Complex Mixtures

Name
Complex Mixtures
Accession Number
DBCAT000109
Description

Mixtures of many components in inexact proportions, usually natural, such as PLANT EXTRACTS; VENOMS; and MANURE. These are distinguished from DRUG COMBINATIONS which have only a few components in definite proportions.

Drugs
DrugDrug Description
MenotropinsA purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility.
Botulinum Toxin Type BA purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea.
PancrelipaseA purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.
UrofollitropinA form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure.
Antithymocyte immunoglobulin (rabbit)A purified form of rabbit anti-thymocyte antibodies used for immunosuppression in patients receiving kidney transplants.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Ethiodized oilA contrast agent used in imaging procedures.
BufotenineA hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a...
CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
Ricinoleic AcidNot Available
Choline alfoscerateA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes...
G17DTIntended for the treatment of various forms of cancer.
BZL101Investigated for use/treatment in breast cancer.
AncrodAn anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country.
INGN 201Investigated for use/treatment in bladder cancer, brain cancer, breast cancer, esophageal cancer, head and neck cancer, lung cancer, oral cavity cancer, ovarian cancer, and prostate cancer.
INGN 225Investigated for use/treatment in breast cancer, head and neck cancer, and lung cancer.
RindopepimutInvestigated for use/treatment in brain cancer.
AE-941Investigated for use/treatment in kidney cancer, lung cancer, macular degeneration, multiple myeloma, prostate cancer, and psoriasis and psoriatic disorders.
SRP 299Investigated for use/treatment in asthma, atopic dermatitis, and pediatric atopic dermatitis indications.
TA-NICInvestigated for use/treatment in tobacco dependence.
AndrographolideInvestigated for use/treatment in ulcerative colitis.
LLL-3348Investigated for use/treatment in psoriasis and psoriatic disorders.
GI-5005Investigated for use/treatment in hepatitis (viral, C).
ZiconotideAn N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics.
CalfactantA lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants.
TG4010Investigated for use/treatment in breast cancer, renal cell carcinoma, prostate cancer, and lung cancer.
Sipuleucel-TAn autologous cellular immunotherapy indicated for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.
BeractantA pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants.
SerotoninFor temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
BatroxobinNo approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously.
PodophyllinA cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata).
Poractant alfaA pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants.
Soybean oilAn oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency.
Safflower oilNo approved therapeutic indications.
FerumoxsilNot Annotated
Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
Olive oilFor use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products.
Varicella Zoster Vaccine (Live/attenuated)Zostavax vaccine is indicated for the prevention of herpes zoster (shingles) in immunocompetent adults aged 50 years and older. Varivax vaccine is indicated for active immunization for the prevention of...
Karaya gumAn extract from Karaya gum used in allergy testing.
Clostridium tetani toxoid antigen (formaldehyde inactivated)Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention...
Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)Not Annotated
TragacanthAn extract from Tragacanth used in allergy testing.
CarobAn extract from Carob used in allergy testing.
Coal tarRelieving itching, irritation, redness, dryness, scaling, and flaking of the skin caused by psoriasis, seborrhea, or eczema.
Plantago seedAn ingredient used in a variety of natural health products.
Castor oilAn ingredient used in a variety of natural health products.
TurpentineA medication used to treat minor aches and pains of muscles and joints.
OpiumA medication used to treat moderate to severe pain.
Capsicum oleoresinA medication used to treat minor aches and pains of muscles and joints.
Silicon dioxideAn ingredient found in a variety of supplements and vitamins.
PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
RosinAn extract from Rosin used in allergy testing.
Sesame oilSesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic...
Peppermint oilAn ingredient used in a variety of natural health products and is not an approved medication.
Tea tree oilIndicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications.
Benzoin resinA compound used to protect small wounds or canker sores.
Tolu balsamNot Annotated
Borage oilBorage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as...
Rice bran oilRice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It...
Clove oilClove oil is primarily indicated in conditions like colic, flatulence, and toothache .
Linseed oilLinseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic...
Evening primrose oilEvening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical...
SennosidesA laxative used to treat constipation.
Balsam of PeruBalsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of...
Human Varicella-Zoster Immune GlobulinA solution of antibodies used for post exposure prophylaxis of varicella infections in high risk populations, as well as to reduce the severity of infections.
BombesinBombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and...
CenderitideCenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall.
CilengitideCilengitide has been used in trials studying the treatment of Sarcoma, Gliomas, Lymphoma, Leukemia, and Lung Cancer, among others.
TecemotideTecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung.
AviscumineCy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy).
BCG vaccineBCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.
NorfluraneNorflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
LevomenolLevomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain...
IpecacAn emetic agent used to induce vomiting in poisoning.
Guar gumNot Annotated
Peanut oilA compound used to lubricate ear wax, as an emollient, and used in laxatives.
Bos taurus gallstoneBos taurus gallstone is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
TurmericTurmeric is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Panax notoginseng rootPanax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Meadowfoam seed oilMeadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Argan oilArgan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Tangerine peelTangerine peel is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Coconut oilCoconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
AmberAmber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Sunflower oilSunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Nelumbo nucifera flowerNelumbo nucifera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Bergamot oilBergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Angelica sinensis rootAngelica sinensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Forsythia suspensa fruitForsythia suspensa fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Saw palmettoSaw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Scutellaria baicalensis rootScutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Palm oilPalm oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Sophora flavescens rootNot Annotated
Lavender oilNot Annotated
Plantago ovata seedNot Annotated
alpha-Conotoxin VC 1.1Investigated for use/treatment in pain (acute or chronic).
EmodinEmodin has been investigated for the treatment of Polycystic Kidney.
Phleum pratense pollenAn extract from Phleum pratense pollen used in allergy testing.
Yellow Fever VaccineYellow Fever Vaccine is indicated for active immunization for the prevention of yellow fever in persons 9 months of age and older in the following categories: Persons Living in or...
Ginkgo bilobaAppears to be effective in: alleviating age-related memory impairment in some elderly people with mild to moderate age-related memory or cognitive impairment; improving cognitive function in healthy young to middle-aged...
VitespenInvestigated for use/treatment in kidney cancer, melanoma, renal cell carcinoma, lymphoma (unspecified), colorectal cancer, and brain cancer.
Polyacrylamide (crosslinked; 2 mole percent bisacrylamide)Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females).
AnfibatideAnfibatide is under investigation in clinical trial NCT01585259 (Anfibatide Phase Ib-IIa Clinical Trial).
ChlorotoxinChlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
VB-201VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).
Pertussis vaccinePertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
TozuleristideTozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Yersinia pestis 195/p antigen (formaldehyde inactivated)Yersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine).
Insulin glargineA modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus.
AdalimumabA monoclonal anti-tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.
InfliximabA monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.
ObiltoxaximabA monoclonal antibody used for prophylaxis or treatment of inhalational anthrax.
Chlorotoxin I-131Investigated for use/treatment in various forms of brain cancer; Malignant Glioma, Glioblastoma Multiforme, GBM, Anaplastic Astrocytoma, Oligo-Astrocytoma, Gliosarcoma
Eucalyptus oilAn ingredient used in a variety of natural health products.
Talimogene laherparepvecA genetically modified virus used to treat recurrent melanoma, or metastatic melanoma.
AlloinNot Annotated
Frangula purshiana barkNot Annotated
beta-Apopicropodophyllinbeta-Apopicropodophyllin is a component of the freshwater plant Micranthemum umbrosum.
AcaciaAn extract from Acacia used in allergy testing.
Maritime pine extractNot Annotated
SolcoserylNot Annotated
LecithinA complex mixture of phospholipids, glycolipids, triglycerides, phosphatidylcholines, phosphatidylethanolamines, and phosphatidylinositols.
Hawthorn leaf with flowerNot Annotated
IMM-101IMM-101 is a heat-inactivated immune-activating mycobacterial product. It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma[A220013,A220018,A220023]. Studies...
Drugs & Drug Targets
DrugTargetType
MenotropinsFollicle-stimulating hormone receptortarget
MenotropinsLutropin-choriogonadotropic hormone receptortarget
Botulinum Toxin Type BVesicle-associated membrane protein 1target
Botulinum Toxin Type BVesicle-associated membrane protein 2target
Botulinum Toxin Type BSynaptotagmin-2target
PancrelipaseDietary fattarget
PancrelipaseDietary proteintarget
PancrelipaseDietary starchtarget
UrofollitropinFollicle-stimulating hormone receptortarget
Antithymocyte immunoglobulin (rabbit)T-cell surface glycoprotein CD1atarget
Antithymocyte immunoglobulin (rabbit)Major histocompatibility complex class I-related gene proteintarget
Antithymocyte immunoglobulin (rabbit)Integrin alpha-Ltarget
Antithymocyte immunoglobulin (rabbit)T-lymphocyte activation antigen CD86target
Antithymocyte immunoglobulin (rabbit)Low affinity immunoglobulin gamma Fc region receptor II-btarget
Antithymocyte immunoglobulin (rabbit)T-cell surface glycoprotein CD4target
Antithymocyte immunoglobulin (rabbit)Integrin beta-1target
Antithymocyte immunoglobulin (rabbit)Integrin alpha-Vtarget
Antithymocyte immunoglobulin (rabbit)Integrin beta-3target
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
BufotenineAmine oxidase [flavin-containing] Aenzyme
CamphorCamphor 5-monooxygenasetarget
CamphorTransient receptor potential cation channel subfamily V member 1target
CamphorTransient receptor potential cation channel subfamily V member 3target
CamphorTransient receptor potential cation channel subfamily A member 1target
CamphorTransient receptor potential cation channel subfamily M member 8target
Ricinoleic AcidCannabinoid receptor 1target
Ricinoleic AcidCannabinoid receptor 2target
Ricinoleic AcidTransient receptor potential cation channel subfamily V member 1target
Choline alfoscerateGanglioside GM2 activatortarget
AncrodFibrinogen alpha chaintarget
RindopepimutEpidermal growth factor receptortarget
AE-94172 kDa type IV collagenasetarget
AE-941Matrix metalloproteinase-9target
AE-941Macrophage metalloelastasetarget
AndrographolideTumor necrosis factortarget
AndrographolideInterleukin-1 betatarget
AndrographolideInterleukin-6target
AndrographolideNuclear factor NF-kappa-B p100 subunittarget
AndrographolideNuclear factor NF-kappa-B p105 subunittarget
LLL-3348Interleukin-10target
ZiconotideVoltage-dependent N-type calcium channel subunit alpha-1Btarget
ZiconotideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
TG4010Mucin-1target
TG4010Interleukin-2target
Sipuleucel-TProstatic acid phosphatasetarget
SerotoninSolute carrier family 22 member 2transporter
SerotoninSodium-dependent serotonin transportertarget
Serotonin5-hydroxytryptamine receptor 2Atarget
Serotonin5-hydroxytryptamine receptor 3Atarget
Serotonin5-hydroxytryptamine receptor 3Btarget
SerotoninSynaptic vesicular amine transportertarget
Soybean oilPeroxisome proliferator-activated receptor alphatarget
Castor oilProstaglandin E2 receptor EP3 subtypetarget
Castor oilProstaglandin E2 receptor EP4 subtypetarget
TurpentineMitogen-activated protein kinase 1target
OpiumDelta-type opioid receptortarget
OpiumKappa-type opioid receptortarget
OpiumMu-type opioid receptortarget
OpiumSerum albumincarrier
OpiumBeta-2-microglobulincarrier
OpiumCytochrome P450 2D6enzyme
OpiumCytochrome P450 3A4enzyme
Capsicum oleoresinTransient receptor potential cation channel subfamily V member 1target
Silicon dioxideMacrophage receptor MARCOtarget
Peppermint oilCytochrome P450 1A2enzyme
Peppermint oilCytochrome P450 3A4enzyme
Clove oilVascular cell adhesion protein 1target
Clove oilC-X-C motif chemokine 10target
Clove oilCollagen alpha-1(I) chaintarget
Clove oilGranulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
Evening primrose oilElongation of very long chain fatty acids protein 5enzyme
Evening primrose oilFatty acid desaturase 1enzyme
Evening primrose oilFatty acid desaturase 2enzyme
SennosidesReverse transcriptase/RNaseHtarget
SennosidesAquaporin-3target
LevomenolSolute carrier organic anion transporter family member 1B1transporter
LevomenolSolute carrier organic anion transporter family member 1B3transporter
IpecacCytochrome P450 2D6enzyme
IpecacCytochrome P450 3A4enzyme
EmodinCasein kinase II subunit alphatarget
EmodinPutative ketoacyl reductasetarget
Emodin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
EmodinAryl hydrocarbon receptortarget
Ginkgo bilobaCytochrome P450 2C9enzyme
Ginkgo bilobaPhospholipase A2, membrane associatedtarget
Ginkgo bilobaSodium-dependent noradrenaline transportertarget
Ginkgo bilobaGlycine receptor subunit alpha-1target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit alpha-1target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit beta-2target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit gamma-2target
Ginkgo bilobaCytochrome P450 3A4enzyme
Insulin glargineInsulin receptortarget
Insulin glargineInsulin-like growth factor 1 receptortarget
Insulin glargineCytochrome P450 1A2enzyme
AdalimumabTumor necrosis factortarget
InfliximabTumor necrosis factortarget
Talimogene laherparepvecHeparan sulfatetarget
Talimogene laherparepvecDNA polymerase catalytic subunittarget
Talimogene laherparepvecDNA polymerase catalytic subunittarget