- Peptide Hormones
- Accession Number
Hormones synthesized from amino acids. They are distinguished from INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS in that their actions are systemic.
Drug Drug Description Sermorelin For the treatment of dwarfism, prevention of HIV-induced weight loss Goserelin A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary. Insulin human A recombinant form of human insulin used to control hyperglycemia in diabetes mellitus. Desmopressin A synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia. Glucagon A form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures. Insulin lispro A modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus. Somatotropin A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults. Vasopressin A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. Oxytocin A recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding. Insulin detemir A long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin glulisine A short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Parathyroid hormone An analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism. Liraglutide A GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes. Lanreotide A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. Dulaglutide A GLP-1 agonist used to manage type 2 diabetes mellitus. Metreleptin A leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy. Somatrem A recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age. Insulin degludec A long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus. Deslorelin Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones. Bremelanotide Bremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of... Setmelanotide Setmelanotide is indicated to treat obesity caused by genetic POMC, PCSK1, or LEPR deficiencies or Bardet-Biedl syndrome. Lenomorelin Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others. Vosoritide An analogue of C-type naturietic peptide used to promote bone growth in pediatric patients with achondroplasia. Urocortin-2 Urocortin 2 has been investigated for the basic science of Heart Failure and Cardiovascular Disease. Semaglutide A glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus. Secretin human A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. Luteinizing hormone Not Annotated Somapacitan A human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency. Dasiglucagon A glucagon analog used to treat severe hypoglycemia in pediatric and adult patients with diabetes. Somatrogon A long-acting recombinant human growth hormone used as the long-term treatment of pediatric patients who have growth failure due to growth hormone deficiency. Salmon calcitonin A synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease. Angiotensin 1-7 TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities. Bombesin Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and... Angiotensin II A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. Aclerastide Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic. Procalcitonin Procalcitonin is under investigation in clinical trial NCT03440060 (Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD). Gastric inhibitory polypeptide Gastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea). Thyrotropin alfa A recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue. Menotropins A purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility. Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Cetrorelix A synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy. Follitropin A form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism. Insulin pork A purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. Pegvisomant A growth hormone receptor antagonist used to treat acromegaly. Felypressin For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. Urofollitropin A form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure. Gonadorelin A synthetic GnRH used to test the function of gonadotropes and the pituitary. Nafarelin A gonadotropin releasing hormone agonist used to treat central precocious puberty. Pramlintide An amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy. Carbetocin An oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth. Tetracosactide A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Corticotropin A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Insulin aspart A rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Terlipressin A drug used to treat bleeding caused by esophageal varices. Vapreotide For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea. Nesiritide A recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. Thymalfasin Indicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate... G17DT Immunogen Intended for the treatment of various forms of cancer. Peptide YY (3-36) Investigated for use/treatment in metabolic disease and obesity. Ularitide Investigated for use/treatment in congestive heart failure. Abaloparatide A parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in patients with a high risk of fracture. Leptin Investigated for use/treatment in lipodystrophy and obesity. NN344 Investigated for use/treatment in diabetes mellitus type 1 and 2. Corticorelin A synthetic corticotropin-releasing factor analog used to diagnose causes of excessive adrenocorticotropic hormone (ACTH) production. NBI-6024 Investigated for use/treatment in diabetes mellitus type 1 and pediatric indications. Aviptadil Not Annotated Teriparatide A recombinant parathyroid hormone used for the treatment of osteoporosis. Anamorelin Investigated for use/treatment in cachexia and anorexia. Pasireotide A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. Buserelin A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females. Ganirelix A GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges. Histrelin A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer. Triptorelin A GnRH agonist indicated for the palliative treatment of advanced prostate cancer. Tesamorelin A growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy. Atosiban An inhibitor of oxytocin and vasopressin used to delay imminent preterm birth in pregnant adult women displaying specific clinical observations. Corifollitropin alfa A FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program. Corticorelin ovine triflutate A synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome. Somatostatin A natural peptide hormone used to treat acute bleeding from esophageal varices, gastrointestinal ulcers, and gastritis; prevent pancreatic complications after surgery; and restrict secretions of the upper intestine, pancreas, and biliary tract. Chorionic Gonadotropin (Human) A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women. Protirelin A synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland. Insulin peglispro Not Annotated Cenderitide Cenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall. Indium In-111 pentetreotide Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome. Thymosin beta-4 Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, and Dry Eye Syndrome, among others. TT-232 Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma). Selepressin Selepressin has been used in trials studying the treatment of Septic Shock. Pentetreotide A somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours. Zoptarelin doxorubicin Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. Veldoreotide Somatoprim is under investigation for the treatment of Acromegaly. Pancreatic Polypeptide Pancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1. Pirnabine Pirnabine has been used in trials studying the treatment of Chronic Idiopathic Constipation. Albusomatropin Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency. Plecanatide A laxative used to treat chronic idiopathic constipation and IBS with constipation. Alsactide Not Annotated Ornipressin Not Annotated Elcatonin Not Annotated Demoxytocin Not Annotated Lypressin Not Annotated Somatropin pegol Somatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083). Tirzepatide A dual GIP and GLP-1 receptor agonist used for the treatment of type II diabetes in adults as an adjunct to diet and exercise. Thyrotropin A medication indicated in thyroid stimulation before radioactive iodine ablation or for thyroid imaging. Atrial natriuretic peptide Not Annotated Dopastatin Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas). C-peptide C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy). Parathyroid Hormone-Related Protein 1-36 Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and PTH to Treat Osteoporosis). Pegylated synthetic human c-peptide Not Annotated Vasomera Not Available Amlintide A medication used in combination with corticosteroids for the treatment of hemorrhoids. Insulin icodec Not Annotated Lonapegsomatropin A human growth hormone indicated in the treatment of growth failure due to inadequate endogenous growth hormone secretion. Intermedine Not Annotated Anaritide Not Annotated Proinsulin human Not Annotated Livoletide Livoletide is under investigation in clinical trial NCT03790865 (Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome). Somatorelin A synthetic version of growth hormone-releasing hormone used in the diagnosis of growth hormone deficiency. TP-3654 Not Annotated AP-102 Not Annotated Peptide YY (1-36) Not Available Progranulin Not Available Eftansomatropin alfa Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency. Vasoactive intestinal peptide Not Annotated
- Drugs & Drug Targets