Amino Acids, Diamino

Name
Amino Acids, Diamino
Accession Number
DBCAT000279
Description

Amino acids with side chains that are positively charged at physiological pH.

Drugs
DrugDrug Description
ArginineAn amino acid commonly found as a component of total parenteral nutrition.
L-GlutamineAn amino acid commonly found as a component in total parenteral nutrition.
CitrullineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
AsparagineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
OrnithineAn amino acid commonly found as a component in total parenteral nutrition.
LysineAn amino acid commonly found as a component of total parenteral nutrition.
2,6-Diaminopimelic AcidNot Available
CystineAn oxidated derivative of the amino acid cysteine found in various nutritional products, acne treatments, and creams to treat cervical injury or inflammation.
N-(Phosphonoacetyl)-L-OrnithineNot Available
D-GlutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of...
N(G)-IminoethylornithineNot Available
TalotrexinInvestigated for use/treatment in solid tumors, lung cancer, leukemia (unspecified), and leukemia (lymphoid).
EflornithineAn ornithine decarboxylase inhibitor used to prevent relapse of high-risk neuroblastoma in pediatric and adult patients
FasitibantFasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).
ArgatrobanA synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
N,N-dimethylarginineAsymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which...
Epsilon-N-methyllysineNot Available
N-acetyl-L-arginineNot Available
Symmetric dimethylarginineNot Available
IsoglutamineNot Available
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNot Available
RWJ-51084Not Available
ThiocitrullineNot Available
L-homoarginineNot Available
TrimethyllysineNot Available
AceglutamideNot Available
N(2)-(2-carboxyethyl)-L-arginineNot Available
L-SaccharopineNot Available
NitroarginineAn inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in...
beta-HydroxyasparagineNot Available
DansyllysineNot Available
PalifosfamideInvestigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.
ClonixinAn NSAID used to relieve pain associated with arthritis, migraines, and various soft tissue disorders.
TilarginineTilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.
AstodrimerAstodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
N-omega-nitro-L-arginine methyl esterL-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
ProglumideNot Annotated
Piflufolastat F 18A radiopharmaceutical diagnostic agent used with PET to image PSMA-positive lesions for the diagnosis of metastatic or recurrent prostate cancer.
CiraparantagCiraparantag is under investigation in clinical trial NCT01826266 (Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban).
Arginine aspartateAn ingredient in products indicated to treat exhaustion during stress, endurance sports, or in the elderly.
PhenylacetylglutamineNot Annotated
L-arginineNot Annotated
HiltonolNot Available
Heme arginateNot Available
NacystelynNot Annotated
Drugs & Drug Targets
DrugTargetType
ArginineCationic amino acid transporter 3target
ArginineAntizyme inhibitor 2target
ArginineArgininosuccinate lyasetarget
ArginineNitric oxide synthase, inducibletarget
ArginineHigh affinity cationic amino acid transporter 1target
ArginineArginase-2, mitochondrialtarget
ArginineCationic amino acid transporter 4target
ArginineArgininosuccinate synthasetarget
ArginineNitric oxide synthase 3target
ArginineOrganic cation/carnitine transporter 2transporter
ArginineMonocarboxylate transporter 10transporter
ArginineSolute carrier family 22 member 4transporter
L-GlutamineCTP synthase 1target
L-GlutamineAmidophosphoribosyltransferasetarget
L-GlutamineGlutamine synthetasetarget
L-GlutamineMonocarboxylate transporter 10transporter
L-GlutamineCoagulation factor XIII A chainenzyme
L-GlutamineGlutaminase kidney isoform, mitochondrialenzyme
L-GlutamineGlutaminase liver isoform, mitochondrialenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 2enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 5enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 6enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Kenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 4enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Eenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Zenzyme
L-GlutamineSodium-coupled neutral amino acid transporter 3transporter
L-GlutamineNeutral amino acid transporter B(0)transporter
L-GlutamineGMP synthase [glutamine-hydrolyzing]enzyme
L-GlutamineAsparagine synthetase [glutamine-hydrolyzing]enzyme
L-GlutamineKynurenine--oxoglutarate transaminase 1enzyme
L-GlutaminePhosphoribosylformylglycinamidine synthaseenzyme
L-GlutamineGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrialenzyme
L-GlutamineGlutamine--fructose-6-phosphate aminotransferase [isomerizing] 2enzyme
L-GlutamineMultifunctional protein CADenzyme
L-GlutamineGlutamine--tRNA ligaseenzyme
L-GlutamineGlutamine-dependent NAD(+) synthetaseenzyme
L-GlutamineLarge neutral amino acids transporter small subunit 2transporter
L-GlutamineSodium-coupled neutral amino acid symporter 1transporter
L-GlutamineSodium-coupled neutral amino acid symporter 2transporter
L-GlutamineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
L-GlutamineY+L amino acid transporter 1transporter
L-GlutamineY+L amino acid transporter 2transporter
L-GlutamineLarge neutral amino acids transporter small subunit 1transporter
L-Glutamineb(0,+)-type amino acid transporter 1transporter
CitrullineNitric oxide synthase 3target
CitrullineArgininosuccinate synthasetarget
CitrullinePutative hydrolase DDAH2target
CitrullineN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
CitrullineOrnithine transcarbamylase, mitochondrialtarget
CitrullineNitric oxide synthase 1target
CitrullineNitric oxide synthase, inducibletarget
CitrullineProtein-arginine deiminase type-4target
CitrullineProtein-arginine deiminase type-6target
CitrullineProtein-arginine deiminase type-1target
CitrullineProtein-arginine deiminase type-3target
CitrullineProtein-arginine deiminase type-2target
CitrullineSolute carrier family 22 member 6transporter
AsparagineNeutral amino acid transporter B(0)target
AsparagineAsparagine synthetase [glutamine-hydrolyzing]target
AsparagineAsparagine--tRNA ligase, cytoplasmictarget
AsparagineIsoaspartyl peptidase/L-asparaginasetarget
AsparagineAsparaginyl-tRNA synthetasetarget
AsparagineMonocarboxylate transporter 10transporter
AsparagineSodium-coupled neutral amino acid transporterstarget
OrnithineOrnithine aminotransferase, mitochondrialtarget
OrnithineOrnithine transcarbamylase, mitochondrialtarget
OrnithineArginase-1target
OrnithineOrnithine decarboxylase antizyme 1target
OrnithineCationic amino acid transporter 2target
OrnithineMitochondrial ornithine transporter 2target
OrnithineHigh affinity cationic amino acid transporter 1target
OrnithineArginase-2, mitochondrialtarget
OrnithineMitochondrial ornithine transporter 1target
OrnithineGlycine amidinotransferase, mitochondrialtarget
LysineHigh affinity cationic amino acid transporter 1target
LysineCationic amino acid transporter 4target
LysineCationic amino acid transporter 3target
LysineCationic amino acid transporter 2target
LysineLysine--tRNA ligasetarget
LysineMonocarboxylate transporter 10transporter
LysineSolute carrier family 22 member 4transporter
2,6-Diaminopimelic AcidUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligasetarget
2,6-Diaminopimelic AcidMeso-diaminopimelate D-dehydrogenasetarget
CystineCystine/glutamate transportertarget
CystineCystinosintarget
CystineMonocarboxylate transporter 10transporter
Cystineb(0,+)-type amino acid transporter 1transporter
CystineAmino acid transporter heavy chain SLC3A1transporter
N-(Phosphonoacetyl)-L-OrnithineOrnithine transcarbamylase, mitochondrialtarget
D-GlutamineGlutamate racemasetarget
N(G)-IminoethylornithineNitric oxide synthase 3target
N(G)-IminoethylornithineNitric oxide synthase, inducibletarget
N(G)-IminoethylornithineNitric oxide synthase 1target
TalotrexinFolate receptor alphatarget
EflornithineOrnithine decarboxylasetarget
FasitibantB2 bradykinin receptortarget
ArgatrobanProthrombintarget
ArgatrobanCytochrome P450 3A4enzyme
ArgatrobanCytochrome P450 3A5enzyme
ArgatrobanAlbumincarrier
Argatrobanalpha1-acid glycoproteincarrier
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenAlbumincarrier
KetoprofenATP-binding cassette sub-family C member 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenOrganic anion transporter 3transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1A1enzyme
N,N-dimethylarginineNitric oxide synthase, inducibletarget
N,N-dimethylarginineNitric oxide synthase 3target
N-acetyl-L-arginineClavaminate synthase 1target
Symmetric dimethylarginineHaloalkane dehalogenasetarget
IsoglutamineATP synthase subunit btarget
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNitric oxide synthase 3target
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNitric oxide synthase oxygenasetarget
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNitric oxide synthase, inducibletarget
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineArginase-1target
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNitric oxide synthase 1target
RWJ-51084Serine protease 1target
ThiocitrullineNitric oxide synthase, inducibletarget
L-homoarginineNitric oxide synthase 3target
TrimethyllysineCytochrome ctarget
TrimethyllysineCalmodulin-2target
TrimethyllysineCalmodulin-3target
TrimethyllysineCalmodulintarget
Aceglutamideo-succinylbenzoate synthasetarget
L-SaccharopineAlpha-aminoadipic semialdehyde synthase, mitochondrialtarget
NitroarginineNitric oxide synthase 3target
NitroarginineNitric oxide synthase 1target
beta-HydroxyasparagineMannan-binding lectin serine protease 2target
DansyllysineImmunoglobulin heavy constant alpha 2target
PalifosfamideDNA (cytosine-5)-methyltransferase 1target
TilarginineNitric oxide synthase 3target
AstodrimerEnvelope glycoprotein gp160target
N-omega-nitro-L-arginine methyl esterNitric oxide synthase 3target
ProglumideCholecystokinin receptor type Atarget
Piflufolastat F 18Glutamate carboxypeptidase 2target