- Fatty Acids
- Accession Number
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
Drug Drug Description Indium In-111 satumomab pendetide For diagnosis of extrahepatic malignant cancers alpha-Linolenic acid A polyunsaturated omega-3 fatty acid found in many supplements. Dihomo-gamma-linolenic acid For nutritional supplementation, also for treating dietary shortage or imbalance Icosapent A polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements. Lipoic acid For nutritional supplementation, also for treating dietary shortage or imbalance. Gadodiamide A gadolinium-based contrast agent used for the visualization of lesions with vascularity during magnetic resonance imaging (MRI) scans. Calcium acetate A phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism. Travoprost A prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension. Valproic acid An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. Treprostinil A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol. Mupirocin An antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes. Carboprost tromethamine A prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective. Montelukast A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. Aminocaproic acid An antifibrinolytic agent used to induce clotting postoperatively. Foscarnet An antiviral used to treat CMV, HIV, and HSV infections. Candoxatril Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor. Clofibrate A fibric acid derivative used to treat hypertriglyceridemia and high cholesterol. Dextropropoxyphene An opioid analgesic used to treat mild to moderate pain. Latanoprost An isopropyl ester prodrug used to treat increased intraocular pressure. Mycophenolate mofetil An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants. Flurbiprofen An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Alprostadil A medication used to treat erectile dysfunction. Gadopentetic acid A gadolinium compound used as a contrast agent in MRIs. Progabide Indicated for the treatment of epilepsy. Benzylpenicilloyl polylysine A penicillin derivative used to determine penicillin allergies. Etacrynic acid A diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease. Bimatoprost A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. Dinoprostone A prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. Misoprostol A prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers. Zaleplon A sedative used for short term treatment of insomnia in adults. Edetic acid A chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias. Oxaprozin An NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. Mycophenolic acid An immunosuppressant used to prevent organ transplant rejections. Fenofibrate A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. Lubiprostone A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. Atorvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Vigabatrin An irreversible GABA transaminase inhibitor used as an adjunct therapy to treat refractory complex partial seizures in patients ≥2 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years. Iloprost A synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH). Fluvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Phenacemide Used to control certain seizures in the treatment of epilepsy. Rabeprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Dinoprost tromethamine Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities... Ridogrel Used as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction. Epoprostenol A vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure. Gemfibrozil A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. Aluminium monostearate Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging... Bezafibrate A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. gamma-Hydroxybutyric acid Used as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance. Tiaprofenic acid A nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis. Propyl acetate Not Available Aminooxyacetic acid A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem] 4-Oxosebacic Acid Not Available Prostaglandin B2 Not Available 12-Bromododecanoic Acid Not Available 4-(2-Thienyl)Butyric Acid Not Available Isobutyric acid Not Available Adenosine Phosphonoacetic Acid Not Available Fumagillin Not Available Acetamide Not Available Canaline Not Available Phosphonoacetic Acid A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem] 2-aminoisobutyric acid Not Available Ricinoleic acid Not Available Lauric acid Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily... Nitrilotriacetic acid Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.) Glycolic acid Not Available Acetic acid An antimicrobial agent used to treat susceptible infections of the external auditory canal. Stearic acid An ingredient found in topical products as a skin protectant. N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. Sparfosic acid Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen... Tricosanoic acid Not Available Butyric Acid A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester. Capric acid Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include... 12-Hydroxydodecanoic Acid Not Available 2-Methylbutanoic Acid Not Available Isovaleric Acid Not Available Dihydrolipoic Acid Not Available Palmitic Acid A fatty used as a food additive and emollient or surfactant in cosmetics. L-2,4-diaminobutyric acid Not Available Prostaglandin G2 A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] Coelenteramide Not Available 5-phenylpentanoic acid Not Available Valpromide A valproic acid derivative used to treat epilepsy and as adjunct therapy for psychomotor agitation, depression, and manic episodes of bipolar disorder. Mdl-29951 Not Available L-2-amino-3-butynoic acid Not Available Oleic Acid A naturally occurring fatty acid with antibacterial properties added to a variety of drug products. Palmitoleic Acid Not Available Alpha-Aminobutyric Acid Not Available Caprylic acid Caprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. It is found naturally in coconuts and breast milk. It is an oily liquid with a... Arachidonic Acid A natural fatty acid that plays an essential role in physiological homeostases, such as repair and growth of cells. 4,7-Dioxosebacic Acid Not Available 5-hydroxyvaleric acid Not Available Benoxaprofen The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets... Tienilic acid For the treatment of hypertension. Dexloxiglumide For the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD). Oleoyl-estrone For the treatment of obesity. Erdosteine A mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD). AN-9 Investigated for use/treatment in liver cancer, lung cancer, melanoma, and leukemia (lymphoid). Asimadoline Investigated for use/treatment in irritable bowel syndrome (IBS). Rilapladib Investigated for use/treatment in atherosclerosis and cardiovascular disorders. Gemcabene Investigated for use/treatment in atherosclerosis, cardiovascular disorders, and hyperlipidemia. Elafibranor Investigated for use/treatment in atherosclerosis and diabetes mellitus type 2. AM103 For the treatment of asthma and cardiovascular disease. Beraprost For the treatment of pulmonary hypertension. Fenoxaprop-ethyl Chronic angina and Coronary Artery Disease Caprospinol Alzheimer's Disease Tarenflurbil Investigated for use/treatment in alzheimer's disease and prostate cancer. Arundic acid Investigated for use/treatment in cerebral ischemia. C31G Investigated for use/treatment in contraception, HIV infection, and prevention of stdis. Emricasan Investigated for use/treatment in hepatitis (viral, C), liver disease, and transplantation (organ or tissue). Elacytarabine Investigated for use/treatment in leukemia (unspecified) and melanoma. Cobiprostone Investigated for use/treatment in cystic fibrosis. Bedoradrine Investigated for use/treatment in asthma and labor and delivery. BL-1020 Investigated for use/treatment in schizophrenia and schizoaffective disorders. Varespladib methyl Investigated for use/treatment in atherosclerosis and coronary artery disease. DP-b99 Investigated for use/treatment in strokes and traumatic brain injuries. DP-VPA Investigated for use/treatment in bipolar disorders, epilepsy, and migraine and cluster headaches. AGI-1096 Investigated for use/treatment in transplant (rejection). Tirbanibulin A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp. Indibulin Investigated for use/treatment in solid tumors. Lacosamide An antiepileptic drug used to treat partial onset seizures in adults. Senicapoc Investigated for use/treatment in anemia (sickle cell) and asthma. Fiboflapon Investigated for use/treatment in inflammatory disorders (unspecified). Avasimibe Investigated for use/treatment in peripheral vascular disease. Remacemide Investigated for use/treatment in epilepsy, huntington's disease, and parkinson's disease. Agomelatine Agomelatine is indicated to treat major depressive episodes in adults. Priralfinamide Investigated for use/treatment in pain (acute or chronic). Almorexant Investigated for use/treatment in sleep disorders and insomnia. Ethanolamine oleate A mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes. Zaltoprofen A non-steroidal anti-inflammatory drug approved for use in Japan in 1993. Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. Bendamustine An antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Levopropoxyphene Levopropoxyphene was used as an antitussive. An antitussive is a medication often recommended for the treatment of cough and associated respiratory tract disorders. Its enantiomer, dextropropoxyphene, presents an analgesic effect. Mangafodipir An organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas. Monoctanoin Monoctanoin is used to dissolve cholesterol gallstones. Nepafenac An ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. Unoprostone A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents. Sobetirome Not Available Sebacic acid Not Available 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid Metabolic product of biphenyl; from Pseudomonas putida. IDD594 Not Available Myristic acid Not Available Efaproxiral Not Available Dichloroacetic acid Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms.... Tafluprost An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Leukotriene C4 The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates... Gabapentin enacarbil A gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). Teriflunomide A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. Gadoxetic acid A gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to help characterize lesions in the liver. Icosapent ethyl An ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia. Arbaclofen Placarbil Investigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Gemeprost A prostaglandin E1 analogue used for cervical dilation and, in combination with mifepristone, for pregnancy termination. Etofibrate Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations. Clinofibrate Clinofibrate is a fibrate drug sold and marketed in Japan. Beclamide Has been used in the management of epilepsy and epilepsy related behavioural disorders. It was used for generalised tonic-clonic seizures, and was not effective for absence seizures. More recently focus... Ciprofibrate Not Annotated Sodium oxybate A central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. Uridine triacetate A pyrimidine analog used for the reversal of overdose, regardless of the presence of symptoms, and early-onset, severe or life-threatening CNS toxicity or cardiotoxicity of fluorouracil or capecitabine. Piracetam A nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer. Limaprost An oral prostaglandin E1 analogue used to improve symptoms associated with thromboangiitis obliterans, acquired lumbar spinal canal stenosis, and other ischemic conditions. Iproclozide For the treatment of depression. Pivhydrazine For the treatment of depression. Caroxazone For the treatment of depression. Sacubitril A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Sodium acetate A compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Omega-3-acid ethyl esters A mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia. Undecylenic acid An antifungal used to treat tinea species infections. Omega-3 fatty acids An ingredient found in a variety of supplements and vitamins. Trichloroacetate Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it... Calcium threonate No approved therapeutic indications. L-threonic acid Not Annotated Borage oil Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as... Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Selexipag A non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension. Fenprostalene Not Annotated Luprostiol Not Annotated Monensin Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds. Prostalene Analog of prostaglandin F2 alpha. Cloprostenol Not Annotated Fluprostenol Not Annotated Lesinurad A uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy. Latanoprostene bunod A prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma. PF-06282999 Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects). Antineoplaston A10 Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others. AZD-5672 Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis. VTP-194204 Nrx194204 has been used in trials studying the treatment of Parkinson's Disease and Non-small Cell Lung Cancer. Arhalofenate Arhalofenate has been investigated for the treatment of Gout and Hyperuricemia. Leukotriene D4 Leukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis. Etiracetam Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)). PF-00610355 PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others. Sutezolid Sutezolid has been used in trials studying the treatment of Tuberculosis. Varespladib Varespladib has been investigated for the treatment and prevention of Sickle Cell Disease, Vaso-occlusive Crisis, and Acute Coronary Syndrome. Ingavirin Ingavirin has been used in trials studying the treatment of Influenza and Common Cold. Atagabalin Atagabalin has been used in trials studying the treatment of Insomnia, Primary Insomnia, and Nonrestorative Sleep. Letermovir An antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). Orantinib Orantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others. Gefarnate Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. Ritobegron Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin... CPI-613 CPI-613 has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others. Figopitant Figopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers). Tricaprylin Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease. GSK-424887 Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and Anxiety Disorder. AZD-5423 AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD). 9CUAB30 9 Cuab30 has been used in trials studying the treatment and prevention of HER2/Neu Positive, HER2/Neu Negative, No Evidence of Disease, Estrogen Receptor Negative, and estrogen receptor positive, among others. Seladelpar Seladelpar (MBX-8025) has been used in trials studying the treatment of Hyperlipidemia. PD-217014 PD-217,014 has been used in trials studying the treatment of Pain and Irritable Bowel Syndrome. Clascoterone An androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older. Imiglitazar Imiglitazar has been used in trials studying the treatment of Diabetes Mellitus. MK-0686 MK0686 has been used in trials studying the treatment of Osteoarthritis, Pain, Postoperative, and Neuralgia, Postherpetic. Pentetreotide A somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours. Taprenepag Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle. 3,5-diiodothyropropionic acid DITPA has been investigated in Congestive Heart Failure. Sulprostone A prostaglandin analogue used to treat post-partum hemorrhaging, induce medical abortion, and induce labour in instances of in utero fetal death. Bindarit Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy. Lafutidine Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD). Dinoprost A medication used to induce a second trimester abortion. CMX-2043 CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. MK-0752 Mk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer). Pradigastat Pradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD). Pivagabine Pivagabine has been used in trials studying the treatment of Stress and Anxiety. Leukotriene B4 Leukotriene B4 has been used in trials studying the treatment of HIV Infections. MK-8245 MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus. Resolvin E1 Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers). Glycovir Glycovir has been used in trials studying the treatment of HIV Infections. Omega-6 fatty acids There are no current pharmacotherapeutic products based on omega-6 fatty acids. Fentiazac Not Annotated Etofamide Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued . Alminoprofen Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances. Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Difenpiramide Not Annotated Sodium feredetate Not Annotated Simfibrate Not Annotated Prethcamide Not Annotated Mazaticol Not Annotated Phenibut Not Annotated Cyclobutyrol Not Annotated Clefamide Not Annotated Pranoprofen A topical anti-inflammatory agent used for the treatment of non-infectious inflammatory conditions such as blepharitis and conjunctivitis. Pranoprofen ophthalmic solution may also be used post-operatively to manage inflammation. Lorcainide Not Annotated Epanolol Epanolol is an beta blocker. Meclofenoxate Not Annotated Enprostil Not Annotated Clofibride Not Annotated Gamolenic acid An ingredient found in a variety of nutritional products. Fenofibric acid A fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia. Isopropyl myristate A polar skin moisturizer that is used to enhance skin penetration of drugs. Pentetic acid DTPA is widely used in industry and medicine. As a medical agent, it is approved for its use in medical imaging and for the decorporation of internally deposited radionuclides. It... Palmidrol A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food... Hopantenic acid Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal... Gondoic acid Not Annotated Magnesium stearate Not Annotated Morrhuic acid Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil. Linoleic acid Not Annotated Sacubitrilat A metabolite of LCZ696 with neprilysin inhibitory activity. Threonic acid Not Annotated Zinc acetate A medication used to treat zinc deficiency. Potassium acetate A medication used to treat hypokalemia. Aluminum acetate A medication used for temporary relief of skin irritation. Peracetic acid A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant. Acetyl chloride Not Annotated cis-Vaccenic acid Not Available Prostaglandin D2 The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important... gamma-Aminobutyric acid The most common inhibitory neurotransmitter in the central nervous system. Oseltamivir acid Not Available Doconexent An omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. Propanoic acid An antimicrobial food additive. LY-518674 LY518674 has been used in trials studying the treatment of Metabolic Syndrome X. Methoxy arachidonyl fluorophosphonate Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid... Flurbiprofen axetil Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients). AZD-7687 AZD-7687 is under investigation in clinical trial NCT01119352 (AZD7687 Multiple Ascending Dose Study). Telaglenastat Telaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors). beta-Hydroxyisovaleric acid beta-Hydroxyisovaleric acid is under investigation in clinical trial NCT03018496 (Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.). Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). GLPG-0974 GLPG-0974 is under investigation in clinical trial NCT01721980 (Multiple Ascending Dose Study of GLPG0974 in Healthy Subjects). Thioglycolic acid Thioglycolic acid is under investigation in clinical trial NCT03238105 (Treatment of Periorbicular Hyperchromia Comparing 10% Thioglycolic Acid Peeling Versus Pulsed Intense Light). Norleucine Norleucine is under investigation in clinical trial NCT00081952 (Amino Acid Therapy for Hot Flashes in Postmenopausal Women). Remifentanil An opioid analgesic used in anesthesia. p-Coumaric acid Not Available Glesatinib Investigated for use/treatment in cancer/tumors (unspecified). Verinurad Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia. Radiprodil Radiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain. Ralinepag Ralinepag has been used in trials studying the treatment of Pulmonary Arterial Hypertension. Icosabutate Icosabutate is under investigation in clinical trial NCT02373176 ([14C] Icosabutate -A Phase I Absorption, Metabolism and Excretion Study). Osbond acid Not Annotated Triethylhexanoin Triethylhexanoin is an ingredient of cosmetic products as a fragrant solvent. Linrodostat Linrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants). Edasalonexent Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes). Pemafibrate Pemafibrate is under investigation in clinical trial NCT03350165 (A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)). Olorofim Olorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects). KH064 Not Available GW-590735 Not Available Andarine Andarine is a non-steroidal selective androgen receptor modulator. 1-Naphthoxyacetic acid Not Available R-95845 R-95845 is an inhibitor of HIV-1 reverse transcriptase. Hexadecanesulfonyl fluoride Not Available Indolepropionic acid Not Available 6-hydroxynorleucine Not Available N-hexadecanoylglycine Not Available Isocaproic acid Not Available Cetyl palmitate Not Annotated Thioctamide An ingredient in nutritional products for liver health. Gamma-amino-beta-hydroxybutyric acid An anticonvulsant indicated to treat convulsions in children and epilepsy. Gallium Ga-68 gozetotide A radiopharmaceutical agent used in the diagnosis of prostate-specific membrane antigen (PSMA) positive lesions in male patients during positron emission tomography. Adelmidrol Adelmidrol is under investigation in clinical trial NCT01420510 (Saginil in vs. Placebo for Gynecologic Oncology Patients Affected by Vaginitis). Ecraprost Ecraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease). Firsocostat Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)). Rivenprost Rivenprost is under investigation in clinical trial NCT00296556 (Therapeutic Study of ONO-4819CD for Ulcerative Colitis). Oleic monoethanolamide Not Available Glyceryl laurate Not Annotated Navtemadlin Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia).
- Drugs & Drug Targets