- Accession Number
Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed)
- ATC Classification
Drug Drug Description Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Bupivacaine A local anesthetic used in a wide variety of superficial and invasive procedures. Prilocaine A local anesthetic used in dental procedures. Etidocaine Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage... Levobupivacaine For the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management Butanilicaine Not Annotated Oseltamivir A neuraminidase inhibitor used in the prophylaxis and treatment of influenza. Sildenafil A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. Dofetilide A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter. Cefotiam For treatment of severe infections caused by susceptible bacteria. Methyclothiazide A diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Cefmenoxime Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria. Cefmetazole For the treatment of infections caused by susceptible organisms. Flucloxacillin A narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA). Ertapenem A carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms. Ibutilide A class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion. Chlorthalidone A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions. Ethoxzolamide For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy. Acetaminophen An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. Piperacillin A penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam susceptible, β-lactamase generating strains of several bacteria. Aminohippuric acid A hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system. Aztreonam A beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Sulpiride A selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia. Remoxipride An discontinued atypical antipsychotic selective for dopamine D2 receptors. Ampicillin A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. Phenoxymethylpenicillin A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. Cefpiramide For treatment of severe infections caused by susceptible bacteria such as P. aeruginosa. Bendroflumethiazide A diuretic used to suppress lactation and to treat hypertension and edema. Ceftazidime An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others. Loracarbef Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,... Cefalotin A broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract. Celecoxib An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Dicloxacillin A penicillin used to treat penicillinase-producing bacterial infections that are susceptible to the drug. Cefotaxime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Flutamide An antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma. Metolazone A thiazide-like diuretic used to treat hypertension. Cinchocaine An anesthetic used for local or regional anesthesia. Bosentan A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. Benzthiazide For the treatment of high blood pressure and management of edema. Cephalexin A first generation cephalosporin used to treat certain susceptible bacterial infections. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Carbenicillin For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria. Valdecoxib A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Linezolid An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. Cisapride A medication used to treat heartburn associated with GERD. Cyclothiazide Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either... Nafcillin A penicillin derivative antibiotic used to treat susceptible staphylococcal infections. Rifabutin An antibiotic used to treat mycobacterium avium complex disease in patients with HIV. Imatinib A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. Sulfacetamide A corticosteroid used to treat inflammatory ocular conditions and acne vulgaris. Trimethobenzamide An antiemetic used to treat postoperative nausea and vomiting and nausea associated with gastroenteritis. Sulfametopyrazine For the treatment of urinary tract infection and chronic bronchitis. Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Cefixime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Cephaloglycin For treatment of severe infections caused by susceptible bacteria. Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. Amprenavir A protease inhibitor used to treat HIV infection. Tamsulosin An alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction. Oxacillin A penicillin antibiotic used to treat a number of susceptible bacterial infections. Hetacillin Hetacillin is a beta-lactam antibiotic prodrug used to treat bacterial infections. In the body it gets converted to ampicillin. Meropenem A carbapenem antibiotic used to treat a wide variety of infections in the body. Hydroflumethiazide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. Sulfasalazine An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. Indapamide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. Cefaclor A second generation cephalosporin used to treat a wide variety of infections in the body. Dorzolamide A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. Chlorothiazide A thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Bumetanide A sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Benzylpenicilloyl polylysine A penicillin derivative used to determine penicillin allergies. Bimatoprost A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. Ceforanide For the treatment of infections caused by susceptible organisms. Mezlocillin Used to treat serious gram–negative infections of the lungs, urinary tract, and skin. Zaleplon A sedative used for short term treatment of insomnia in adults. Hydrochlorothiazide A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. Cyclacillin For the treatment of bacterial infections caused by susceptible organisms. Trichlormethiazide Used in the treatment of oedema (including that associated with heart failure) and hypertension. Probenecid A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia. Cerulenin For use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals Procainamide A medication used to treat life threatening ventricular arrhythmias. Rifampicin An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. Benzylpenicillin A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. Tocainide An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. Amoxicillin A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Azlocillin For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae. Cefditoren A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract. Rosuvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Cefuroxime A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. Diazoxide A non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. Phenacemide Used to control certain seizures in the treatment of epilepsy. Bicalutamide An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate. Cefapirin For treatment of infections caused by susceptible bacteria. Cefadroxil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis. Diclofenamide A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. Cloxacillin An antibiotic agent used for the treatment of beta-hemolytic streptococcal and pneumococcal infections as well as staphylococcal infections. Cefprozil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections. Amdinocillin Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms. Procarbazine An antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents. Moclobemide A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. Brinzolamide A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Rifapentine An antibiotic agent used in the treatment of pulmonary tuberculosis. Levetiracetam A novel anticonvulsant agent used as an adjunct medication to manage partial onset, myoclonic, and generalized tonic-clonic seizures in patients with epilepsy. Ceftriaxone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract. Rifaximin A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. Encainide A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects. Metoclopramide An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Practolol Used in the emergency treatment of cardiac arrhythmias. Sulfacytine Used orally in the treatment of acute urinary tract infections. Sulfadoxine A long acting sulfonamide used for the treatment or prevention of malaria. Fosamprenavir An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. Polythiazide A thiazide diuretic used in the management of hypertension and treatment of edema. Quinethazone Used to treat hypertension. Cefamandole A beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections. Cefazolin A broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract. Cefonicid For the treatment of bacterial infections caused by susceptible microorganisms. Cefoperazone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts. Cefotetan An antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections. Cefoxitin A semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection. Ceftizoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea. Cefradine A first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues. Glymidine Glycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. Bezafibrate A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. Cefepime A fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections. Cefacetrile Cefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections. Ceftibuten A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis. Cefpodoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis. Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfamethazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Imipenem A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. Bacampicillin An ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections. Meticillin Used to treat infections caused by susceptible Gram-positive bacteria, particularly beta-lactamase-producing organisms such as Staphylococcus aureus that would otherwise be resistant to most penicillins. Pivampicillin An ampicillin prodrug used to treat a variety of infections. Pivmecillinam A prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs). Tazobactam A beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. Ticarcillin A beta lactam antibiotic used to treat a variety of infections in the body. SC-74020 Not Available Roflumilast A selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis. Piclamilast Piclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as... N,N-dimethylformamide Not Available WAY-151693 Not Available Geldanamycin Not Available N-Benzylformamide Not Available Acetamide Not Available Piretanide Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine... 3-Methoxybenzamide Not Available 4-Fluorobenzylamine Not Available Cephalosporin C Not Available Isopenicillin N Not Available Phenacetin Used principally as an analgesic. Salicylhydroxamic Acid Not Available Coelenteramide Not Available 1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea Not Available Paratoulene phosphate Not Available N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide Not Available Latamoxef Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,... Carboxin A systemic agricultural fungicide and seed treatment agent. Hydroxyfasudil Not Available Nimesulide For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Renzapride For the treatment of constipation-predominant irritable bowel syndrome (IBS-C). Ceftobiprole A cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria. Itopride Investigated for use/treatment in gastrointestinal diseases and disorders (miscellaneous). Rifalazil Investigated for use/treatment in atherosclerosis, bacterial infection, and peripheral vascular disease. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). Eprotirome Investigated for use/treatment in hyperlipidemia, metabolic disease, and obesity. ADL5859 Investigated for use/treatment in pain (acute or chronic). INCB13739 Investigated for use/treatment in diabetes mellitus type 2 and diabetes prevention. SLV319 Investigated for use/treatment in obesity. Cimicoxib Investigated for use/treatment in depression. Asimadoline Investigated for use/treatment in irritable bowel syndrome (IBS). AP5280 Investigated for use/treatment in solid tumors. Rilapladib Investigated for use/treatment in atherosclerosis and cardiovascular disorders. INCB3284 Investigated for use/treatment in inflammatory disorders (unspecified). Tanespimycin Investigated for use/treatment in leukemia (myeloid) and solid tumors. KD3010 Investigated for use/treatment in metabolic disease and obesity. APD791 For the treatment and prophylaxis of arterial thrombosis. XL765 For the treatment of various forms of cancer. Silver sulfadiazine A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. Actelion-1 Investigated for use/treatment in cardiovascular disorders, hypertension, and pulmonary hypertension. NCX 701 Investigated for use/treatment in pain (acute or chronic). AMG-131 Investigated for use/treatment in diabetes mellitus type 2. Naronapride Investigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis. Naluzotan Investigated for use/treatment in anxiety disorders and depression. Bedoradrine Investigated for use/treatment in asthma and labor and delivery. Retaspimycin Investigated for use/treatment in gastric cancer, lung cancer, and multiple myeloma. Faropenem medoxomil Investigated for use/treatment in bacterial infection, bronchitis, otitis media, and pediatric indications. SLx-4090 Investigated for use/treatment in hyperlipidemia. Elesclomol Investigated for use/treatment in melanoma. Cefilavancin Investigated for use/treatment in bacterial infection, skin infections/disorders, and staph bacterial infections. Trastuzumab emtansine An antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer. Laromustine Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), colorectal cancer, leukemia (lymphoid), leukemia (myeloid), lung cancer, myelodysplastic syndrome, pediatric indications, and solid tumors. UC-781 Investigated for use/treatment in HIV infection. Resatorvid Investigated for use/treatment in sepsis and septicemia. SNX-5422 Investigated for use/treatment in cancer/tumors (unspecified). Tirbanibulin A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Sulfadimethoxine For use in the treatment of infections. Indibulin Investigated for use/treatment in solid tumors. Ispinesib Investigated for use/treatment in breast cancer, lung cancer, solid tumors, renal cell carcinoma, pediatric indications, ovarian cancer, and head and neck cancer. Doripenem An antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. Lacosamide An antiepileptic drug used to treat partial onset seizures in adults. Udenafil Investigated for use/treatment in erectile dysfunction and hypertension. Senicapoc Investigated for use/treatment in anemia (sickle cell) and asthma. Amisulpride A dopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults. Simeprevir A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. Onalespib Investigated for use/treatment in cancer/tumors (unspecified). Refametinib Investigated for use/treatment in cancer/tumors (unspecified). AVE9633 Investigated for use/treatment in leukemia (myeloid). Tucidinostat Investigated for use/treatment in cancer/tumors (unspecified). Coltuximab ravtansine Investigated for use/treatment in lymphoma (non-hodgkin's). Elinogrel Investigated for use/treatment in cardiovascular disorders and myocardial infarction. Indisulam Investigated for use/treatment in lung cancer. Declopramide Investigated for use/treatment in colorectal cancer and inflammatory bowel disease. Remacemide Investigated for use/treatment in epilepsy, huntington's disease, and parkinson's disease. FK-960 Investigated for use/treatment in dementia, alzheimer's disease, schizophrenia and schizoaffective disorders, and memory loss. Tonabersat Investigated for use/treatment in migraine and cluster headaches. Pazopanib An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy. Ceftaroline fosamil An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. Agomelatine Agomelatine is indicated to treat major depressive episodes in adults. Saredutant Investigated for use/treatment in depression and anxiety disorders. Lixivaptan Investigated for use/treatment in hyponatremia and congestive heart failure. Almorexant Investigated for use/treatment in sleep disorders and insomnia. Clazosentan Investigated for use/treatment in strokes. Sulfaphenazole For the treatment bacterial infections. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Mafenide An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. Nepafenac An ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. Niclosamide For the treatment of tapeworm and intestinal fluke infections: Taenia saginata (Beef Tapeworm), Taenia solium (Pork Tapeworm), Diphyllobothrium latum (Fish Tapeworm), Fasciolopsis buski (large intestinal fluke). Niclosamide is also used... Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. m-Hydroxyhippuric acid Not Available TO-901317 TO-901317 is an LXRalpha and LXRbeta agonist. S-23 An androgen receptor modulator. 5-(2-methylpiperazine-1-sulfonyl)isoquinoline Not Available IDD594 Not Available Platensimycin Not Available 4-(2-AMINOETHYL)BENZENESULFONAMIDE Not Available Azidocillin For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including... Pipazethate For the treatment of cough. Salicylamide Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... Sulfamoxole For the treatment of bacterial infection. Cinitapride It is indicated to treat gastrointestinal disorders associated with motility disturbances like gastroesophageal reflux disease (GERD), non-ulcer dyspepsia and delayed gastric emptying. Vismodegib A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. Cabozantinib A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer. Vemurafenib A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. Mirabegron A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity. Macitentan An endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression. Indoramin Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Azosemide Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. Etamivan Etamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States. Cefaloridine Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH. Bromopride Bromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the... Ceftolozane A cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia. Blinatumomab An antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). Cefminox Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. Dasabuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Piracetam A nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer. Caroxazone For the treatment of depression. Propacetamol Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. Ombitasvir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Carindacillin A penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA. Procaine benzylpenicillin A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Sulbactam An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. Osimertinib A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma. Sulfabenzamide A sulfonamide antibacterial used as an ingredient in various topical and vaginal preparations to treat certain infections, but has been discontinued by the FDA. Triclocarban An antibacterial agent used in liquid soaps and body washes. Diethyltoluamide An insect repellant, also known as DEET. Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Selexipag A non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension. Cefroxadine Was used for the treatment of bacterial infections. Cefalonium Not Annotated Clorsulon Not Annotated Deracoxib Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to... Lufenuron Lufenuron is used in veterinary for the control of flea. Nicarbazin Not Annotated Sulfachlorpyridazine A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine. Sulfaethoxypyridazine Not Annotated Sulfanitran Not Annotated Sulfaquinoxaline Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K... Zoalene Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry. Ceftiofur Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active... Cefovecin Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. It is the first single-dose injectable antibiotic for dogs and cats that assures owner... Imidocarb Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites. Venetoclax A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. Asunaprevir An NS3 protease inhibitor used to treat hepatitis C genotype 1b. Nitrocefin Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin... Pictilisib Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others. AZD-4877 AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others. Mosapride A prokinetic 5-HT4 receptor agonist used to stimulate gastric motility. PF-06282999 Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects). Pavinetant Pavinetant has been used in trials studying the basic science and treatment of Safety and Schizophrenia. Antineoplaston A10 Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others. Acalabrutinib A Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. Navarixin Navarixin has been investigated for the treatment of Asthma. Encorafenib A kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations. Lasmiditan An oral 5HT1F agonist used for the acute treatment of migraine headache with or without aura. Vonoprazan A potassium-competitive acid blocker used in the treatment of erosive diseases of the digestive tract, including reflux esophagitis and duodenal ulcers. Momelotinib Momelotinib has been used in trials studying the treatment of Polycythemia Vera, Primary Myelofibrosis, Post-Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis (PMF), among others. Spebrutinib Spebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell. Pilaralisib Pilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors,... Danusertib Danusertib has been used in trials studying the treatment of Leukemia. Danoprevir Danoprevir has been used in trials studying the treatment of Hepatitis C, Chronic. Mirodenafil Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction. AZD-5672 Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis. Arhalofenate Arhalofenate has been investigated for the treatment of Gout and Hyperuricemia. Baricitinib A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. Danegaptide Danegaptide has been investigated for the treatment of Focus of Study is STEMI. TMC-647055 TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, and Chronic Hepatitis C Virus. Mocetinostat Mocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others. Entinostat Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic... PF-04958242 PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural. Revefenacin An anticholinergic agent used to treat COPD. Litronesib Litronesib has been used in trials studying the treatment of Solid Tumors, Ovarian Cancer, Gastric Cancer, Prostate Cancer, and Acute Leukaemia, among others. Etiracetam Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)). PF-00610355 PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others. Avagacestat Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease. Gisadenafil Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia. Flumatinib Flumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic. Sutezolid Sutezolid has been used in trials studying the treatment of Tuberculosis. Rociletinib Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer. Flomoxef Flomoxef has been used in trials studying the treatment of Urinary Tract Infection. Tasisulam Tasisulam has been used in trials studying the treatment and basic science of Melanoma, Lymphoma, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others. Entrectinib Entrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment... Axelopran Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation. Setrobuvir Setrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic. T-900607 T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer. Lorvotuzumab mertansine Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others. CE-224535 CE-224535 has been used in trials studying the treatment of Osteoarthritis. Figopitant Figopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers). Sultamicillin Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD). Lorlatinib An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. Elubrixin Elubrixin has been used in trials studying the treatment of Cystic Fibrosis, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease (COPD). Presatovir Presatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections. Faropenem Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia. N-6022 N6022 has been used in trials studying the treatment of Asthma and Cystic Fibrosis. Verdinexor Kpt 335 is under investigation in clinical trial NCT02431364 (Trial of Safety and Tolerability of Oral Verdinexor (Verdinexor) in Healthy Adults). GSK-424887 Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and Anxiety Disorder. KRN-7000 KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients... Iguratimod Iguratimod is under investigation in Rheumatoid Arthritis. Balicatib Balicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis. ABT-751 ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer. Begacestat Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease. Vidupiprant Vidupiprant has been used in trials studying the treatment and basic science of Asthma. AZD-5423 AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD). Darexaban Darexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others. Bavisant Bavisant has been used in trials studying the basic science and treatment of Alcoholism, Pharmacokinetics, Drug Interactions, Attention Deficit Hyperactivity Disorder, and Attention Deficit Disorders With Hyperactivity. Radotinib Radotinib is indicated for the treatment of different types of cancer, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other Bcr-Abl tyrosine-kinase inhibitors, such... Navitoclax Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is... LY-2456302 Ly2456302 has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence. Temocillin Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. Betrixaban A Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients. Apricoxib Apricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others. Resminostat Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others. Polmacoxib Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee. Voxtalisib Voxtalisib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Breast Cancer, among others. PAC-14028 PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea. CI-1040 CI-1040 has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Breast Neoplasms, Pancreatic Cancer, and Colorectal Cancer, among others. Ioforminol Ioforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH With or Without PCI. Alvespimycin Investigated for use as an antineoplastic agent for solid tumors, advanced solid tumours or acute myeloid leukaemia. Acotiamide Acotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia. Mirvetuximab Soravtansine Mirvetuximab Soravtansine has been used in trials studying the treatment of Ovarian cancer, Endometrial Cancer, Fallopian tube cancer, Epithelial Ovarian Cancer, and Primary Peritoneal Cancer, among others. Fedratinib Fedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk. E-7820 E7820 has been investigated for the treatment of Colon Cancer and Rectal Cancer. Raclopride Raclopride has been used in trials studying Parkinson Disease. BI-671800 Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial. MK-0686 MK0686 has been used in trials studying the treatment of Osteoarthritis, Pain, Postoperative, and Neuralgia, Postherpetic. Piperine Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders. Razupenem Razupenem has been used in trials studying the treatment of Skin Infections. AZD-9056 AZD9056 has been used in trials studying the basic science and treatment of Rheumatoid Arthritis. Reparixin Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type 1, and Pancreatic... Taprenepag Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle. JNJ-41443532 JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2. Ibipinabant Ibipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes. Omipalisib Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis. Pilsicainide Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation. Mibampator Mibampator has been used in trials studying the treatment of Alzheimer's Disease. Daporinad Daporinad has been used in trials studying the treatment of Melanoma, Cutaneous T-cell Lymphoma, and B-cell Chronic Lymphocytic Leukemia. Lafutidine Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD). Relenopride Relenopride has been used in trials studying the treatment of Chronic Idiopathic Constipation. CHF-6001 CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease. Ataciguat Ataciguat has been investigated for the basic science of Aortic Valve Stenosis. Grapiprant The effects of grapiprant have been investigated in the area of analgesia and anti-inflammation due to the effects that have been reported about this molecule. This molecule has been approved... DA-6886 DA-6886 has been used in trials studying the treatment of Irritable Bowel Syndrome. Sivelestat Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult. Tazemetostat A methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. Chlorsulfaquinoxaline Chlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer. RO-4987655 RO4987655 has been used in trials studying the treatment of Neoplasms. Granotapide Granotapide has been used in trials studying the treatment of Type II Diabetes Mellitus. IPI-493 IPI-493 has been used in trials studying the treatment of Advanced Malignancies. Tiapride Tiapride is indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly. Biapenem Biapenem has been used in trials studying the treatment of Bacterial Infections. Ramatroban Ramatroban has been used in trials studying the treatment of Asthma. CH-5132799 CH5132799 has been used in trials studying the treatment of Solid Tumors. Upamostat Upamostat has been used in trials studying the treatment of Pancreatic Cancer. SCYX-7158 SCYX-7158 has been used in trials studying the treatment of Trypanosomiasis, Parasitic Diseases, Protozoan Infections, and Trypanosomiasis, African. Inosine pranobex A medication used to treat subacute sclerosing panencephalitis. Ripasudil Ripasudil has been proven to be effective in the twice daily treatment of glaucoma and ocular hypertension. It is currently in studies to be approved for both diabetic retinopathy and... Phthalylsulfathiazole Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon . Etofamide Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued . Penimepicycline Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification... Cefatrizine Not Annotated Sultopride Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics . Sulfaisodimidine Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has... Epicillin Not Annotated Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Difenpiramide Not Annotated Mefruside Not Annotated Iobenzamic acid Not Annotated Mebutizide Not Annotated Cefodizime A broad-spectrum, third-generation cephalosporin used to treat serious infections caused by susceptible bacteria. Cefsulodin Not Annotated Cefetamet Not Annotated Carfecillin Not Annotated Clebopride Not Annotated Clefamide Not Annotated Veralipride Not Annotated Cyclopenthiazide Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients... Ethenzamide Not Annotated Sulfatolamide Not Annotated Carumonam Not Annotated Succinylsulfathiazole Not Annotated Clorexolone Not Annotated Cefbuperazone Not Annotated Lorcainide Not Annotated Benorilate Not Annotated Propicillin Not Annotated Cefozopran Not Annotated Cefpirome Not Annotated Sulbenicillin Not Annotated Sulfathiourea Not Annotated Sulfaguanidine Not Annotated Penamecillin Not Annotated Epanolol Epanolol is an beta blocker. Sulfamethoxypyridazine Not Annotated Cefazedone Not Annotated Clopamide Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure. Xipamide Not Annotated Talampicillin Not Annotated Aspoxicillin Not Annotated Ceftezole Not Annotated Metampicillin Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the... Iniparib Not Annotated SB-269970 SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist... Acetyl sulfisoxazole Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the... SC-236 SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , . NS-398 NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases. 7-Aminodesacetoxycephalosporanic acid Not Annotated Ticalopride Investigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis. Estradiol sulfamate Investigated for use/treatment in endometriosis. Ceramide AP Not Annotated Ceramide NG Not Annotated Brovanexine Not Annotated Oseltamivir acid Not Available CGP 4832 Not Available PD-0325901 PD-0325901 has been used in trials studying the treatment and basic science of Melanoma, Solid Tumour, Solid Tumors, Advanced Cancer, and Breast Neoplasms, among others. Nesbuvir Nesbuvir has been investigated for the treatment of Hepatitis C. PH-797804 PH-797804 has been investigated for the treatment of Osteoarthritis. Fasudil Fasudil has been investigated in Carotid Stenosis. Rifamycin An antibacterial used to treat traveler's diarrhea. Tecovirimat An antiviral medication used to treat smallpox. Foretinib Foretinib has been used in trials studying the treatment of Cancer, Breast Cancer, Carcinoma, Renal Cell, Recurrent Breast Cancer, and Neoplasms, Head and Neck, among others. Foretinib is an orally... Ropivacaine An analgesic drug used for local or regional anesthesia for surgery and short-term management of pain. Mepivacaine A local anesthetic used for local or regional analgesia or anesthesia. Articaine A local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures. Cefamandole nafate Not Annotated Mebenil An obsolete fungicide used to control various pathogens on cereals and seed potatoes. Ceftobiprole medocaril Ceftobiprole medocaril is a ceftobiprole prodrug. Diethyltryptamine Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine. Anetumab ravtansine Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer). TAS-116 TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors). GTX-758 GTX-758 is under investigation in clinical trial NCT01420861 (GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer). ABT-639 ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain). Aprocitentan Aprocitentan is under investigation in clinical trial NCT03541174 (A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and... Fallypride Fallypride is under investigation in clinical trial NCT02310360 (Striatal and Extra-striatal Dopamine Release in Response to Food in Healthy Humans). Dubermatinib Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL). Birabresib Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)). JNJ-26489112 JNJ-26489112 is under investigation in clinical trial NCT00579384 (A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy). 25-desacetylrifapentine 25-desacetylrifapentine is under investigation in clinical trial NCT00023387 (TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine). Telaglenastat Telaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors). Vercirnon Vercirnon is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. It is... Sulopenem Sulopenem is under investigation in clinical trial NCT03357614 (Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults). Florasulam Florasulam is under investigation in clinical trial NCT01193465 (Temperature and Humidity Among Different Anesthesia Work-station). VM4-037 VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037). Tefinostat Tefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)). Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). Giripladib Giripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee). Iodohippuric acid Iodohippuric acid is under investigation in clinical trial NCT02599844 (Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults). Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Vorinostat A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. Glesatinib Investigated for use/treatment in cancer/tumors (unspecified). Axitinib An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy. Afatinib An antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy. Epacadostat Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others. PF-00489791 PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic Nephropathies, Hypertension, Pulmonary, and Peripheral Vascular Disease. Voxilaprevir A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. Enobosarm Enobosarm has been used in trials studying the treatment of Stress Urinary Incontinence and Triple Negative Breast Cancer. Radiprodil Radiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain. Defactinib Defactinib has been investigated for the treatment of Malignant Pleural Mesothelioma. GLPG-0187 GLPG0187 has been used in trials studying the treatment of Solid Tumors. ACT-451840 ACT-451840 has been used in trials studying Malaria. CEP-37440 CEP-37440 has been used in trials studying the treatment of Solid Tumors. 4SC-202 4SC-202 has been used in trials studying the treatment of Advanced Hematologic Malignancies. Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. LGD-6972 LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus). Lanifibranor Lanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337). PF-05089771 PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee). Cefiderocol A cephalosporin antibiotic used in complicated urinary tract infections. Linrodostat Linrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants). Pyrotinib Pyrotinib is under investigation in clinical trial NCT03756064 (Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer). Edasalonexent Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes). TAK-243 TAK-243 is under investigation in clinical trial NCT03816319 (TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia). Sitravatinib Sitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma). ABT-072 ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat... Olorofim Olorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects). Eticlopride Not Annotated 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Not Available Deacetoxycephalosporin C Not Available ICI-164384 Not Available PLX-4720 Not Available GW-813893 Not Available Andarine Andarine is a non-steroidal selective androgen receptor modulator. CGS-27023 Not Available H-89 Not Available R-95845 R-95845 is an inhibitor of HIV-1 reverse transcriptase. Cyclohexylformamide Not Available Fasitibant Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee). Capmatinib A kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping. Sulbactam pivoxil Not Annotated Buthiazide Not Annotated Sulfametrole An antibiotic indicated in combination intravenous products for various bacterial infections. Salicylamide O-acetic acid A salicylate indicated in combination with local anesthetics and corticosteroids for short term treatment of inflammation. Levosulpiride indicated to treat dyspepsia, symptoms of Meniere's syndrome, and second line in the treatment of drug-induced nausea and vomiting. PLX8394 PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors). APG-1387 APG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B). Batabulin Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients). TAK-715 TAK-715 is under investigation in clinical trial NCT00760864 (Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis). Indatuximab ravtansine Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma). Ladarixin Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function). Methfuroxam Methfuroxam is under investigation in clinical trial NCT01213407 (Dendritic Cell Cancer Vaccine for High-grade Glioma). Mitapivat Mitapivat is under investigation in clinical trial NCT03548220 (A Study to Evaluate Efficacy and Safety of AG-348 in Not Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)). TNP-2092 TNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection). ABX-196 ABX-196 is under investigation in clinical trial NCT03897543 (ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma).
- Drugs & Drug Targets