprilysintarget
OmapatrilatAngiotensin-converting enzymetarget
DidanosineSolute carrier family 22 member 6transporter
DidanosinePurine nucleoside phosphorylasetarget
DidanosineReverse transcriptase/RNaseHtarget
DidanosineEquilibrative nucleoside transporter 1transporter
DidanosineEquilibrative nucleoside transporter 2transporter
DidanosineSerum albumincarrier
Etacrynic acidSolute carrier family 12 member 1target
Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1target
Etacrynic acidGlutathione S-transferase A2enzyme
Etacrynic acidSerum albumincarrier
Etacrynic acidSolute carrier family 22 member 6transporter
Etacrynic acidLymphoid enhancer-binding factor 1target
Etacrynic acidGlutathione S-transferase Ptarget
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
QuinidineSerum albumincarrier
LevosimendanTroponin C, slow skeletal and cardiac musclestarget
LevosimendanATP-sensitive inward rectifier potassium channel 11target
LevosimendanATP-sensitive inward rectifier potassium channel 8target
LevosimendancGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AzacitidineDNA (cytosine-5)-methyltransferase 1target
AzacitidineCytidine deaminaseenzyme
AzacitidineDNAtarget
AzacitidineRNAtarget
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidArachidonate 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
ZalcitabineDeoxycytidine kinaseenzyme
ZalcitabineSolute carrier family 22 member 6transporter
ZalcitabineSolute carrier family 22 member 7transporter
ZalcitabineReverse transcriptase/RNaseHtarget
ZalcitabineEquilibrative nucleoside transporter 1transporter
ZalcitabineEquilibrative nucleoside transporter 2transporter
ZalcitabineSerum albumincarrier
DemecariumAcetylcholinesterasetarget
DemecariumCholinesterasetarget
Netilmicin30S ribosomal protein S12target
Netilmicin16S ribosomal RNAtarget
DactinomycinDNAtarget
DactinomycinSolute carrier family 22 member 5transporter
DactinomycinP-glycoprotein 1transporter
DactinomycinMultidrug resistance-associated protein 6transporter
DactinomycinMultidrug resistance-associated protein 1transporter
DactinomycinATP-binding cassette sub-family G member 2transporter
DactinomycinDNA topoisomerase 2target
AzelastineHistamine H1 receptortarget
AzelastineCytochrome P450 1A2enzyme
AzelastineCytochrome P450 2D6enzyme
AzelastineCytochrome P450 3A4enzyme
AzelastineCytochrome P450 2C19enzyme
AzelastineCytochrome P450 1A1enzyme
AzelastineCytochrome P450 3A5enzyme
AzelastineCytochrome P450 2C9enzyme
AzelastineCytochrome P450 2C8enzyme
AzelastineP-glycoprotein 1transporter
AzelastineCytochrome P450 2A6enzyme
AzelastineCytochrome P450 2E1enzyme
AzelastineHistamine H2 receptortarget
AzelastinePhospholipase A2target
AzelastineLeukotriene C4 synthasetarget
AzelastineCytochrome P450 2B6enzyme
DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DipyridamoleAdenosine deaminasetarget
DipyridamoleMultidrug resistance-associated protein 4transporter
DipyridamoleMultidrug resistance-associated protein 5transporter
DipyridamoleP-glycoprotein 1transporter
DipyridamoleCalcipressin-1target
DipyridamoleAlpha-1-acid glycoprotein 1target
DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DipyridamoleBile salt export pumptransporter
LomefloxacinDNA gyrase subunit Atarget
LomefloxacinDNA topoisomerase 4 subunit Atarget
LomefloxacinDNA topoisomerase 2-alphatarget
LomefloxacinCytochrome P450 1A2enzyme
LomefloxacinSolute carrier family 22 member 5transporter
LomefloxacinCanalicular multispecific organic anion transporter 1transporter
PhysostigmineAcetylcholinesterasetarget
PhysostigmineNeuronal acetylcholine receptor subunit alpha-4target
PhysostigmineNeuronal acetylcholine receptor subunit beta-2target
RivastigmineAcetylcholinesterasetarget
RivastigmineCholinesterasetarget
ExemestaneCytochrome P450 19A1target
ExemestaneCytochrome P450 3A4enzyme
ExemestaneCytochrome P450 19A1enzyme
Neomycin30S ribosomal protein S12target
Neomycin16S ribosomal RNAtarget
NeomycinExtracellular calcium-sensing receptortarget
DoxorubicinDNA topoisomerase 2-alphatarget
DoxorubicinDNAtarget
DoxorubicinCytochrome P450 3A4enzyme
DoxorubicinCytochrome P450 2D6enzyme
DoxorubicinCytochrome P450 2B6enzyme
DoxorubicinP-glycoprotein 1transporter
DoxorubicinCanalicular multispecific organic anion transporter 2transporter
DoxorubicinMultidrug resistance-associated protein 6transporter
DoxorubicinMultidrug resistance-associated protein 1transporter
DoxorubicinMultidrug resistance-associated protein 7transporter
DoxorubicinATP-binding cassette sub-family G member 2transporter
DoxorubicinBile salt export pumptransporter
DoxorubicinSolute carrier family 22 member 16transporter
DoxorubicinATP-binding cassette sub-family B member 8, mitochondrialtransporter
DoxorubicinCytochrome P450 1B1enzyme
DoxorubicinCarbonyl reductase [NADPH] 1enzyme
DoxorubicinCarbonyl reductase [NADPH] 3enzyme
DoxorubicinAlcohol dehydrogenase [NADP(+)]enzyme
DoxorubicinAldo-keto reductase family 1 member C3enzyme
DoxorubicinNAD(P)H dehydrogenase [quinone] 1enzyme
DoxorubicinXanthine dehydrogenase/oxidaseenzyme
DoxorubicinNitric oxide synthase, endothelialenzyme
DoxorubicinNitric oxide synthase, inducibleenzyme
DoxorubicinNitric oxide synthase, brainenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialenzyme
DoxorubicinNADPH--cytochrome P450 reductaseenzyme
DoxorubicinRalA-binding protein 1transporter
DoxorubicinCanalicular multispecific organic anion transporter 1transporter
DoxorubicinSerum albumincarrier
DoxorubicinNucleolar and coiled-body phosphoprotein 1target
HydroxyureaRibonucleoside-diphosphate reductase large subunittarget
HydroxyureaCytochrome P450 2D6enzyme
LetrozoleCytochrome P450 19A1target
LetrozoleCytochrome P450 3A4enzyme
LetrozoleCytochrome P450 2A6enzyme
LetrozoleCytochrome P450 19A1enzyme
LetrozoleCytochrome P450 2C19enzyme
LetrozoleUDP-glucuronosyltransferase 2B7enzyme
LetrozoleSerum albumincarrier
LetrozoleP-glycoprotein 1transporter
TioconazoleLanosterol 14-alpha demethylasetarget
TioconazoleCytochrome P450 19A1enzyme
TioconazoleCytochrome P450 2C19enzyme
TioconazoleCytochrome P450 2E1enzyme
TioconazoleCytochrome P450 3A4enzyme
TioconazoleCytochrome P450 51target
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
EdrophoniumAcetylcholinesterasetarget
EdrophoniumCholinesterasetarget
MetyraponeCamphor 5-monooxygenasetarget
MetyraponeCytochrome P450 11B2, mitochondrialenzyme
MetyraponeCytochrome P450 2A6enzyme
MetyraponeCytochrome P450 3A4enzyme
MetyraponeCanalicular multispecific organic anion transporter 2transporter
MetyraponeCytochrome P450 11B1, mitochondrialtarget
MetyraponeCytochrome P450 11B1, mitochondrialenzyme
MetyraponeCytochrome P450 2E1enzyme
Mycophenolic acidInosine-5'-monophosphate dehydrogenase 2target
Mycophenolic acidInosine-5'-monophosphate dehydrogenase 1target
Mycophenolic acidUDP-glucuronosyltransferase 1-1enzyme
Mycophenolic acidUDP-glucuronosyltransferase 1-9enzyme
Mycophenolic acidUDP-glucuronosyltransferase 2B7enzyme
Mycophenolic acidUDP-glucuronosyltransferase 1-7enzyme
Mycophenolic acidUDP-glucuronosyltransferase 1-6enzyme
KetoconazoleCytochrome P450 3A4enzyme
KetoconazoleCytochrome P450 2C9enzyme
KetoconazoleCytochrome P450 2C19enzyme
KetoconazoleCytochrome P450 3A5enzyme
KetoconazoleCytochrome P450 1A2enzyme
KetoconazoleCytochrome P450 2C8enzyme
KetoconazoleCytochrome P450 1A1enzyme
KetoconazoleCytochrome P450 2D6enzyme
KetoconazoleBile salt export pumptransporter
KetoconazoleP-glycoprotein 1transporter
KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
KetoconazoleCytochrome P450 1B1enzyme
KetoconazoleCytochrome P450 2A6enzyme
KetoconazoleCytochrome P450 2B6enzyme
KetoconazoleLanosterol 14-alpha demethylasetarget
KetoconazoleAndrogen receptortarget
KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
KetoconazoleSteroid 21-hydroxylasetarget
KetoconazolePotassium voltage-gated channel subfamily H member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 3target
KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
KetoconazoleCytochrome P450 4F12enzyme
KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
KetoconazoleSerum albumincarrier
KetoconazoleSex hormone-binding globulincarrier
KetoconazoleCytochrome P450 19A1enzyme
KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
TopotecanDNA topoisomerase I, mitochondrialtarget
TopotecanDNA topoisomerase 1target
TopotecanATP-binding cassette sub-family G member 2transporter
TopotecanP-glycoprotein 1transporter
TopotecanCytochrome P450 3A4enzyme
TopotecanDNAtarget
TopotecanMultidrug and toxin extrusion protein 1transporter
TopotecanMultidrug and toxin extrusion protein 2transporter
MercaptopurineThiopurine S-methyltransferaseenzyme
MercaptopurineXanthine dehydrogenase/oxidaseenzyme
MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
MercaptopurineSolute carrier family 22 member 8transporter
MercaptopurineMultidrug resistance-associated protein 4transporter
MercaptopurineMultidrug resistance-associated protein 5transporter
MercaptopurineSodium/nucleoside cotransporter 2transporter
MercaptopurineSolute carrier family 28 member 3transporter
MercaptopurineEquilibrative nucleoside transporter 1transporter
MercaptopurineEquilibrative nucleoside transporter 2transporter
MercaptopurineAldehyde oxidaseenzyme
MercaptopurineAmidophosphoribosyltransferasetarget
MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
SelegilineAmine oxidase [flavin-containing] Btarget
SelegilineCytochrome P450 2B6enzyme
SelegilineAmine oxidase [flavin-containing] Atarget
SelegilineCytochrome P450 2A6enzyme
SelegilineCytochrome P450 3A4enzyme
SelegilineP-glycoprotein 1transporter
SelegilineCytochrome P450 1A2enzyme
SelegilineCytochrome P450 2C19enzyme
SelegilineCytochrome P450 2C8enzyme
SelegilineCytochrome P450 2C9enzyme
SelegilineCytochrome P450 2D6enzyme
SelegilineCytochrome P450 2E1enzyme
GatifloxacinSerum albumincarrier
GatifloxacinDNA gyrase subunit Atarget
GatifloxacinDNA gyrase subunit Btarget
GatifloxacinDNA topoisomerase 4 subunit Atarget
GatifloxacinDNA topoisomerase 4 subunit Btarget
GatifloxacinCytochrome P450 1A2enzyme
RifampicinDNA-directed RNA polymerase subunit betatarget
RifampicinNuclear receptor subfamily 1 group I member 2target
RifampicinCytochrome P450 3A4enzyme
RifampicinCytochrome P450 1A2enzyme
RifampicinCytochrome P450 2C8enzyme
RifampicinUDP-glucuronosyltransferase 1-1enzyme
RifampicinCytochrome P450 2C9enzyme
RifampicinCytochrome P450 2B6enzyme
RifampicinCytochrome P450 2C19enzyme
RifampicinCanalicular multispecific organic anion transporter 2transporter
RifampicinMultidrug resistance-associated protein 5transporter
RifampicinP-glycoprotein 1transporter
RifampicinCanalicular multispecific organic anion transporter 1transporter
RifampicinSolute carrier organic anion transporter family member 2B1transporter
RifampicinBile salt export pumptransporter
RifampicinMultidrug resistance-associated protein 1transporter
RifampicinSolute carrier organic anion transporter family member 1A2transporter
RifampicinSolute carrier organic anion transporter family member 1B3transporter
RifampicinSolute carrier family 22 member 7transporter
RifampicinSolute carrier organic anion transporter family member 1B1transporter
RifampicinCytochrome P450 2A6enzyme
RifampicinCytochrome P450 2E1enzyme
RifampicinCytochrome P450 3A43enzyme
RifampicinCytochrome P450 3A7enzyme
RifampicinSolute carrier family 22 member 6transporter
RifampicinSolute carrier family 22 member 8transporter
RifampicinUDP-glucuronosyltransferase 1-9enzyme
RifampicinCytochrome P450 3A5enzyme
RifampicinSerum albumincarrier
Rifampicinalpha1-acid glycoproteincarrier
AbacavirAlcohol dehydrogenase 6enzyme
AbacavirUDP-glucuronosyltransferase 1-1enzyme
AbacavirReverse transcriptase/RNaseHtarget
AbacavirAdenosine kinaseenzyme
AbacavirHLA class I histocompatibility antigen, B-57 alpha chaintarget
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenSerum albumincarrier
IbuprofenMultidrug resistance-associated protein 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenSolute carrier family 22 member 8transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenP-glycoprotein 1transporter
IbuprofenUDP-glucuronosyltransferase 1-3enzyme
IbuprofenUDP-glucuronosyltransferase 1-9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
NovobiocinDNA gyrase subunit Btarget
NovobiocinSolute carrier family 22 member 6transporter
NovobiocinSolute carrier family 22 member 8transporter
NovobiocinSolute carrier family 22 member 11transporter
NovobiocinATP-binding cassette sub-family G member 2transporter
NovobiocinDNA topoisomerase 1target
NovobiocinSolute carrier organic anion transporter family member 1B1transporter
NovobiocinSolute carrier organic anion transporter family member 1B3transporter
NovobiocinSolute carrier organic anion transporter family member 2B1transporter
EchothiophateCholinesterasetarget
EchothiophateSerum albumincarrier
NorfloxacinDNA gyrase subunit Atarget
NorfloxacinDNA topoisomerase 4 subunit Atarget
NorfloxacinDNA topoisomerase 2-alphatarget
NorfloxacinCytochrome P450 1A2enzyme
NorfloxacinCytochrome P450 3A4enzyme
NorfloxacinSolute carrier family 22 member 5transporter
NorfloxacinSolute carrier family 22 member 6transporter
NorfloxacinCytochrome P450 1A1enzyme
AtazanavirHuman immunodeficiency virus type 1 proteasetarget
AtazanavirCytochrome P450 3A4enzyme
AtazanavirCytochrome P450 2C9enzyme
AtazanavirP-glycoprotein 1transporter
AtazanavirMultidrug resistance-associated protein 1transporter
AtazanavirSerum albumincarrier
AtazanavirUDP-glucuronosyltransferase 1-1enzyme
AtazanavirSolute carrier organic anion transporter family member 1B1transporter
AtazanavirSolute carrier organic anion transporter family member 1B3transporter
AtazanavirCytochrome P450 2C8enzyme
AtazanavirBile salt export pumptransporter
Atazanaviralpha1-acid glycoproteincarrier
AtazanavirCytochrome P450 1A2enzyme
AtazanavirSolute carrier organic anion transporter family member 2B1transporter
FludarabineDNA polymerase alpha catalytic subunittarget
FludarabineRibonucleoside-diphosphate reductase large subunittarget
FludarabineEquilibrative nucleoside transporter 1transporter
FludarabineDNAtarget
FludarabineDeoxycytidine kinasetarget
FludarabineSolute carrier family 28 member 3transporter
Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
AtorvastatinCytochrome P450 3A4enzyme
AtorvastatinDipeptidyl peptidase 4target
AtorvastatinCytochrome P450 2D6enzyme
AtorvastatinCytochrome P450 2C9enzyme
AtorvastatinCytochrome P450 2C19enzyme
AtorvastatinCytochrome P450 3A5enzyme
AtorvastatinCytochrome P450 3A7enzyme
AtorvastatinP-glycoprotein 1transporter
AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
AtorvastatinMultidrug resistance-associated protein 4transporter
AtorvastatinMultidrug resistance-associated protein 5transporter
AtorvastatinMultidrug resistance-associated protein 1transporter
AtorvastatinCytochrome P450 2B6enzyme
AtorvastatinCytochrome P450 2C8enzyme
AtorvastatinAryl hydrocarbon receptortarget
AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
AtorvastatinCanalicular multispecific organic anion transporter 1transporter
AtorvastatinBile salt export pumptransporter
AtorvastatinSerum albumincarrier
AtorvastatinHistone deacetylase 2target
AtorvastatinNuclear receptor subfamily 1 group I member 3target
DeslanosideSodium/potassium-transporting ATPase subunit alpha-1target
Streptomycin30S ribosomal protein S12target
Streptomycin16S ribosomal RNAtarget
StreptomycinSolute carrier family 22 member 6transporter
StreptomycinProtein-arginine deiminase type-4target
OrlistatPancreatic triacylglycerol lipasetarget
OrlistatFatty acid synthasetarget
OrlistatGastric triacylglycerol lipasetarget
OrlistatCytochrome P450 3A4enzyme
OrlistatCytosolic phospholipase A2enzyme
OuabainSodium/potassium-transporting ATPase subunit alpha-1target
OuabainSolute carrier organic anion transporter family member 1A2transporter
OuabainSolute carrier family 22 member 8transporter
OuabainSolute carrier organic anion transporter family member 4C1transporter
OuabainSolute carrier organic anion transporter family member 1B3transporter
OuabainSolute carrier organic anion transporter family member 1C1transporter
OuabainSolute carrier organic anion transporter family member 1B1transporter
OuabainSodium/potassium-transporting ATPase subunit alpha-2target
OuabainSodium/potassium-transporting ATPase subunit alpha-3target
LeflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
LeflunomideCytochrome P450 1A2enzyme
LeflunomideCytochrome P450 2C9enzyme
LeflunomideAryl hydrocarbon receptortarget
LeflunomideProtein-tyrosine kinase 2-betatarget
LeflunomideATP-binding cassette sub-family G member 2transporter
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
QuinacrineDNAtarget
Quinacrine85/88 kDa calcium-independent phospholipase A2target
QuinacrineCytosolic phospholipase A2target
QuinacrineInactive phospholipase C-like protein 1target
QuinacrineHistamine N-methyltransferaseenzyme
QuinacrineSolute carrier family 22 member 2transporter
QuinacrineP-glycoprotein 1transporter
QuinacrineCytochrome P450 3A4enzyme
QuinacrineCytochrome P450 3A5enzyme
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2target
TrilostaneEstrogen receptor betatarget
TrilostaneEstrogen receptor alphatarget
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
PapaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
AtovaquoneCytochrome btarget
AtovaquoneCytochrome P450 2C9enzyme
AtovaquoneCytochrome P450 3A4enzyme
AtovaquoneP-glycoprotein 1transporter
AmiodaroneBeta adrenergic receptortarget
AmiodaroneHERG human cardiac K+ channeltarget
AmiodaroneCytochrome P450 2C8enzyme
AmiodaroneCytochrome P450 2C9enzyme
AmiodaroneCytochrome P450 2D6enzyme
AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmiodaroneVoltage gated L-type calcium channeltarget
AmiodaroneCytochrome P450 3A4enzyme
AmiodaroneCytochrome P450 1A2enzyme
AmiodaroneCytochrome P450 1A1enzyme
AmiodaroneP-glycoprotein 1transporter
AmiodaroneCytochrome P450 2C19enzyme
AmiodaroneCytochrome P450 2A6enzyme
AmiodaroneThyroid hormone receptortarget
AmiodaronePeroxisome proliferator-activated receptor gammatarget
AmiodaroneBile salt export pumptransporter
AmiodaroneSolute carrier family 22 member 2transporter
AmiodaroneCytochrome P450 2J2enzyme
AmiodaronePeroxisome proliferator-activated receptor alphatarget
AmiodaronePeroxisome proliferator-activated receptor gamma coactivator 1-betatarget
AmiodaroneSerum albumincarrier
AmbenoniumAcetylcholinesterasetarget
AmbenoniumCholinesteraseenzyme
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DutasterideSodium-dependent dopamine transportertransporter
DutasterideSynaptic vesicular amine transportertransporter
DutasterideSerum albumincarrier
DutasterideAlpha-1-acid glycoprotein 1carrier
DutasterideCytochrome P450 3A5enzyme
EconazoleCytochrome P450 19A1enzyme
EconazoleCytochrome P450 2E1enzyme
EconazoleCytochrome P450 3A4enzyme
EconazoleCytochrome P450 51target
EconazoleNuclear receptor subfamily 1 group I member 2target
RabeprazolePotassium-transporting ATPase alpha chain 1target
RabeprazoleCytochrome P450 3A4enzyme
RabeprazoleCytochrome P450 2C19enzyme
RabeprazoleATP-binding cassette sub-family G member 2transporter
RabeprazoleCytochrome P450 1A1enzyme
RabeprazoleCytochrome P450 1A2enzyme
RabeprazoleCytochrome P450 2C9enzyme
RabeprazoleCytochrome P450 2D6enzyme
RabeprazoleCytochrome P450 2C8enzyme
LevofloxacinDNA gyrase subunit Atarget
LevofloxacinDNA topoisomerase 4 subunit Atarget
LevofloxacinCytochrome P450 1A2enzyme
LevofloxacinSolute carrier family 22 member 2transporter
LevofloxacinP-glycoprotein 1transporter
LevofloxacinSolute carrier family 22 member 4transporter
LevofloxacinMultidrug and toxin extrusion protein 1transporter
LevofloxacinMultidrug and toxin extrusion protein 2transporter
LevofloxacinCytochrome P450 2C9enzyme
LevofloxacinSerum albumincarrier
LevofloxacinSolute carrier organic anion transporter family member 4C1transporter
LevofloxacinSolute carrier family 22 member 1transporter
LevofloxacinSolute carrier organic anion transporter family member 1A2transporter
DiclofenamideCarbonic anhydrase 1target
DiclofenamideCarbonic anhydrase 4target
DiclofenamideCarbonic anhydrase 2target
DiclofenamideCarbonic anhydrase 7target
DiclofenamideCarbonic anhydrase 3target
DesipramineMuscarinic acetylcholine receptor M1target
DesipramineSodium-dependent noradrenaline transportertarget
DesipramineBeta-2 adrenergic receptortarget
DesipramineMuscarinic acetylcholine receptor M2target
DesipramineSodium-dependent serotonin transportertarget
DesipramineHistamine H1 receptortarget
DesipramineBeta-1 adrenergic receptortarget
DesipramineCytochrome P450 2D6enzyme
DesipramineMuscarinic acetylcholine receptor M3target
DesipramineMuscarinic acetylcholine receptor M4target
DesipramineMuscarinic acetylcholine receptor M5target
DesipramineAlpha-1 adrenergic receptorstarget
Desipramine5-hydroxytryptamine receptor 2Atarget
DesipramineAlpha-1-acid glycoprotein 1carrier
DesipramineCytochrome P450 2B6enzyme
DesipramineCytochrome P450 3A4enzyme
DesipramineSolute carrier family 22 member 2transporter
DesipramineSolute carrier family 22 member 1transporter
DesipramineSolute carrier family 22 member 3transporter
DesipramineSolute carrier family 22 member 5transporter
DesipramineP-glycoprotein 1transporter
DesipramineSolute carrier family 22 member 4transporter
DesipramineCytochrome P450 1A2enzyme
DesipramineCytochrome P450 2E1enzyme
DesipramineSphingomyelin phosphodiesterasetarget
Desipramine5-hydroxytryptamine receptor 1Atarget
Desipramine5-hydroxytryptamine receptor 2Ctarget
DesipramineDopamine D2 receptortarget
DesipramineAlpha-2 adrenergic receptorstarget
GemifloxacinDNA gyrase subunit Atarget
GemifloxacinDNA topoisomerase 4 subunit Atarget
GemifloxacinCytochrome P450 1A2enzyme
BupropionSodium-dependent dopamine transportertarget
BupropionSodium-dependent noradrenaline transportertarget
BupropionCytochrome P450 2B6enzyme
BupropionCytochrome P450 2D6enzyme
BupropionAlpha-1-acid glycoprotein 1carrier
BupropionNeuronal acetylcholine receptor subunit alpha-3target
BupropionCytochrome P450 2C9enzyme
BupropionCytochrome P450 2E1enzyme
BupropionSolute carrier family 22 member 2transporter
Bupropion5-hydroxytryptamine receptor 3Atarget
TrimetrexateDihydrofolate reductasetarget
TrimetrexateDihydrofolate reductaseenzyme
TrimetrexateFolate transporter 1transporter
OfloxacinDNA gyrase subunit Atarget
OfloxacinDNA topoisomerase 4 subunit Atarget
OfloxacinDNA topoisomerase 2-alphatarget
OfloxacinCytochrome P450 1A2enzyme
OfloxacinSolute carrier family 22 member 5transporter
OfloxacinMultidrug resistance-associated protein 1transporter
OfloxacinSolute carrier family 22 member 6transporter
OfloxacinCanalicular multispecific organic anion transporter 1transporter
OfloxacinSolute carrier family 22 member 4transporter
OfloxacinBile salt export pumptransporter
CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
CilostazolCytochrome P450 2C19enzyme
CilostazolCytochrome P450 3A4enzyme
CilostazolCytochrome P450 3A5enzyme
CilostazolCytochrome P450 3A7enzyme
CilostazolCytochrome P450 1A2enzyme
CilostazolCytochrome P450 2D6enzyme
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleCytochrome P450 3A4enzyme
ItraconazoleCytochrome P450 3A5enzyme
ItraconazoleCytochrome P450 3A7enzyme
ItraconazoleCytochrome P450 2B6enzyme
ItraconazoleP-glycoprotein 1transporter
ItraconazoleCytochrome P450 1A1enzyme
ItraconazoleCytochrome P450 2E1enzyme
ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
MoclobemideAmine oxidase [flavin-containing] Atarget
MoclobemideCytochrome P450 2C19enzyme
MoclobemideCytochrome P450 2D6enzyme
MoclobemideAmine oxidase [flavin-containing] Aenzyme
MoclobemideAmine oxidase [flavin-containing] Benzyme
MoclobemideCytochrome P450 2C9enzyme
MoclobemideMonoamine oxidasetarget
MoclobemideAmine oxidase [flavin-containing] Btarget
Kanamycin30S ribosomal protein S12target
Kanamycin16S ribosomal RNAtarget
KanamycinAminoglycoside 2'-N-acetyltransferaseenzyme
KanamycinKanamycin nucleotidyltransferaseenzyme
KanamycinAminoglycoside 3'-phosphotransferaseenzyme
OrphenadrineGlutamate receptor ionotropic, NMDA 1target
OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
OrphenadrineHistamine H1 receptortarget
OrphenadrineCytochrome P450 2B6enzyme
OrphenadrineCytochrome P450 2E1enzyme
OrphenadrineCytochrome P450 3A4enzyme
OrphenadrineSodium-dependent noradrenaline transportertarget
OrphenadrineSodium channel protein type 10 subunit alphatarget
OrphenadrineCytochrome P450 1A2enzyme
OrphenadrineCytochrome P450 2D6enzyme
IdarubicinDNA topoisomerase 2-alphatarget
IdarubicinDNAtarget
IdarubicinMultidrug resistance-associated protein 1transporter
IdarubicinCytochrome P450 2C9enzyme
IdarubicinCytochrome P450 2D6enzyme
ClindamycinCytochrome P450 3A4enzyme
ClindamycinCytochrome P450 3A5enzyme
ClindamycinAlpha-1-acid glycoprotein 1carrier
ClindamycinP-glycoprotein 1transporter
Clindamycin50S ribosomal protein L1target
BrinzolamideCarbonic anhydrase 1target
BrinzolamideCarbonic anhydrase 2target
BrinzolamideCytochrome P450 3A4enzyme
BrinzolamideCarbonic anhydrase 5A, mitochondrialtarget
BrinzolamideCarbonic anhydrase 4target
BrinzolamideCarbonic anhydrase 3target
CaptoprilAngiotensin-converting enzymetarget
CaptoprilSerum albumincarrier
Captopril72 kDa type IV collagenasetarget
CaptoprilMatrix metalloproteinase-9target
CaptoprilP-glycoprotein 1transporter
CaptoprilSolute carrier family 15 member 1transporter
CaptoprilSolute carrier family 22 member 6transporter
CaptoprilLeukotriene A-4 hydrolasetarget
CaptoprilB1 bradykinin receptortarget
MitoxantroneDNA topoisomerase 2-alphatarget
MitoxantroneCytochrome P450 2E1enzyme
MitoxantroneP-glycoprotein 1transporter
MitoxantroneMultidrug resistance-associated protein 1transporter
MitoxantroneATP-binding cassette sub-family G member 2transporter
MitoxantroneDNAtarget
MitoxantroneCytochrome P450 1B1enzyme
MitoxantroneCytochrome P450 3A4enzyme
RidogrelThromboxane-A synthasetarget
RidogrelThromboxane A2 receptortarget
SparfloxacinDNA gyrase subunit Atarget
SparfloxacinDNA topoisomerase 4 subunit Atarget
SparfloxacinDNA topoisomerase 2-alphatarget
SparfloxacinSolute carrier family 22 member 5transporter
SparfloxacinCanalicular multispecific organic anion transporter 1transporter
SparfloxacinP-glycoprotein 1transporter
SparfloxacinCytochrome P450 1A2enzyme
Clarithromycin50S ribosomal protein L10target
ClarithromycinCytochrome P450 3A4enzyme
ClarithromycinCytochrome P450 3A5enzyme
ClarithromycinP-glycoprotein 1transporter
ClarithromycinSolute carrier family 22 member 7transporter
ClarithromycinPotassium voltage-gated channel subfamily H member 2target
ClarithromycinSolute carrier organic anion transporter family member 1B1target
ClarithromycinSolute carrier organic anion transporter family member 1B3target
ClarithromycinBile salt export pumptransporter
ClarithromycinSolute carrier organic anion transporter family member 1B1transporter
ClarithromycinSolute carrier organic anion transporter family member 1B3transporter
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
FinasterideCytochrome P450 3A4enzyme
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
FinasterideCytochrome P450 3A5enzyme
FinasterideCytochrome P450 3A7enzyme
FinasterideSolute carrier family 12 member 5transporter
AnastrozoleCytochrome P450 19A1target
AnastrozoleP-glycoprotein 1transporter
AnastrozoleCytochrome P450 3A4enzyme
AnastrozoleCytochrome P450 3A5enzyme
AnastrozoleCytochrome P450 2C8enzyme
AnastrozoleUDP-glucuronosyltransferase 1-4enzyme
AnastrozoleUDP-glucuronosyltransferase 1-3enzyme
AnastrozoleUDP-glucuronosyltransferase 2B7enzyme
AnastrozoleCytochrome P450 1A2enzyme
AnastrozoleCytochrome P450 2C9enzyme
AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AminophyllineAdenosine receptor A3target
AminophyllineAdenosine receptor A1target
AminophyllineCytochrome P450 1A2enzyme
AminophyllineCytochrome P450 2E1enzyme
AminophyllineCytochrome P450 3A4enzyme
AminophyllineHistone deacetylase 2target
SaquinavirHuman immunodeficiency virus type 1 proteasetarget
SaquinavirCytochrome P450 3A4enzyme
SaquinavirCytochrome P450 3A5enzyme
SaquinavirAlpha-1-acid glycoprotein 1carrier
SaquinavirSerum albumincarrier
SaquinavirCytochrome P450 3A7enzyme
SaquinavirP-glycoprotein 1transporter
SaquinavirSolute carrier family 22 member 1transporter
SaquinavirSolute carrier organic anion transporter family member 1A2transporter
SaquinavirATP-binding cassette sub-family G member 2transporter
SaquinavirSolute carrier organic anion transporter family member 1B1transporter
SaquinavirMultidrug resistance-associated protein 1transporter
SaquinavirCanalicular multispecific organic anion transporter 1transporter
SaquinavirCytochrome P450 2C8enzyme
SaquinavirCytochrome P450 2D6enzyme
SaquinavirSolute carrier organic anion transporter family member 2B1transporter
SaquinavirBile salt export pumptransporter
GemfibrozilPeroxisome proliferator-activated receptor alphatarget
GemfibrozilCytochrome P450 2C9enzyme
GemfibrozilCytochrome P450 2C8enzyme
GemfibrozilCytochrome P450 1A2enzyme
GemfibrozilCytochrome P450 2C19enzyme
GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
GemfibrozilCytochrome P450 3A4enzyme
GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
GemfibrozilSolute carrier organic anion transporter family member 1B1target
GemfibrozilUDP-glucuronosyltransferase 2B7enzyme
GemfibrozilUDP-glucuronosyltransferase 1-9enzyme
GemfibrozilUDP-glucuronosyltransferase 2B4enzyme
GemfibrozilUDP-glucuronosyltransferase 2B17enzyme
GemfibrozilSerum albumincarrier
GemfibrozilSolute carrier family 22 member 8target
GemfibrozilSolute carrier organic anion transporter family member 2B1target
GemfibrozilSolute carrier organic anion transporter family member 1B3target
IsocarboxazidAmine oxidase [flavin-containing] Atarget
IsocarboxazidAmine oxidase [flavin-containing] Btarget
DasatinibTyrosine-protein kinase ABL1target
DasatinibAbelson tyrosine-protein kinase 2target
DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DasatinibTyrosine-protein kinase Fyntarget
DasatinibTyrosine-protein kinase Lcktarget
DasatinibTyrosine-protein kinase Yestarget
DasatinibMast/stem cell growth factor receptor Kittarget
DasatinibPlatelet-derived growth factor receptor betatarget
DasatinibEphrin type-A receptor 2target
DasatinibSignal transducer and activator of transcription 5Btarget
DasatinibCytochrome P450 3A4enzyme
DasatinibP-glycoprotein 1transporter
DasatinibATP-binding cassette sub-family G member 2transporter
DasatinibCytochrome P450 1A1enzyme
DasatinibCytochrome P450 1A2enzyme
DasatinibCytochrome P450 1B1enzyme
DasatinibCytochrome P450 3A5enzyme
DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DasatinibTyrosine-protein kinase BTKtarget
DasatinibNuclear receptor subfamily 4 group A member 3target
DasatinibBreakpoint cluster region proteintarget
DasatinibTyrosine-protein kinase CSKtarget
DasatinibEphrin type-A receptor 5target
DasatinibEphrin type-B receptor 4target
DasatinibTyrosine-protein kinase Fgrtarget
DasatinibTyrosine-protein kinase FRKtarget
DasatinibHeat shock cognate 71 kDa proteintarget
DasatinibTyrosine-protein kinase Lyntarget
DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DasatinibMitogen-activated protein kinase 14target
DasatinibAmidophosphoribosyltransferasetarget
LapatinibEpidermal growth factor receptortarget
LapatinibReceptor tyrosine-protein kinase erbB-2target
LapatinibCytochrome P450 3A4enzyme
LapatinibCytochrome P450 2C8enzyme
LapatinibP-glycoprotein 1transporter
LapatinibAntigen peptide transporter 1transporter
LapatinibCytochrome P450 3A5enzyme
LapatinibCytochrome P450 2C19enzyme
SitagliptinDipeptidyl peptidase 4target
SitagliptinCytochrome P450 3A4enzyme
SitagliptinCytochrome P450 2C8enzyme
SitagliptinP-glycoprotein 1transporter
SitagliptinSolute carrier family 22 member 8transporter
DecitabineDNAtarget
DecitabineDNA (cytosine-5)-methyltransferase 1target
DecitabineDeoxycytidine kinaseenzyme
DecitabineUMP-CMP kinaseenzyme
DecitabineNucleoside diphosphokinaseenzyme
DecitabineCytidine deaminaseenzyme
DecitabineDNA (cytosine-5)-methyltransferase 3Atarget
DecitabineDNA (cytosine-5)-methyltransferase 3Btarget
DecitabineSodium/nucleoside cotransporter 1transporter
PosaconazoleCytochrome P450 3A4enzyme
PosaconazoleP-glycoprotein 1transporter
PosaconazoleCytochrome P450 51target
DarunavirHuman immunodeficiency virus type 1 proteasetarget
DarunavirCytochrome P450 3A4enzyme
DarunavirSolute carrier organic anion transporter family member 1B1transporter
DarunavirP-glycoprotein 1transporter
DarunavirSerum albumincarrier
DarunavirAlpha-1-acid glycoprotein 1carrier
DarunavirCytochrome P450 2D6enzyme
TelbivudineProtein Ptarget
TelbivudineDNAtarget
LumiracoxibProstaglandin G/H synthase 2target
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
LumiracoxibCytochrome P450 1A2enzyme
FosamprenavirHuman immunodeficiency virus type 1 proteasetarget
FosamprenavirCytochrome P450 3A4enzyme
CilazaprilAngiotensin-converting enzymetarget
CilazaprilP-glycoprotein 1transporter
CilazaprilSolute carrier family 15 member 1transporter
CilazaprilSolute carrier family 15 member 2transporter
SpiraprilAngiotensin-converting enzymetarget
SpiraprilSolute carrier family 15 member 1transporter
SpiraprilSolute carrier family 15 member 2transporter
RasagilineApoptosis regulator Bcl-2target
RasagilineAmine oxidase [flavin-containing] Btarget
RasagilineCytochrome P450 1A2enzyme
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
MibefradilCytochrome P450 3A4enzyme
MibefradilCytochrome P450 1A2enzyme
MibefradilCytochrome P450 2D6enzyme
MibefradilCytochrome P450 3A5enzyme
MibefradilCytochrome P450 3A7enzyme
MibefradilP-glycoprotein 1transporter
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
MibefradilCytochrome P450 11B1, mitochondrialenzyme
MibefradilCytochrome P450 11B2, mitochondrialenzyme
DigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DigitoxinSerum albumincarrier
DigitoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DigitoxinCytochrome P450 3A4enzyme
DigitoxinSolute carrier organic anion transporter family member 1A2transporter
DigitoxinSolute carrier organic anion transporter family member 4C1transporter
DigitoxinP-glycoprotein 1transporter
Magnesium salicylateSerum albumincarrier
Magnesium salicylateProstaglandin G/H synthase 1target
Magnesium salicylateProstaglandin G/H synthase 2target
NeostigmineAcetylcholinesterasetarget
NeostigmineCholinesteraseenzyme
TemafloxacinDNA gyrase subunit Atarget
TemafloxacinDNA topoisomerase 4 subunit Atarget
TemafloxacinCytochrome P450 1A2enzyme
AmrinoneTumor necrosis factortarget
AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 4target
AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 3target
CilastatinDipeptidase 1target
CilastatinSolute carrier family 22 member 6transporter
CilastatinSolute carrier family 22 member 8transporter
LopinavirHuman immunodeficiency virus type 1 proteasetarget
LopinavirCytochrome P450 3A4enzyme
LopinavirCytochrome P450 2D6enzyme
LopinavirCytochrome P450 2C19enzyme
LopinavirP-glycoprotein 1transporter
LopinavirCytochrome P450 2B6enzyme
LopinavirCytochrome P450 2C9enzyme
LopinavirCytochrome P450 3A Subfamilyenzyme
LopinavirSolute carrier organic anion transporter family member 1B1transporter
LopinavirSolute carrier organic anion transporter family member 1B3transporter
LopinavirBile salt export pumptransporter
LopinavirCytochrome P450 1A2enzyme
LopinavirAlpha-1-acid glycoprotein 1carrier
LopinavirSerum albumincarrier
TazobactamBeta-lactamase TEMtarget
TazobactamSolute carrier family 22 member 6transporter
TazobactamSolute carrier family 22 member 8transporter
TazobactamBeta-lactamase Ohio-1target
TazobactamBeta-lactamase SHV-1target
HydroxychloroquineDNAtarget
HydroxychloroquineToll-like receptor 7target
HydroxychloroquineToll-like receptor 9target
HydroxychloroquineCytochrome P450 2D6enzyme
HydroxychloroquineP-glycoprotein 1transporter
HydroxychloroquineSerum albumincarrier
Hydroxychloroquinealpha1-acid glycoproteincarrier
HydroxychloroquineCytochrome P450 3A4enzyme
HydroxychloroquineSolute carrier organic anion transporter family member 1A2transporter
HydroxychloroquineAngiotensin-converting enzyme 2target
HydroxychloroquineCytochrome P450 2C8enzyme
PargylineAmine oxidase [flavin-containing] Btarget
PargylineAmine oxidase [flavin-containing] Atarget
Lincomycin50S ribosomal protein L10target
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
GenisteinEstrogen receptor betatarget
GenisteinDNA topoisomerase 2-alphatarget
GenisteinProtein-tyrosine kinase 2-betatarget
GenisteinP-glycoprotein 1transporter
GenisteinMultidrug resistance-associated protein 1transporter
GenisteinATP-binding cassette sub-family G member 2transporter
GenisteinCytochrome P450 1A2enzyme
GenisteinNuclear receptor coactivator 1target
GenisteinEstrogen receptor alphatarget
GenisteinNuclear receptor coactivator 2target
GenisteinTransthyretincarrier
GenisteinSteroid hormone receptor ERR2target
GenisteinSteroid hormone receptor ERR1target
GenisteinNuclear receptor subfamily 1 group I member 2target
GenisteinRAC-alpha serine/threonine-protein kinasetarget
GenisteinG-protein coupled estrogen receptor 1target
GenisteinCytochrome P450 1B1target
GenisteinSex hormone-binding globulintarget
GenisteinCytochrome P450 1A1enzyme
GenisteinSolute carrier organic anion transporter family member 1B1transporter
GenisteinSolute carrier organic anion transporter family member 2B1transporter
GenisteinCytochrome P450 2C8enzyme
GenisteinCytochrome P450 2C9enzyme
GenisteinCytochrome P450 3A1enzyme
GenisteinCytochrome P450 3A2enzyme
GenisteinCytochrome P450 3A4enzyme
ChymostatinPeptide amidasetarget
N,N-dimethylarginineNitric oxide synthase, inducibletarget
N,N-dimethylarginineNitric oxide synthase, endothelialtarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
CastanospermineGlucan 1,3-beta-glucosidasetarget
7-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
RolipramcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
RolipramcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
StaurosporineTyrosine-protein kinase Lcktarget
StaurosporineSerine/threonine-protein kinase pim-1target
StaurosporineTyrosine-protein kinase ITK/TSKtarget
StaurosporineTyrosine-protein kinase SYKtarget
StaurosporineMAP kinase-activated protein kinase 2target
StaurosporineGlycogen synthase kinase-3 betatarget
StaurosporineTyrosine-protein kinase CSKtarget
StaurosporineCyclin-dependent kinase 2target
StaurosporinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
Staurosporine3-phosphoinositide-dependent protein kinase 1target
StaurosporineProtein kinase C theta typetarget
StaurosporineTyrosine-protein kinase ZAP-70target
StaurosporineP-glycoprotein 1transporter
StaurosporineMuscarinic acetylcholine receptor M1target
AlrestatinAldose reductasetarget
GabaculineOrnithine aminotransferase, mitochondrialtarget
GabaculineGlutamate-1-semialdehyde 2,1-aminomutasetarget
Aminooxyacetic acidSerine--pyruvate aminotransferasetarget
3,5-DinitrocatecholCatechol O-methyltransferasetarget
DaidzinAldehyde dehydrogenase, mitochondrialtarget
DaidzinATP-binding cassette sub-family G member 2transporter
OlomoucineCyclin-dependent kinase 2target
OlomoucineCyclin-dependent kinase 5target
OlomoucineCyclin-dependent kinase 1target
OlomoucineMitogen-activated protein kinase 1target
K-252aHepatocyte growth factor receptortarget
K-252aDual specificity mitogen-activated protein kinase kinase 1target
7-NitroindazoleNitric oxide synthase, endothelialtarget
7-NitroindazoleNitric oxide synthase, inducibletarget
IlomastatLethal factortarget
IlomastatDisintegrin and metalloproteinase domain-containing protein 28target
IlomastatAggrecan core proteintarget
5'-S-methyl-5'-thioadenosineModification methylase RsrItarget
5'-S-methyl-5'-thioadenosineS-methyl-5'-thioadenosine phosphorylasetarget
1,10-PhenanthrolineMethyl-accepting chemotaxis protein IItarget
1,10-PhenanthrolineMetallo-beta-lactamase L1target
TolrestatAldose reductasetarget
TolrestatAlcohol dehydrogenase [NADP(+)]target
TolrestatAldo-keto reductase family 1 member B10target
GeldanamycinHeat shock protein HSP 90-alphatarget
GeldanamycinHeat shock protein HSP 90-betatarget
GeldanamycinEndoplasmintarget
Trehalose-6-PhosphateHTH-type transcriptional regulator TreRtarget
VorinostatHistone deacetylase 1target
VorinostatHistone deacetylase 2target
VorinostatHistone deacetylase 3target
VorinostatHistone deacetylase 6target
VorinostatHistone deacetylase 8target
VorinostatAcetoin utilization proteintarget
PhosphoramidonNeprilysintarget
PhosphoramidonKell blood group glycoproteintarget
LY-294002Serine/threonine-protein kinase pim-1target
LY-294002Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
Fusidic acidChloramphenicol acetyltransferase 3target
Fusidic acidChloramphenicol acetyltransferasetarget
Fusidic acidBile salt export pumptransporter
Fusidic acidCanalicular multispecific organic anion transporter 1transporter
Fusidic acidElongation factor Gtarget
Fusidic acidCytochrome P450 2D6enzyme
Fusidic acidCytochrome P450 3A4enzyme
Fusidic acidUDP-glucuronosyltransferase 1-1enzyme
Fusidic acidATP-binding cassette sub-family G member 2transporter
Fusidic acidSolute carrier organic anion transporter family member 1B1transporter
ResveratrolTransthyretincarrier
ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
ResveratrolProstaglandin G/H synthase 1target
ResveratrolCasein kinase II subunit alphatarget
ResveratrolProstaglandin G/H synthase 2target
ResveratrolNAD-dependent protein deacetylase sirtuin-1target
ResveratrolCytochrome P450 1A1enzyme
ResveratrolCytochrome P450 3A4enzyme
ResveratrolCytochrome P450 1A2enzyme
ResveratrolCytochrome P450 1B1enzyme
ResveratrolArachidonate 15-lipoxygenasetarget
ResveratrolArachidonate 5-lipoxygenasetarget
ResveratrolAryl hydrocarbon receptortarget
ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
ResveratrolIntegrin alpha-5target
ResveratrolIntegrin beta-3target
ResveratrolSerum albumincarrier
ResveratrolAmyloid beta A4 proteintarget
ResveratrolAlpha-synucleintarget
ResveratrolEstrogen receptor alphatarget
ResveratrolMelatonin receptor type 1Atarget
ResveratrolMelatonin receptor type 1Btarget
ResveratrolC-type lectin domain family 14 member Atarget
ResveratrolNuclear receptor subfamily 1 group I member 2target
ResveratrolNuclear receptor subfamily 1 group I member 3target
ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
ResveratrolCarbonyl reductase [NADPH] 1target
ResveratrolPeroxisome proliferator-activated receptor alphatarget
ResveratrolPeroxisome proliferator-activated receptor gammatarget
ResveratrolRAC-alpha serine/threonine-protein kinasetarget
ResveratrolFar upstream element-binding protein 2target
ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
KifunensineAlpha-mannosidase 2target
KifunensineEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
KifunensineMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
PyrazoleAlcohol dehydrogenase 1Ctarget
PyrazoleEstrogen receptor alphatarget
PyrazoleEstrogen receptor betatarget
Phosphonoacetic AcidAlkaline phosphatasetarget
N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-ProlineCathepsin Btarget
Calyculin ASerine/threonine-protein phosphatase PP1-gamma catalytic subunittarget
DazoxibenThromboxane-A synthasetarget
3-MethoxybenzamidePoly [ADP-ribose] polymerase 1target
BenzamidineUrokinase-type plasminogen activatortarget
BenzamidineTrypsin-1target
BenzamidineCasein kinase II subunit alphatarget
BenzamidineKallikrein-6target
BenzamidineTrypsin-2target
BenzamidineTrypsin-3target
BenzamidineCopper transport protein ATOX1target
BenzamidineEnoyl-CoA delta isomerase 1, mitochondrialtarget
BenzamidineTrypsintarget
BenzamidineSuppressor of tumorigenicity 14 proteintarget
BenzamidineKallikrein-1target
DuvoglustatCyclomaltodextrin glucanotransferasetarget
DuvoglustatBeta-glucosidase Atarget
DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DuvoglustatXylose isomerasetarget
ImidazoleMonomeric sarcosine oxidasetarget
ImidazoleNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
ImidazoleMyoglobintarget
ImidazoleNitric oxide synthase, inducibletarget
ImidazoleAdenylate kinase 2, mitochondrialtarget
ImidazoleSerine/threonine-protein kinase pim-1target
ImidazoleIsopentenyl-diphosphate Delta-isomerasetarget
ImidazoleAlpha,alpha-trehalose-phosphate synthase [UDP-forming]target
ImidazoleLeukotriene A-4 hydrolasetarget
ImidazoleGephyrintarget
ImidazoleAcyl carrier proteintarget
ImidazoleSensor protein FixLtarget
ImidazoleCytochrome ctarget
ImidazoleCircadian clock protein KaiBtarget
ImidazoleHistidinol dehydrogenasetarget
ImidazoleAcyl-CoA thioesterase Itarget
ImidazoleA/G-specific adenine glycosylasetarget
ImidazoleYopE regulatortarget
ImidazoleUnconventional myosin-Ietarget
ImidazoleMeiotic recombination protein DMC1/LIM15 homologtarget
ImidazoleGuanine deaminasetarget
ImidazoleEndo-1,4-beta-xylanase Atarget
ImidazoleBacterial hemoglobintarget
ImidazoleMolybdenum cofactor biosynthesis protein Btarget
ImidazoleUracil-DNA glycosylase inhibitortarget
ImidazoleRecombination protein RecRtarget
EnalkirenRenintarget
UbenimexBacterial leucyl aminopeptidasetarget
UbenimexLeukotriene A-4 hydrolasetarget
UbenimexSolute carrier family 15 member 1transporter
UbenimexSolute carrier family 15 member 2transporter
Sparfosic acidAspartate carbamoyltransferase catalytic chaintarget
Sparfosic acidCAD proteintarget
AlvocidibGlycogen phosphorylase, muscle formtarget
AlvocidibCyclin-dependent kinase 7target
AlvocidibCyclin-dependent kinase 5target
AlvocidibCyclin-dependent kinase 9target
AlvocidibCyclin-dependent kinase 1target
AlvocidibCyclin-dependent kinase 6target
AlvocidibEpidermal growth factor receptortarget
AlvocidibCyclin-dependent kinase 4target
AlvocidibCyclin-dependent kinase 8target
AlvocidibCyclin-dependent kinase 2target
AlvocidibATP-binding cassette sub-family G member 2transporter
AlvocidibGlycogen phosphorylase, brain formtarget
AlvocidibGlycogen phosphorylase, liver formtarget
AlvocidibUDP-glucuronosyltransferase 1-1enzyme
2-(4-Chlorophenyl)-5-QuinoxalinecarboxamidePoly [ADP-ribose] polymerase 1target
EniluracilDihydropyrimidine dehydrogenase [NADP(+)]target
EniluracilAldehyde oxidasetarget
EniluracilXanthine dehydrogenase/oxidasetarget
PhencyclidineGlutamate receptor ionotropic, NMDA 3Atarget
PhencyclidineSigma non-opioid intracellular receptor 1target
PhencyclidineCytochrome P450 2B6enzyme
Picric acidPentaerythritol tetranitrate reductasetarget
RadicicolHeat shock protein HSP 90-betatarget
RadicicolEndoplasmintarget
RadicicolDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialtarget
Radicicol[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrialtarget
RadicicolVirulence sensor histidine kinase PhoQtarget
Palmitic AcidRhodopsintarget
Palmitic AcidSerum albumincarrier
Palmitic AcidPalmitoyl-protein thioesterase 1target
Palmitic AcidMyelin P2 proteintarget
Palmitic AcidFatty acid-binding protein, adipocytecarrier
Palmitic AcidFatty acid-binding protein, epidermalcarrier
Palmitic AcidGlycodelintarget
Palmitic AcidFatty acid-binding protein, heartcarrier
Palmitic AcidHepatocyte nuclear factor 4-gammatarget
Palmitic AcidLipid binding proteintarget
Palmitic AcidCytochrome P450 2C8target
Palmitic AcidTrafficking protein particle complex subunit 3target
Palmitic AcidFatty acid-binding protein TM_1468target
Palmitic AcidFatty acid-binding protein, intestinalcarrier
Palmitic AcidAlpha-lactalbumintarget
Palmitic AcidPeroxisome proliferator-activated receptor alphatarget
CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
BatimastatNeutrophil collagenasetarget
BatimastatMacrophage metalloelastasetarget
BatimastatMatrix metalloproteinase-16target
BatimastatDisintegrin and metalloproteinase domain-containing protein 28target
BatimastatA disintegrin and metalloproteinase with thrombospondin motifs 5target
S-HexylglutathioneLactoylglutathione lyasetarget
S-HexylglutathioneGlutathione S-transferase Mu 4target
S-HexylglutathioneGlutathione S-transferase Ptarget
S-HexylglutathioneGlutathione S-transferasetarget
S-HexylglutathioneGlutathione S-transferase A1target
S-HexylglutathioneGlutathione S-transferase theta-2target
S-HexylglutathioneGlutathione S-transferase A1enzyme
NitroarginineNitric oxide synthase, endothelialtarget
NitroarginineNitric oxide synthase, braintarget
Dipicolinic acid4-hydroxy-tetrahydrodipicolinate reductasetarget
Dipicolinic acid4-hydroxy-tetrahydrodipicolinate reductasetarget
Maleic AcidAspartate aminotransferasetarget
Maleic AcidTrypanothione reductasetarget
Maleic AcidAspartate aminotransferasetarget
Maleic AcidAromatic-amino-acid aminotransferasetarget
Maleic AcidAspartate aminotransferase, cytoplasmictarget
3,4-DichloroisocoumarinComplement factor Dtarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideCalmodulintarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin C, slow skeletal and cardiac musclestarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin I, cardiac muscletarget
2,4-DinitrophenolPentaerythritol tetranitrate reductasetarget
Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
GlyphosateCytochrome P450 19A1target
GlyphosateSerum albumincarrier
Niflumic acidPhospholipase A2target
Niflumic acidChloride channel protein ClC-Katarget
Niflumic acidMonocarboxylate transporter 2transporter
Niflumic acidMonocarboxylate transporter 1transporter
Niflumic acidProstaglandin G/H synthase 2target
Niflumic acidProstaglandin G/H synthase 1target
Niflumic acidCytosolic phospholipase A2target
Niflumic acidUDP-glucuronosyltransferase 1-9target
Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
FleroxacinDNA topoisomerase 2-alphatarget
FleroxacinDNA gyrase subunit Atarget
FleroxacinDNA topoisomerase 4 subunit Atarget
5-iodotubercidinCasein kinase I isoform gamma-2target
5-iodotubercidinSerine/threonine-protein kinase haspintarget
5-iodotubercidinMitogen-activated protein kinase 3target
AllosamidinChitinase Btarget
AllosamidinChitinase Atarget
MetoprineHistamine N-methyltransferasetarget
CamptothecinDNA topoisomerase 1target
CamptothecinP-glycoprotein 1transporter
CamptothecinATP-binding cassette sub-family G member 2transporter
CamptothecinSerum albumincarrier
NimesulideProstaglandin G/H synthase 2target
NimesulideGroup IIE secretory phospholipase A2target
NimesulideLactotransferrintarget
NimesulideCytochrome P450 3A4enzyme
IproniazidAmine oxidase [flavin-containing] Benzyme
IproniazidCytochrome P450 2D6enzyme
IproniazidCytochrome P450 2C9enzyme
IproniazidAmine oxidase [flavin-containing] Aenzyme
NialamideAmine oxidase [flavin-containing] Btarget
NialamideAmine oxidase [flavin-containing] Atarget
NialamideCatechol O-methyltransferasetarget
CediranibVascular endothelial growth factor receptor 2target
Huperzine AAcetylcholinesterasetarget
HalofuginoneCollagen alpha-1(I) chaintarget
Halofuginone72 kDa type IV collagenasetarget
VildagliptinDipeptidyl peptidase 4target
VogliboseMaltase-glucoamylase, intestinaltarget
VatalanibVascular endothelial growth factor receptor 1target
VatalanibVascular endothelial growth factor receptor 2target
VatalanibVascular endothelial growth factor receptor 3target
EnoximonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
XimelagatranProthrombintarget
XimelagatranCytochrome P450 2C9enzyme
StannsoporfinHeme oxygenase 1target
StannsoporfinHeme oxygenase 2target
PermethrinCytochrome P450 2B6enzyme
PermethrinSodium channel protein type 1 subunit alphatarget
PermethrinEstrogen receptor alphatarget
PermethrinNuclear receptor subfamily 1 group I member 2target
RanpirnaseDNAtarget
BelinostatHistone deacetylasetarget
BelinostatCytochrome P450 1A2enzyme
BelinostatUDP-glucuronosyltransferase 1-4enzyme
BelinostatCytochrome P450 2C8enzyme
BelinostatCytochrome P450 2C9enzyme
BelinostatP-glycoprotein 1transporter
BelinostatCytochrome P450 3A4enzyme
AmonafideDNA topoisomerase 2-alphatarget
AmonafideDNA topoisomerase 2-betatarget
TetrathiomolybdateAmyloid beta A4 proteintarget
ElafinNeutrophil elastasetarget
ElafinMyeloblastintarget
ElafinMyeloperoxidaseenzyme
OxypurinolXanthine dehydrogenase/oxidasetarget
EcabetNADPH oxidase organizer 1target
EcabetUrease subunit alphatarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IbudilastcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DexlansoprazolePotassium-transporting ATPase alpha chain 1target
DexlansoprazoleCytochrome P450 2C19enzyme
DexlansoprazoleCytochrome P450 3A4enzyme
DexlansoprazolePotassium-transporting ATPase subunit betatarget
DexlansoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
Varespladib methylPhospholipase A2, membrane associatedtarget
Varespladib methylGroup 10 secretory phospholipase A2target
AbirateroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
AbirateroneSerum albumincarrier
AbirateroneAlpha-1-acid glycoprotein 1carrier
AbirateroneCytochrome P450 3A4enzyme
AbirateroneBile salt sulfotransferaseenzyme
AbirateroneMultidrug resistance-associated protein 1transporter
AbirateroneCytochrome P450 2D6enzyme
AbirateroneCytochrome P450 2C8enzyme
AbirateroneCytochrome P450 1A2enzyme
AbirateroneCytochrome P450 2C19enzyme
AbirateroneCytochrome P450 2C9enzyme
RubitecanDNA topoisomerase 1target
GarenoxacinCytochrome P450 1A2enzyme
SeliciclibCyclin-dependent kinase 1target
SeliciclibCyclin-dependent kinase 2target
SeliciclibMitogen-activated protein kinase 3target
SeliciclibMitogen-activated protein kinase 1target
SeliciclibCyclin-dependent kinase 7target
SeliciclibCyclin-dependent kinase 9target
SeliciclibCasein kinase I isoform epsilontarget
SeliciclibProstaglandin G/H synthase 2enzyme
AlogliptinDipeptidyl peptidase 4target
AlogliptinCytochrome P450 3A4enzyme
AlogliptinCytochrome P450 2D6enzyme
RivaroxabanCoagulation factor Xtarget
RivaroxabanCytochrome P450 3A4enzyme
RivaroxabanCytochrome P450 2J2enzyme
RivaroxabanP-glycoprotein 1transporter
RivaroxabanCytochrome P450 3A5enzyme
RivaroxabanATP-binding cassette sub-family G member 2transporter
EflornithineOrnithine decarboxylasetarget
ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
ExisulindcGMP-specific 3',5'-cyclic phosphodiesterasetarget
ExisulindcGMP-dependent 3',5'-cyclic phosphodiesterasetarget
ExisulindGlutathione S-transferase Ptarget
ExisulindAldose reductasetarget
ExisulindAldo-keto reductase family 1 member B10target
UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
UdenafilCytochrome P450 3A4enzyme
UdenafilCytochrome P450 3A5enzyme
SimeprevirNS3 proteasetarget
SimeprevirSerum albumincarrier
SimeprevirCytochrome P450 1A2enzyme
SimeprevirP-glycoprotein 1transporter
SimeprevirSolute carrier organic anion transporter family member 1B1transporter
SimeprevirSolute carrier organic anion transporter family member 1B3transporter
SimeprevirCytochrome P450 3A4enzyme
SimeprevirCanalicular multispecific organic anion transporter 1transporter
SimeprevirATP-binding cassette sub-family G member 2transporter
SimeprevirSolute carrier organic anion transporter family member 2B1transporter
SimeprevirSodium/bile acid cotransportertransporter
SimeprevirBile salt export pumptransporter
DarapladibCytosolic phospholipase A2target
SaxagliptinDipeptidyl peptidase 4target
SaxagliptinCytochrome P450 3A4enzyme
SaxagliptinCytochrome P450 3A5enzyme
SaxagliptinMultidrug resistance-associated protein 1transporter
SaxagliptinSolute carrier organic anion transporter family member 4C1transporter
SaxagliptinSolute carrier family 22 member 8transporter
IclaprimDihydrofolate reductasetarget
IdraparinuxCoagulation factor Xtarget
EtravirineCytochrome P450 2C19enzyme
EtravirineCytochrome P450 2C9enzyme
EtravirineCytochrome P450 3A4enzyme
EtravirineGag-Pol polyproteintarget
EtravirineGag-Pol polyproteintarget
EtravirineP-glycoprotein 1transporter
EtravirineMultidrug resistance protein 3transporter
TezacitabineRibonucleoside-diphosphate reductase large subunittarget
TezacitabineThymidine phosphorylaseenzyme
SemaxanibVascular endothelial growth factor receptor 2target
SemaxanibProstaglandin G/H synthase 2enzyme
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
PanobinostatCytochrome P450 2D6enzyme
PanobinostatCytochrome P450 3A4enzyme
PanobinostatP-glycoprotein 1transporter
PanobinostatHistone deacetylasetarget
ApixabanCoagulation factor Xtarget
ApixabanCytochrome P450 3A4enzyme
ApixabanCytochrome P450 1A2enzyme
ApixabanCytochrome P450 2C8enzyme
ApixabanCytochrome P450 2C9enzyme
ApixabanCytochrome P450 2C19enzyme
ApixabanCytochrome P450 2J2enzyme
ApixabanP-glycoprotein 1transporter
ApixabanATP-binding cassette sub-family G member 2transporter
ApixabanCytochrome P450 3A5enzyme
PeramivirNeuraminidasetarget
PeramivirNeuraminidasetarget
PeramivirNeuraminidasetarget
AxitinibVascular endothelial growth factor receptor 1target
AxitinibVascular endothelial growth factor receptor 2target
AxitinibVascular endothelial growth factor receptor 3target
AxitinibCytochrome P450 3A4enzyme
AxitinibCytochrome P450 3A5enzyme
AxitinibCytochrome P450 1A2enzyme
AxitinibCytochrome P450 2C19enzyme
AxitinibUDP-glucuronosyltransferase 1-1enzyme
AxitinibP-glycoprotein 1transporter
AxitinibSolute carrier organic anion transporter family member 1B1transporter
OtamixabanCoagulation factor Xtarget
AprotininTrypsin-1target
AprotininChymotrypsinogen Btarget
AprotininPlasminogentarget
AprotininKallikrein-1target
AprotininCholinesteraseenzyme
Mevastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
MevastatinLiver carboxylesterase 1enzyme
Dabigatran etexilateProthrombintarget
Dabigatran etexilateP-glycoprotein 1transporter
Dabigatran etexilateLiver carboxylesterase 1enzyme
Dabigatran etexilateCocaine esteraseenzyme
Dabigatran etexilateUDP-glucuronosyltransferase 1-9enzyme
Dabigatran etexilateUDP-glucuronosyltransferase 2B7enzyme
Dabigatran etexilateUDP-glucuronosyltransferase 2B15enzyme
Dabigatran etexilateRibosyldihydronicotinamide dehydrogenase [quinone]enzyme
IobenguaneSodium-dependent noradrenaline transportertransporter
beta-NaphthoflavoneCytochrome P450 1A2enzyme
beta-NaphthoflavoneEstrogen receptor alphatarget
beta-NaphthoflavoneSteroid hormone receptor ERR1target
beta-NaphthoflavoneCOUP transcription factor 1target
beta-NaphthoflavoneAryl hydrocarbon receptortarget
beta-NaphthoflavoneCytochrome P450 1B1target
Bafilomycin A1V-type proton ATPase catalytic subunit Atarget
BesifloxacinDNA topoisomerase 4 subunit Atarget
BesifloxacinDNA topoisomerase 4 subunit Atarget
BesifloxacinDNA gyrase subunit Atarget
BesifloxacinDNA gyrase subunit Atarget
BesifloxacinCytochrome P450 1A2enzyme
PlicamycinDNAtarget
RaltegravirUDP-glucuronosyltransferase 1-1enzyme
RaltegravirIntegrasetarget
Viomycin16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyAtarget
VeliparibPoly [ADP-ribose] polymerase 1target
VeliparibPoly [ADP-ribose] polymerase 2target
4-(2-Aminoethyl)Benzenesulfonyl FluorideGlyceraldehyde-3-phosphate dehydrogenasetarget
4-(2-Aminoethyl)Benzenesulfonyl FluorideV-type proton ATPase subunit B, brain isoformtarget
Brefeldin ACytohesin-2target
Brefeldin AADP-ribosylation factor 1target
Brefeldin ACytochrome P450 3A4enzyme
Anisomycin60S ribosomal protein L10-liketarget
Anisomycin60S ribosomal protein L13atarget
Anisomycin60S ribosomal protein L23target
Anisomycin60S ribosomal protein L15target
Anisomycin60S ribosomal protein L19target
Anisomycin60S ribosomal protein L23atarget
AnisomycinProbable ribosome biogenesis protein RLP24target
Anisomycin60S ribosomal protein L26-like 1target
Anisomycin60S ribosomal protein L8target
Anisomycin60S ribosomal protein L37target
Anisomycin60S ribosomal protein L3target
Anisomycin60S ribosomal protein L11target
AnisomycinNHP2-like protein 1target
Z-Val-Ala-Asp fluoromethyl ketoneCaspase-1target
3-isobutyl-1-methyl-7H-xanthinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
3-isobutyl-1-methyl-7H-xanthinecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
3-isobutyl-1-methyl-7H-xanthineHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7Atarget
3-isobutyl-1-methyl-7H-xanthinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
3-isobutyl-1-methyl-7H-xanthineHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9Atarget
3-isobutyl-1-methyl-7H-xanthineHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8Atarget
3-isobutyl-1-methyl-7H-xanthinecGMP-dependent 3',5'-cyclic phosphodiesterasetarget
3-isobutyl-1-methyl-7H-xanthineRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
5-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase catalytic subunit alphatarget
5-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase inhibitor alphatarget
Puromycin60S ribosomal protein L10-liketarget
Puromycin60S ribosomal protein L13atarget
Puromycin60S ribosomal protein L23target
Puromycin60S ribosomal protein L15target
Puromycin60S ribosomal protein L19target
Puromycin60S ribosomal protein L23atarget
PuromycinProbable ribosome biogenesis protein RLP24target
Puromycin60S ribosomal protein L26-like 1target
Puromycin60S ribosomal protein L8target
Puromycin60S ribosomal protein L37target
Puromycin60S ribosomal protein L3target
Puromycin60S ribosomal protein L11target
PuromycinLeucyl/phenylalanyl-tRNA--protein transferasetarget
ParecoxibLactotransferrintarget
ParecoxibProstaglandin G/H synthase 2target
ParecoxibCytochrome P450 3A4enzyme
ParecoxibCytochrome P450 2C9enzyme
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolinePhenylethanolamine N-methyltransferasetarget
ThiorphanNeprilysintarget
TemocaprilSolute carrier family 15 member 1transporter
TemocaprilSolute carrier organic anion transporter family member 1A2transporter
TemocaprilAngiotensin-converting enzymetarget
PitavastatinSolute carrier organic anion transporter family member 1B1transporter
PitavastatinSolute carrier organic anion transporter family member 1B3transporter
PitavastatinUDP-glucuronosyltransferase 2B7enzyme
PitavastatinUDP-glucuronosyltransferase 1-3enzyme
PitavastatinCytochrome P450 2C9enzyme
PitavastatinCytochrome P450 2C8enzyme
Pitavastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PitavastatinSolute carrier organic anion transporter family member 2B1transporter
PitavastatinSodium/bile acid cotransportertransporter
PitavastatinATP-binding cassette sub-family G member 2transporter
PitavastatinP-glycoprotein 1transporter
PitavastatinCanalicular multispecific organic anion transporter 1transporter
PitavastatinSerum albumincarrier
PitavastatinAlpha-1-acid glycoprotein 1carrier
PitavastatinBile salt export pumptransporter
PitavastatinIntegrin alpha-Ltarget
RilpivirineCytochrome P450 3A4enzyme
RilpivirineReverse transcriptase/RNaseHtarget
RilpivirineNuclear receptor subfamily 1 group I member 2target
RilpivirineCytochrome P450 2C19enzyme
RilpivirineCytochrome P450 2B6enzyme
RilpivirineP-glycoprotein 1transporter
RilpivirineATP-binding cassette sub-family G member 2transporter
RilpivirineSolute carrier organic anion transporter family member 1B1transporter
RilpivirineSolute carrier organic anion transporter family member 1B3transporter
RilpivirineSerum albumincarrier
RilpivirineCytochrome P450 2D6enzyme
CrizotinibCytochrome P450 3A4enzyme
CrizotinibCytochrome P450 3A5enzyme
CrizotinibP-glycoprotein 1transporter
CrizotinibALK tyrosine kinase receptortarget
CrizotinibHepatocyte growth factor receptortarget
CrizotinibCytochrome P450 2B6enzyme
CrizotinibCytochrome P450 3A Subfamilyenzyme
AminopterinProton-coupled folate transportertransporter
AminopterinDihydrofolate reductaseenzyme
LinagliptinDipeptidyl peptidase 4target
LinagliptinCytochrome P450 3A4enzyme
LinagliptinP-glycoprotein 1transporter
LinagliptinSolute carrier family 22 member 1transporter
LinagliptinSolute carrier family 22 member 2transporter
LinagliptinSolute carrier family 22 member 3transporter
TofacitinibNon-receptor tyrosine-protein kinase TYK2target
TofacitinibCytochrome P450 3A4enzyme
TofacitinibCytochrome P450 2C19enzyme
TofacitinibTyrosine-protein kinase JAK2target
TofacitinibTyrosine-protein kinase JAK1target
TofacitinibTyrosine-protein kinase JAK3target
TofacitinibSerum albumincarrier
PonatinibTyrosine-protein kinase ABL1target
PonatinibBreakpoint cluster region proteintarget
PonatinibMast/stem cell growth factor receptor Kittarget
PonatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
PonatinibAngiopoietin-1 receptortarget
PonatinibReceptor-type tyrosine-protein kinase FLT3target
PonatinibCytochrome P450 3A4enzyme
PonatinibCytochrome P450 2C8enzyme
PonatinibCytochrome P450 2D6enzyme
PonatinibCytochrome P450 3A5enzyme
PonatinibP-glycoprotein 1transporter
PonatinibATP-binding cassette sub-family G member 2transporter
PonatinibFibroblast growth factor receptor 1target
PonatinibFibroblast growth factor receptor 2target
PonatinibFibroblast growth factor receptor 3target
PonatinibFibroblast growth factor receptor 4target
PonatinibTyrosine-protein kinase Lcktarget
PonatinibProto-oncogene tyrosine-protein kinase Srctarget
PonatinibTyrosine-protein kinase Lyntarget
PonatinibVascular endothelial growth factor receptor 2target
PonatinibPlatelet-derived growth factor receptor alphatarget
FormestaneCytochrome P450 3A4enzyme
TrametinibCytochrome P450 2C8enzyme
TrametinibCytochrome P450 3A4enzyme
TrametinibDual specificity mitogen-activated protein kinase kinase 1target
TrametinibDual specificity mitogen-activated protein kinase kinase 2target
DabrafenibCytochrome P450 3A4enzyme
DabrafenibCytochrome P450 2C8enzyme
DabrafenibP-glycoprotein 1transporter
DabrafenibATP-binding cassette sub-family G member 2transporter
DabrafenibSolute carrier organic anion transporter family member 1B1transporter
DabrafenibSolute carrier organic anion transporter family member 1B3transporter
DabrafenibSolute carrier family 22 member 6transporter
DabrafenibSolute carrier family 22 member 8transporter
DabrafenibSerine/threonine-protein kinase B-raftarget
DabrafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DabrafenibSerine/threonine-protein kinase SIK1target
DabrafenibSerine/threonine-protein kinase Nek11target
DabrafenibLIM domain kinase 1target
DabrafenibCytochrome P450 2B6enzyme
DabrafenibCytochrome P450 2C9enzyme
DolutegravirUDP-glucuronosyltransferase 1-1enzyme
DolutegravirCytochrome P450 3A Subfamilyenzyme
DolutegravirIntegrasetarget
DolutegravirSolute carrier family 22 member 2transporter
DolutegravirUDP-glucuronosyltransferase 1-3enzyme
DolutegravirUDP-glucuronosyltransferase 1-9enzyme
DolutegravirATP-binding cassette sub-family G member 2transporter
DolutegravirSolute carrier family 22 member 6transporter
DolutegravirSolute carrier family 22 member 8transporter
DolutegravirP-glycoprotein 1transporter
FlumequineCytochrome P450 1A2enzyme
EliglustatCeramide glucosyltransferasetarget
EliglustatCytochrome P450 2D6enzyme
EliglustatCytochrome P450 3A4enzyme
EliglustatP-glycoprotein 1transporter
IdelalisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
IdelalisibATP-binding cassette sub-family G member 2transporter
IdelalisibP-glycoprotein 1transporter
IdelalisibAldehyde oxidaseenzyme
IdelalisibCytochrome P450 2C8enzyme
IdelalisibCytochrome P450 2C19enzyme
IdelalisibCytochrome P450 2B6enzyme
IdelalisibCytochrome P450 3A4enzyme
IdelalisibSolute carrier organic anion transporter family member 1B1transporter
IdelalisibSolute carrier organic anion transporter family member 1B3transporter
IdelalisibCytochrome P450 3A5enzyme
IdelalisibCytochrome P450 3A43enzyme
IdelalisibCytochrome P450 3A7enzyme
IdelalisibUDP-glucuronosyltransferase 1-4enzyme
AvibactamCanalicular multispecific organic anion transporter 1transporter
AvibactamSolute carrier family 22 member 8transporter
AvibactamBeta-lactamase TEMtarget
AvibactamBeta-lactamase CTX-Mtarget
AvibactamBeta-lactamasetarget
AvibactamBeta-lactamase SHV-1target
AvibactamBeta-lactamase SHV-2target
AvibactamBeta-lactamase SHV-1target
AvibactamClass D OXA-48 carbapenemasetarget
AvibactamCarbapenem-hydrolyzing beta-lactamase KPCtarget
AvibactamBeta-lactamase CTX-M-15target
AvibactamExtended-spectrum beta-lactamase PER-1target
CeritinibALK tyrosine kinase receptortarget
CeritinibP-glycoprotein 1transporter
CeritinibCytochrome P450 2C9enzyme
CeritinibCytochrome P450 3A4enzyme
CobicistatCytochrome P450 2D6enzyme
CobicistatP-glycoprotein 1transporter
CobicistatATP-binding cassette sub-family G member 2transporter
CobicistatCytochrome P450 3A4enzyme
CobicistatCytochrome P450 3A5enzyme
CobicistatCytochrome P450 3A7enzyme
CobicistatCytochrome P450 3A43enzyme
CobicistatSolute carrier organic anion transporter family member 1B1transporter
CobicistatSolute carrier organic anion transporter family member 1B3transporter
PalbociclibCyclin-dependent kinase 4target
PalbociclibCyclin-dependent kinase 6target
PalbociclibCytochrome P450 3A4enzyme
PalbociclibBile salt sulfotransferaseenzyme
PalbociclibP-glycoprotein 1transporter
PalbociclibATP-binding cassette sub-family G member 2transporter
PalbociclibSerum albumincarrier
PalbociclibSolute carrier family 22 member 1transporter
OlaparibPoly [ADP-ribose] polymerase 1target
OlaparibCytochrome P450 3A4enzyme
OlaparibCytochrome P450 2B6enzyme
OlaparibPoly [ADP-ribose] polymerase 2target
OlaparibPoly [ADP-ribose] polymerase 3target
OlaparibCytochrome P450 3A5enzyme
OlaparibP-glycoprotein 1transporter
OlaparibATP-binding cassette sub-family G member 2transporter
EdoxabanCoagulation factor Xtarget
EdoxabanP-glycoprotein 1transporter
LenvatinibVascular endothelial growth factor receptor 1target
LenvatinibVascular endothelial growth factor receptor 2target
LenvatinibVascular endothelial growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 1target
LenvatinibFibroblast growth factor receptor 2target
LenvatinibFibroblast growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 4target
LenvatinibPlatelet-derived growth factor receptor alphatarget
LenvatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
LenvatinibMast/stem cell growth factor receptor Kittarget
LenvatinibP-glycoprotein 1transporter
LenvatinibATP-binding cassette sub-family G member 2transporter
LenvatinibCytochrome P450 3A4enzyme
LenvatinibAldehyde oxidaseenzyme
LenvatinibCytochrome P450 2C8enzyme
LenvatinibCytochrome P450 2C9enzyme
LenvatinibCytochrome P450 1A2enzyme
LenvatinibCytochrome P450 2B6enzyme
LenvatinibCytochrome P450 2C19enzyme
LenvatinibSolute carrier family 22 member 6transporter
LenvatinibSolute carrier family 22 member 8transporter
LenvatinibSolute carrier family 22 member 2transporter
LenvatinibSolute carrier organic anion transporter family member 1B1transporter
LenvatinibBile salt export pumptransporter
LenvatinibCytochrome P450 2D6enzyme
NintedanibVascular endothelial growth factor receptor 1target
NintedanibVascular endothelial growth factor receptor 2target
NintedanibVascular endothelial growth factor receptor 3target
NintedanibPlatelet-derived growth factor receptor alphatarget
NintedanibPlatelet-derived growth factor receptor betatarget
NintedanibFibroblast growth factor receptor 1target
NintedanibFibroblast growth factor receptor 2target
NintedanibFibroblast growth factor receptor 3target
NintedanibReceptor-type tyrosine-protein kinase FLT3target
NintedanibTyrosine-protein kinase Lcktarget
NintedanibTyrosine-protein kinase Lyntarget
NintedanibProto-oncogene tyrosine-protein kinase Srctarget
NintedanibP-glycoprotein 1transporter
NintedanibCytochrome P450 3A4enzyme
NintedanibSolute carrier family 22 member 1transporter
NintedanibSerum albumincarrier
NintedanibUDP-glucuronosyltransferase 1-1enzyme
NintedanibUDP-glucuronosyltransferase 1-7enzyme
NintedanibUDP-glucuronosyltransferase 1-8enzyme
NintedanibUDP-glucuronosyltransferase 1-10enzyme
NintedanibATP-binding cassette sub-family G member 2transporter
Chlortetracycline16S ribosomal RNAtarget
ChlortetracyclineSerum albumincarrier
Chlortetracycline30S ribosomal protein S3target
Chlortetracycline30S ribosomal protein S8target
Chlortetracycline30S ribosomal protein S19target
Chlortetracycline30S ribosomal protein S14target
Chlortetracycline30S ribosomal protein S7target
Methylene blueGuanylate cyclase soluble subunit alpha-2target
Methylene blueNitric oxide synthase, braintarget
Methylene blueUDP-glucuronosyltransferase 1-4enzyme
Methylene blueUDP-glucuronosyltransferase 1-9enzyme
Methylene blueCytochrome P450 1A2enzyme
Methylene blueCytochrome P450 2B6enzyme
Methylene blueCytochrome P450 2C8enzyme
Methylene blueCytochrome P450 2C9enzyme
Methylene blueCytochrome P450 2C19enzyme
Methylene blueCytochrome P450 3A4enzyme
Methylene blueCytochrome P450 3A5enzyme
Methylene blueSerum albumincarrier
Methylene blueP-glycoprotein 1transporter
Methylene blueSolute carrier family 22 member 2transporter
Methylene blueMultidrug and toxin extrusion protein 2transporter
Methylene blueMultidrug and toxin extrusion protein 1transporter
Methylene blueFlavin reductase (NADPH)enzyme
Methylene blueCytochrome P450 2D6enzyme
PirlindoleAmine oxidase [flavin-containing] Atarget
Pirlindole5-hydroxytryptamine receptor 1Atarget
PirlindoleAlpha-2A adrenergic receptortarget
PirlindoleAmine oxidase [flavin-containing] Aenzyme
ToloxatoneAmine oxidase [flavin-containing] Atarget
ToloxatoneAmine oxidase [flavin-containing] Aenzyme
DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme
TrapidilPlatelet-derived growth factor receptor betatarget
TrapidilCyclic nucleotide phosphodiesterasetarget
SulbactamBeta-lactamasetarget
OsimertinibEpidermal growth factor receptortarget
OsimertinibP-glycoprotein 1transporter
OsimertinibATP-binding cassette sub-family G member 2transporter
OsimertinibCytochrome P450 3A4enzyme
OsimertinibCytochrome P450 1A2enzyme
MersalylAlkaline phosphatase, tissue-nonspecific isozymetarget
MersalylAquaporin-1target
MersalylMonocarboxylate transporter 1target
MersalylInter-alpha-trypsin inhibitor heavy chain H1enzyme
MersalylPhosphoenolpyruvate carboxykinase, cytosolic [GTP]enzyme
EnalaprilatAngiotensin-converting enzymetarget
EnalaprilatB1 bradykinin receptortarget
DichlorvosSerum albumincarrier
DichlorvosSerotransferrintarget
DichlorvosCholinesterasetarget
MonensinP-glycoprotein 1transporter
PimobendanCytochrome P450 1A2enzyme
Antithrombin III humanAntithrombin-IIItarget
CandoxatrilatNeprilysintarget
OpicaponeCytochrome P450 2C19enzyme
OpicaponeCytochrome P450 2C8enzyme
OpicaponeCatechol O-methyltransferasetarget
CurcuminPeroxisome proliferator-activated receptor gammatarget
CurcuminVitamin D3 receptortarget
CurcuminMultidrug resistance-associated protein 5target
CurcuminCarbonyl reductase [NADPH] 1target
CurcuminGlutathione S-transferase Ptarget
CurcuminCytochrome P450 2C9enzyme
CurcuminCytochrome P450 3A4enzyme
CurcuminCytochrome P450 2B6enzyme
CurcuminCytochrome P450 1A2enzyme
CurcuminCytochrome P450 2D6enzyme
CurcuminGlutathione S-transferase A1enzyme
CurcuminGlutathione S-transferase Mu 1enzyme
CurcuminGlutathione S-transferase Penzyme
CurcuminP-glycoprotein 1transporter
TalazoparibPoly [ADP-ribose] polymerase 1target
TalazoparibPoly [ADP-ribose] polymerase 2target
TalazoparibP-glycoprotein 1transporter
TalazoparibATP-binding cassette sub-family G member 2transporter
PazufloxacinCytochrome P450 1A2enzyme
MirodenafilCytochrome P450 3A Subfamilyenzyme
NiraparibPoly [ADP-ribose] polymerase 1target
NiraparibPoly [ADP-ribose] polymerase 2target
NiraparibCarboxylesteraseenzyme
NiraparibBeta-glucuronidaseenzyme
SaracatinibCytochrome P450 3A4enzyme
MocetinostatHistone deacetylase 1target
MocetinostatHistone deacetylase 3target
MocetinostatHistone deacetylase 2target
PrulifloxacinCytochrome P450 1A2enzyme
6-O-benzylguanineCytochrome P450 3A4enzyme
VinpocetineCytochrome P450 3A4enzyme
CantharidinAryl hydrocarbon receptortarget
CantharidinSkin epithelial cellstarget
RucaparibPoly [ADP-ribose] polymerase 1target
RucaparibPoly [ADP-ribose] polymerase 2target
RucaparibPoly [ADP-ribose] polymerase 3target
RucaparibCytochrome P450 2D6enzyme
RucaparibCytochrome P450 1A2enzyme
RucaparibCytochrome P450 3A4enzyme
RucaparibP-glycoprotein 1transporter
RucaparibATP-binding cassette sub-family G member 2transporter
RucaparibMultidrug and toxin extrusion protein 1transporter
RucaparibMultidrug and toxin extrusion protein 2transporter
RucaparibSolute carrier family 22 member 1transporter
RucaparibMultidrug resistance-associated protein 4transporter
RucaparibSolute carrier organic anion transporter family member 1B1transporter
RucaparibSolute carrier organic anion transporter family member 1B3transporter
RucaparibSolute carrier family 22 member 6transporter
RucaparibSolute carrier family 22 member 8transporter
RucaparibCytochrome P450 3A5enzyme
RucaparibCytochrome P450 3A7enzyme
RucaparibCytochrome P450 3A43enzyme
RucaparibCytochrome P450 2C19enzyme
RucaparibCytochrome P450 2C9enzyme
RucaparibCytochrome P450 2C8enzyme
RucaparibUDP-glucuronosyltransferase 1-1enzyme
RelebactamSolute carrier family 22 member 8transporter
RelebactamSolute carrier family 22 member 11transporter
RelebactamMultidrug and toxin extrusion protein 1transporter
RelebactamMultidrug and toxin extrusion protein 2transporter
RelebactamBeta-lactamase TEMtarget
RelebactamBeta-lactamase SHV-1target
RelebactamBeta-lactamase CTX-Mtarget
RelebactamBeta-lactamase (KPC-2)target
RelebactamBeta-lactamasetarget
NitroaspirinProstaglandin G/H synthase 1target
AbexinostatHistone deacetylase 1target
PiperineNuclear receptor subfamily 1 group I member 2target
PiperineCytochrome P450 3A4enzyme
PiperineP-glycoprotein 1transporter
NafamostatIntercellular adhesion molecule 1target
NafamostatTrypsin-1target
NafamostatKallikrein-1target
NafamostatProthrombintarget
NafamostatCoagulation factor Xtarget
NafamostatCoagulation factor XIItarget
NafamostatSolute carrier family 22 member 1transporter
NafamostatSolute carrier family 22 member 2transporter
Phenethyl IsothiocyanateActin, aortic smooth muscletarget
Phenethyl IsothiocyanateActin, cytoplasmic 1target
Phenethyl IsothiocyanateATP synthase subunit beta, mitochondrialtarget
Phenethyl IsothiocyanateATP synthase subunit e, mitochondrialtarget
Phenethyl IsothiocyanateATP synthase subunit g, mitochondrialtarget
Phenethyl IsothiocyanateCytochrome b5 type Btarget
Phenethyl IsothiocyanateDiablo homolog, mitochondrialtarget
Phenethyl IsothiocyanateF-box only protein 41target
Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ftarget
Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ktarget
Phenethyl IsothiocyanateHeat shock 70 kDa protein 4target
Phenethyl IsothiocyanateHeat shock protein beta-1target
Phenethyl Isothiocyanate10 kDa heat shock protein, mitochondrialtarget
Phenethyl IsothiocyanateHeat shock protein 105 kDatarget
Phenethyl IsothiocyanateNADH-ubiquinone oxidoreductase chain 1target
Phenethyl IsothiocyanateNuclear migration protein nudCtarget
Phenethyl IsothiocyanatePappalysin-1target
Phenethyl IsothiocyanateProteasome subunit alpha type-3target
Phenethyl Isothiocyanate26S protease regulatory subunit 6Atarget
Phenethyl IsothiocyanateRan-specific GTPase-activating proteintarget
Phenethyl IsothiocyanateProtein S100-A10target
Phenethyl IsothiocyanateSplicing factor 3A subunit 3target
Phenethyl IsothiocyanateSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1target
Phenethyl IsothiocyanateSuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrialtarget
Phenethyl IsothiocyanateTumor protein D54target
Phenethyl IsothiocyanateTropomyosin alpha-1 chaintarget
Phenethyl IsothiocyanateTropomyosin alpha-3 chaintarget
Phenethyl IsothiocyanateTropomyosin alpha-4 chaintarget
Phenethyl IsothiocyanateTubulin alpha-1A chaintarget
Phenethyl IsothiocyanateTubulin alpha-3C/D chaintarget
Phenethyl IsothiocyanateTubulin alpha-4A chaintarget
Phenethyl IsothiocyanateTubulin beta-1 chaintarget
Phenethyl IsothiocyanateTubulin beta-2A chaintarget
Phenethyl IsothiocyanateTubulin beta-3 chaintarget
Phenethyl IsothiocyanateTubulin beta-4B chaintarget
Phenethyl IsothiocyanateThioredoxintarget
Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase isozyme L1target
Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase 14target
Phenethyl IsothiocyanateTransitional endoplasmic reticulum ATPasetarget
Phenethyl IsothiocyanateVimentintarget
Phenethyl Isothiocyanate14-3-3 protein beta/alphatarget
Phenethyl Isothiocyanate14-3-3 protein epsilontarget
Phenethyl Isothiocyanate14-3-3 protein etatarget
Phenethyl Isothiocyanate14-3-3 protein thetatarget
Phenethyl Isothiocyanate14-3-3 protein zeta/deltatarget
LometrexolDihydrofolate reductasetarget
BenserazideAromatic-L-amino-acid decarboxylasetarget
GabexateTrypsin-1enzyme
GabexateComplement C1s subcomponentenzyme
GabexateComplement C1r subcomponentenzyme
GabexatePlasma kallikreintarget
GabexateProthrombintarget
GabexatePlasminogentarget
HypericinSerum albumincarrier
HypericinGlutathione S-transferase A1target
HypericinGlutathione S-transferase Ptarget
TalarozoleCytochrome P450 26A1target
ZofenoprilAngiotensin-converting enzymetarget
RheinOxysterols receptor LXR-alphatarget
RheinOxysterols receptor LXR-betatarget
RheinArylamine N-acetyltransferasetarget
RheinArachidonate 5-lipoxygenasetarget
RheinCytochrome P450 1A2enzyme
RheinCytochrome P450 3A Subfamilyenzyme
RheinCytochrome P450 2E1enzyme
RheinCytochrome P450 2C9enzyme
RheinCytochrome P450 2D6enzyme
SitafloxacinCytochrome P450 1A2enzyme
FlurithromycinCytochrome P450 3A4enzyme
Oxolinic acidCytochrome P450 1A2enzyme
CamostatTrypsin-1target
CamostatTransmembrane protease serine 2target
CamostatSuppressor of tumorigenicity 14 proteintarget
CamostatCholecystokinintarget
DexrabeprazoleCytochrome P450 2C19enzyme
RufloxacinCytochrome P450 1A2enzyme
Calcium levulinateCalmodulintarget
Calcium levulinateCalsequestrin-1target
Calcium levulinateCalretinintarget
AdefovirDNA polymerase/reverse transcriptasetarget
HarmalineHistamine N-methyltransferasetarget
BrofaromineAmine oxidase [flavin-containing] Atarget
IniparibPoly [ADP-ribose] polymerase 1target
ClinafloxacinCytochrome P450 1A2enzyme
ClinafloxacinCytochrome P450 2C19enzyme
ClinafloxacinCytochrome P450 2D6enzyme
ClinafloxacinCytochrome P450 2C9enzyme
FurafyllineCytochrome P450 1A2enzyme
ABT-341Dipeptidyl peptidase 4target
WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
WortmanninSerine/threonine-protein kinase PLK1target
WortmanninPhosphatidylinositol 3-kinase regulatory subunit alphatarget
WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
BasifunginInositol phosphorylceramide synthasetarget
SC-236Cyclooxygenase 2target
SC-236Nuclear factor NF-kappa-B complextarget
NS-398Cyclooxygenase 2target
Concanamycin AP-glycoprotein 1target
Concanamycin AP-glycoprotein 1transporter
TenofovirP-glycoprotein 1transporter
TenofovirSolute carrier family 22 member 6transporter
TenofovirSolute carrier family 22 member 8transporter
TenofovirMultidrug resistance-associated protein 4transporter
TenofovirCytochrome P450 3A4enzyme
TenofovirNucleoside diphosphate kinase Aenzyme
TenofovirNucleoside diphosphate kinase Benzyme
TenofovirAdenylate kinase isoenzyme 1enzyme
TenofovirAdenylate kinase 2, mitochondrialenzyme
TenofovirReverse transcriptase/RNaseHtarget
TenofovirReverse transcriptasetarget
TenofovirDNA polymerasetarget
TenofovirSerum albumincarrier
Lithium carbonateInositol monophosphatase 2target
Lithium carbonateInositol monophosphatase 1target
Lithium carbonateGlycogen synthase kinase-3 betatarget
Lithium carbonateGlutamate receptor 3target
Lithium carbonateAmiloride-sensitive sodium channel subunit alphatransporter
Lithium carbonateAmiloride-sensitive sodium channel subunit betatransporter
Lithium carbonateAmiloride-sensitive sodium channel subunit gammatransporter
Magnesium levulinateSodium/potassium-transporting ATPase subunit alpha-1target
AcifluorfenProtoporphyrinogen oxidasetarget
AcifluorfenProtoporphyrinogen oxidasetarget
acetylleucyl-leucyl-norleucinalProteasome subunit alpha type-7target
Cholesterol sulfateNuclear receptor ROR-alphatarget
ZenarestatAldose reductasetarget
S-EthylisothioureaNitric oxide synthase oxygenasetarget
S-EthylisothioureaNitric oxide synthase, inducibletarget
S-EthylisothioureaNitric oxide synthase, endothelialtarget
Oseltamivir acidNeuraminidasetarget
ZardaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
BrequinarDihydroorotate dehydrogenase (quinone), mitochondrialtarget
PiritreximDihydrofolate reductasetarget
ClorgilineAmine oxidase [flavin-containing] Atarget
Meglutol3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PimagedineNitric oxide synthase, inducibletarget
PimagedineAldose reductasetarget
PimagedineMetalloproteinase inhibitor 3target
PimagedineSolute carrier family 22 member 2transporter
7-ethyl-10-hydroxycamptothecinDNA topoisomerase 1target
7-ethyl-10-hydroxycamptothecinCytochrome P450 3A4enzyme
EmodinCasein kinase II subunit alphatarget
EmodinPutative ketoacyl reductasetarget
Emodin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
EmodinAryl hydrocarbon receptortarget
FasudilcAMP-dependent protein kinase inhibitor alphatarget
FasudilcAMP-dependent protein kinase catalytic subunit alphatarget
FasudilRho-associated protein kinase 1target
FasudilRho-associated protein kinase 2target
EmivirineGag-Pol polyproteintarget
LapachoneRetinol-binding protein 3target
EbselenBifunctional epoxide hydrolase 2target
Methoxy arachidonyl fluorophosphonateFatty-acid amide hydrolase 1target
CidofovirDNA polymerase catalytic subunittarget
CidofovirSolute carrier family 22 member 6transporter
CidofovirThymidine phosphorylaseenzyme
FamciclovirDNA polymerase catalytic subunittarget
FamciclovirAldehyde oxidaseenzyme
CaspofunginSolute carrier family 22 member 1transporter
CaspofunginP-glycoprotein 1transporter
CaspofunginSolute carrier family 22 member 6transporter
CaspofunginSolute carrier organic anion transporter family member 1B1transporter
CaspofunginSolute carrier organic anion transporter family member 1B3transporter
CaspofunginCytochrome P450 3A4enzyme
Caspofungin1,3-beta-glucan synthase component FKS1target
Tigecycline30S ribosomal protein S9target
Tigecycline16S ribosomal RNAtarget
Tigecycline30S ribosomal protein S14target
Tigecycline30S ribosomal protein S13target
Tigecycline30S ribosomal protein S19target
Tigecycline30S ribosomal protein S12target
FondaparinuxAntithrombin-IIItarget
FondaparinuxCoagulation factor Xtarget
OxaprozinProstaglandin G/H synthase 2target
OxaprozinProstaglandin G/H synthase 1target
FomepizoleAlcohol dehydrogenase 1Atarget
FomepizoleAlcohol dehydrogenase 1Btarget
FomepizoleAlcohol dehydrogenase 1Ctarget
FomepizoleCatalasetarget
FomepizoleCytochrome P450 2E1enzyme
FomepizoleCytochrome P450 2A6enzyme
SunitinibPlatelet-derived growth factor receptor betatarget
SunitinibVascular endothelial growth factor receptor 1target
SunitinibVascular endothelial growth factor receptor 2target
SunitinibVascular endothelial growth factor receptor 3target
SunitinibMast/stem cell growth factor receptor Kittarget
SunitinibReceptor-type tyrosine-protein kinase FLT3target
SunitinibMacrophage colony-stimulating factor 1 receptortarget
SunitinibPlatelet-derived growth factor receptor alphatarget
SunitinibCytochrome P450 3A4enzyme
SunitinibCytochrome P450 3A5enzyme
SunitinibCytochrome P450 3A7enzyme
SunitinibMultidrug resistance-associated protein 4transporter
SunitinibP-glycoprotein 1transporter
SunitinibCanalicular multispecific organic anion transporter 1transporter
SunitinibATP-binding cassette sub-family G member 2transporter
TopiroxostatXanthine dehydrogenase/oxidasetarget
TopiroxostatATP-binding cassette sub-family G member 2transporter
TopiroxostatSerum albumincarrier
TopiroxostatAlpha-1-acid glycoprotein 1carrier
TopiroxostatCytochrome P450 2C8enzyme
TopiroxostatCytochrome P450 2C9enzyme
TopiroxostatCytochrome P450 1A1enzyme
TopiroxostatCytochrome P450 3A4enzyme
TopiroxostatCytochrome P450 2C19enzyme
TopiroxostatSolute carrier family 22 member 8transporter
TopiroxostatSolute carrier family 22 member 6transporter
TopiroxostatUDP-glucuronosyltransferase 1-9enzyme
D-EritadenineAdenosylhomocysteinasetarget
MonastrolKinesin-like protein KIF11target
2,5-di-tert-butylhydroquinoneSarcoplasmic/endoplasmic reticulum calcium ATPase 1target
LicofeloneArachidonate 5-lipoxygenasetarget
LicofeloneProstaglandin G/H synthase 2target
LicofeloneGroup IIE secretory phospholipase A2target
LicofeloneCytochrome P450 2C9enzyme
LicofeloneCytochrome P450 2C8enzyme
LicofeloneCytochrome P450 2J2enzyme
LicofeloneUDP-glucuronosyltransferase 1-3enzyme
MyxothiazolCytochrome b-c1 complex subunit 1, mitochondrialtarget
Omacetaxine mepesuccinate50S ribosomal protein L2target
Omacetaxine mepesuccinate60S ribosomal protein L3target
PhenserineAcetylcholinesterasetarget
PhenserineCholinesterasetarget
PhenserineAmyloid beta A4 proteintarget
RupintrivirGenome polyproteintarget
RanirestatAldose reductasetarget
PelitinibEpidermal growth factor receptortarget
ArylacenamideHCG20471, isoform CRA_ctarget
AV-412Epidermal growth factor receptortarget
AV-412Receptor tyrosine-protein kinase erbB-2target
IndisulamCytochrome P450 2C9enzyme
IndisulamCytochrome P450 3A4enzyme
IndisulamCytochrome P450 2E1enzyme
IndisulamCytochrome P450 2D6enzyme
Human C1-esterase inhibitorComplement C1r subcomponenttarget
Human C1-esterase inhibitorComplement C1s subcomponenttarget
Human C1-esterase inhibitorPlasma kallikreintarget
Human C1-esterase inhibitorCoagulation factor XIItarget
Human C1-esterase inhibitorProthrombintarget
Human C1-esterase inhibitorCoagulation factor XItarget
Human C1-esterase inhibitorTissue-type plasminogen activatortarget
LonafarnibProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphatarget
LonafarnibP-glycoprotein 1transporter
LonafarnibProtein farnesyltransferase subunit betatarget
LonafarnibCytochrome P450 3A Subfamilyenzyme
LonafarnibCytochrome P450 2C8enzyme
LonafarnibCytochrome P450 2C19enzyme
LonafarnibCytochrome P450 1A2enzyme
LonafarnibCytochrome P450 2A6enzyme
LonafarnibCytochrome P450 2C9enzyme
LonafarnibCytochrome P450 2E1enzyme
LonafarnibSolute carrier organic anion transporter family member 1B1transporter
LonafarnibSolute carrier organic anion transporter family member 1B3transporter
LonafarnibATP-binding cassette sub-family G member 2transporter
LonafarnibCytochrome P450 3A4enzyme
LonafarnibCytochrome P450 3A5enzyme
LonafarnibCanalicular multispecific organic anion transporter 1transporter
CetilistatPancreatic triacylglycerol lipasetarget
MafenideCarbonic anhydrase 6target
CapravirineCytochrome P450 3A4enzyme
CapravirineGag-Pol polyproteintarget
CapravirineCytochrome P450 2C8enzyme
CapravirineCytochrome P450 2C9enzyme
CapravirineCytochrome P450 2C19enzyme
VemurafenibSerum albumincarrier
VemurafenibAlpha-1-acid glycoprotein 1carrier
VemurafenibCytochrome P450 1A2enzyme
VemurafenibCytochrome P450 2D6enzyme
VemurafenibCytochrome P450 3A4enzyme
VemurafenibSerine/threonine-protein kinase B-raftarget
VemurafenibMultidrug resistance-associated protein 1transporter
VemurafenibATP-binding cassette sub-family G member 2transporter
VemurafenibCytochrome P450 2C9enzyme
VemurafenibCytochrome P450 2C8enzyme
VemurafenibCytochrome P450 2B6enzyme
VemurafenibP-glycoprotein 1transporter
AfatinibEpidermal growth factor receptortarget
AfatinibReceptor tyrosine-protein kinase erbB-2target
AfatinibReceptor tyrosine-protein kinase erbB-4target
AfatinibP-glycoprotein 1transporter
AfatinibATP-binding cassette sub-family G member 2transporter
FinafloxacinDNA gyrase subunit Atarget
FinafloxacinDNA topoisomerase 4 subunit Atarget
FinafloxacinDNA topoisomerase 2-alphatarget
DesirudinCarboxypeptidase A1enzyme
AsunaprevirGenome polyproteintarget
AsunaprevirCytochrome P450 3A4enzyme
AsunaprevirCytochrome P450 3A5enzyme
AsunaprevirCytochrome P450 2A6enzyme
AsunaprevirCytochrome P450 2B6enzyme
AsunaprevirCytochrome P450 2C9enzyme
AsunaprevirCytochrome P450 2C19enzyme
AsunaprevirCytochrome P450 2D6enzyme
AsunaprevirSolute carrier organic anion transporter family member 1B1transporter
AsunaprevirSolute carrier organic anion transporter family member 1B3transporter
AsunaprevirSolute carrier organic anion transporter family member 2B1transporter
AsunaprevirP-glycoprotein 1transporter
MK-1775Wee1-like protein kinasetarget
TosedostatPuromycin-sensitive aminopeptidasetarget
TosedostatLeukotriene A-4 hydrolasetarget
Bempedoic acidATP-citrate synthasetarget
Bempedoic acidVery long-chain acyl-CoA synthetaseenzyme
Bempedoic acidSolute carrier organic anion transporter family member 1B1transporter
Bempedoic acidCanalicular multispecific organic anion transporter 2transporter
Bempedoic acidSolute carrier organic anion transporter family member 1B3transporter
Bempedoic acidUDP-glucuronosyltransferase 2B7enzyme
Bempedoic acidAcetyl-coenzyme A synthetase, cytoplasmicenzyme
Bempedoic acidNUAK family SNF1-like kinase 2enzyme
TesevatinibPro-epidermal growth factortarget
TesevatinibEphrin type-B receptor 4target
TesevatinibReceptor tyrosine-protein kinase erbB-2target
EntrectinibCytochrome P450 3A4enzyme
EntrectinibP-glycoprotein 1transporter
EntrectinibHigh affinity nerve growth factor receptortarget
EntrectinibBDNF/NT-3 growth factors receptortarget
EntrectinibNT-3 growth factor receptortarget
EntrectinibProto-oncogene tyrosine-protein kinase ROStarget
EntrectinibTyrosine-protein kinase JAK2target
EntrectinibActivated CDC42 kinase 1target
VaborbactamBeta-lactamasetarget
VaborbactamCarbapenem-hydrolyzing beta-lactamase KPCtarget
VaborbactamBeta-lactamase (KPC-2)target
VaborbactamBeta-lactamase CTX-Mtarget
VaborbactamBeta-lactamase (blaSHV)target
VaborbactamBeta-lactamase SHV-1target
VaborbactamBeta-lactamase TEMtarget
VaborbactamBeta-lactamase (MIR-1)target
VaborbactamBeta-lactamasetarget
ObatoclaxApoptosis regulator Bcl-2target
BetrixabanP-glycoprotein 1transporter
BetrixabanCoagulation factor Xtarget
BetrixabanPotassium voltage-gated channel subfamily H member 2transporter
BetrixabanProthrombinenzyme
Baloxavir marboxilATP-binding cassette sub-family B member 5transporter
Baloxavir marboxilUDP-glucuronosyltransferase 1-3enzyme
Baloxavir marboxilCytochrome P450 3A4enzyme
Baloxavir marboxilPolymerase acidic proteintarget
IvosidenibIsocitrate dehydrogenase [NADP] cytoplasmictarget
IvosidenibCytochrome P450 3A4enzyme
IvosidenibCytochrome P450 2B6enzyme
IvosidenibCytochrome P450 2C9enzyme
IvosidenibCytochrome P450 2C8enzyme
IvosidenibSolute carrier family 22 member 8transporter
IvosidenibP-glycoprotein 1transporter
CPI-1205Histone-lysine N-methyltransferase EZH2target
ZanubrutinibCytochrome P450 3A4enzyme
ZanubrutinibP-glycoprotein 1transporter
ZanubrutinibCytochrome P450 2B6enzyme
ZanubrutinibTyrosine-protein kinase BTKtarget
ZanubrutinibEpidermal growth factor receptortarget
ZanubrutinibReceptor tyrosine-protein kinase erbB-2target
ZanubrutinibReceptor tyrosine-protein kinase erbB-4target
ZanubrutinibTyrosine-protein kinase ITK/TSKtarget
ZanubrutinibCytoplasmic tyrosine-protein kinase BMXtarget
ZanubrutinibTyrosine-protein kinase JAK2target
ZanubrutinibTyrosine-protein kinase Tectarget
ZanubrutinibTyrosine-protein kinase Blktarget
ZanubrutinibTyrosine-protein kinase JAK3target
ZanubrutinibProtein-tyrosine kinase 6target
ZanubrutinibTyrosine-protein kinase Fgrtarget
ZanubrutinibTyrosine-protein kinase FRKtarget
ZanubrutinibTyrosine-protein kinase Lcktarget
ZanubrutinibTyrosine-protein kinase TXKtarget
ZanubrutinibCytochrome P450 3A Subfamilyenzyme
UpadacitinibTyrosine-protein kinase JAK1target
UpadacitinibCytochrome P450 3A4enzyme
UpadacitinibCytochrome P450 2D6enzyme
UpadacitinibP-glycoprotein 1transporter
UpadacitinibATP-binding cassette sub-family G member 2transporter
UpadacitinibSolute carrier organic anion transporter family member 1B1transporter
AbivertinibEpidermal growth factor receptortarget
AbivertinibTyrosine-protein kinase BTKtarget
CilazaprilatAngiotensin-converting enzymetarget
p-Hydroxymercuribenzoic acidCarbonic anhydrase 2target
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamideStromelysin-1target
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamideStromelysin-1target
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideHistone deacetylase 8target
2-deoxy-2,3-dehydro-N-acetylneuraminic acidHemagglutinin-neuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidSialidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidNeuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidHemagglutinin-neuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidSialidase-2target
ThiocitrullineNitric oxide synthase, inducibletarget
N(G)-IminoethylornithineNitric oxide synthase, endothelialtarget
R-82913Gag-Pol polyproteintarget
R-82913Gag-Pol polyproteintarget
H-89cAMP-dependent protein kinase catalytic subunit alphatarget
H-89cAMP-dependent protein kinase inhibitor alphatarget
H-89Serine/threonine-protein kinase haspintarget
ZopolrestatAldo-keto reductase family 1 member B10target
ZopolrestatAldose reductasetarget
CGS-27023Macrophage metalloelastasetarget
CGS-27023Interstitial collagenasetarget
Bisindolylmaleimide VIII3-phosphoinositide-dependent protein kinase 1target
Bisindolylmaleimide VIIIMyotonin-protein kinasetarget
CP-320626Glycogen phosphorylase, muscle formtarget
Trichostatin AHistone deacetylase 8target
Trichostatin AAcetoin utilization proteintarget
Trichostatin AHistone deacetylase 7target
GW-813893Prothrombintarget
GW-813893Coagulation factor Xtarget
Y-27632cAMP-dependent protein kinase catalytic subunit alphatarget
Y-27632cAMP-dependent protein kinase inhibitor alphatarget
Y-27632Rho-associated protein kinase 1target
Y-27632Rho-associated protein kinase 2target
Bisindolylmaleimide ISerine/threonine-protein kinase pim-1target
Bisindolylmaleimide I3-phosphoinositide-dependent protein kinase 1target
Bisindolylmaleimide IProtein kinase C iota typetarget
5-BenzylacyclouridineUridine phosphorylasetarget
5-BenzylacyclouridineUridine phosphorylase 1target
HarmineAmine oxidase [flavin-containing] Atarget
DichlororibofuranosylbenzimidazoleCasein kinase II subunit alphatarget
DorsomorphinActivin receptor type-1target
DorsomorphinPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
Adenosine 5'-methylenediphosphateDNAtarget
Adenosine 5'-methylenediphosphateRibose-phosphate pyrophosphokinasetarget
Adenosine 5'-methylenediphosphateMutT/nudix family proteintarget
Adenosine 5'-methylenediphosphateProtein UshAtarget
t-ButylhydroquinoneHemagglutinintarget
t-ButylhydroquinoneHemagglutinintarget
MethyldopaAlpha-2A adrenergic receptortarget
MethyldopaCatechol O-methyltransferaseenzyme
MethyldopaSolute carrier family 15 member 1transporter
MethyldopaAromatic-L-amino-acid decarboxylasetarget
(Rp)-cAMPScAMP-dependent protein kinase type I-alpha regulatory subunittarget
Vigabatrin4-aminobutyrate aminotransferase, mitochondrialtarget
VigabatrinProton-coupled amino acid transporter 1transporter
VigabatrinCytochrome P450 2C9enzyme
Zinc protoporphyrinCytochrome ctarget