Anticoagulants

Name
Anticoagulants
Accession Number
DBCAT000007  (DBCAT003243)
Description

Agents that prevent clotting.

Drugs
DrugDrug Description
BivalirudinA direct thrombin inhibitor used to treat heparin-induced thrombocytopenia and to prevent thrombosis during percutaneous coronary intervention.
AbciximabA monoclonal anti-glycoprotein IIb/IIIa receptor antibody used to prevent thrombosis during percutaneous coronary intervention.
DicoumarolFor decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis.
ArgatrobanA synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
ArdeparinFor prevention of deep vein thrombosis, which may result in pulmonary embolism, following knee surgery.
PhenindioneFor the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
FondaparinuxAn anticoagulant used to prevent venous thromboembolism, to treat deep vein thrombosis, and to improve survival following myocardial infarction.
WarfarinA vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
Pentosan polysulfateA sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis.
PhenprocoumonUsed for the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation...
Edetic acidA chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.
HeparinAn anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
EnoxaparinA low molecular weight heparin used for the prophylaxis of deep vein thrombosis and ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin.
AcenocoumarolAn anticoagulant drug used in the prevention of thromboembolic diseases in infarction and transient ischemic attacks, as well as management of deep vein thrombosis and myocardial infarction.
XimelagatranFor the treatment of acute deep vein thrombosis.
AncrodAn anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country.
RivaroxabanA factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
SulodexideSulodexide has been used clinically for the prophylaxis and treatment of vascular diseases with increased risk of thrombosis, including intermittent claudication, peripheral arterial occlusive disease and post-myocardial infarc-tion. Also investigated...
IdraparinuxInvestigated for use/treatment in thrombosis, venous thromboembolism, strokes, heart disease, and atrial fibrillation.
ApixabanAn anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.
OtamixabanInvestigated for use/treatment in thrombosis.
Dabigatran etexilateAn anticoagulant used for the prevention of venous thromboembolic events or stroke in patients with recent elective hip or knee replacement surgery and atrial fibrillation.
DanaparoidA heparinoid with anticoagulant and antithrombotic activities used for the treatment of acute episode of Heparin-Induced Thrombocytopenia (HIT), and for prophylaxis in patients with a history of HIT.
DalteparinA low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction.
Ferulic acidNot Available
Ethyl biscoumacetateEthyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
NadroparinA low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction.
EdoxabanA novel oral anticoagulant used for reducing the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF).
DextranA low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures.
ReviparinBy the FDA, reviparin is indicated for the treatment of deep vein which may lead to pulmonary embolism in pediatric patients. It is also indicated for the long-term treatment of...
CertoparinUsed in the prevention and treatment of venous thromboembolism (deep vein thrombosis and pulmonary embolism) and in the treatment of myocardial infarction.
DesirudinIndicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery.
ProtocatechualdehydeAlso known as protocatechuic aldehyde, protocatechualdehyde is a naturally-occuring phenolic aldehyde that is found in barley, green cavendish bananas, grapevine leaves and root of the herb S. miltiorrhiza . Protocatechualdehyde...
Protein CA medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis.
Antithrombin III humanAn alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency.
LetaxabanLetaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.
DarexabanDarexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
NafamostatUsed as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement...
GabexateNo approved indication.
TroxerutinTroxerutin has been used in trials studying the treatment of Chronic Venous Insufficiency.
FluindioneFluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. Fluindione has been investigated for...
Protein S humanA medication used for emergency reversal of coagulation factor deficiency in vitamin K antagonist therapy.
MelagatranNot Annotated
Potassium citrateAn agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
Sodium citrateAn ingredient used for the anticoagulation of whole blood as part of automated apheresis procedures.
TenecteplaseA modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli.
Drotrecogin alfaA form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII.
DefibrotideA mixture of single-stranded oligonucleotides used in the treatment of severe hepatic veno-occlusive disease with renal or pulmonary dysfunction following hematopoietic stem-cell transplantation.
TinzaparinA low molecular weight heparin used for the treatment of acute symptomatic deep vein thrombosis with or without pulmonary embolism when administered in conjunction with warfarin.
BrinaseNot Annotated
SaruplaseNot Annotated
StreptokinaseA purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DesmoteplaseInvestigated for use/treatment in cerebral ischemia and strokes.
FibrinolysinFibrinolysin assists with the healing of minor burns, superficial wounds, ulcers, surgical wounds, and superficial hematomas.
AstaxanthinInvestigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma.
UrokinaseA low molecular weight form of human urokinase used to treat pulmonary embolism and myocardial infarction as well as to clear IV lines.
DipyridamoleA phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
IloprostA synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH).
EpoprostenolA vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure.
BeraprostFor the treatment of pulmonary hypertension.
PrasugrelA P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI.
CangrelorA P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST).
TriflusalTriflusal is indicated as prophylaxis of thromboembolic disorders. It has been registered in Spain and in other countries of Europe, South America and South Korea for the prevention of Stroke...
TicagrelorA P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death.
DitazoleDitazole is a non-steroidal anti-inflammatory drug (NSAID). Ditazole's analgesic and antipyretic effects are similar to phenylbutazone. Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade...
VorapaxarA platelet aggregation inhibitor used to reduce thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD).
BemiparinBemiparin is indicated in the following cases: To prevent blood clots in the veins after general abdominal surgery in patients with a moderate risk of venous thromboembolism; in the prevention...
ParnaparinUsed in the prevention and treatment of venous thromboembolism (deep vein thrombosis and pulmonary embolism) and in the treatment of myocardial infarction.
ClorindioneClorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans.
DiphenadioneNot Annotated
TioclomarolNot Annotated
LepirudinA protein-based direct thrombin inhibitor used to reverse and prevent thrombus formation in heparin-induced thrombocytopenia.
AlteplaseA recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
ReteplaseA purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
AnistreplaseA form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli.
TocopherylquinoneNot Annotated
AmediplaseInvestigated for use/treatment in myocardial infarction and thrombosis.
4-hydroxycoumarinNot Available
(R)-warfarinWarfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in...
(S)-WarfarinWarfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in...
BetrixabanA Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients.
Edetate calcium disodium anhydrousA chelating agent used to treat lead poisoning.
Zinc citrateAn ingredient found in a variety of supplements and vitamins.
Edetate disodium anhydrousA polyvalent ion chelator indicated for emergency treatment of hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Antithrombin AlfaA recombinant antithrombin used to treat peri-operative and peripartum thromboembolic events in hereditary antithrombin deficiency.
CoumarinNot Available
DabigatranNot Annotated
SemuloparinInvestigated for use/treatment in thrombosis.
MonteplaseMonteplase has been used in trials studying the treatment of Pulmonary Embolism.
Ferric chlorideNot Annotated
GW-813893Not Available
Dermatan sulfateNot Annotated
Drugs & Drug Targets
DrugTargetType
BivalirudinProthrombintarget
BivalirudinMyeloperoxidaseenzyme
AbciximabIntegrin beta-3target
AbciximabLow affinity immunoglobulin gamma Fc region receptor II-atarget
AbciximabLow affinity immunoglobulin gamma Fc region receptor II-btarget
AbciximabIntegrin alpha-IIbtarget
AbciximabVitronectintarget
DicoumarolVitamin K epoxide reductase complex subunit 1target
DicoumarolNAD(P)H dehydrogenase [quinone] 1target
DicoumarolQuinone oxidoreductasetarget
DicoumarolCytochrome P450 2C9enzyme
DicoumarolSerum albumincarrier
DicoumarolCytochrome P450 2C6enzyme
DicoumarolCytochrome P450 2C11enzyme
ArgatrobanProthrombintarget
ArgatrobanCytochrome P450 3A4enzyme
ArgatrobanCytochrome P450 3A5enzyme
ArgatrobanSerum albumincarrier
Argatrobanalpha1-acid glycoproteincarrier
ArdeparinHeparin cofactor 2target
ArdeparinAntithrombin-IIItarget
PhenindioneVitamin K epoxide reductase complex subunit 1target
FondaparinuxAntithrombin-IIItarget
FondaparinuxCoagulation factor Xtarget
WarfarinVitamin K epoxide reductase complex subunit 1target
WarfarinCytochrome P450 2C8enzyme
WarfarinCytochrome P450 1A2enzyme
WarfarinCytochrome P450 2C9enzyme
WarfarinAlpha-1-acid glycoprotein 1carrier
WarfarinSerum albumincarrier
WarfarinCytochrome P450 2C19enzyme
WarfarinCytochrome P450 3A4enzyme
WarfarinCytochrome P450 2C18enzyme
WarfarinNuclear receptor subfamily 1 group I member 2target
Pentosan polysulfateFibroblast growth factor 1target
Pentosan polysulfateFibroblast growth factor 4target
Pentosan polysulfateFibroblast growth factor 2target
PhenprocoumonVitamin K epoxide reductase complex subunit 1target
PhenprocoumonAlpha-1-acid glycoprotein 1carrier
PhenprocoumonSerum albumincarrier
PhenprocoumonCytochrome P450 2C9enzyme
PhenprocoumonCytochrome P450 3A4enzyme
PhenprocoumonCytochrome P450 2C8enzyme
Edetic acidLeadtarget
Edetic acidIrontarget
Edetic acidManganese cationtarget
Edetic acidAdenosine deaminaseenzyme
Edetic acidSerum paraoxonase/lactonase 3enzyme
Edetic acidCytochrome P450 19A1enzyme
HeparinAntithrombin-IIItarget
HeparinCoagulation factor Xtarget
HeparinP-selectintarget
HeparinHeparanaseenzyme
HeparinFibroblast growth factor receptor 4target
HeparinFibroblast growth factor 4target
HeparinFibroblast growth factor 19target
HeparinFibroblast growth factor receptor 1target
HeparinFibroblast growth factor 1target
HeparinFibroblast growth factor receptor 2target
HeparinFibroblast growth factor 2target
HeparinPlatelet factor 4target
HeparinHepatocyte growth factortarget
HeparinThyroxine-binding globulincarrier
EnoxaparinAntithrombin-IIItarget
EnoxaparinCoagulation factor Xtarget
EnoxaparinMyeloperoxidaseenzyme
AcenocoumarolVitamin K epoxide reductase complex subunit 1target
AcenocoumarolCytochrome P450 2C9enzyme
AcenocoumarolCytochrome P450 1A2enzyme
AcenocoumarolSerum albumincarrier
AcenocoumarolAlpha-1-acid glycoprotein 1carrier
AcenocoumarolCytochrome P450 2C19enzyme
AcenocoumarolCytochrome P450 3A4enzyme
AcenocoumarolP-glycoprotein 1transporter
XimelagatranProthrombintarget
XimelagatranCytochrome P450 2C9enzyme
AncrodFibrinogen alpha chaintarget
RivaroxabanCoagulation factor Xtarget
RivaroxabanCytochrome P450 3A4enzyme
RivaroxabanCytochrome P450 2J2enzyme
RivaroxabanP-glycoprotein 1transporter
RivaroxabanCytochrome P450 3A5enzyme
RivaroxabanATP-binding cassette sub-family G member 2transporter
SulodexideHeparin cofactor 2target
SulodexideAntithrombin-IIItarget
IdraparinuxCoagulation factor Xtarget
ApixabanCoagulation factor Xtarget
ApixabanCytochrome P450 3A4enzyme
ApixabanCytochrome P450 1A2enzyme
ApixabanCytochrome P450 2C8enzyme
ApixabanCytochrome P450 2C9enzyme
ApixabanCytochrome P450 2C19enzyme
ApixabanCytochrome P450 2J2enzyme
ApixabanP-glycoprotein 1transporter
ApixabanATP-binding cassette sub-family G member 2transporter
ApixabanCytochrome P450 3A5enzyme
OtamixabanCoagulation factor Xtarget
Dabigatran etexilateProthrombintarget
Dabigatran etexilateP-glycoprotein 1transporter
Dabigatran etexilateLiver carboxylesterase 1enzyme
Dabigatran etexilateCocaine esteraseenzyme
Dabigatran etexilateUDP-glucuronosyltransferase 1-9enzyme
Dabigatran etexilateUDP-glucuronosyltransferase 2B7enzyme
Dabigatran etexilateUDP-glucuronosyltransferase 2B15enzyme
Dabigatran etexilateRibosyldihydronicotinamide dehydrogenase [quinone]enzyme
DanaparoidAntithrombin-IIItarget
DalteparinVascular endothelial growth factor Atarget
DalteparinTissue factor pathway inhibitortarget
DalteparinHeparanaseenzyme
DalteparinAntithrombin-IIItarget
DalteparinP-selectintarget
Ferulic acidEndo-1,4-beta-xylanase Ytarget
Ferulic acidEndo-1,4-beta-xylanase Ztarget
Ferulic acidEst1etarget
Ferulic acidO-methyltransferasetarget
Ethyl biscoumacetateGlutamine synthetaseenzyme
Ethyl biscoumacetateCytochrome P450 3A4enzyme
NadroparinProto-oncogene c-Fostarget
NadroparinMyc proto-oncogene proteintarget
NadroparinP-selectintarget
NadroparinAntithrombin-IIItarget
EdoxabanCoagulation factor Xtarget
EdoxabanP-glycoprotein 1transporter
DesirudinCarboxypeptidase A1enzyme
Protein CCoagulation factor Vtarget
Protein CCoagulation factor VIIItarget
Antithrombin III humanAntithrombin-IIItarget
NafamostatIntercellular adhesion molecule 1target
NafamostatTrypsin-1target
NafamostatKallikrein-1target
NafamostatProthrombintarget
NafamostatCoagulation factor Xtarget
NafamostatCoagulation factor XIItarget
NafamostatSolute carrier family 22 member 1transporter
NafamostatSolute carrier family 22 member 2transporter
GabexateTrypsin-1enzyme
GabexateComplement C1s subcomponentenzyme
GabexateComplement C1r subcomponentenzyme
GabexatePlasma kallikreintarget
GabexateProthrombintarget
GabexatePlasminogentarget
FluindioneCytochrome P450 2C9enzyme
Protein S humanCoagulation factor Vtarget
Protein S humanCoagulation factor Xtarget
Protein S humanVitamin K-dependent protein Ctarget
Sodium citrateMitochondrial 2-oxodicarboxylate carriertransporter
Sodium citrateSolute carrier family 13 member 2transporter
Sodium citrateSolute carrier family 13 member 5transporter
Sodium citrateTricarboxylate transport protein, mitochondrialtransporter
TenecteplaseUrokinase plasminogen activator surface receptortarget
TenecteplasePlasminogen activator inhibitor 1target
TenecteplaseFibrinogen alpha chaintarget
TenecteplasePlasminogen activator inhibitor 2target
TenecteplaseTetranectintarget
TenecteplaseKeratin, type II cytoskeletal 8target
TenecteplaseAnnexin A2target
TenecteplaseCalreticulintarget
TenecteplaseCalnexintarget
TenecteplaseProlow-density lipoprotein receptor-related protein 1target
TenecteplasePlasminogentarget
Drotrecogin alfaCoagulation factor VIIItarget
Drotrecogin alfaCoagulation factor Vtarget
Drotrecogin alfaPlasminogen activator inhibitor 1target
Drotrecogin alfaThrombomodulintarget
Drotrecogin alfaVitamin K-dependent protein Starget
Drotrecogin alfaProthrombintarget
Drotrecogin alfaPlatelet factor 4target
Drotrecogin alfaPlasma serine protease inhibitortarget
Drotrecogin alfaSerpin B6target
Drotrecogin alfaEndothelial protein C receptortarget
DefibrotideAdenosine receptor A1target
DefibrotideAdenosine receptor A2atarget
DefibrotideAdenosine receptor A2btarget
TinzaparinAntithrombin-IIItarget
TinzaparinA disintegrin and metalloproteinase with thrombospondin motifs 4enzyme
TinzaparinIntegrin alpha-4target
TinzaparinStromal cell-derived factor 1target
StreptokinasePlasminogentarget
StreptokinaseProteinase-activated receptor 1target
StreptokinaseCytosolic phospholipase A2enzyme
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
DesmoteplasePlasminogentarget
FibrinolysinPlasminogen activator inhibitor 1target
FibrinolysinUrokinase-type plasminogen activatortarget
AstaxanthinNF-kappa-B inhibitor alphatarget
UrokinaseUrokinase plasminogen activator surface receptortarget
UrokinasePlasminogentarget
UrokinasePlasminogen activator inhibitor 2target
UrokinasePlasminogen activator inhibitor 1target
UrokinasePlasma serine protease inhibitortarget
UrokinaseNidogen-1target
UrokinaseLow-density lipoprotein receptor-related protein 2target
UrokinaseSuppressor of tumorigenicity 14 proteintarget
UrokinaseMacrophage metalloelastaseenzyme
DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DipyridamoleAdenosine deaminasetarget
DipyridamoleMultidrug resistance-associated protein 4transporter
DipyridamoleMultidrug resistance-associated protein 5transporter
DipyridamoleP-glycoprotein 1transporter
DipyridamoleCalcipressin-1target
DipyridamoleAlpha-1-acid glycoprotein 1target
DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DipyridamoleBile salt export pumptransporter
IloprostProstacyclin receptortarget
IloprostTissue-type plasminogen activatortarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IloprostSolute carrier organic anion transporter family member 2B1transporter
IloprostSolute carrier organic anion transporter family member 2A1transporter
IloprostSolute carrier organic anion transporter family member 3A1transporter
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
IloprostProstaglandin E2 receptor EP1 subtypetarget
IloprostProstaglandin D2 receptor 2target
EpoprostenolP2Y purinoceptor 12target
EpoprostenolProstacyclin receptortarget
EpoprostenolProstacyclin synthasetarget
BeraprostProstacyclin receptortarget
BeraprostCytochrome P450 2C8enzyme
PrasugrelP2Y purinoceptor 12target
PrasugrelCocaine esteraseenzyme
PrasugrelCytochrome P450 3A4enzyme
PrasugrelCytochrome P450 2B6enzyme
PrasugrelCytochrome P450 2C9enzyme
PrasugrelCytochrome P450 2C19enzyme
PrasugrelSerum albumincarrier
CangrelorP2Y purinoceptor 12target
TriflusalProstaglandin G/H synthase 1target
TriflusalNuclear factor NF-kappa-B p105 subunittarget
TriflusalNitric oxide synthase, inducibletarget
TriflusalcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
TriflusalSerum albumincarrier
TicagrelorCytochrome P450 3A4enzyme
TicagrelorP2Y purinoceptor 12target
TicagrelorP-glycoprotein 1transporter
TicagrelorCytochrome P450 2C9enzyme
TicagrelorSerum albumincarrier
VorapaxarProteinase-activated receptor 1target
VorapaxarCytochrome P450 3A4enzyme
VorapaxarCytochrome P450 2J2enzyme
VorapaxarP-glycoprotein 1transporter
BemiparinCoagulation factor Xtarget
BemiparinAntithrombin-IIItarget
BemiparinHeparin cofactor 2target
DiphenadioneCytochrome P450 3A4enzyme
LepirudinProthrombintarget
AlteplaseUrokinase plasminogen activator surface receptortarget
AlteplaseFibrinogen alpha chaintarget
AlteplasePlasminogentarget
AlteplasePlasminogen activator inhibitor 1target
ReteplaseFibrinogen alpha chaintarget
ReteplasePlasminogentarget
ReteplasePlasminogen activator inhibitor 1target
AnistreplaseFibrinogen alpha chaintarget
AnistreplasePlasminogentarget
AnistreplasePlasminogen activator inhibitor 1target
4-hydroxycoumarinMajor NAD(P)H-flavin oxidoreductasetarget
(R)-warfarinSerum albumincarrier
(R)-warfarinCytochrome P450 2C8enzyme
(R)-warfarinCytochrome P450 2C9enzyme
(R)-warfarinCytochrome P450 2C18enzyme
(R)-warfarinCytochrome P450 2C19enzyme
(R)-warfarinCytochrome P450 1A2enzyme
(R)-warfarinCytochrome P450 1A1enzyme
(R)-warfarinCytochrome P450 3A4enzyme
(S)-WarfarinCytochrome P450 3A4enzyme
(S)-WarfarinCytochrome P450 2C8enzyme
(S)-WarfarinCytochrome P450 2C9enzyme
(S)-WarfarinCytochrome P450 2C18enzyme
(S)-WarfarinCytochrome P450 2C19enzyme
BetrixabanP-glycoprotein 1transporter
BetrixabanCoagulation factor Xtarget
BetrixabanPotassium voltage-gated channel subfamily H member 2transporter
BetrixabanProthrombinenzyme
Edetate calcium disodium anhydrousManganese cationtarget
Edetate calcium disodium anhydrousIrontarget
Edetate calcium disodium anhydrousLeadtarget
Edetate calcium disodium anhydrousAdenosine deaminaseenzyme
Edetate calcium disodium anhydrousSerum paraoxonase/lactonase 3enzyme
Edetate calcium disodium anhydrousCytochrome P450 19A1enzyme
Edetate calcium disodium anhydrousCytochrome P450 3A4enzyme
Edetate calcium disodium anhydrousSerum paraoxonase/arylesterase 1enzyme
Edetate disodium anhydrousLeadtarget
Edetate disodium anhydrousIrontarget
Edetate disodium anhydrousManganese cationtarget
Edetate disodium anhydrousAdenosine deaminaseenzyme
Edetate disodium anhydrousSerum paraoxonase/lactonase 3enzyme
Edetate disodium anhydrousCytochrome P450 19A1enzyme
Edetate disodium anhydrousCytochrome P450 3A4enzyme
Edetate disodium anhydrousSerum paraoxonase/arylesterase 1enzyme
Antithrombin AlfaProthrombintarget
Antithrombin AlfaCoagulation factor Xtarget
CoumarinCytochrome P450 2A6target
CoumarinCytochrome P450 2C9enzyme
GW-813893Prothrombintarget
GW-813893Coagulation factor Xtarget