Fatty Acids, Unsaturated
- Fatty Acids, Unsaturated
- Accession Number
FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds.
Drug Drug Description alpha-Linolenic acid A polyunsaturated omega-3 fatty acid found in many supplements. Dihomo-gamma-linolenic acid For nutritional supplementation, also for treating dietary shortage or imbalance Icosapent A polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements. Travoprost A prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension. Treprostinil A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol. Carboprost tromethamine A prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective. Latanoprost An isopropyl ester prodrug used to treat increased intraocular pressure. Alprostadil A medication used to treat erectile dysfunction. Bimatoprost A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. Dinoprostone A prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. Misoprostol A prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers. Lubiprostone A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. Iloprost A synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH). Dinoprost tromethamine Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities... Epoprostenol A vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure. Prostaglandin B2 Not Available Ricinoleic acid Not Available Prostaglandin G2 A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] Oleic Acid A naturally occurring fatty acid with antibacterial properties added to a variety of drug products. Palmitoleic Acid Not Available Arachidonic Acid A natural fatty acid that plays an essential role in physiological homeostases, such as repair and growth of cells. Oleoyl-estrone For the treatment of obesity. Beraprost For the treatment of pulmonary hypertension. Cobiprostone Investigated for use/treatment in cystic fibrosis. Ethanolamine oleate A mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Unoprostone A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents. Tafluprost An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Leukotriene C4 The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates... Icosapent ethyl An ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia. Gemeprost A prostaglandin E1 analogue used for cervical dilation and, in combination with mifepristone, for pregnancy termination. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. Limaprost An oral prostaglandin E1 analogue used to improve symptoms associated with thromboangiitis obliterans, acquired lumbar spinal canal stenosis, and other ischemic conditions. Omega-3-acid ethyl esters A mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia. Undecylenic acid An antifungal used to treat tinea species infections. Omega-3 fatty acids An ingredient found in a variety of supplements and vitamins. Borage oil Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as... Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Fenprostalene Not Annotated Luprostiol Not Annotated Prostalene Analog of prostaglandin F2 alpha. Cloprostenol Not Annotated Fluprostenol Not Annotated Latanoprostene bunod A prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma. Leukotriene D4 Leukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis. Gefarnate Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. Sulprostone A prostaglandin analogue used to treat post-partum hemorrhaging, induce medical abortion, and induce labour in instances of in utero fetal death. Dinoprost A medication used to induce a second trimester abortion. Leukotriene B4 Leukotriene B4 has been used in trials studying the treatment of HIV Infections. Resolvin E1 Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers). Omega-6 fatty acids There are no current pharmacotherapeutic products based on omega-6 fatty acids. Enprostil Not Annotated Gamolenic acid An ingredient found in a variety of nutritional products. Gondoic acid Not Annotated Linoleic acid Not Annotated cis-Vaccenic acid Not Available Prostaglandin D2 The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important... Doconexent An omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. Methoxy arachidonyl fluorophosphonate Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid... Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). Edasalonexent Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes). Ecraprost Ecraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease). Oleic monoethanolamide Not Available
- Drugs & Drug Targets