Nootropic Agents
- Name
- Nootropic Agents
- Accession Number
- DBCAT000278
- Description
Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.
- Drugs
Drug Drug Description Acetylcarnitine An acetylated form of the amino acid derivative L-carnitine that assists in mitochondrial fatty acid metabolism. It is under investigation as a treatment for numerous conditions, including neuropathy, depression, and dementia. Aniracetam A nootropic drug used to ameliorate memory and attention disturbances accompanying cerebrovascular diseases and degenerative brain disorders. Cerebrolysin A proteolytic protein indicated in the treatment of cerebrovascular disorders. Choline A nutrient found in a wide variety of vitamins including pre-natal formulations. Citicoline An endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects. Cutamesine Investigated for use/treatment in strokes and depression. Donepezil An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia. Ergoloid mesylate A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. Etiracetam Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)). Galantamine A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. Hopantenic acid Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal... Meclofenoxate Not Annotated Nefiracetam Nefiracetam has been used in trials studying the treatment of Alzheimer's Disease. Nicergoline An ergot derivative use for the treatment of symptoms associated with cerebrovascular abnormalities. Omega-3-acid ethyl esters A mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia. Oxiracetam Not Annotated Piracetam A nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer. Tacrine An anticholinesterase drug used for the management of Alzheimer's disease symptoms. Taltirelin Taltirelin is a small molecule drug. The usage of the INN stem '-tirelin' in the name indicates that Taltirelin is a thyrotropin releasing hormone analogue. Taltirelin has a monoisotopic molecular... Tilavonemab Not Annotated Vinpocetine A synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease. - Drugs & Drug Targets