Complex Mixtures
- Name
- Complex Mixtures
- Accession Number
- DBCAT000109
- Description
Mixtures of many components in inexact proportions, usually natural, such as PLANT EXTRACTS; VENOMS; and MANURE. These are distinguished from DRUG COMBINATIONS which have only a few components in definite proportions.
- Drugs
Drug Drug Description Ziconotide An N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics. Ferumoxsil Not Annotated Rice bran oil Rice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It... Linseed oil Linseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic... Sennosides A laxative used to treat constipation. Ginkgo biloba A herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders. Talimogene laherparepvec A genetically modified virus used to treat recurrent melanoma, or metastatic melanoma. Maritime pine extract A plant extract in nutritional supplements for healthy hair, skin, and nails. Ancrod An anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country. Serotonin For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product. Cenderitide Cenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall. Cilengitide Cilengitide has been used in trials studying the treatment of Sarcoma, Gliomas, Lymphoma, Leukemia, and Lung Cancer, among others. Anfibatide Anfibatide is under investigation in clinical trial NCT01585259 (Anfibatide Phase Ib-IIa Clinical Trial). Menotropins A purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility. Botulinum toxin type B A purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea. Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Infliximab A monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. Pancrelipase A purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis. Antithymocyte immunoglobulin (rabbit) A purified form of rabbit anti-thymocyte antibodies used for immunosuppression in patients receiving kidney transplants. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Ethiodized oil A contrast agent used in imaging procedures. St. John's Wort An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety. Ephedra sinica root An alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest. Ginseng A herbal supplement used in many health products. Bufotenine A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a... Camphor A compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed. G17DT Immunogen Intended for the treatment of various forms of cancer. BZL101 Investigated for use/treatment in breast cancer. INGN 201 Investigated for use/treatment in bladder cancer, brain cancer, breast cancer, esophageal cancer, head and neck cancer, lung cancer, oral cavity cancer, ovarian cancer, and prostate cancer. INGN 225 Investigated for use/treatment in breast cancer, head and neck cancer, and lung cancer. Obiltoxaximab A monoclonal antibody used for prophylaxis or treatment of inhalational anthrax. Rindopepimut Investigated for use/treatment in brain cancer. Neovastat Investigated for use/treatment in kidney cancer, lung cancer, macular degeneration, multiple myeloma, prostate cancer, and psoriasis and psoriatic disorders. SRP 299 Investigated for use/treatment in asthma, atopic dermatitis, and pediatric atopic dermatitis indications. TA-NIC Investigated for use/treatment in tobacco dependence. Chlorotoxin I-131 Investigated for use/treatment in various forms of brain cancer; Malignant Glioma, Glioblastoma Multiforme, GBM, Anaplastic Astrocytoma, Oligo-Astrocytoma, Gliosarcoma alpha-Conotoxin VC 1.1 Investigated for use/treatment in pain (acute or chronic). LLL-3348 Investigated for use/treatment in psoriasis and psoriatic disorders. GI-5005 Investigated for use/treatment in hepatitis (viral, C). Vitespen Investigated for use/treatment in kidney cancer, melanoma, renal cell carcinoma, lymphoma (unspecified), colorectal cancer, and brain cancer. Calfactant A lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants. TG4010 Investigated for use/treatment in breast cancer, renal cell carcinoma, prostate cancer, and lung cancer. Sipuleucel-T An autologous cellular immunotherapy indicated for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer. Beractant A pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants. Batroxobin No approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously. Podophyllin A cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata). Poractant alfa A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Chorionic Gonadotropin (Human) A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women. Antilymphocyte immunoglobulin (horse) A primarily IgG immune globulin used to manage allograft rejection in renal transplant patients. Soybean oil An oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency. Safflower oil No approved therapeutic indications. Methyl salicylate A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons. Rotavirus vaccine Rotarix is indicated for prevention of rotavirus gastroenteritis caused by G1, G3, G4, and G9 types in infants aged 6-24 weeks [FDA Label]. Rotateq is indicated for the prevention of... Rabies virus inactivated antigen, A Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the... Varicella zoster vaccine (live/attenuated) Zostavax vaccine is indicated for the prevention of herpes zoster (shingles) in immunocompetent adults aged 50 years and older. Varivax vaccine is indicated for active immunization for the prevention of... House dust An extract from House dust used in allergy testing. Phleum pratense pollen An extract from Phleum pratense pollen used in allergy testing. Acacia An extract from Acacia used in allergy testing. Karaya gum An extract from Karaya gum used in allergy testing. Clostridium tetani toxoid antigen (formaldehyde inactivated) Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention... Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) Not Annotated Tragacanth An extract from Tragacanth used in allergy testing. Clove An extract from Clove used in allergy testing. Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated) Not Annotated Yellow fever vaccine Yellow Fever Vaccine is indicated for active immunization for the prevention of yellow fever in persons 9 months of age and older in the following categories: Persons Living in or... Carob An extract from Carob used in allergy testing. Hepatitis A Vaccine A live attenuated vaccine against infection with the Hepatitis A virus. Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects... Anthrax vaccine A vaccine indicated for the pre- and post-exposure prophylaxis treatment of diseases caused by exposure to Bacillus anthracis Coal tar Relieving itching, irritation, redness, dryness, scaling, and flaking of the skin caused by psoriasis, seborrhea, or eczema. Plantago seed An ingredient used in a variety of natural health products. Castor oil An ingredient used in a variety of natural health products. Eucalyptus oil An ingredient used in a variety of natural health products. Turpentine A medication used to treat minor aches and pains of muscles and joints. Opium A medication used to treat moderate to severe pain. Capsicum oleoresin A medication used to treat minor aches and pains of muscles and joints. Silicon dioxide An ingredient found in a variety of supplements and vitamins. Pectin Pectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary... Rosin An extract from Rosin used in allergy testing. Sesame oil Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic... Peppermint oil An ingredient used in a variety of natural health products and is not an approved medication. Tea tree oil Indicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications. Benzoin resin A compound used to protect small wounds or canker sores. Tolu balsam Not Annotated Borage oil Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as... Clove oil Clove oil is primarily indicated in conditions like colic, flatulence, and toothache . Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Balsam of Peru Balsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of... Myrrh FDA approved only for use in food. Historically used for indigestion, ulcers, colds, cough, asthma, bronchial congestion, arthritic pain, cancer, leprosy, and syphilis. It is also used orally as a... Human varicella-zoster immune globulin A solution of antibodies used for post exposure prophylaxis of varicella infections in high risk populations, as well as to reduce the severity of infections. Hepatitis B Vaccine (Recombinant) A solution of Hepatitis B surface antigen used to immunize patients against Hepatitis B. Bombesin Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and... Carbon black Carbon black has been used in trials studying Atopic Hypersensitivity and Hypersensitivity, Immediate. Tecemotide Tecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung. Aviscumine Cy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy). BCG vaccine A vaccine indicated in the prevention of tuberculosis and the treatment of non-invasive urothelial bladder cancer. Neosaxitoxin Neosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic). Levomenol Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain... Vitex agnus-castus fruit extract A herbal product used to treat an irregular menstrual period, premenstrual symptoms, and mastodynia Horse chestnut A plant extract indicated in the treatment of venous insufficiency and other disorders caused by poor circulation. Valerian A plant used in some non-prescription natural health products. Ipecac An emetic agent used to induce vomiting in poisoning. Guar gum Not Annotated Axicabtagene ciloleucel A CAR T-cell therapy used to treat adults with large B-cell lymphomas and follicular lymphoma. Remestemcel-L Indicated for in the management of acute Graft versus Host Disease (aGvHD) in pediatric patients. Acute GvHD should be refractory to treatment with systemic corticosteroid therapy and/or other immunosuppressive agents.... Black cohosh A herbal product indicated in the symptomatic treatment of menopause. Typhoid vaccine A vaccine used to prevent typhoid. Bilberry Not Annotated Echinacea purpurea flowering top Not Annotated Echinacea purpurea Not Annotated Bos taurus gallstone Bos taurus gallstone is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug. Centella asiatica Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Calendula officinalis flower Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Rosemary Rosemary is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Turmeric Turmeric is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Phellinus linteus mycelium Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Panax ginseng whole Panax ginseng whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Rehmannia glutinosa root Rehmannia glutinosa root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Arnica montana Arnica montana is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Eleuthero Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Panax notoginseng root Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Tribulus terrestris fruit Tribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Green tea leaf Green tea leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Meadowfoam seed oil Meadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Argan oil Argan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Tangerine peel Tangerine peel is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Amber Amber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Chamaemelum nobile flower Chamaemelum nobile flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Sunflower oil Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Nelumbo nucifera flower Nelumbo nucifera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Bergamot oil Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Angelica sinensis root Angelica sinensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Salvia miltiorrhiza root Salvia miltiorrhiza root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Prunus armeniaca seed Prunus armeniaca seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Arnica montana flower Arnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Forsythia suspensa fruit Forsythia suspensa fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Platycodon grandiflorus root Platycodon grandiflorus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Chamomile Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Saw palmetto Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Scutellaria baicalensis root Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Milk thistle Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Palm oil Palm oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Vibrio cholerae CVD 103-HgR strain live antigen A live, attenuated vaccine indicated for active immunization against disease caused by Vibrio cholerae serogroup O1. Sophora flavescens root Not Annotated Lavender oil Not Annotated Plantago ovata seed A plant extract indicated in the treatment of occasional constipation. Sambucus nigra flower Not Annotated Willow bark Not Annotated Smallpox (Vaccinia) Vaccine, Live The live antigen of the New York City Board of Health strain of Vaccinia is indicated (within the ACAM2000 formulation) for active immunization against smallpox disease in patients determined to... Olea europaea leaf Not Annotated Polygala senega root Not Annotated Dengue tetravalent vaccine, live Not Annotated Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females). Belapectin Belapectin is under investigation in clinical trial NCT02575404 (GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients). Chlorotoxin Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma). Pertussis vaccine Pertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy). Tozuleristide Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery). Yersinia pestis 195/p antigen (formaldehyde inactivated) Yersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine). Onasemnogene abeparvovec A gene therapy used to treat neonatal and infant patients with spinal muscular atrophy caused by bi-allelic mutations in the survival motor neuron 1 (SMN1) gene. beta-Apopicropodophyllin beta-Apopicropodophyllin is a component of the freshwater plant Micranthemum umbrosum. AstraZeneca COVID-19 Vaccine A two-dose replication-deficient adenovirus vector vaccine used to prevent COVID-19 caused by SARS-CoV-2. INO-4800 INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that... BNT162b1 SARS-CoV-2 Vaccine BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding... Tozinameran An mRNA vaccine for the prevention of COVID-19 caused by the SARS-CoV-2 virus. Anise oil Not Annotated Solcoseryl A component of calf blood indicated to improve healing of the skin, mouth, or cornea. VPM1002 The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. This recombinant... BBIBP-CorV BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in... Nuvaxovid A recombinant spike (S) protein vaccine for the prevention of COVID-19 caused by SARS-CoV-2. Lecithin Fatty substances commonly found in nutritional supplements. Hawthorn leaf with flower Not Annotated IMM-101 IMM-101 is a heat-inactivated immune-activating mycobacterial product. It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma[A220013,A220018,A220023]. Studies... Janssen COVID-19 Vaccine An adenovirus-based vaccine used for active immunization against COVID-19 caused by SARS-CoV-2 infection. Senna leaf A stimulant laxative indicated in the treatment of occasional constipation. Cajuput oil An ingredient used in topical products for mild analgesia. Bizalimogene ralaplasmid Bizalimogene ralaplasmid is under investigation in clinical trial NCT03499795 (VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And/or HPV-18 Related Anal or Anal/peri-anal, High Grade... Pidacmeran Pidacmeran is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults). BNT-162A1 BNT-162A1 is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults). SARS-CoV-2 vaccine SARS-CoV-2 vaccine is an adjuvanted recombinant protein-based COVID-19 vaccine candidate being developed collaboratively by GlaxoSmithKline (GSK) and Sanofi[L30405, L30410, L30415]. This vaccine candidate is composed of a spike protein antigen... EpiVacCorona EpiVacCorona Vaccine, developed by the Vektor State Research Center of Virology and Biotechnology in Russia, is based on peptide-antigens that facilitate immunity to the SARS-CoV-2 virus . It is currently... OM85 OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity. Gentiana lutea extract A medication used to treat bloating and gas. Wheat germ oil Not Annotated Pygeum africanum bark A plant extract indicated in the symptomatic treatment of prostatic hypertrophy. Frankincense Not Annotated Paeonia lactiflora root Not Annotated Citronella oil Not Annotated Vitis vinifera seed Not Annotated Thyme oil Not Annotated Gastrodia elata whole Not Annotated Juniper tar Not Annotated Birch bark extract A herbal medicinal product used to treat partial thickness wounds. Virulizin Not Available Algenpantucel-L Not Annotated Leuvectin Leuvectin (formerly known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE). Onamelatucel-L Not Annotated Gemogenovatucel-T Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine. Furin is a convertase involved in the activation of TGFβ-1 and TGFβ-2. Gemogenovatucel-T is being... Incomplete Freund's adjuvant Not Annotated GI-6207 Not Annotated Picibanil Not Annotated Trastuzumab A monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers. Picrotoxin Used internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates. Andrographolide Investigated for use/treatment in ulcerative colitis. Liquidambar styraciflua resin Not Annotated Glycyrrhiza glabra Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Ephedra sinica stem Not Annotated Modified vaccinia ankara A live, non-replicating orthopoxvirus vaccine used to prevent smallpox, monkeypox, and other diseases caused by vaccinia virus. SCB-2019 SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The... CoronaVac CoronaVac, previously known as PiCoVacc, is a SARS-CoV-2 purified, inactivated, and adsorbed vaccine candidate developed by SinoVac Biotech Corporation . It was developed by propagating the SARS-CoV-2 CN2 strain inside... CVnCoV Vaccine The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate... BBV152 BBV152 is a vaccine candidate created by the Indian Council of Medical Research (ICMR). The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and... Rocakinogene sifuplasmid Rocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma (GBM)). CoVac-1 Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein . It is... UB-612 The UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components . The vaccine... Betibeglogene autotemcel A hematopoietic stem cell-based gene therapy used in the treatment of β-thalassemia in adult and pediatric patients who require regular red blood cell transfusions. Famtozinameran A component of a bivalent COVID-19 mRNA vaccine encoding the viral spike protein of Omicron variant lineages BA.4 and BA.5. Nix-0699 Not Annotated Tubimod Not Available Remune Not Available GsMtx-4 GsMtx-4 is a peptide found in tarantula venom that inhibits mechanosensitive ion channel (MSC) activity. Mycobacterium w. Vaccine The Mycobacterium w (M.w) vaccine is a heat-killed suspension derived from a non-pathogenic mycobacterium: mycobacterium indicus pranii. As an immunotherapy, M.w is used against leprosy; the compound also shares antigens... - Drugs & Drug Targets