Amino Acids, Aromatic
- Amino Acids, Aromatic
- Accession Number
Amino acids containing an aromatic side chain.
Drug Drug Description Phenylalanine An amino acid commonly found as a component of total parenteral nutrition. Tyrosine An amino acid commonly found as a component in total parenteral nutrition. Tryptophan An amino acid commonly found as a component of total parenteral nutrition. Levothyroxine A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. Dextrothyroxine A thyroid hormone used to treat hyperlipidemia. Nateglinide A meglitinide used to treat non insulin dependent diabetes mellitus. Metyrosine A tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma. Tirofiban A platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome. Methyldopa A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises. Melphalan An alkylating antineoplastic agent used for high-dose conditioning prior to hematopoietic stem cell transplant in patients with multiple myeloma. Levodopa A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. Liotrix May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... Oxitriptan A naturally occurring amino acid that is used to manage post-hypoxic myoclonus. N,O-didansyl-L-tyrosine Not Available L-tyrosinamide Not Available 3-Tyrosine Not Available 4-Iodo-L-phenylalanine Not Available Batimastat Not Available Phenylalanylamide Not Available 6-hydroxydopa quinone Not Available Paratoulene phosphate Not Available Phenyldehydroalanine Not Available CDP323 Investigated for use/treatment in multiple sclerosis. LX1031 Irritable bowel syndrome (IBS) and other gastrointestinal disorders WX-UK1 Investigated for use/treatment in solid tumors. GW-559090 Investigated for use/treatment in asthma and allergic rhinitis. Etilevodopa Investigated for use/treatment in parkinson's disease. Eluxadoline A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. N-acetyltyrosine An amino acid used in total parenteral nutrition. Lifitegrast A medication used to treat dry eye disease. Telotristat ethyl A tryptophan hydroxylase inhibitor used to treat carcinoid syndrome. 3,5-diiodothyropropionic acid DITPA has been investigated in Congestive Heart Failure. Indoximod Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others. Macimorelin A medication used to treat adult growth hormone deficiency. Tiropramide A medication indicated in the treatment of spastic pain of the gastrointestinal system. Melevodopa A methyl ester of levodopa indicated in combination with carbidopa for the treatment of Parkinson's disease. Telotristat A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat. 5-fluorotryptophan 5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy. GS-9191 GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts). Fluorodopa (18F) Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes... Solriamfetol Solriamfetol is indicated for treatment of daytime sleepiness associated with obstructive sleep apnea and narcolepsy, but is not a treatment for the underlying airway obstruction in apnea patients[FDA Label][A176534,A176744]. p-Benzoyl-L-phenylalanine Not Available 3-nitro-L-tyrosine Not Available Tryptophanamide Not Available methyl L-phenylalaninate Not Available MK-0668 Not Annotated TRC150094 TRC150094 is under investigation in clinical trial NCT03254446 (Safety and Efficacy Study of TRC150094 to Improve the CV Risk in Subjects With Diabetes, Dyslipidemia and Hypertension). Denagliptin Denagliptin is under investigation in clinical trial NCT00387972 (Study of Denagliptin in Subjects With Type 2 Diabetes Mellitus (T2DM)). Racemetyrosine Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer). Melphalan flufenamide A melphalan prodrug used to treat relapsed or refractory multiple myeloma. Tetraiodothyroacetic acid Not Available Tiratricol A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome. Rupintrivir Investigated for use/treatment in viral infection. Nordazepam A benzodiazepine indicated in the treatment of insomnia. Carotegrast methyl Carotegrast methyl is under investigation in clinical trial NCT03531892 (A Study to Evaluate the Safety and Efficacy of AJM300 in Participants With Active Ulcerative Colitis).
- Drugs & Drug Targets