Peptide Hormones
- Name
- Peptide Hormones
- Accession Number
- DBCAT000055
- Description
Hormones synthesized from amino acids. They are distinguished from INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS in that their actions are systemic.
- Drugs
Drug Drug Description .gamma.-brain natriuretic peptide Not Annotated Abaloparatide A parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in patients with a high risk of fracture. Aclerastide Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic. Adrenomedullin Adrenomedullin is under investigation in clinical trial NCT06072118 (Adrenomedullin for CADASIL). Albusomatropin Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency. Alsactide Not Annotated Amlintide A medication used in combination with corticosteroids for the treatment of hemorrhoids. Anamorelin Investigated for use/treatment in cachexia and anorexia. Anaritide Not Annotated Angiotensin 1-7 TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities. Angiotensin II A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. AOD9604 Investigated for use/treatment in obesity and osteoporosis. AP-102 Not Annotated Atilmotin Atilmotin is a small molecule drug. Atilmotin has a monoisotopic molecular weight of 1751.01 Da. Atosiban An inhibitor of oxytocin and vasopressin used to delay imminent preterm birth in pregnant adult women displaying specific clinical observations. Atrial natriuretic peptide Not Annotated Aviptadil Not Annotated Bombesin Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and... Bremelanotide Bremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of... Buserelin A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females. C-peptide C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy). Cagrilintide Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2... Carbetocin An oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth. Cargutocin Cargutocin is a small molecule drug. Cargutocin has a monoisotopic molecular weight of 915.48 Da. Cenderitide Cenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall. Cetrorelix A synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy. Chorionic Gonadotropin (Human) A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women. Corifollitropin alfa A FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program. Corticorelin A synthetic corticotropin-releasing factor analog used to diagnose causes of excessive adrenocorticotropic hormone (ACTH) production. Corticorelin ovine triflutate A synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome. Corticotropin A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Dasiglucagon A glucagon analog used to treat severe hypoglycemia in pediatric and adult patients with diabetes. Demoxytocin Not Annotated Deslorelin Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones. Desmopressin A synthetic vasopressin (antidiuretic hormone) analog and $V_2$ receptor agonist used as replacement therapy for central diabetes insipidus, and as a prohemostatic agent to increase Factor VIII and von Willebrand factor levels in patients with Hemophilia A or Type 1 von Willebrand disease. Detirelix Detirelix is a small molecule drug. The usage of the INN stem '-relix' in the name indicates that Detirelix is a gonadotropin-releasing-hormone (GnRH) inhibitor. Detirelix has a monoisotopic molecular weight... Dopastatin Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas). Dulaglutide A GLP-1 agonist used to manage type 2 diabetes mellitus. Ebiratide Ebiratide is a small molecule drug. Ebiratide has a monoisotopic molecular weight of 995.53 Da. Eftansomatropin alfa Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency. Elcatonin Not Annotated Felypressin For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. Follitropin A form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism. G17DT Immunogen Intended for the treatment of various forms of cancer. Ganirelix A GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges. Gastric inhibitory polypeptide Gastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea). Glucagon A form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures. Gonadorelin A synthetic GnRH used to test the function of gonadotropes and the pituitary. Goserelin A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary. Histrelin A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer. Indium In-111 pentetreotide Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome. Insulin aspart A rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin degludec A long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus. Insulin detemir A long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Insulin glulisine A short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin human A recombinant form of human insulin used to control hyperglycemia in diabetes mellitus. Insulin icodec An ultra long-acting basal insulin analogue for once-weekly injection in patients with diabetes mellitus. Insulin lispro A modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus. Insulin peglispro Not Annotated Insulin pork A purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. Intermedine Not Annotated Lanreotide A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. Lenomorelin Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others. Leptin Investigated for use/treatment in lipodystrophy and obesity. Liraglutide A GLP-1 analog used in the management of type 2 diabetes mellitus, prevention of cardiovascular complications associated with diabetes, and obesity. Livoletide Livoletide is under investigation in clinical trial NCT03790865 (Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome). Lonapegsomatropin A human growth hormone indicated in the treatment of growth failure due to inadequate endogenous growth hormone secretion. Luteinizing hormone Not Annotated Lypressin Not Annotated Menotropins A purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility. Metreleptin A leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients various forms of lipodystrophy. Minigastrin Minigastrin is under investigation in clinical trial NCT06155994 (68ga-dota-mgs5 PET/CT in Patients With Advanced Neuroendocrine Tumours). Montirelin Montirelin is a small molecule drug. The usage of the INN stem '-tirelin' in the name indicates that Montirelin is a thyrotropin releasing hormone analogue. Montirelin has a monoisotopic molecular... Nacartocin Nacartocin is a small molecule drug. Nacartocin has a monoisotopic molecular weight of 985.51 Da. Nafarelin A gonadotropin releasing hormone agonist used to treat central precocious puberty. NBI-6024 Investigated for use/treatment in diabetes mellitus type 1 and pediatric indications. Nesiritide A recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. NN344 Investigated for use/treatment in diabetes mellitus type 1 and 2. Ornipressin Not Annotated Orotirelin Orotirelin is a small molecule drug. The usage of the INN stem '-tirelin' in the name indicates that Orotirelin is a thyrotropin releasing hormone analogue. Orotirelin has a monoisotopic molecular... Ostabolin-C Investigated for use/treatment in menopause and osteoporosis. Oxytocin A recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding. Palopegteriparatide A parathyroid hormone analog used to treat hyperparathyroidism in adults. Pancreatic Polypeptide Pancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1. Parathyroid hormone An analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism. Parathyroid Hormone-Related Protein 1-36 Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and PTH to Treat Osteoporosis). Pareptide Pareptide is a small molecule drug. Pareptide has a monoisotopic molecular weight of 298.2 Da. Pasireotide A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. Pegvisomant A growth hormone receptor antagonist used to treat acromegaly. Pegylated synthetic human c-peptide Not Annotated Pentetreotide A somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours. Peptide YY (1-36) Not Available Peptide YY (3-36) Investigated for use/treatment in metabolic disease and obesity. Pirnabine Pirnabine has been used in trials studying the treatment of Chronic Idiopathic Constipation. Plecanatide A laxative used to treat chronic idiopathic constipation and IBS with constipation. Posatirelin Posatirelin is a small molecule drug. The usage of the INN stem '-tirelin' in the name indicates that Posatirelin is a thyrotropin releasing hormone analogue. Posatirelin has a monoisotopic molecular... Pramlintide An amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy. Procalcitonin Procalcitonin is under investigation in clinical trial NCT03440060 (Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD). Progranulin Not Available Proinsulin human Not Annotated Protirelin A synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland. Salmon calcitonin A synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease. Secretin human A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. Selepressin Selepressin has been used in trials studying the treatment of Septic Shock. Semaglutide A glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus, treat obesity, and reduce the risk of major adverse cardiovascular events in selected adults. Semparatide Semparatide is a small molecule drug. The usage of the INN stem '-paratide' in the name indicates that Semparatide is a parathyroid hormone analogue. Semparatide has a monoisotopic molecular weight... Sermorelin For the treatment of dwarfism, prevention of HIV-induced weight loss Setmelanotide A drug indicated to treat obesity caused by genetic POMC, PCSK1, or LEPR deficiencies or Bardet-Biedl syndrome. Somapacitan A human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency. Somatorelin A synthetic version of growth hormone-releasing hormone used in the diagnosis of growth hormone deficiency. Somatostatin A natural peptide hormone used to treat acute bleeding from esophageal varices, gastrointestinal ulcers, and gastritis; prevent pancreatic complications after surgery; and restrict secretions of the upper intestine, pancreas, and biliary tract. Somatotropin A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults. Somatrem A recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age. Somatrogon A long-acting recombinant human growth hormone used as the long-term treatment of pediatric patients who have growth failure due to growth hormone deficiency. Somatropin pegol Somatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083). Taltirelin Taltirelin is a small molecule drug. The usage of the INN stem '-tirelin' in the name indicates that Taltirelin is a thyrotropin releasing hormone analogue. Taltirelin has a monoisotopic molecular... Teriparatide A recombinant parathyroid hormone used for the treatment of osteoporosis. Terlipressin A drug used to treat bleeding caused by esophageal varices. Tesamorelin A growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy. Tetracosactide A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Thymalfasin Indicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate... Thyrotropin A medication indicated in thyroid stimulation before radioactive iodine ablation or for thyroid imaging. Thyrotropin alfa A recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue. Timbetasin Timbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2). Tirzepatide A dual GIP and GLP-1 receptor agonist used for the treatment of type II diabetes in adults as an adjunct to diet and exercise. TP-3654 Not Annotated Triptorelin A GnRH agonist indicated for the palliative treatment of advanced prostate cancer. TT-232 Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma). Ularitide Investigated for use/treatment in congestive heart failure. Urocortin-2 Urocortin 2 has been investigated for the basic science of Heart Failure and Cardiovascular Disease. Urofollitropin A form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure. Vapreotide For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea. Vasoactive intestinal peptide Not Annotated Vasomera Not Available Vasopressin A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. Veldoreotide Somatoprim is under investigation for the treatment of Acromegaly. Vosoritide An analogue of C-type naturietic peptide used to promote bone growth in pediatric patients with achondroplasia. Zoptarelin doxorubicin Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. - Drugs & Drug Targets