Thiophenes

Name
Thiophenes
Accession Number
DBCAT000374
Description

Not Available

Drugs
DrugDrug Description
Lipoic acidFor nutritional supplementation, also for treating dietary shortage or imbalance.
TiclopidineA platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
DuloxetineA serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
KetotifenA histamine H1 receptor blocker and mast cell stabilizer used to treat mild atopic asthma and allergic conjunctivitis.
Dihydrolipoic AcidNot Available
ThenoyltrifluoroacetoneThenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.
Tienilic acidFor the treatment of hypertension.
PizotifenA serotonin and tryptamine antagonist indicated for migraine prophylaxis.
PrasugrelA P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI.
RivaroxabanA factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
CanagliflozinA sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
ArticaineA local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures.
PyrantelAn anthelmintic used to treat helminth infections.
TiletamineThis drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt...
CMX-2043CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention.
TinoridineTinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).
OxantelAn antihelminthic indicated in the treatment of ascaris, trichocephaliasis, and oxyuriasis infections.
ThioctamideAn ingredient in nutritional products for liver health.
Drugs & Drug Targets
DrugTargetType
Lipoic acidLipoyltransferase 1, mitochondrialtarget
Lipoic acidSodium-dependent multivitamin transportertarget
Lipoic acidLipoyl synthase, mitochondrialtarget
Lipoic acidNADPH--cytochrome P450 reductaseenzyme
TiclopidineP2Y purinoceptor 12target
TiclopidineCytochrome P450 2C19enzyme
TiclopidineCytochrome P450 2B6enzyme
TiclopidineCytochrome P450 2C9enzyme
TiclopidineCytochrome P450 2D6enzyme
TiclopidineMyeloperoxidaseenzyme
TiclopidineCytochrome P450 1A2enzyme
TiclopidineCytochrome P450 2C8enzyme
TiclopidineCytochrome P450 2E1enzyme
DuloxetineSodium-dependent serotonin transportertarget
DuloxetineSodium-dependent dopamine transportertarget
DuloxetineSodium-dependent noradrenaline transportertarget
DuloxetineCytochrome P450 1A2enzyme
DuloxetineCytochrome P450 2D6enzyme
DuloxetineCytochrome P450 2C9enzyme
DuloxetineSerum albumincarrier
Duloxetinealpha1-acid glycoproteincarrier
DuloxetineP-glycoprotein 1transporter
DuloxetineCytochrome P450 3A4enzyme
DuloxetineCytochrome P450 2B6enzyme
DuloxetineCytochrome P450 2C19enzyme
ClopidogrelP2Y purinoceptor 12target
ClopidogrelCytochrome P450 3A4enzyme
ClopidogrelCytochrome P450 2B6enzyme
ClopidogrelCytochrome P450 3A5enzyme
ClopidogrelCytochrome P450 2C19enzyme
ClopidogrelCytochrome P450 2C9enzyme
ClopidogrelCytochrome P450 1A2enzyme
ClopidogrelCytochrome P450 2C8enzyme
ClopidogrelLiver carboxylesterase 1enzyme
ClopidogrelP-glycoprotein 1transporter
ClopidogrelSolute carrier family 22 member 1transporter
ClopidogrelSolute carrier family 22 member 2transporter
KetotifenHistamine H1 receptortarget
Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
KetotifenUDP-glucuronosyltransferase 1-3enzyme
KetotifenUDP-glucuronosyltransferase 1-4enzyme
KetotifenUDP-glucuronosyltransferase 2B10enzyme
Dihydrolipoic AcidAminomethyltransferasetarget
Dihydrolipoic AcidGlycine cleavage system H protein, mitochondrialtarget
Dihydrolipoic AcidDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialtarget
Dihydrolipoic Acid[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrialtarget
ThenoyltrifluoroacetoneLiver carboxylesterase 1target
ThenoyltrifluoroacetoneSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
Tienilic acidCytochrome P450 2C9enzyme
PizotifenMuscarinic acetylcholine receptor M2target
PizotifenMuscarinic acetylcholine receptor M1target
PizotifenMuscarinic acetylcholine receptor M3target
Pizotifen5-hydroxytryptamine receptor 2Atarget
Pizotifen5-hydroxytryptamine receptor 2Btarget
Pizotifen5-hydroxytryptamine receptor 2Ctarget
PizotifenHistamine H1 receptortarget
Pizotifen5-hydroxytryptamine receptor 1Atarget
Pizotifen5-hydroxytryptamine receptor 1Btarget
PizotifenAlpha-1A adrenergic receptortarget
PizotifenAlpha-1B adrenergic receptortarget
PizotifenAlpha-1D adrenergic receptortarget
PizotifenAlpha-2A adrenergic receptortarget
PizotifenAlpha-2B adrenergic receptortarget
PizotifenAlpha-2C adrenergic receptortarget
PizotifenUDP-glucuronosyltransferase 2B10enzyme
PrasugrelP2Y purinoceptor 12target
PrasugrelCocaine esteraseenzyme
PrasugrelCytochrome P450 3A4enzyme
PrasugrelCytochrome P450 2B6enzyme
PrasugrelCytochrome P450 2C9enzyme
PrasugrelCytochrome P450 2C19enzyme
PrasugrelSerum albumincarrier
RivaroxabanCoagulation factor Xtarget
RivaroxabanCytochrome P450 3A4enzyme
RivaroxabanCytochrome P450 2J2enzyme
RivaroxabanP-glycoprotein 1transporter
RivaroxabanCytochrome P450 3A5enzyme
RivaroxabanATP-binding cassette sub-family G member 2transporter
CanagliflozinUDP-glucuronosyltransferase 1-9enzyme
CanagliflozinUDP-glucuronosyltransferase 2B4enzyme
CanagliflozinCytochrome P450 3A4enzyme
CanagliflozinSodium/glucose cotransporter 2target
CanagliflozinP-glycoprotein 1transporter
CanagliflozinCanalicular multispecific organic anion transporter 1transporter
CanagliflozinAlpha-1-acid glycoprotein 1carrier
CanagliflozinATP-binding cassette sub-family G member 2transporter
PyrantelG-protein coupled receptor 35target
PyrantelCytochrome P450 4A11enzyme
PyrantelMuscarinic acetylcholine receptor M1target