Carotegrast methyl

DB16119InvestigationalSmall molecule

Carotegrast methyl is under investigation in clinical trial NCT03531892 (A Study to Evaluate the Safety and Efficacy of AJM300 in Participants With Active Ulcerative Colitis).

Mechanism: Pharmacologically active on Integrin alpha-4
Curator reviewed
Formula / weight: C₂₈H₂₆Cl₂N₄O₅ · 569.44 g/mol (avg)

Resolves to

Compound

UNIIOYK17DYO9MCAS401905-67-7

Structure

InChIKeyMMHHPKCJJIFLBQ-QFIPXVFZSA-NSMILESCOC(=O)[C@H](CC1=CC=C(C=C1)N1C(=O)N(C)C2=C(C=C(C=C2)N(C)C)C1=O)NC(=O)C1=C(Cl)C=CC=C1Cl

Targets

P13612ITGA4

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Carotegrast methyl, and which of those have an active Phase 3 trial?

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