Gonadotropins, Pituitary

Name
Gonadotropins, Pituitary
Accession Number
DBCAT000106
Description

Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR) that stimulate gonadal functions in both males and females. They include FOLLICLE STIMULATING HORMONE that stimulates germ cell maturation (OOGENESIS; SPERMATOGENESIS), and LUTEINIZING HORMONE that stimulates the production of sex steroids (ESTROGENS; PROGESTERONE; ANDROGENS).

Drugs
DrugDrug Description
MenotropinsA purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility.
FollitropinA form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism.
UrofollitropinA form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure.
Luteinizing hormoneNot Annotated
Chorionic Gonadotropin (Human)A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women.
Corifollitropin alfaA FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program.
Drugs & Drug Targets
DrugTargetType
MenotropinsFollicle-stimulating hormone receptortarget
MenotropinsLutropin-choriogonadotropic hormone receptortarget
FollitropinFollicle-stimulating hormone receptortarget
UrofollitropinFollicle-stimulating hormone receptortarget
Chorionic Gonadotropin (Human)Lutropin-choriogonadotropic hormone receptortarget
Corifollitropin alfaFollicle-stimulating hormone receptortarget