Fatty Acids, Unsaturated
- Name
- Fatty Acids, Unsaturated
- Accession Number
- DBCAT000300
- Description
FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds.
- Drugs
Drug Drug Description Travoprost A prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension. Latanoprost An isopropyl ester prodrug used to treat increased intraocular pressure. Bimatoprost A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. Misoprostol A prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers and to terminate pregnancies. Unoprostone A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents. Tafluprost An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Omega-3-acid ethyl esters A mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia. Gefarnate Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. Omega-6 fatty acids There are no current pharmacotherapeutic products based on omega-6 fatty acids. Alprostadil A prostaglandin E1 agonist used for the treatment of erectile dysfunction and as an adjunct for its diagnosis. Palmitoleic Acid Not Available Cobiprostone Investigated for use/treatment in cystic fibrosis. Gemeprost A prostaglandin E1 analogue used for cervical dilation and, in combination with mifepristone, for pregnancy termination. Limaprost An oral prostaglandin E1 analogue used to improve symptoms associated with thromboangiitis obliterans, acquired lumbar spinal canal stenosis, and other ischemic conditions. Omega-3 fatty acids An ingredient found in a variety of supplements and vitamins. Gondoic acid Not Annotated alpha-Linolenic acid A polyunsaturated omega-3 fatty acid found in many supplements. Dihomo-gamma-linolenic acid For nutritional supplementation, also for treating dietary shortage or imbalance Icosapent A polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements. Treprostinil A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol. Carboprost tromethamine A prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective. Dinoprostone A prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. Lubiprostone A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. Iloprost A synthetic prostacyclin analog used to treat pulmonary arterial hypertension (PAH) and frostbites. Dinoprost tromethamine Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities... Epoprostenol A vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure. Prostaglandin D2 The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important... Prostaglandin B2 Not Available Methoxy arachidonyl fluorophosphonate Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid... Ricinoleic acid Not Available Doconexent An omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. Prostaglandin G2 A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] Oleic Acid A naturally occurring fatty acid with antibacterial properties added to a variety of drug products. Arachidonic Acid A natural fatty acid that plays an essential role in physiological homeostases, such as repair and growth of cells. cis-Vaccenic acid Not Available Oleoyl-estrone For the treatment of obesity. Beraprost For the treatment of pulmonary hypertension. Ethanolamine oleate A mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes. Leukotriene C4 The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates... Icosapent ethyl An ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. Undecylenic acid An antifungal used to treat tinea species infections. Borage oil Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as... Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Fenprostalene Not Annotated Luprostiol Not Annotated Prostalene Analog of prostaglandin F2 alpha. Cloprostenol Not Annotated Fluprostenol Not Annotated Latanoprostene bunod A prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma. Leukotriene D4 Leukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis. Sulprostone A prostaglandin analogue used to treat post-partum hemorrhaging, induce medical abortion, and induce labour in instances of in utero fetal death. Dinoprost A medication used to induce a second trimester abortion. Leukotriene B4 Leukotriene B4 has been used in trials studying the treatment of HIV Infections. Resolvin E1 Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers). Enprostil Not Annotated Gamolenic acid An ingredient found in a variety of nutritional products. Linoleic acid Not Annotated Edasalonexent Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes). CXA-10 CXA-10 is under investigation in clinical trial NCT03422510 (FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)). Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). alpha-Hydroxylinoleic acid alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study). Ecraprost Ecraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease). Oleic monoethanolamide Not Available Arachidonyltrifluoromethane Specific inhibitor of phospholipase A2. Incomplete Freund's adjuvant Not Annotated TP-252 TP-252 consists of magnesium L-lysinate bis-eicosapentaenoate, an ionizable salt of eicosapentaenoic acid (EPA), currently being investigated to treat familial adenomatous polyposis. Epeleuton Not Annotated Idroxioleic acid Not Annotated AP-001 Not Annotated AVX-001 AVX-001 is under investigation in clinical trial NCT05164393 (Phase I/iia Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment... Enisoprost Not Annotated Carboprost Not Annotated Latanoprost acid Not Annotated - Drugs & Drug Targets