Hematinics

Name
Hematinics
Accession Number
DBCAT000087
Description

Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.

Drugs
DrugDrug Description
Darbepoetin alfaA recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
EltrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
ErythropoietinA recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
Ferric derisomaltoseAn iron injection used in the treatment of iron deficiency anemia.
Ferric maltolA complexed iron supplement used to treat iron deficiency in adults and pediatrics.
Ferric sulfateA medication used as a coagulant and hemostatic agent.
Ferrous gluconateA medication used to treat iron-deficiency anemia.
Ferrous succinateAn iron supplement indicated in the treatment of iron deficiency anemia.
Ferrous sulfate anhydrousAn iron supplement used to prevent or treat iron deficiency anemia.
FerumoxytolAn intravenous iron replacement product used to treat iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD), or in patients who are unable to tolerate or who have not responded adequately to oral iron supplementation.
Folic acidA nutrient used to treat megaloblastic anemia and is found in many supplements.
HydroxocobalaminA synthetic form of vitamin B12 used to treat vitamin B12 associated disorders and cyanide poisoning.
Iron DextranAn iron supplement used to treat iron deficiency in patients who cannot take oral iron.
Iron isomaltoside 1000Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney...
Iron polymaltoseNot Annotated
Iron protein succinylateNot Annotated
LuspaterceptAn erythroid maturation agent used to treat anemia secondary to beta thalassemia, myelodysplastic syndromes, and neoplasms.
Methoxy polyethylene glycol-epoetin betaA synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease.
PegfilgrastimA recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.
PlerixaforA CXCR4 antagonist used in combination with granulocyte-colony stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and autologous transplantation in patients with non-Hodgkin’s lymphoma and multiple myeloma.
Drugs & Drug Targets
DrugTargetType
Darbepoetin alfaErythropoietin receptortarget
EltrombopagCytochrome P450 1A2enzyme
EltrombopagUDP-glucuronosyltransferase 1A1enzyme
EltrombopagUDP-glucuronosyltransferase 1A9enzyme
EltrombopagBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
EltrombopagSolute carrier organic anion transporter family member 1B1transporter
EltrombopagUDP-glucuronosyltransferase 1A3enzyme
EltrombopagCytochrome P450 2C8enzyme
EltrombopagThrombopoietin receptortarget
ErythropoietinErythropoietin receptortarget
Ferric derisomaltoseTransferrin receptortarget
Ferric derisomaltoseHemoglobin subunit alphatarget
Ferric derisomaltoseTransferrin receptortransporter
Ferric maltolIntegrin beta-3transporter
Ferric maltolNatural resistance-associated macrophage protein 2transporter
Ferric maltolNatural resistance-associated macrophage protein 2target
Ferric maltolIntegrin beta-3target
Ferric maltolUDP-glucuronosyltransferase 1A6enzyme
Ferrous gluconateSerotransferrintarget
Ferrous gluconateTransferrin receptor protein 1target
Ferrous gluconateEgl nine homolog 1target
Ferrous gluconateHistone deacetylase 8target
Ferrous gluconateAlpha-hemoglobin-stabilizing proteintarget
Ferrous gluconateHemoglobin subunit alphatarget
Ferrous gluconateFrataxin, mitochondrialtarget
Ferrous gluconateFerritin heavy chaintarget
Ferrous gluconateFlap endonuclease 1target
Ferrous gluconateEndonuclease 8-like 1target
Ferrous gluconateEndonuclease 8-like 2target
Ferrous gluconateDNA polymerase betatarget
Ferrous gluconateCeruloplasmintarget
Ferrous succinateCeruloplasmintarget
Ferrous succinateTransferrin receptor protein 1target
Ferrous succinateSerotransferrintarget
Ferrous succinateEgl nine homolog 1target
Ferrous succinateHistone deacetylase 8target
Ferrous succinateAlpha-hemoglobin-stabilizing proteintarget
Ferrous succinateHemoglobin subunit alphatarget
Ferrous succinateFrataxin, mitochondrialtarget
Ferrous succinateFerritin heavy chaintarget
Ferrous succinateFlap endonuclease 1target
Ferrous succinateEndonuclease 8-like 1target
Ferrous succinateEndonuclease 8-like 2target
Ferrous succinateDNA polymerase betatarget
Ferrous sulfate anhydrousNatural resistance-associated macrophage protein 2transporter
Ferrous sulfate anhydrousCeruloplasminenzyme
Ferrous sulfate anhydrousHemoglobin subunit alphatarget
Ferrous sulfate anhydrousFerroportintransporter
Ferrous sulfate anhydrousHepcidinenzyme
Ferrous sulfate anhydrousSerotransferrinenzyme
Ferrous sulfate anhydrousHephaestinenzyme
Ferrous sulfate anhydrousPlasma membrane ascorbate-dependent reductase CYBRD1enzyme
Ferrous sulfate anhydrousTransferrin receptortarget
FerumoxytolMacrophage scavenger receptor types I and IItarget
FerumoxytolSerotransferrincarrier
Folic acidFolate receptor betatarget
Folic acidFolate receptor gammatarget
Folic acidSolute carrier family 25 member 32transporter
Folic acidMethylenetetrahydrofolate reductase (NADPH)enzyme
Folic acidATP-binding cassette sub-family C member 4transporter
Folic acidSolute carrier family 22 member 6transporter
Folic acidProton-coupled folate transportertransporter
Folic acidATP-binding cassette sub-family C member 3transporter
Folic acidATP-binding cassette sub-family C member 11transporter
Folic acidBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
Folic acidGamma-glutamyl hydrolaseenzyme
Folic acidFolate receptor alphatarget
Folic acidDihydrofolate reductaseenzyme
Folic acidProton-coupled folate transportertarget
Folic acidReduced folate transportertarget
HydroxocobalaminMethylmalonic aciduria type A protein, mitochondrialtarget
HydroxocobalaminProtein amnionlesstarget
HydroxocobalaminTranscobalamin-1target
HydroxocobalaminMethylmalonyl-CoA mutase, mitochondrialtarget
HydroxocobalaminMethionine synthasetarget
HydroxocobalaminCubilintarget
HydroxocobalaminTranscobalamin-2carrier
HydroxocobalaminCyanocobalamin reductase / alkylcobalamin dealkylasetarget
Iron DextranHemoglobin subunit betatarget
Iron DextranHemoglobin subunit alphatarget
Iron DextranFerritin heavy chaintarget
Iron DextranFerritin light chaintarget
Iron DextranSerotransferrincarrier
Iron isomaltoside 1000Serotransferrincarrier
Iron isomaltoside 1000Ferritincarrier
Iron polymaltoseFerritincarrier
Iron protein succinylateCaseincarrier
Iron protein succinylateCaseintarget
LuspaterceptGrowth/differentiation factor 11target
LuspaterceptInhibin beta B chaintarget
Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
PegfilgrastimGranulocyte colony-stimulating factor receptortarget
PegfilgrastimNeutrophil elastaseenzyme
PlerixaforC-X-C chemokine receptor type 4target