Complex Mixtures
- Name
- Complex Mixtures
- Accession Number
- DBCAT000109
- Description
Mixtures of many components in inexact proportions, usually natural, such as PLANT EXTRACTS; VENOMS; and MANURE. These are distinguished from DRUG COMBINATIONS which have only a few components in definite proportions.
- Drugs
Drug Drug Description Menotropins A purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility. Botulinum Toxin Type B A purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea. Pancrelipase A purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis. Urofollitropin A form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure. Antithymocyte immunoglobulin (rabbit) A purified form of rabbit anti-thymocyte antibodies used for immunosuppression in patients receiving kidney transplants. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Ethiodized oil A contrast agent used in imaging procedures. Bufotenine A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a... Camphor A compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed. Ricinoleic Acid Not Available Choline alfoscerate A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes... G17DT Intended for the treatment of various forms of cancer. BZL101 Investigated for use/treatment in breast cancer. Ancrod An anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country. INGN 201 Investigated for use/treatment in bladder cancer, brain cancer, breast cancer, esophageal cancer, head and neck cancer, lung cancer, oral cavity cancer, ovarian cancer, and prostate cancer. INGN 225 Investigated for use/treatment in breast cancer, head and neck cancer, and lung cancer. Rindopepimut Investigated for use/treatment in brain cancer. AE-941 Investigated for use/treatment in kidney cancer, lung cancer, macular degeneration, multiple myeloma, prostate cancer, and psoriasis and psoriatic disorders. SRP 299 Investigated for use/treatment in asthma, atopic dermatitis, and pediatric atopic dermatitis indications. TA-NIC Investigated for use/treatment in tobacco dependence. Andrographolide Investigated for use/treatment in ulcerative colitis. LLL-3348 Investigated for use/treatment in psoriasis and psoriatic disorders. GI-5005 Investigated for use/treatment in hepatitis (viral, C). Ziconotide An N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics. Calfactant A lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants. TG4010 Investigated for use/treatment in breast cancer, renal cell carcinoma, prostate cancer, and lung cancer. Sipuleucel-T An autologous cellular immunotherapy indicated for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer. Beractant A pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants. Serotonin For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product. Batroxobin No approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously. Podophyllin A cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata). Poractant alfa A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Soybean oil An oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency. Safflower oil No approved therapeutic indications. Ferumoxsil Not Annotated Methyl salicylate A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons. Olive oil For use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products. Varicella Zoster Vaccine (Live/attenuated) Zostavax vaccine is indicated for the prevention of herpes zoster (shingles) in immunocompetent adults aged 50 years and older. Varivax vaccine is indicated for active immunization for the prevention of... Karaya gum An extract from Karaya gum used in allergy testing. Clostridium tetani toxoid antigen (formaldehyde inactivated) Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention... Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) Not Annotated Tragacanth An extract from Tragacanth used in allergy testing. Carob An extract from Carob used in allergy testing. Coal tar Relieving itching, irritation, redness, dryness, scaling, and flaking of the skin caused by psoriasis, seborrhea, or eczema. Plantago seed An ingredient used in a variety of natural health products. Castor oil An ingredient used in a variety of natural health products. Turpentine A medication used to treat minor aches and pains of muscles and joints. Opium A medication used to treat moderate to severe pain. Capsicum oleoresin A medication used to treat minor aches and pains of muscles and joints. Silicon dioxide An ingredient found in a variety of supplements and vitamins. Pectin Pectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary... Rosin An extract from Rosin used in allergy testing. Sesame oil Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic... Peppermint oil An ingredient used in a variety of natural health products and is not an approved medication. Tea tree oil Indicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications. Benzoin resin A compound used to protect small wounds or canker sores. Tolu balsam Not Annotated Borage oil Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as... Rice bran oil Rice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It... Clove oil Clove oil is primarily indicated in conditions like colic, flatulence, and toothache . Linseed oil Linseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic... Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Sennosides A laxative used to treat constipation. Balsam of Peru Balsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of... Human Varicella-Zoster Immune Globulin A solution of antibodies used for post exposure prophylaxis of varicella infections in high risk populations, as well as to reduce the severity of infections. Bombesin Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and... Cenderitide Cenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall. Cilengitide Cilengitide has been used in trials studying the treatment of Sarcoma, Gliomas, Lymphoma, Leukemia, and Lung Cancer, among others. Tecemotide Tecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung. Aviscumine Cy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy). BCG vaccine BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others. Norflurane Norflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage). Levomenol Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain... Ipecac An emetic agent used to induce vomiting in poisoning. Guar gum Not Annotated Peanut oil A compound used to lubricate ear wax, as an emollient, and used in laxatives. Bos taurus gallstone Bos taurus gallstone is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug. Turmeric Turmeric is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Panax notoginseng root Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Meadowfoam seed oil Meadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Argan oil Argan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Tangerine peel Tangerine peel is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Coconut oil Coconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Amber Amber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Sunflower oil Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Nelumbo nucifera flower Nelumbo nucifera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Bergamot oil Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Angelica sinensis root Angelica sinensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Forsythia suspensa fruit Forsythia suspensa fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Saw palmetto Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Scutellaria baicalensis root Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Palm oil Palm oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Sophora flavescens root Not Annotated Lavender oil Not Annotated Plantago ovata seed Not Annotated alpha-Conotoxin VC 1.1 Investigated for use/treatment in pain (acute or chronic). Emodin Emodin has been investigated for the treatment of Polycystic Kidney. Phleum pratense pollen An extract from Phleum pratense pollen used in allergy testing. Yellow Fever Vaccine Yellow Fever Vaccine is indicated for active immunization for the prevention of yellow fever in persons 9 months of age and older in the following categories: Persons Living in or... Ginkgo biloba Appears to be effective in: alleviating age-related memory impairment in some elderly people with mild to moderate age-related memory or cognitive impairment; improving cognitive function in healthy young to middle-aged... Vitespen Investigated for use/treatment in kidney cancer, melanoma, renal cell carcinoma, lymphoma (unspecified), colorectal cancer, and brain cancer. Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females). Anfibatide Anfibatide is under investigation in clinical trial NCT01585259 (Anfibatide Phase Ib-IIa Clinical Trial). Chlorotoxin Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma). VB-201 VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis). Pertussis vaccine Pertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy). Tozuleristide Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery). Yersinia pestis 195/p antigen (formaldehyde inactivated) Yersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine). Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Adalimumab A monoclonal anti-tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. Infliximab A monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. Obiltoxaximab A monoclonal antibody used for prophylaxis or treatment of inhalational anthrax. Chlorotoxin I-131 Investigated for use/treatment in various forms of brain cancer; Malignant Glioma, Glioblastoma Multiforme, GBM, Anaplastic Astrocytoma, Oligo-Astrocytoma, Gliosarcoma Eucalyptus oil An ingredient used in a variety of natural health products. Talimogene laherparepvec A genetically modified virus used to treat recurrent melanoma, or metastatic melanoma. Alloin Not Annotated Frangula purshiana bark Not Annotated beta-Apopicropodophyllin beta-Apopicropodophyllin is a component of the freshwater plant Micranthemum umbrosum. Acacia An extract from Acacia used in allergy testing. Maritime pine extract Not Annotated Solcoseryl Not Annotated Lecithin A complex mixture of phospholipids, glycolipids, triglycerides, phosphatidylcholines, phosphatidylethanolamines, and phosphatidylinositols. Hawthorn leaf with flower Not Annotated IMM-101 IMM-101 is a heat-inactivated immune-activating mycobacterial product. It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma[A220013,A220018,A220023]. Studies... - Drugs & Drug Targets