- Nootropic Agents
- Accession Number
Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.
Drug Drug Description Choline A nutrient found in a wide variety of vitamins including pre-natal formulations. Tacrine For the palliative treatment of mild to moderate dementia of the Alzheimer's type. Galantamine A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. Nicergoline For the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration. Donepezil An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia. Ergoloid mesylate A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. Aniracetam Compound with anti-depressive properties used as a mental performance enhancer. Cutamesine Investigated for use/treatment in strokes and depression. Acetylcarnitine Acetylcarnitine is not approved for any indication in the United states and Canada, but it is approved and indicated in Italy for cerebrovascular disorders, mental function disorders, peripheral nerve disorders,... Piracetam Indicated in adult patients suffering from myoclonus of cortical origin, irrespective of aetiology, and should be used in combination with other anti-myoclonic therapies . Omega-3-acid ethyl esters A mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia. Etiracetam Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)). Vinpocetine Vinpocetine has been investigated for the treatment of Epilepsy. Nefiracetam Nefiracetam has been used in trials studying the treatment of Alzheimer's Disease. Oxiracetam Not Annotated Meclofenoxate Not Annotated Hopantenic acid Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal... Citicoline Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnostic of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar... GSK-239512 GSK-239512 is under investigation in clinical trial NCT00474513 (An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.).
- Drugs & Drug Targets