Amides
- Name
- Amides
- Accession Number
- DBCAT000494
- Description
Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed)
- Drugs
Drug Drug Description 1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea Not Available 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID Not Available 2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamide Not Available 2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide Not Available 2-chloroethyl-3-sarcosinamide-1-nitrosourea 2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific. 3-Methoxybenzamide Not Available 4-(2-AMINOETHYL)BENZENESULFONAMIDE Not Available 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Not Available 4-Fluorobenzylamine Not Available 7-Aminodesacetoxycephalosporanic acid Not Annotated Abivertinib Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in... Abrocitinib A kinase inhibitor used to treat moderate-to-severe atopic dermatitis in adults. ABSK-091 Not Annotated ABT-072 ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat... ABT-102 Not Annotated ABT-639 ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain). ABT-737 An inhibitor of members of the Bcl‑2 family of apoptosis regulators. ABT-751 ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer. ABX-196 ABX-196 is under investigation in clinical trial NCT03897543 (ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma). Acalabrutinib A Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. Acecarbromal Acecarbromal is a small molecule drug. Acecarbromal has a monoisotopic molecular weight of 278.03 Da. Acetamide Not Available Acetaminophen An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. Acetohexamide Used in the management of diabetes mellitus type 2 (adult-onset). Acetyl sulfisoxazole Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the... Acetyldinaline Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma). Acoltremon Acoltremon is under investigation in clinical trial NCT05493111 (A Long-term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512). Acotiamide Acotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia. Acoziborole SCYX-7158 has been used in trials studying the treatment of Trypanosomiasis, Parasitic Diseases, Protozoan Infections, and Trypanosomiasis, African. ACT-451840 ACT-451840 has been used in trials studying Malaria. Actelion-1 Investigated for use/treatment in cardiovascular disorders, hypertension, and pulmonary hypertension. Acumapimod Acumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers). ADL-5859 ADL-5859 is under investigation in clinical trial NCT00626275 (Study Evaluating the Analgesic Efficacy and Safety of ADL5859 in Participants With Rheumatoid Arthritis). Afatinib An antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy. Agerafenib Agerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations). Agomelatine Agomelatine is indicated to treat major depressive episodes in adults. Allantoin An ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. Allitinib Allitinib is under investigation in clinical trial NCT04671303 (To Evaluate the Efficacy and Safety of Anlotinib Combined With Allitinib in Lung Cancer). Alloclamide Alloclamide is a small molecule drug. Alloclamide has a monoisotopic molecular weight of 310.14 Da. Allylthiourea Allylthiourea is a small molecule drug. Allylthiourea has a monoisotopic molecular weight of 116.04 Da. Almonertinib A third-generation, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) indicated for the treatment of patients with metastatic EGFR T790M mutation-positive non-small cell lung cancer (NSCLC). Almorexant Investigated for use/treatment in sleep disorders and insomnia. Alofanib Alofanib is a small molecule drug. The usage of the INN stem '-anib' in the name indicates that Alofanib is a angiogenesis inhibitor. Alofanib is under investigation in clinical trial... Alpha-galactosylceramide KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients... Altiratinib Not Annotated Alvespimycin Investigated for use as an antineoplastic agent for solid tumors, advanced solid tumours or acute myeloid leukaemia. AM-211 Not Annotated AM-461 Not Annotated Amdinocillin Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms. Ameltolide Ameltolide is a small molecule drug. Ameltolide has a monoisotopic molecular weight of 240.13 Da. Aminohippuric acid A hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system. Aminoquinuride Not Available Amisulpride A dopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults. Amoxicillin A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Ampicillin A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. Amprenavir A protease inhibitor used to treat HIV infection. Amuvatinib Amuvatinib is a selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3. Amuvatinib also suppresses Rad51 protein, a critical component of... ANC-501 ANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder). Andarine Andarine is a non-steroidal selective androgen receptor modulator. Andolast Andolast is a small molecule drug. Andolast has a monoisotopic molecular weight of 333.11 Da. Antineoplaston A10 Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others. AP5280 Investigated for use/treatment in solid tumors. Apalcillin Apalcillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Apalcillin is a antibiotic, 6-aminopenicillanic acid derivative. Apalcillin has a monoisotopic molecular... Apararenone Apararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995). APG-1387 APG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B). Apinocaltamide Apinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients). Apricoxib Apricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others. Aprocitentan An endothelin receptor antagonist used for the treatment of uncontrolled hypertension in patients inadequately controlled on other treatments. Apronalide Apronalide is approved in Japan. Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura . AR-12 Not Annotated AR-9281 Investigated for use/treatment in hypertension. AR-AO-14418 Not Available Argatroban A synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use. Arhalofenate Arhalofenate has been investigated for the treatment of Gout and Hyperuricemia. Articaine A local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures. Asapiprant Asapiprant is a small molecule drug. Asapiprant is under investigation in clinical trial NCT04705597 (Study to Evaluate the Safety, Tolerability, and Efficacy of BGE-175 in Hospitalized Adults With Coronavirus Disease... Asimadoline Investigated for use/treatment in irritable bowel syndrome (IBS). Asivatrep PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea. Asnuciclib Asnuciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Asnuciclib is a cyclin dependant kinase inhibitor. Asnuciclib has a monoisotopic molecular... Aspoxicillin Not Annotated AST-487 Not Annotated Asunaprevir An NS3 protease inhibitor used to treat hepatitis C genotype 1b. Asundexian Asundexian is under investigation in clinical trial NCT05686070 (A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After... AT9283 Investigated for use/treatment in cancer/tumors (unspecified), leukemia (myeloid), and solid tumors. Ataciguat Ataciguat has been investigated for the basic science of Aortic Valve Stenosis. Aticaprant Aticaprant has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence. Atreleuton Atreleuton has been used in trials studying the treatment of Atherosclerosis and Coronary Artery Disease. Atuveciclib Atuveciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Atuveciclib is a cyclin dependant kinase inhibitor. Atuveciclib is under investigation in... Avagacestat Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease. Avasimibe Investigated for use/treatment in peripheral vascular disease. Avitriptan Avitriptan is a small molecule drug. The usage of the INN stem '-triptan' in the name indicates that Avitriptan is a sumatriptan derivative serotonin (5HT1) receptor agonist. Avitriptan has a... AVN-944 Investigated for use/treatment in cancer/tumors (unspecified), leukemia (unspecified), lymphoma (unspecified), multiple myeloma, and pancreatic cancer. Avoralstat Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema. Axelopran Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation. Axitinib An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy. AZD-1236 AZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic Obstructive Pulmonary Disease. AZD-4877 AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others. AZD-5069 Not Annotated AZD-5423 AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD). AZD-5672 Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis. AZD-6703 Not Annotated Azd-7624 Not Annotated AZD-7762 AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies. AZD-9056 AZD9056 has been used in trials studying the basic science and treatment of Rheumatoid Arthritis. Azidocillin For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including... Azlocillin For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae. Azosemide Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. Aztreonam A beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. Bacampicillin An ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections. Balicatib Balicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis. Baricitinib A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. Batabulin Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients). Bavisant Bavisant has been used in trials studying the basic science and treatment of Alcoholism, Pharmacokinetics, Drug Interactions, Attention Deficit Hyperactivity Disorder, and Attention Deficit Disorders With Hyperactivity. Bedoradrine Investigated for use/treatment in asthma and labor and delivery. Befotertinib Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive Patients With Advanced Egfr-mutant Lung Cancer). Begacestat Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). Belumosudil An oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD). Benapenem Benapenem is under investigation in clinical trial NCT04505683 (A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (Cuti) or Acute Pyelonephritis (AP)). Benorilate Not Annotated Benzolamide Not Available Benzotript Benzotript is a small molecule drug. Benzotript has a monoisotopic molecular weight of 342.08 Da. Benzylpenicillin A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. Benzylpenicilloyl polylysine A penicillin derivative used to determine penicillin allergies. Betrixaban A Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients. Bezafibrate A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. BI-671800 Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial. Biapenem A carbapenem antibiotic indicated in the treatment of bacterial infections. Bicalutamide An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate. Bimatoprost A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. Birabresib Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)). Bizelesin Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. BLU-9931 Not Annotated BMS-817399 BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis). BMS-833923 Not Annotated BMS-986141 BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants). Bomedemstat Not Annotated Bosentan A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. Brinzolamide A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Brobactam Brobactam is a small molecule drug. The usage of the INN stem '-bactam' in the name indicates that Brobactam is a ẞ-lactamase inhibitor. Brobactam has a monoisotopic molecular weight of... Bromisoval Not Annotated Bromopride A substituted benzamide, closely related to metoclopramide, used as an antiemetic. Brotianide Brotianide is a small molecule drug. Brotianide has a monoisotopic molecular weight of 460.85 Da. Brovanexine Not Annotated Buclosamide Buclosamide is a small molecule drug. Buclosamide has a monoisotopic molecular weight of 227.07 Da. Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Buloxibutid Not Annotated Bumetanide A sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome. Bupivacaine A local anesthetic used in a wide variety of superficial and invasive procedures. Butanilicaine Not Annotated Cabozantinib A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer. Capmatinib A kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Caracemide Caracemide is a small molecule drug. Caracemide has a monoisotopic molecular weight of 189.07 Da. Carbamide peroxide A medication used to loosen ear wax, whiten teeth, and clean oral wounds. Carbapenem Not Annotated Carbaspirin calcium An NSAID indicated in the treatment of short term pain and fever. Carbenicillin For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria. Carboxin A systemic agricultural fungicide and seed treatment agent. Carbromal Not Annotated Carbutamide Not Annotated Carfecillin Not Annotated Carindacillin A penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA. Carmustine An alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others. Caroxazone For the treatment of depression. Carumonam Not Annotated Casopitant Investigated for use/treatment in urinary incontinence and adverse effects (chemotherapy). CE-224535 CE-224535 has been used in trials studying the treatment of Osteoarthritis. Cefacetrile A broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections. Cefaclor A second generation cephalosporin used to treat a wide variety of infections in the body. Cefadroxil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis. Cefalonium Not Annotated Cefaloridine Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH. Cefalotin A broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract. Cefamandole A beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections. Cefamandole nafate A second generation cephalosporin indicated in the prevention of infections during surgery. Cefapirin A first generation cephalosporin indicated in the treatment of susceptible bacterial infections. Cefatrizine Not Annotated Cefazedone Not Annotated Cefazolin A broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract. Cefbuperazone Not Annotated Cefcanel Cefcanel is a small molecule drug. Cefcanel has a monoisotopic molecular weight of 478.04 Da. Cefcanel daloxate Cefcanel daloxate is a small molecule drug. Cefcanel daloxate has a monoisotopic molecular weight of 661.1 Da. Cefclidin Cefclidin is a small molecule drug. Cefclidin has a monoisotopic molecular weight of 550.14 Da. Cefditoren A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract. Cefepime A fourth-generation cephalosporin antibiotic used in the treatment of infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections. Cefetamet Not Annotated Cefetamet pivoxil Cefetamet pivoxil is under investigation in clinical trial NCT04664803 (Safety and Efficacy of Cefecin Tab. in Patients With Acute Sinusitis). Cefiderocol A cephalosporin antibiotic used in complicated urinary tract infections. Cefilavancin Investigated for use/treatment in bacterial infection, skin infections/disorders, and staph bacterial infections. Cefixime A third generation cephalosporin used to treat susceptible Gram-negative and Gram-positive bacterial infections. Cefmatilen Cefmatilen is a small molecule drug. Cefmatilen has a monoisotopic molecular weight of 514.0 Da. Cefmenoxime Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria. Cefmetazole A cephalosporin antibiotic used to treat a variety of bacterial infections. Cefminox Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan. Cefodizime A broad-spectrum, third-generation cephalosporin used to treat serious infections caused by susceptible bacteria. Cefonicid For the treatment of bacterial infections caused by susceptible microorganisms. Cefoperazone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts. Ceforanide For the treatment of infections caused by susceptible organisms. Cefoselis Cefoselis is a small molecule drug. Cefoselis has a monoisotopic molecular weight of 522.11 Da. Cefotaxime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Cefotetan An antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections. Cefotiam A cephalosporin antibiotic used to treat a variety of bacterial infections. Cefovecin Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. It is the first single-dose injectable antibiotic for dogs and cats that assures owner... Cefoxitin A semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection. Cefozopran Not Annotated Cefpimizole Cefpimizole is a small molecule drug. Cefpimizole has a monoisotopic molecular weight of 670.12 Da. Cefpiramide For treatment of severe infections caused by susceptible bacteria such as P. aeruginosa. Cefpirome An antibiotic indicated in the treatment of a wide variety of infections in the body. Cefpodoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis. Cefprozil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections. Cefradine A first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues. Cefroxadine Was used for the treatment of bacterial infections. Cefsulodin Not Annotated Cefsumide Cefsumide is a small molecule drug. Cefsumide has a monoisotopic molecular weight of 440.08 Da. Ceftaroline fosamil An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. Ceftazidime An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others. Ceftezole Not Annotated Ceftibuten A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis. Ceftiofur Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active... Ceftizoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea. Ceftobiprole A broad spectrum 5th-generation cephalosporin antibacterial indicated for certain kinds of pneumonia, bacteremia, and skin and skin structure infections, including those caused by MRSA. Ceftobiprole medocaril A broad spectrum 5th-generation cephalosporin antibacterial indicated for certain kinds of pneumonia, bacteremia, and skin and skin structure infections, including those caused by MRSA. Ceftolozane A cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia. Ceftriaxone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract. Cefuroxime A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. Cefuzonam Cefuzonam is a small molecule drug. Cefuzonam has a monoisotopic molecular weight of 513.0 Da. Celecoxib An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Celiprolol A beta-blocker for the management of hypertension and angina pectoris. CEP-37440 CEP-37440 has been used in trials studying the treatment of Solid Tumors. Cephalexin A first generation cephalosporin used to treat certain susceptible bacterial infections. Cephaloglycin For treatment of severe infections caused by susceptible bacteria. Cephalosporin C Not Available Ceralasertib Ceralasertib is under investigation in clinical trial NCT03682289 (Phase II Trial of AZD6738 Alone and in Combination With Olaparib). Ceramide AP Not Annotated Ceramide NG Not Annotated Cerulenin For use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals CGI-1842 JI-101 has been used in trials studying the treatment of Cancer, Colon Cancer, Neuroendocrine, Ovarian Cancer, and Advanced Solid Tumors. CGS-27023 Not Available CH-5132799 CH5132799 has been used in trials studying the treatment of Solid Tumors. Chlorpropamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Chlorsulfaquinoxaline Chlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer. Chlorthalidone A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions. CI-1040 CI-1040 has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Breast Neoplasms, Pancreatic Cancer, and Colorectal Cancer, among others. Cimicoxib Investigated for use/treatment in depression. Cinchocaine An anesthetic used for local or regional anesthesia. Cinitapride A benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying. Cisapride A medication used to treat heartburn associated with GERD. Clamidoxic acid Clamidoxic acid is a small molecule drug. Clamidoxic acid has a monoisotopic molecular weight of 339.01 Da. Clamikalant Clamikalant is a small molecule drug. The usage of the INN stem '-kalant' in the name indicates that Clamikalant is a potassium channel blocker. Clamikalant has a monoisotopic molecular weight... Clanfenur Clanfenur is a small molecule drug. Clanfenur has a monoisotopic molecular weight of 335.08 Da. Clazosentan Investigated for use/treatment in strokes. Clebopride A dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy. Clefamide Not Annotated Clioxanide Clioxanide is a small molecule drug. Clioxanide has a monoisotopic molecular weight of 540.84 Da. Cloflucarban Cloflucarban is a small molecule drug. Cloflucarban has a monoisotopic molecular weight of 348.0 Da. Clofutriben Clofutriben is a small molecule drug. Clofutriben is under investigation in clinical trial NCT05307328 (SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome). Clofutriben has a monoisotopic molecular weight of... Cloguanamil Cloguanamil is a small molecule drug. Cloguanamil has a monoisotopic molecular weight of 237.04 Da. Clopamide Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure. Clorexolone Not Annotated Clorsulon Not Annotated Cloxacepride Cloxacepride is a small molecule drug. The usage of the INN stem '-pride' in the name indicates that Cloxacepride is a sulpiride derivative and analogue. Cloxacepride has a monoisotopic molecular... Cloxacillin An antibiotic agent used for the treatment of beta-hemolytic streptococcal and pneumococcal infections as well as staphylococcal infections. CM4620 CM4620 (Zegocractin), is under investigation in multiple clinical trials, including NCT04195347 (pancreatitis due to asparaginase), NCT03709342 (PK/PD study in acute pancreatitis), NCT03401190 and NCT04681066 (pancreatitis and SIRS), and NCT04661540 (critical... Coelenteramide Not Available Conteltinib Conteltinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Conteltinib is a tyrosine kinase inhibitor. Conteltinib is under investigation in clinical... CP-547632 CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others. CP-778875 CP-778875 is under investigation in clinical trial NCT00326326 (Effect of CP-778,875 on HDL-C in Subjects With Abnormal Lipid Levels and Type 2 Diabetes.). Cresotamide Cresotamide is a small molecule drug. Cresotamide has a monoisotopic molecular weight of 151.06 Da. Cyclacillin For the treatment of bacterial infections caused by susceptible organisms. Cyclohexylformamide Not Available DA-6886 DA-6886 has been used in trials studying the treatment of Irritable Bowel Syndrome. Dabuzalgron Dabuzalgron is a small molecule drug. Dabuzalgron has a monoisotopic molecular weight of 317.06 Da. Dagrocorat Not Annotated Daltroban Daltroban is a small molecule drug. Daltroban has a monoisotopic molecular weight of 353.05 Da. Danavorexton Not Annotated Danegaptide Danegaptide has been investigated for the treatment of Focus of Study is STEMI. Danoprevir Danoprevir has been used in trials studying the treatment of Hepatitis C, Chronic. Danusertib Danusertib has been used in trials studying the treatment of Leukemia. Daporinad Daporinad has been used in trials studying the treatment of Melanoma, Cutaneous T-cell Lymphoma, and B-cell Chronic Lymphocytic Leukemia. Darexaban Darexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Dasabuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Dazopride Dazopride is a small molecule drug. The usage of the INN stem '-pride' in the name indicates that Dazopride is a sulpiride derivative and analogue. Dazopride has a monoisotopic molecular... Deacetoxycephalosporin C Not Available Declopramide Investigated for use/treatment in colorectal cancer and inflammatory bowel disease. Defactinib An inhibitor of FAK used alongside a MEK1/RAF inhibitor for the treatment of recurrent low-grade serous ovarian cancer. Deracoxib Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to... Diacetamate Diacetamate is a small molecule drug. Diacetamate has a monoisotopic molecular weight of 193.07 Da. Diamfenetide Diamfenetide is a small molecule drug. Diamfenetide has a monoisotopic molecular weight of 372.17 Da. Diapamide Diapamide is a small molecule drug. Diapamide has a monoisotopic molecular weight of 262.02 Da. Diazolidinylurea An ingredient used in hospitals for disinfection. Dibromsalan Dibromsalan is a small molecule drug. Dibromsalan has a monoisotopic molecular weight of 368.9 Da. Diclofenamide A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. Dicloxacillin A penicillin used to treat penicillinase-producing bacterial infections that are susceptible to the drug. Diethyltoluamide An insect repellant, also known as DEET. Diethyltryptamine Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine. Difamilast A phosphodiesterase-4 inhibitor used for the treatment of atopic dermatitis. Difenpiramide Not Annotated Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). DNK-333 Not Annotated Dobupride Dobupride is a small molecule drug. The usage of the INN stem '-pride' in the name indicates that Dobupride is a sulpiride derivative and analogue. Dobupride has a monoisotopic molecular... Dofetilide A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter. Domatinostat Not Annotated DONU Donu has been used in trials studying the treatment of Psychosis. Doramapimod Doramapimod is a P38 MAP kinase inhibitor. Doripenem An antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. Dorzolamide A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. Drinabant Investigated for use/treatment in alzheimer's disease, obesity, and schizophrenia and schizoaffective disorders. Dubermatinib Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL). Dulozafone Dulozafone is a small molecule drug. The usage of the INN stem '-zafone' in the name indicates that Dulozafone is a alozafone derivative. Dulozafone has a monoisotopic molecular weight of... E-7820 E7820 has been investigated for the treatment of Colon Cancer and Rectal Cancer. Ecabapide Ecabapide is a small molecule drug. Ecabapide has a monoisotopic molecular weight of 371.18 Da. Ecomustine Ecomustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Ecomustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. Ecomustine has a... Ecopladib Ecopladib is a small molecule drug. The usage of the INN stem '-pladib' in the name indicates that Ecopladib is a phospholipase A2 inhibitor. Ecopladib has a monoisotopic molecular weight... Edasalonexent Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes). Edonentan anhydrous Edonentan anhydrous is a small molecule drug. The usage of the INN stem '-entan' in the name indicates that Edonentan anhydrous is a endothelin receptor antagonist. Edonentan anhydrous has a... Eflucimibe Eflucimibe is a small molecule drug. Eflucimibe has a monoisotopic molecular weight of 469.3 Da. Elesclomol Investigated for use/treatment in melanoma. Elinogrel Investigated for use/treatment in cardiovascular disorders and myocardial infarction. Elmustine Elmustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Elmustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. Elmustine has a... Elsulfavirine Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact... Elubrixin Elubrixin has been used in trials studying the treatment of Cystic Fibrosis, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease (COPD). Encainide A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects. Encorafenib A kinase inhibitor used to treat unresectable or metastatic melanoma with BRAF mutations. Enobosarm Enobosarm has been used in trials studying the treatment of Stress Urinary Incontinence and Triple Negative Breast Cancer. Entinostat Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic... Entrectinib Entrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment... Enviroxime Enviroxime is a small molecule drug. Enviroxime has a monoisotopic molecular weight of 358.11 Da. Enzalutamide A second-generation androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer. Enzalutamide d3 Enzalutamide d3 is under investigation in clinical trial NCT03850795 (HC-1119 Versus Enzalutamide in Metastatic Castration-resistant Prostate Cancer (Mcrpc)). Epacadostat Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others. Epanolol Epanolol is an beta blocker. Eperezolid Eperezolid is a small molecule drug. The usage of the INN stem '-zolid' in the name indicates that Eperezolid is a oxazolidinone antibacterial. Eperezolid has a monoisotopic molecular weight of... Epicillin Not Annotated Eprotirome Investigated for use/treatment in hyperlipidemia, metabolic disease, and obesity. Eragidomide Eragidomide is under investigation in clinical trial NCT04297124 (A Study to Evaluate the Metabolism and Excretion of [14C]-CC-90009 in Healthy Male Subjects). Ertapenem A carbapenem antibiotic used for the treatment of moderate to severe infections caused by susceptible bacteria. Estradiol sulfamate Investigated for use/treatment in endometriosis. Etamivan Etamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States. Etersalate Etersalate is a small molecule drug. Etersalate has a monoisotopic molecular weight of 357.12 Da. Ethenzamide Not Annotated Ethoxzolamide For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy. Eticlopride Not Annotated Etidocaine Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage... Etiracetam Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)). Etofamide Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued . EVT 302 Investigated for use/treatment in smoking cessation. Exalamide Exalamide is a small molecule drug. Exalamide has a monoisotopic molecular weight of 221.14 Da. Fallypride Fallypride is under investigation in clinical trial NCT02310360 (Striatal and Extra-striatal Dopamine Release in Response to Food in Healthy Humans). Faropenem Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia. Faropenem medoxomil Investigated for use/treatment in bacterial infection, bronchitis, otitis media, and pediatric indications. Fasentin Not Annotated Fasitibant Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee). Fedratinib Fedratinib is indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis. Figopitant Figopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers). Fipaxalparant Not Annotated Firuglipel Firuglipel is a small molecule drug. Firuglipel is under investigation in clinical trial NCT02647320 (12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin). Firuglipel has a... FK-960 Investigated for use/treatment in dementia, alzheimer's disease, schizophrenia and schizoaffective disorders, and memory loss. Flomoxef Flomoxef has been used in trials studying the treatment of Urinary Tract Infection. Florasulam Florasulam is under investigation in clinical trial NCT01193465 (Temperature and Humidity Among Different Anesthesia Work-station). Flotufolastat F-18 A radiopharmaceutical diagnostic agent used in PET imaging to visualize PSMA-positive lesions in men with prostate cancer with suspected metastasis or recurrence. Fluazuron Fluazuron is a benzoyl phenylurea compound. Flucloxacillin A narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA). Flufenoxuron Flufenoxuron is under investigation in clinical trial NCT00922870 (Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock). Flumatinib Flumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic. Flurofamide Flurofamide is a small molecule drug. Flurofamide has a monoisotopic molecular weight of 217.04 Da. Flutamide An antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma. Fomidacillin Fomidacillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Fomidacillin is a antibiotic, 6-aminopenicillanic acid derivative. Fomidacillin has a monoisotopic molecular... Foretinib Foretinib has been used in trials studying the treatment of Cancer, Breast Cancer, Carcinoma, Renal Cell, Recurrent Breast Cancer, and Neoplasms, Head and Neck, among others. Foretinib is an orally... Fosamprenavir An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. Fosdagrocorat Fosdagrocorat has been used in trials studying the treatment and basic science of Rheumatoid Arthritis. Fotemustine An alkylating agent used in the treatment of metastatic melanoma. Frentizole Frentizole is a small molecule drug. Frentizole has a monoisotopic molecular weight of 299.07 Da. Frunexian Not Available Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. Fuzlocillin Fuzlocillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Fuzlocillin is a antibiotic, 6-aminopenicillanic acid derivative. Fuzlocillin has a monoisotopic molecular... GC-373 GC-373 is a peptide aldehyde which is metabolized from the bisulfide adduct, GC-376 free acid . It is an inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease... GC-376 free acid GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells . The compound... GDC-0349 GDC-0349 has been used in trials studying the treatment of Non-Hodgkin's Lymphoma, Solid Tumor. Gefapixant A P2X3 receptor antagonist that reduces the cough reflex in patients with refractory or unexplained chronic cough. Geldanamycin Not Available Giripladib Giripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee). Gisadenafil Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia. Glasdegib A sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy. Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. Glesatinib Investigated for use/treatment in cancer/tumors (unspecified). Glibornuride Glibornuride is a sulfonylurea-type anti-diabetic drug. Glicaramide Glicaramide is a small molecule drug. Glicaramide has a monoisotopic molecular weight of 598.29 Da. Gliclazide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Gliflumide Gliflumide is a small molecule drug. Gliflumide has a monoisotopic molecular weight of 500.19 Da. Glimepiride A sulfonylurea drug used to treat type 2 diabetes mellitus. Gliquidone A sulfonylurea drug used in the management of diabetes mellitus type 2. Glisentide Glisentide is a small molecule drug. Glisentide has a monoisotopic molecular weight of 445.17 Da. Glisolamide Glisolamide is a small molecule drug. Glisolamide has a monoisotopic molecular weight of 434.16 Da. Glisoxepide For the treatment of diabetes mellitus type 2. GLPG-0187 GLPG0187 has been used in trials studying the treatment of Solid Tumors. Glyburide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Glybuzole Glybuzole is a small molecule drug. Glybuzole has a monoisotopic molecular weight of 297.06 Da. Glyclopyramide Glyclopyramide is a small molecule drug. Glyclopyramide has a monoisotopic molecular weight of 303.04 Da. Glymidine Glycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. Granotapide Granotapide has been used in trials studying the treatment of Type II Diabetes Mellitus. Grapiprant The effects of grapiprant have been investigated in the area of analgesia and anti-inflammation due to the effects that have been reported about this molecule. This molecule has been approved... Grazoprevir An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. GSK-2981278 GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis). GSK-424887 Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and Anxiety Disorder. GTX-758 GTX-758 is under investigation in clinical trial NCT01420861 (GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer). GW-813893 Not Available H-89 Not Available Hetacillin Hetacillin is a beta-lactam antibiotic prodrug used to treat bacterial infections. In the body it gets converted to ampicillin. Hippuric acid Not Annotated HMN-214 Not Annotated HQP1351 HQP1351 is under investigation in clinical trial NCT03883100 (A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation). Hydrochlorothiazide A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. Hydroflumethiazide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. Hydroxyurea An antimetabolite used to treat sickle cell anemia crisis, resistant chronic myeloid leukemia, and Locally advanced squamous cell carcinomas of the head and neck (excluding the lip). Ibipinabant Ibipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes. Ibrigampar Investigated for use/treatment in diabetes mellitus type 2. Ibrolipim Ibrolipim is a small molecule drug. Ibrolipim has a monoisotopic molecular weight of 450.03 Da. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Ibutilide A class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion. ICI-164384 Not Available IDD594 Not Available Iguratimod Iguratimod is under investigation in Rheumatoid Arthritis. Ilorasertib Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others. Imatinib A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. IMD-0354 Not Annotated Imidocarb Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites. Imidurea Imidurea is an antimicrobial preservative used in cosmetics. It acts as a formaldehyde releaser. Imipenem A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. INCB13739 Investigated for use/treatment in diabetes mellitus type 2 and diabetes prevention. INCB3284 Investigated for use/treatment in inflammatory disorders (unspecified). Indapamide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. Indibulin Investigated for use/treatment in solid tumors. Indisulam Investigated for use/treatment in lung cancer. Indoramin Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action. Infigratinib An FGFR inhibitor used to treat locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) rearrangement. Iniparib Not Annotated Inosine pranobex A medication used to treat subacute sclerosing panencephalitis. Iobenzamic acid Not Annotated Iodohippuric acid Iodohippuric acid is under investigation in clinical trial NCT02599844 (Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults). Iofolastat I-123 Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer). Ioforminol Ioforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH With or Without PCI. Iolopride I-123 Iolopride I-123 is a small molecule drug. The usage of the INN stem '-pride' in the name indicates that Iolopride I-123 is a sulpiride derivative and analogue. Iolopride I-123 has... IPI-493 IPI-493 has been used in trials studying the treatment of Advanced Malignancies. Isoindolin-1,3-Dithione Not Annotated Isopenicillin N Not Available Ispinesib Investigated for use/treatment in breast cancer, lung cancer, solid tumors, renal cell carcinoma, pediatric indications, ovarian cancer, and head and neck cancer. Itopride An acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia such as nausea and vomiting. JNJ-26489112 JNJ-26489112 is under investigation in clinical trial NCT00579384 (A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy). JNJ-41443532 JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2. JTC-801 free base An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment. K-134 K-134 has been used in trials studying the treatment of Intermittent Claudication. KD3010 Investigated for use/treatment in metabolic disease and obesity. KRN-633 Not Annotated KX-2361 Not Annotated Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Lacosamide An antiepileptic drug used to treat partial-onset seizures and primary generalized tonic-clonic seizures. Ladarixin Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function). Lafutidine Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD). Landiolol A rapid-acting selective beta-blocker used to reduce ventricular rate in supraventricular tachycardia in adults. Lanifibranor Lanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337). Laromustine Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), colorectal cancer, leukemia (lymphoid), leukemia (myeloid), lung cancer, myelodysplastic syndrome, pediatric indications, and solid tumors. Lasmiditan An oral 5HT1F agonist used for the acute treatment of migraine headache with or without aura. Latamoxef Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,... Lecimibide Lecimibide is a small molecule drug. Lecimibide has a monoisotopic molecular weight of 590.29 Da. Lenacapavir A first-in-class capsid inhibitor being investigated for use in HIV-1 treatment. Lenampicillin Lenampicillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Lenampicillin is a antibiotic, 6-aminopenicillanic acid derivative. Lenampicillin has a monoisotopic molecular... Lenvatinib A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. Levetiracetam A novel anticonvulsant agent used as an adjunct medication to manage partial onset, myoclonic, and generalized tonic-clonic seizures in patients with epilepsy. Levobupivacaine A drug used for nerve block and anesthesia. Levosulpiride indicated to treat dyspepsia, symptoms of Meniere's syndrome, and second line in the treatment of drug-induced nausea and vomiting. LGD-6972 LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus). Lidamidine Lidamidine is a small molecule drug. Lidamidine has a monoisotopic molecular weight of 220.13 Da. Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Linezolid An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. Linifanib Investigated for use/treatment in leukemia (myeloid), myelodysplastic syndrome, and solid tumors. Linrodostat Linrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants). Litronesib Litronesib has been used in trials studying the treatment of Solid Tumors, Ovarian Cancer, Gastric Cancer, Prostate Cancer, and Acute Leukaemia, among others. Lixivaptan Investigated for use/treatment in hyponatremia and congestive heart failure. Lomustine An alkylating agent used as a part of chemotherapeutic regimens for the treatment of primary and metastatic brain tumors as well as refractory or relapsed Hodgkin's disease in addition to surgical and/or radiotherapeutic treatments. Loracarbef Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,... Lorcainide Not Annotated Lorlatinib An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. Lozilurea Lozilurea is a small molecule drug. Lozilurea has a monoisotopic molecular weight of 212.07 Da. Lufenuron Lufenuron is used in veterinary for the control of flea. LY-295501 ILX-295501 has been used in trials studying the treatment of Ovarian Cancer, Metastatic Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cavity Cancer. LY-3009120 Not Annotated m-Hydroxyhippuric acid Not Available Macitentan An endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression. Mafenide An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Masitinib Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the... Mebenil An obsolete fungicide used to control various pathogens on cereals and seed potatoes. Mefruside Not Annotated Meglitinide Meglitinide is a small molecule drug. Meglitinide has a monoisotopic molecular weight of 333.08 Da. Meloxicam An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. Mepivacaine A local anesthetic used for local or regional analgesia or anesthesia. Merimepodib For the treatment of hepatitis C virus (HCV) infection. Meropenem A carbapenem antibiotic used to treat a wide variety of infections in the body. Mesosulfuron-methyl Mesosulfuron-methyl is under investigation in clinical trial NCT01118117 (A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery). Metabromsalan Not Annotated Metahexamide Not Annotated Metampicillin Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the... Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. Methfuroxam Methfuroxam is under investigation in clinical trial NCT01213407 (Dendritic Cell Cancer Vaccine for High-grade Glioma). Metiamide Potential in the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion. Meticillin Used to treat infections caused by susceptible Gram-positive bacteria, particularly beta-lactamase-producing organisms such as Staphylococcus aureus that would otherwise be resistant to most penicillins. Metoclopramide An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. Metolazone A thiazide-like diuretic used to treat hypertension. Mezlocillin Used to treat serious gram–negative infections of the lungs, urinary tract, and skin. Mibampator Mibampator has been used in trials studying the treatment of Alzheimer's Disease. Milacemide Milacemide is a small molecule drug. Milacemide has a monoisotopic molecular weight of 144.13 Da. Mirabegron A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity. Mirdametinib A kinase inhibitor used to treat neurofibromatosis type 1 in children and adults. Mirodenafil Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction. Mivebresib Mivebresib is a small molecule drug. The usage of the INN stem '-bresib' in the name indicates that Mivebresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family... MK-0686 MK0686 has been used in trials studying the treatment of Osteoarthritis, Pain, Postoperative, and Neuralgia, Postherpetic. MK-8033 Not Annotated Mocetinostat Mocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others. Moclobemide A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. Momelotinib A Janus Kinase inhibitor used to treat intermediate or high-risk myelofibrosis. Mosapride A prokinetic 5-HT4 receptor agonist used to stimulate gastric motility. Mozenavir Not Available N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide Not Available N-(Benzoylcarbamoyl)-beta-D-glucopyranosylamine Not Available N-6022 N6022 has been used in trials studying the treatment of Asthma and Cystic Fibrosis. N-acetyl-N'-beta-D-glucopyranosyl urea Not Available N-Benzylformamide Not Available N-phenylthiourea Not Available N,N-dimethylformamide Not Available Nacubactam Nacubactam is under investigation in clinical trial NCT03174795 (A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection). Nafcillin A penicillin derivative antibiotic used to treat susceptible staphylococcal infections. Naluzotan Investigated for use/treatment in anxiety disorders and depression. Narlaprevir Not Annotated Naronapride Investigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis. Navarixin Navarixin has been investigated for the treatment of Asthma. Navitoclax Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is... NCX 701 Investigated for use/treatment in pain (acute or chronic). Nebentan Nebentan is a small molecule drug. The usage of the INN stem '-entan' in the name indicates that Nebentan is a endothelin receptor antagonist. Nebentan has a monoisotopic molecular weight... Nelotanserin Nelotanserin has been used in trials studying the treatment of Lewy Body Dementia, Visual Hallucinations, Dementia With Lewy Bodies, and REM Sleep Behavior Disorder. It is a highly selective antagonist... Nemonapride Not Annotated Nepafenac An ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. Nesbuvir Nesbuvir has been investigated for the treatment of Hepatitis C. Netazepide Netazepide has been used in trials studying the prevention and treatment of Dyspepsia, Hypergastrinaemia, Barrett's Esophagus, ECL-cell Hyperplasia, and Rebound Hyperacidity, among others. Netupitant An antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy. Nevanimibe Nevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome). Nicarbazin Not Annotated Niclosamide An anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children. Nimesulide A cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. Nimustine Nimustine has been used in trials studying the treatment of Glioblastoma. Niravoline Niravoline is a small molecule drug. Niravoline has a monoisotopic molecular weight of 379.19 Da. Nirmatrelvir An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19. Nitrocefin Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin... Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Noxytiolin Local antibacterial that probably acts by releasing formaldehyde in aqueous solutions. It is used for THERAPEUTIC IRRIGATION of infected body cavities - bladder, peritoneum, etc. and as a spray for... NRC-AN-019 Not Annotated NS-3728 Investigated for use/treatment in anemia (sickle cell) and cancer/tumors (unspecified). NS-398 NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases. Nupafant Nupafant is a small molecule drug. The usage of the INN stem '-pafant' in the name indicates that Nupafant is a platelet-activating factor antagonist. Nupafant has a monoisotopic molecular weight... Oclacitinib Not Annotated Olorofim Olorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects). Ombitasvir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Omecamtiv Mecarbil Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among others. Omipalisib Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis. Onalespib Investigated for use/treatment in cancer/tumors (unspecified). ORC-13661 ORC-13661 is under investigation in clinical trial NCT05730283 (Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin). Orludodstat Orludodstat is a small molecule drug. The usage of the INN stem '-dodstat' in the name indicates that Orludodstat is a dihydro-orotate dehydrogenase (DHODH) inhibitor. Orludodstat is under investigation in... Oseltamivir A neuraminidase inhibitor used in the prophylaxis and treatment of influenza. Oseltamivir acid Not Available Osimertinib A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma. Oxacillin A penicillin antibiotic used to treat a number of susceptible bacterial infections. Oximonam Oximonam is a small molecule drug. The usage of the INN stem '-monam' in the name indicates that Oximonam is a monobactam antibiotic. Oximonam has a monoisotopic molecular weight of... Oxyclozanide Oxyclozanide is a small molecule drug. Oxyclozanide has a monoisotopic molecular weight of 398.88 Da. p-Toluenesulfonamide Not Available Padnarsertib Not Annotated Palosuran Palosuran is a small molecule drug. The usage of the INN stem '-osuran' in the name indicates that Palosuran is a urotensin receptor antagonist. Palosuran has a monoisotopic molecular weight... Pamufetinib Pamufetinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Pamufetinib is a tyrosine kinase inhibitor. Pamufetinib is under investigation in clinical... Parapropamol Parapropamol is a small molecule drug. Parapropamol has a monoisotopic molecular weight of 165.08 Da. Paratoulene phosphate Not Available Paritaprevir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Parsalmide Parsalmide is a small molecule drug. Parsalmide has a monoisotopic molecular weight of 246.14 Da. Pavinetant Pavinetant has been used in trials studying the basic science and treatment of Safety and Schizophrenia. Pazopanib An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy. PC-786 Not Annotated PCI-27483 PCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer. Penamecillin Not Annotated Penimepicycline Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification... Pesampator PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural. Pexmetinib Pexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab or Ipilimumab). PF-00489791 PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic Nephropathies, Hypertension, Pulmonary, and Peripheral Vascular Disease. PF-00610355 PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others. PF-03715455 PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive, and Chronic Obstructive Pulmonary Disease (COPD). PF-04457845 PF-04457845 is under investigation in Fear Conditioning. PF-04457845 has been investigated for the treatment of Tourette Syndrome and Cannabis Dependence. PF-05089771 PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee). PF-06282999 Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects). PF-5212372 PF-5212372 is under investigation in clinical trial NCT02795832 (A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis). PF-562271 Not Annotated PH-797804 PH-797804 has been investigated for the treatment of Osteoarthritis. Phenacemide Used to control certain seizures in the treatment of epilepsy. Phenacetin Used principally as an analgesic. Pheneturide Not Annotated Phenoxymethylpenicillin A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. Phthalylsulfathiazole A sulfonamide antibacterial indicated in the treatment of gastrointestinal infections. Piclamilast Piclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as... Picobenzide Picobenzide is a small molecule drug. Picobenzide has a monoisotopic molecular weight of 240.13 Da. Pictilisib Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others. Piflufolastat F 18 A radiopharmaceutical diagnostic agent used with PET to image PSMA-positive lesions for the diagnosis of metastatic or recurrent prostate cancer. PIK-75 PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor. Pilaralisib Pilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors,... Pilsicainide Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation. Pimavanserin A second generation atypical antipsychotic used for the treatment of hallucinations and delusions caused by Parkinson's Disease. Pimitespib TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors). Pincainide Pincainide is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Pincainide is a class I antiarrhythmic, procainamide and lidocaine derivative. Pincainide has... Piperacillin A penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam susceptible, β-lactamase generating strains of several bacteria. Piperine Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders. Piracetam A nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer. Piragliatin Piragliatin is a small molecule drug. The usage of the INN stem '-gliatin' in the name indicates that Piragliatin is a glucokinase activator. Piragliatin has a monoisotopic molecular weight of... Pirbenicillin Pirbenicillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Pirbenicillin is a antibiotic, 6-aminopenicillanic acid derivative. Pirbenicillin has a monoisotopic molecular... Piretanide A loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin. Pivampicillin An ampicillin prodrug used to treat a variety of infections. Pivmecillinam A prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs). PKI-179 PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors. Platensimycin Not Available Plixorafenib PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors). PLX-4720 Not Available Polmacoxib Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee. Polythiazide A thiazide diuretic used in the management of hypertension and treatment of edema. Practolol Used in the emergency treatment of cardiac arrhythmias. Prazocillin Prazocillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Prazocillin is a antibiotic, 6-aminopenicillanic acid derivative. Prazocillin has a monoisotopic molecular... Presatovir Presatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections. Prilocaine A local anesthetic used in dental procedures. Pritelivir Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes. Probenecid A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia. Procainamide A medication used to treat life threatening ventricular arrhythmias. Procaine benzylpenicillin A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Procarbazine An antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents. Propacetamol Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. Propicillin Not Annotated PXS-4728A free base PXS-4728A free base is under investigation in clinical trial NCT05904717 (Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder). Pyrotinib Pyrotinib is under investigation in clinical trial NCT03756064 (Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer). Pyrrocaine Pyrrocaine is a small molecule drug. The usage of the INN stem '-caine' in the name indicates that Pyrrocaine is a local anaesthetic. Pyrrocaine has a monoisotopic molecular weight of... Quinacillin Quinacillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Quinacillin is a antibiotic, 6-aminopenicillanic acid derivative. Quinacillin has a monoisotopic molecular... Quinethazone Used to treat hypertension. Quizartinib A FLT3 inhibitor used in combination with cytarabine and anthracycline to treat acute myeloid leukemia with FLT3 internal tandem duplication R-95845 R-95845 is an inhibitor of HIV-1 reverse transcriptase. Rabusertib Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer. Raclopride Raclopride has been used in trials studying Parkinson Disease. Radiprodil Radiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain. Radotinib Radotinib is indicated for the treatment of different types of cancer, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other Bcr-Abl tyrosine-kinase inhibitors, such... Rafoxanide Rafoxanide is a small molecule drug. Rafoxanide has a monoisotopic molecular weight of 624.82 Da. Ramatroban Ramatroban has been used in trials studying the treatment of Asthma. Ranimustine Not Annotated Razupenem Razupenem has been used in trials studying the treatment of Skin Infections. Recainam Recainam is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Recainam is a class I antiarrhythmic, procainamide and lidocaine derivative. Recainam has... Redaporfin Not Available Refametinib Investigated for use/treatment in cancer/tumors (unspecified). Regorafenib A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma. Relenopride Relenopride has been used in trials studying the treatment of Chronic Idiopathic Constipation. Relugolix An oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer. Remacemide Investigated for use/treatment in epilepsy, huntington's disease, and parkinson's disease. Remoxipride An discontinued atypical antipsychotic selective for dopamine D2 receptors. Renzapride For the treatment of constipation-predominant irritable bowel syndrome (IBS-C). Reparixin Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type 1, and Pancreatic... Resatorvid Investigated for use/treatment in sepsis and septicemia. Resminostat Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others. Resorantel Resorantel is a small molecule drug. The usage of the INN stem '-antel' in the name indicates that Resorantel is a anthelminthic. Resorantel has a monoisotopic molecular weight of 306.98... Retaspimycin Investigated for use/treatment in gastric cancer, lung cancer, and multiple myeloma. Revefenacin An anticholinergic agent used to treat COPD. Revumenib A small molecule menin inhibitor for the treatment of relapsed/refractory leukemia with KMT2A translocation. RG-2833 Not Annotated Rgb-286638 free base Not Annotated Rifampin An antibiotic used alone or in combination with other antimicrobial drugs to treat tuberculosis and asymptomatic carriers of Neisseria meningitidis. Rilapladib Investigated for use/treatment in atherosclerosis and cardiovascular disorders. Ripasudil A rho kinase inhibitor indicated to treat ocular hypertension and open-angle glaucoma. Ripretinib A kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST). Risotilide Risotilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Risotilide is a sematilide derivative class III antiarrhythmic. Risotilide has a monoisotopic... Ritipenem Ritipenem is a small molecule drug. Ritipenem has a monoisotopic molecular weight of 288.04 Da. RO-4987655 RO4987655 has been used in trials studying the treatment of Neoplasms. Rociletinib Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer. Roflumilast A selective phosphodiesterase-4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) and to treat skin conditions such as plaque psoriasis and atopic dermatitis. Ropivacaine An amide-type local anesthetic used for local or regional anesthesia during surgery and for short-term management of acute pain. Rosuvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. RSV-604 RSV-604 is under investigation in clinical trial NCT00416442 (Safety, Tolerability and Pharmacokinetic Study of Single and Multiple Intravenous Doses of RSV604 in Healthy Subjects.). S-23 An androgen receptor modulator. S-38093 Not Annotated S-Ethylisothiourea S-Ethylisothiourea is a nitric oxide synthase inhibitor. Safotibant Safotibant is a small molecule drug. The usage of the INN stem '-tibant' in the name indicates that Safotibant is a bradykinin receptor antagonist. Safotibant has a monoisotopic molecular weight... Salicylamide Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... Salicylamide O-acetic acid A salicylate indicated in combination with local anesthetics and corticosteroids for short term treatment of inflammation. Salicylanilide Not Annotated Salicylhydroxamic Acid Not Available Sanfetrinem Sanfetrinem is a small molecule drug. Sanfetrinem has a monoisotopic molecular weight of 281.13 Da. Sanfetrinem cilexetil Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability of Sanfetrinem Cilexetil). SAR-125844 SAR-125844 is under investigation in clinical trial NCT01391533 (Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors). Saredutant Investigated for use/treatment in depression and anxiety disorders. SB-269970 SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist... SB-705498 SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis. SB-743921 Investigated for use/treatment in cancer/tumors (unspecified) and lymphoma (non-hodgkin's). SC-236 SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , . SC-74020 Not Available Seclidemstat Not Annotated Selexipag A non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension. Selonsertib Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis). Semapimod Semapimod has been used in trials studying the treatment of Crohn Disease. Sematilide Sematilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Sematilide is a sematilide derivative class III antiarrhythmic. Sematilide has a monoisotopic... Sembragiline Sembragiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Sembragiline is a monoamine oxydase (MAO)-inhibitor type B. Sembragiline has a monoisotopic... Semustine Not Annotated Senicapoc Investigated for use/treatment in anemia (sickle cell) and asthma. Sildenafil A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. Silver sulfadiazine A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. Sirpiglenastat Sirpiglenastat, also known as DRP-104, is a prodrug of 6-diazo-5-oxo-L-norleucine (DON), which is a broad-acting glutamine antagonist. It is under investigation in clinical trial NCT04471415 (Study to Investigate DRP-104 in... Sitravatinib Sitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma). Sivelestat Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult. SKF-91488 Not Available SLC-0111 Not Available SLV319 Investigated for use/treatment in obesity. SLx-4090 Investigated for use/treatment in hyperlipidemia. SNS-314 Investigated for use/treatment in solid tumors. SNX-5422 Investigated for use/treatment in cancer/tumors (unspecified). Sonepiprazole Sonepiprazole is a small molecule drug. The usage of the INN stem '-prazole' in the name indicates that Sonepiprazole is a benzimidazole derivative antiulcer medication. Sonepiprazole has a monoisotopic molecular... Sorafenib A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma. SP-8203 SP-8203 has been used in trials studying the treatment of Ischemic Stroke. Sparsentan An endothelin and angiotensin II receptor antagonist indicated to reduce proteinuria in adults with primary immunoglobulin A nephropathy at risk of rapid disease progression. Spebrutinib Spebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell. Streptozocin A nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma. Succinylsulfathiazole Not Annotated Sulbactam An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. Sulbactam pivoxil A prodrug of a beta-lactamase inhibitor used to improve the efficacy of beta lactam antibiotics Sulbenicillin Not Annotated Sulfabenzamide A sulfonamide antibacterial used as an ingredient in various topical and vaginal preparations to treat certain infections, but has been discontinued by the FDA. Sulfacarbamide Sulfacarbamide is a small molecule drug. Sulfacarbamide has a monoisotopic molecular weight of 215.04 Da. Sulfacetamide A sulfonamide used to treat inflammatory ocular conditions and acne vulgaris. Sulfachlorpyridazine A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine. Sulfaclomide Sulfaclomide is a small molecule drug. Sulfaclomide has a monoisotopic molecular weight of 312.04 Da. Sulfaclozine Sulfaclozine is a small molecule drug. Sulfaclozine has a monoisotopic molecular weight of 284.01 Da. Sulfacytine Used orally in the treatment of acute urinary tract infections. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Sulfadimethoxine For use in the treatment of infections. Sulfadoxine A long acting sulfonamide used for the treatment or prevention of malaria. Sulfaethoxypyridazine Not Annotated Sulfaguanidine Sulfaguanidine is a sulfonamide antibiotic with antimicrobial and antibacterial activities. Sulfaisodimidine Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has... Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Sulfamethazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Sulfamethoxypyridazine A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis. Sulfametopyrazine An antibiotic used in the treatment or prevention of bacterial infections and malaria. Sulfametrole An antibiotic indicated in combination intravenous products for various bacterial infections. Sulfamoxole For the treatment of bacterial infection. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfanitran Not Annotated Sulfaphenazole For the treatment bacterial infections. Sulfaproxyline Sulfaproxyline is a small molecule drug. Sulfaproxyline has a monoisotopic molecular weight of 334.1 Da. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Sulfaquinoxaline Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K... Sulfasalazine A salicylate used to treat Crohn's disease, ulcerative colitis, and rheumatoid arthritis. Sulfasymazine Sulfasymazine is a small molecule drug. Sulfasymazine has a monoisotopic molecular weight of 307.11 Da. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Sulfathiourea Not Annotated Sulfatolamide Not Annotated Sulfatroxazole Sulfatroxazole is a small molecule drug. Sulfatroxazole has a monoisotopic molecular weight of 267.07 Da. Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Sulofenur Sulofenur is a small molecule drug. Sulofenur has a monoisotopic molecular weight of 350.05 Da. Sulopenem Sulopenem is a penem antibacterial. It is marketed as the prodrug sulopenem etzadroxil in combination with probenecid. Sulotroban Sulotroban is a small molecule drug. Sulotroban has a monoisotopic molecular weight of 335.08 Da. Sulpiride A selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia. Sultamicillin A mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria. Sulthiame A carbonic anhydrase inhibitor used primarily in benign focal epilepsies of childhood that may be useful as an adjunct therapy in a variety of other refractory epilepsies. Sultopride Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics . Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Suncillin Suncillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Suncillin is a antibiotic, 6-aminopenicillanic acid derivative. Suncillin has a monoisotopic molecular... Sunvozertinib A tyrosine kinase inhibitor used to treat adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations. Surufatinib Surufatinib is under investigation in clinical trial NCT02588170 (Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors). Susalimod Susalimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Susalimod is a immunomodulator, both stimulant/suppressive and stimulant. Susalimod has a monoisotopic... Sutezolid Sutezolid has been used in trials studying the treatment of Tuberculosis. T-900607 T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer. Tacedinaline Tacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer. Tagorizine Tagorizine is a small molecule drug. The usage of the INN stem '-rizine' in the name indicates that Tagorizine is a antihistaminic/cerebral (or peripheral) vasodilator. Tagorizine has a monoisotopic molecular... TAK-243 TAK-243 is under investigation in clinical trial NCT03816319 (TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia). TAK-715 TAK-715 is under investigation in clinical trial NCT00760864 (Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis). Talampicillin Not Annotated Tamsulosin An alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction. Tanespimycin Investigated for use/treatment in leukemia (myeloid) and solid tumors. Tanimilast CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease. Taprenepag Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle. Taprizosin Taprizosin is a small molecule drug. Taprizosin has a monoisotopic molecular weight of 506.17 Da. Tasisulam Tasisulam has been used in trials studying the treatment and basic science of Melanoma, Lymphoma, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others. Tauromustine Tauromustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Tauromustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. Tauromustine has a... Tazemetostat A methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. Tazobactam A beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. Tebipenem pivoxil An oral carbapenem antibacterial indicated for complicated urinary tract infections, including pyelonephritis, caused by susceptible Enterobacterales and Enterococcus faecalis in adults with limited or no alternative oral treatment options. Tecovirimat An antiviral medication used to treat smallpox, monkeypox, and cowpox. Tefinostat Tefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)). Telaglenastat Telaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors). Temanogrel For the treatment and prophylaxis of arterial thrombosis. Temgicoluril Not Annotated Temocillin Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. Tersolisib STX-478 is under investigation in clinical trail NCT05768139 (First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors). Thiambutosine Thiambutosine is a small molecule drug. Thiambutosine has a monoisotopic molecular weight of 343.17 Da. Thiocitrulline Not Available Ticalopride Investigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis. Ticarcillin A beta lactam antibiotic used to treat a variety of infections in the body. Tigemonam Tigemonam is a small molecule drug. The usage of the INN stem '-monam' in the name indicates that Tigemonam is a monobactam antibiotic. Tigemonam has a monoisotopic molecular weight of... Tilmacoxib Tilmacoxib is a small molecule drug. The usage of the INN stem '-coxib' in the name indicates that Tilmacoxib is a selective cyclo-oxygenase inhibitor. Tilmacoxib has a monoisotopic molecular weight... Tipranavir A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. Tipranavir C-14 Tipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects). Tirbanibulin A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp. Tivozanib A kinase inhibitor to treat adult patients with renal cell carcinoma (RCC) who have failed prior systemic therapies or experienced relapsed disease. TMC-310911 TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections.... TMC-647055 TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, and Chronic Hepatitis C Virus. TO-901317 TO-901317 is an LXRalpha and LXRbeta agonist. Tocainide An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. Tolazamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Tolbutamide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Tonabersat Investigated for use/treatment in migraine and cluster headaches. Tosifen Tosifen is a small molecule drug. Tosifen has a monoisotopic molecular weight of 332.12 Da. Trametinib A kinase inhibitor used alone or in combination with dabrafenib to treat patients with cancers with specific BRAF mutations, such as melanoma and non-small cell lung cancer. Trecetilide Trecetilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Trecetilide is a sematilide derivative class III antiarrhythmic. Trecetilide has a monoisotopic... Tribromsalan Tribromsalan is a small molecule drug. Tribromsalan has a monoisotopic molecular weight of 446.81 Da. Triclocarban An antibacterial agent used in liquid soaps and body washes. Triflumidate Triflumidate is a small molecule drug. Triflumidate has a monoisotopic molecular weight of 401.05 Da. Trimethobenzamide An antiemetic used to treat postoperative nausea and vomiting and nausea associated with gastroenteritis. TTI-101 Not Annotated Tucidinostat Investigated for use/treatment in cancer/tumors (unspecified). UC-781 Investigated for use/treatment in HIV infection. Udenafil A PDE5 inhibitor used to treat erectile dysfunction. Upamostat Upamostat has been used in trials studying the treatment of Pancreatic Cancer. Urea A keratolytic emollient used to treat hyperkeratotic lesions and moisturize the skin. Valdecoxib A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. Vaniprevir Vaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C... Vemurafenib A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. Venetoclax A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. Veralipride Not Annotated Vercirnon Vercirnon is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. It is... Verdinexor Kpt 335 is under investigation in clinical trial NCT02431364 (Trial of Safety and Tolerability of Oral Verdinexor (Verdinexor) in Healthy Adults). Vidupiprant Vidupiprant has been used in trials studying the treatment and basic science of Asthma. Vismodegib A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. Vistusertib Vistusertib is under investigation for the treatment of Advanced Gastric Adenocarcinoma. VLX-1005 Not Annotated VM4-037 VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037). Vonoprazan A potassium-competitive acid blocker used in the treatment of acid-related disorders and as an adjunct to Helicobacter pylori eradication. Vorinostat A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. Voxilaprevir A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. Voxtalisib Voxtalisib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Breast Cancer, among others. VX-148 Investigated for use/treatment in autoimmune diseases, psoriasis and psoriatic disorders, and viral infection. VX-702 Investigated for use/treatment in coronary artery disease, inflammatory disorders (unspecified), and rheumatoid arthritis. WAY-151693 Not Available Xipamide A diuretic indicated in the treatment of edema. XL765 For the treatment of various forms of cancer. Y-33075 Not Annotated Zafirlukast A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. Zaleplon A sedative used for short term treatment of insomnia in adults. Zidebactam A diazabicyclooctane beta-lactamase inhibitor and PBP2-binding antibacterial, used only with cefepime, indicated for complicated urinary tract infections including pyelonephritis caused by susceptible Gram-negative pathogens. Zileuton A leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma. Zimlovisertib PF-06650833 is under investigation in clinical trial NCT02609139 (Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects). Zinviroxime Zinviroxime is a small molecule drug. Zinviroxime has a monoisotopic molecular weight of 358.11 Da. Zoalene Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry. Zongertinib Zongertinib is an orally bioavailable, selective tyrosine kinase inhibitor that irreversibly targets activating HER2 mutations, including exon 20 insertions, used to inhibit downstream oncogenic signaling in patients with HER2-mutant non-small cell lung cancer. Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.