Name
Amides
Accession Number
DBCAT000494
Description

Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed)

ATC Classification
Drugs
DrugDrug Description
LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.
PrilocaineA local anesthetic used in dental procedures.
EtidocaineEtidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage...
LevobupivacaineA drug used for nerve block and anesthesia.
ButanilicaineNot Annotated
OseltamivirA neuraminidase inhibitor used in the prophylaxis and treatment of influenza.
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
AztreonamA beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria.
SulpirideA selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia.
RemoxiprideAn discontinued atypical antipsychotic selective for dopamine D2 receptors.
AmpicillinA penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
PhenoxymethylpenicillinA penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues.
CeftazidimeAn injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others.
CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
FlutamideAn antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
CinchocaineAn anesthetic used for local or regional anesthesia.
CephalexinA first generation cephalosporin used to treat certain susceptible bacterial infections.
SulfamethizoleA sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
LabetalolAn alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
LinezolidAn oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria.
SumatriptanA serotonin receptor agonist used to treat migraines and cluster headaches.
FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
DorzolamideA carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
BimatoprostA prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
CeruleninFor use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals
RifampicinAn antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis.
BenzylpenicillinA penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
BicalutamideAn androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
CloxacillinAn antibiotic agent used for the treatment of beta-hemolytic streptococcal and pneumococcal infections as well as staphylococcal infections.
BrinzolamideA carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
LevetiracetamA novel anticonvulsant agent used as an adjunct medication to manage partial onset, myoclonic, and generalized tonic-clonic seizures in patients with epilepsy.
CeftriaxoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
DarunavirA HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
CeftizoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.
ImipenemA carbapenem antibiotic normally administered with cilastatin to treat a variety of infections.
TazobactamA beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
TicarcillinA beta lactam antibiotic used to treat a variety of infections in the body.
TirbanibulinA tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp.
AmisulprideA dopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults.
PazopanibAn antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
NepafenacAn ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery.
MirabegronA beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity.
MacitentanAn endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression.
CeftolozaneA cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia.
TriclocarbanAn antibacterial agent used in liquid soaps and body washes.
SelexipagA non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
VenetoclaxA BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
AcalabrutinibA Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma.
LasmiditanAn oral 5HT1F agonist used for the acute treatment of migraine headache with or without aura.
RevefenacinAn anticholinergic agent used to treat COPD.
EntrectinibEntrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment...
LorlatinibAn anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
FedratinibFedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk.
GrapiprantThe effects of grapiprant have been investigated in the area of analgesia and anti-inflammation due to the effects that have been reported about this molecule. This molecule has been approved...
TazemetostatA methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
RopivacaineAn analgesic drug used for local or regional anesthesia for surgery and short-term management of pain.
MepivacaineA local anesthetic used for local or regional analgesia or anesthesia.
ArticaineA local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures.
AfatinibAn antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy.
CefiderocolA cephalosporin antibiotic used in complicated urinary tract infections.
EticloprideNot Annotated
CapmatinibA kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping.
PF-06650833PF-06650833 is under investigation in clinical trial NCT02609139 (Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects).
NirmatrelvirAn oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19.
PiperacillinA penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria.
TrimethobenzamideAn antiemetic used to treat postoperative nausea and vomiting and nausea associated with gastroenteritis.
HetacillinHetacillin is a beta-lactam antibiotic prodrug used to treat bacterial infections. In the body it gets converted to ampicillin.
Benzylpenicilloyl polylysineA penicillin derivative used to determine penicillin allergies.
ZaleplonA sedative used for short term treatment of insomnia in adults.
AmdinocillinUsed in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms.
BacampicillinAn ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections.
PivmecillinamA prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs).
RoflumilastA selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis.
PiclamilastPiclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as...
Oseltamivir acidNot Available
AcetamideNot Available
3-MethoxybenzamideNot Available
4-FluorobenzylamineNot Available
Isopenicillin NNot Available
1-(4-Amidinophenyl)-3-(4-Chlorophenyl)UreaNot Available
RenzaprideFor the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
ItoprideAn acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia such as nausea and vomiting.
ADL5859Investigated for use/treatment in pain (acute or chronic).
AsimadolineInvestigated for use/treatment in irritable bowel syndrome (IBS).
RilapladibInvestigated for use/treatment in atherosclerosis and cardiovascular disorders.
INCB3284Investigated for use/treatment in inflammatory disorders (unspecified).
APD791For the treatment and prophylaxis of arterial thrombosis.
NaronaprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
SB-743921Investigated for use/treatment in cancer/tumors (unspecified) and lymphoma (non-hodgkin's).
BedoradrineInvestigated for use/treatment in asthma and labor and delivery.
Faropenem medoxomilInvestigated for use/treatment in bacterial infection, bronchitis, otitis media, and pediatric indications.
SLx-4090Investigated for use/treatment in hyperlipidemia.
SNX-5422Investigated for use/treatment in cancer/tumors (unspecified).
IndibulinInvestigated for use/treatment in solid tumors.
IspinesibInvestigated for use/treatment in breast cancer, lung cancer, solid tumors, renal cell carcinoma, pediatric indications, ovarian cancer, and head and neck cancer.
SenicapocInvestigated for use/treatment in anemia (sickle cell) and asthma.
OnalespibInvestigated for use/treatment in cancer/tumors (unspecified).
TucidinostatInvestigated for use/treatment in cancer/tumors (unspecified).
AvasimibeInvestigated for use/treatment in peripheral vascular disease.
RemacemideInvestigated for use/treatment in epilepsy, huntington's disease, and parkinson's disease.
FK-960Investigated for use/treatment in dementia, alzheimer's disease, schizophrenia and schizoaffective disorders, and memory loss.
TonabersatInvestigated for use/treatment in migraine and cluster headaches.
AgomelatineAgomelatine is indicated to treat major depressive episodes in adults.
SaredutantInvestigated for use/treatment in depression and anxiety disorders.
LixivaptanInvestigated for use/treatment in hyponatremia and congestive heart failure.
AlmorexantInvestigated for use/treatment in sleep disorders and insomnia.
MethenamineA urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.
m-Hydroxyhippuric acidNot Available
PD-0325901PD-0325901 has been used in trials studying the treatment and basic science of Melanoma, Solid Tumour, Solid Tumors, Advanced Cancer, and Breast Neoplasms, among others.
R-95845R-95845 is an inhibitor of HIV-1 reverse transcriptase.
AndarineAndarine is a non-steroidal selective androgen receptor modulator.
PH-797804PH-797804 has been investigated for the treatment of Osteoarthritis.
AzidocillinFor treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including...
SalicylamideSalicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin....
CinitaprideA benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying.
EnzalutamideAn androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer.
EtamivanEtamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States.
LufenuronLufenuron is used in veterinary for the control of flea.
MasitinibMasitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the...
AZD-4877AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.
MosaprideA prokinetic 5-HT4 receptor agonist used to stimulate gastric motility.
PF-06282999Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects).
NavarixinNavarixin has been investigated for the treatment of Asthma.
MomelotinibMomelotinib has been used in trials studying the treatment of Polycythemia Vera, Primary Myelofibrosis, Post-Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis (PMF), among others.
DanusertibDanusertib has been used in trials studying the treatment of Leukemia.
ArhalofenateArhalofenate has been investigated for the treatment of Gout and Hyperuricemia.
DanegaptideDanegaptide has been investigated for the treatment of Focus of Study is STEMI.
MocetinostatMocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.
EntinostatEntinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic...
FlumatinibFlumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic.
SutezolidSutezolid has been used in trials studying the treatment of Tuberculosis.
VistusertibVistusertib is under investigation for the treatment of Advanced Gastric Adenocarcinoma.
TasisulamTasisulam has been used in trials studying the treatment and basic science of Melanoma, Lymphoma, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
AxelopranAxelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.
TecovirimatAn antiviral medication used to treat smallpox.
CE-224535CE-224535 has been used in trials studying the treatment of Osteoarthritis.
SultamicillinA mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria.
FaropenemFaropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
N-6022N6022 has been used in trials studying the treatment of Asthma and Cystic Fibrosis.
GSK-424887Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and Anxiety Disorder.
BalicatibBalicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.
RadiprodilRadiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain.
AZD-5423AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD).
DefactinibDefactinib has been investigated for the treatment of Malignant Pleural Mesothelioma.
DarexabanDarexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
TacedinalineTacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer.
BavisantBavisant has been used in trials studying the basic science and treatment of Alcoholism, Pharmacokinetics, Drug Interactions, Attention Deficit Hyperactivity Disorder, and Attention Deficit Disorders With Hyperactivity.
RadotinibRadotinib is indicated for the treatment of different types of cancer, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other Bcr-Abl tyrosine-kinase inhibitors, such...
LY-2456302Ly2456302 has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence.
TemocillinTemocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.
BetrixabanA Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients.
CI-1040CI-1040 has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Breast Neoplasms, Pancreatic Cancer, and Colorectal Cancer, among others.
AcotiamideAcotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.
BI-671800Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.
MK-0686MK0686 has been used in trials studying the treatment of Osteoarthritis, Pain, Postoperative, and Neuralgia, Postherpetic.
AZD-9056AZD9056 has been used in trials studying the basic science and treatment of Rheumatoid Arthritis.
JNJ-41443532JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2.
LafutidineLafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD).
RelenoprideRelenopride has been used in trials studying the treatment of Chronic Idiopathic Constipation.
DA-6886DA-6886 has been used in trials studying the treatment of Irritable Bowel Syndrome.
RO-4987655RO4987655 has been used in trials studying the treatment of Neoplasms.
GranotapideGranotapide has been used in trials studying the treatment of Type II Diabetes Mellitus.
CEP-37440CEP-37440 has been used in trials studying the treatment of Solid Tumors.
SCYX-7158SCYX-7158 has been used in trials studying the treatment of Trypanosomiasis, Parasitic Diseases, Protozoan Infections, and Trypanosomiasis, African.
4SC-2024SC-202 has been used in trials studying the treatment of Advanced Hematologic Malignancies.
EtofamideEtofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued .
EpicillinNot Annotated
DifenpiramideNot Annotated
Iobenzamic acidNot Annotated
CleboprideA dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy.
ClefamideNot Annotated
PenamecillinNot Annotated
AspoxicillinNot Annotated
MetampicillinMetampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the...
IniparibNot Annotated
BrovanexineNot Annotated
LGD-6972LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus).
TAS-116TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors).
SelonsertibSelonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).
GTX-758GTX-758 is under investigation in clinical trial NCT01420861 (GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer).
LinrodostatLinrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants).
DifamilastDifamilast is under investigation in clinical trial NCT01702181 (A Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermatitis).
FallyprideFallypride is under investigation in clinical trial NCT02310360 (Striatal and Extra-striatal Dopamine Release in Response to Food in Healthy Humans).
OlorofimOlorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects).
SulopenemSulopenem is under investigation in clinical trial NCT03357614 (Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults).
NacubactamNacubactam is under investigation in clinical trial NCT03174795 (A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection).
AcumapimodAcumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers).
TAK-715TAK-715 is under investigation in clinical trial NCT00760864 (Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis).
AcetyldinalineAcetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
ACT-709478ACT-709478 is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).
BelumosudilAn oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD).
DofetilideA class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.
GlimepirideA sulfonylurea drug used to treat type 2 diabetes mellitus.
CefotiamA cephalosporin antibiotic used to treat a variety of bacterial infections.
SulfanilamideA sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
SulfisoxazoleA sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.
CefmenoximeUsed to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria.
CefmetazoleA cephalosporin antibiotic used to treat a variety of bacterial infections.
ArgatrobanA synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
FlucloxacillinA narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA).
ErtapenemA carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms.
IbutilideA class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion.
ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
EthoxzolamideFor use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
SulfadiazineA sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
AcetohexamideUsed in the management of diabetes mellitus type 2 (adult-onset).
StreptozocinA nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma.
CefpiramideFor treatment of severe infections caused by susceptible bacteria such as P. aeruginosa.
LoracarbefUsed to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,...
CefalotinA broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract.
DicloxacillinA penicillin used to treat penicillinase-producing bacterial infections that are susceptible to the drug.
CefotaximeA third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.
MetolazoneA thiazide-like diuretic used to treat hypertension.
ZafirlukastA leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.
BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
CarbenicillinFor the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria.
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
CisaprideA medication used to treat heartburn associated with GERD.
NafcillinA penicillin derivative antibiotic used to treat susceptible staphylococcal infections.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
SulfacetamideA sulfonamide used to treat inflammatory ocular conditions and acne vulgaris.
SulfametopyrazineAn antibiotic used in the treatment or prevention of bacterial infections and malaria.
CefiximeA third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.
ChlorpropamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
CephaloglycinFor treatment of severe infections caused by susceptible bacteria.
AmprenavirA protease inhibitor used to treat HIV infection.
OxacillinA penicillin antibiotic used to treat a number of susceptible bacterial infections.
ZileutonA leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
MeropenemA carbapenem antibiotic used to treat a wide variety of infections in the body.
SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
CefaclorA second generation cephalosporin used to treat a wide variety of infections in the body.
TolazamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
SulfapyridineA sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum.
ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
CeforanideFor the treatment of infections caused by susceptible organisms.
TipranavirA protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.
MezlocillinUsed to treat serious gram–negative infections of the lungs, urinary tract, and skin.
CyclacillinFor the treatment of bacterial infections caused by susceptible organisms.
HydroxyureaAn antimetabolite used to treat sickle cell anemia crisis.
GlyburideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
ProcainamideA medication used to treat life threatening ventricular arrhythmias.
TocainideAn orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias.
AzlocillinFor the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae.
CefditorenA broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
CefuroximeA cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo.
GliclazideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
PhenacemideUsed to control certain seizures in the treatment of epilepsy.
TolbutamideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
CefapirinA first generation cephalosporin indicated in the treatment of susceptible bacterial infections.
CefadroxilA cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis.
DiclofenamideA carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.
CefprozilA cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
ProcarbazineAn antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents.
MoclobemideA monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder.
LomustineAn alkylating agent used as a part of chemotherapeutic regimens for the treatment of primary and metastatic brain tumors as well as refractory or relapsed Hodgkin's disease in addition to surgical and/or radiotherapeutic treatments.
EncainideA voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.
GliquidoneA sulfonylurea drug used in the management of diabetes mellitus type 2.
GlisoxepideFor the treatment of diabetes mellitus type 2.
PractololUsed in the emergency treatment of cardiac arrhythmias.
SulfacytineUsed orally in the treatment of acute urinary tract infections.
SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
FosamprenavirAn antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
QuinethazoneUsed to treat hypertension.
CefamandoleA beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections.
CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
CefonicidFor the treatment of bacterial infections caused by susceptible microorganisms.
CefoperazoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.
CefotetanAn antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections.
CefoxitinA semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection.
CefradineA first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues.
GlymidineGlycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.
BezafibrateA lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder.
CefepimeA fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections.
CefacetrileA broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections.
CeftibutenA third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.
CefpodoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
DiethyltryptamineDiethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
SulfamerazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
SulfamethazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
MeticillinUsed to treat infections caused by susceptible Gram-positive bacteria, particularly beta-lactamase-producing organisms such as Staphylococcus aureus that would otherwise be resistant to most penicillins.
PivampicillinAn ampicillin prodrug used to treat a variety of infections.
SC-74020Not Available
N,N-dimethylformamideNot Available
AR-AO-14418Not Available
WAY-151693Not Available
MozenavirNot Available
S-EthylisothioureaS-Ethylisothiourea is a nitric oxide synthase inhibitor.
GeldanamycinNot Available
N-BenzylformamideNot Available
VorinostatA histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideNot Available
PiretanideA loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin.
DoramapimodDoramapimod is a P38 MAP kinase inhibitor.
N-acetyl-N'-beta-D-glucopyranosyl ureaNot Available
Cephalosporin CNot Available
CyclohexylformamideNot Available
N-phenylthioureaNot Available
PhenacetinUsed principally as an analgesic.
Salicylhydroxamic AcidNot Available
ICI-164384Not Available
UreaA keratolytic emollient used to treat hyperkeratotic lesions and moisturize the skin.
Deacetoxycephalosporin CNot Available
ThiocitrullineNot Available
CoelenteramideNot Available
FotemustineAn alkylating agent used in the treatment of metastatic melanoma.
N-(Benzoylcarbamoyl)-beta-D-glucopyranosylamineNot Available
AminoquinurideNot Available
Paratoulene phosphateNot Available
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideNot Available
LatamoxefLatamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,...
CarboxinA systemic agricultural fungicide and seed treatment agent.
NimesulideA cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea.
CeliprololA beta-blocker for the management of hypertension and angina pectoris.
MerimepodibFor the treatment of hepatitis C virus (HCV) infection.
CeftobiproleA cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria.
BelinostatA histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
EprotiromeInvestigated for use/treatment in hyperlipidemia, metabolic disease, and obesity.
INCB13739Investigated for use/treatment in diabetes mellitus type 2 and diabetes prevention.
SLV319Investigated for use/treatment in obesity.
CimicoxibInvestigated for use/treatment in depression.
AP5280Investigated for use/treatment in solid tumors.
TanespimycinInvestigated for use/treatment in leukemia (myeloid) and solid tumors.
AT9283Investigated for use/treatment in cancer/tumors (unspecified), leukemia (myeloid), and solid tumors.
KD3010Investigated for use/treatment in metabolic disease and obesity.
XL765For the treatment of various forms of cancer.
Silver sulfadiazineA topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.
PimavanserinA second generation atypical antipsychotic used for the treatment of hallucinations and delusions caused by Parkinson's Disease.
Actelion-1Investigated for use/treatment in cardiovascular disorders, hypertension, and pulmonary hypertension.
NCX 701Investigated for use/treatment in pain (acute or chronic).
VX-702Investigated for use/treatment in coronary artery disease, inflammatory disorders (unspecified), and rheumatoid arthritis.
AMG-131Investigated for use/treatment in diabetes mellitus type 2.
AVN-944Investigated for use/treatment in cancer/tumors (unspecified), leukemia (unspecified), lymphoma (unspecified), multiple myeloma, and pancreatic cancer.
NaluzotanInvestigated for use/treatment in anxiety disorders and depression.
RetaspimycinInvestigated for use/treatment in gastric cancer, lung cancer, and multiple myeloma.
ElesclomolInvestigated for use/treatment in melanoma.
CefilavancinInvestigated for use/treatment in bacterial infection, skin infections/disorders, and staph bacterial infections.
LaromustineInvestigated for use/treatment in brain cancer, cancer/tumors (unspecified), colorectal cancer, leukemia (lymphoid), leukemia (myeloid), lung cancer, myelodysplastic syndrome, pediatric indications, and solid tumors.
NS-3728Investigated for use/treatment in anemia (sickle cell) and cancer/tumors (unspecified).
UC-781Investigated for use/treatment in HIV infection.
ResatorvidInvestigated for use/treatment in sepsis and septicemia.
LinifanibInvestigated for use/treatment in leukemia (myeloid), myelodysplastic syndrome, and solid tumors.
VX-148Investigated for use/treatment in autoimmune diseases, psoriasis and psoriatic disorders, and viral infection.
SNS-314Investigated for use/treatment in solid tumors.
SulfathiazoleSulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
SulfadimethoxineFor use in the treatment of infections.
DoripenemAn antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections.
LacosamideAn antiepileptic drug used to treat partial onset seizures in adults.
UdenafilA PDE5 inhibitor used to treat erectile dysfunction.
GlesatinibInvestigated for use/treatment in cancer/tumors (unspecified).
RefametinibInvestigated for use/treatment in cancer/tumors (unspecified).
AR-9281Investigated for use/treatment in hypertension.
ElinogrelInvestigated for use/treatment in cardiovascular disorders and myocardial infarction.
IndisulamInvestigated for use/treatment in lung cancer.
DeclopramideInvestigated for use/treatment in colorectal cancer and inflammatory bowel disease.
TicaloprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
Ceftaroline fosamilAn antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.
Estradiol sulfamateInvestigated for use/treatment in endometriosis.
AxitinibAn oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
ClazosentanInvestigated for use/treatment in strokes.
SulfaphenazoleFor the treatment bacterial infections.
CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
MafenideAn antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.
NiclosamideAn anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.
SulfameterLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
PLX-4720Not Available
TO-901317TO-901317 is an LXRalpha and LXRbeta agonist.
SKF-91488Not Available
NesbuvirNesbuvir has been investigated for the treatment of Hepatitis C.
GW-813893Not Available
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamideNot Available
S-23An androgen receptor modulator.
CGS-27023Not Available
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamideNot Available
H-89Not Available
IDD594Not Available
PlatensimycinNot Available
2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACIDNot Available
4-(2-AMINOETHYL)BENZENESULFONAMIDENot Available
SulfamoxoleFor the treatment of bacterial infection.
MetiamidePotential in the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
VismodegibA hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.
CabozantinibA tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.
VemurafenibA kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
RegorafenibA kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
IndoraminIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
IbuproxamIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
AzosemideAzosemide is a loop diuretic used to treat hypertension, edema, and ascites.
GlibornurideGlibornuride is a sulfonylurea-type anti-diabetic drug.
CefaloridineCephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
BromoprideA substituted benzamide, closely related to metoclopramide, used as an antiemetic.
BlinatumomabAn antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
CefminoxCefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.
LenvatinibA receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
DasabuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
PiracetamA nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer.
CaroxazoneFor the treatment of depression.
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
OmbitasvirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
ParitaprevirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
CarindacillinA penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA.
Procaine benzylpenicillinA local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection.
SulbactamAn beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
OsimertinibA tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
SulfabenzamideA sulfonamide antibacterial used as an ingredient in various topical and vaginal preparations to treat certain infections, but has been discontinued by the FDA.
AllantoinAn ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns.
Carbamide peroxideA medication used to loosen ear wax, whiten teeth, and clean oral wounds.
DiethyltoluamideAn insect repellant, also known as DEET.
NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
CefroxadineWas used for the treatment of bacterial infections.
CefaloniumNot Annotated
ClorsulonNot Annotated
DeracoxibDeracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to...
NicarbazinNot Annotated
SulfachlorpyridazineA sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
SulfaethoxypyridazineNot Annotated
SulfanitranNot Annotated
SulfaquinoxalineSulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K...
ZoaleneDinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.
CeftiofurCeftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active...
CefovecinCefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. It is the first single-dose injectable antibiotic for dogs and cats that assures owner...
ImidocarbImidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.
GrazoprevirAn antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections.
AsunaprevirAn NS3 protease inhibitor used to treat hepatitis C genotype 1b.
NitrocefinNitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin...
RabusertibRabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer.
PictilisibPictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
2-chloroethyl-3-sarcosinamide-1-nitrosourea2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific.
PavinetantPavinetant has been used in trials studying the basic science and treatment of Safety and Schizophrenia.
IlorasertibIlorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Antineoplaston A10Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
EpacadostatEpacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others.
EncorafenibA kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations.
PF-00489791PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic Nephropathies, Hypertension, Pulmonary, and Peripheral Vascular Disease.
VonoprazanA potassium-competitive acid blocker used in the treatment of erosive diseases of the digestive tract, including reflux esophagitis and duodenal ulcers.
SpebrutinibSpebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
PilaralisibPilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors,...
DanoprevirDanoprevir has been used in trials studying the treatment of Hepatitis C, Chronic.
MirodenafilMirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
TivozanibA kinase inhibitor to treat adult patients with renal cell carcinoma (RCC) who have failed prior systemic therapies or experienced relapsed disease.
AZD-5672Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis.
Omecamtiv MecarbilOmecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among others.
BaricitinibA Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist.
TMC-647055TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, and Chronic Hepatitis C Virus.
PF-04958242PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural.
PritelivirPritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
RelugolixAn oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.
LitronesibLitronesib has been used in trials studying the treatment of Solid Tumors, Ovarian Cancer, Gastric Cancer, Prostate Cancer, and Acute Leukaemia, among others.
EtiracetamEtiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
PF-00610355PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.
SB-705498SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
InfigratinibAn FGFR inhibitor used to treat locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) rearrangement.
AvagacestatAvagacestat has been investigated for the basic science and treatment of Alzheimer Disease.
GisadenafilGisadenafil has been investigated for the treatment of Prostatic Hyperplasia.
RociletinibRociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
VaniprevirVaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C...
FlomoxefFlomoxef has been used in trials studying the treatment of Urinary Tract Infection.
AZD-1236AZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
GlasdegibA sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy.
PF-04457845PF-04457845 is under investigation in Fear Conditioning. PF-04457845 has been investigated for the treatment of Tourette Syndrome and Cannabis Dependence.
VoxilaprevirA nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
T-900607T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.
EnobosarmEnobosarm has been used in trials studying the treatment of Stress Urinary Incontinence and Triple Negative Breast Cancer.
FigopitantFigopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers).
ElubrixinElubrixin has been used in trials studying the treatment of Cystic Fibrosis, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease (COPD).
PF-03715455PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive, and Chronic Obstructive Pulmonary Disease (COPD).
PresatovirPresatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections.
VerdinexorKpt 335 is under investigation in clinical trial NCT02431364 (Trial of Safety and Tolerability of Oral Verdinexor (Verdinexor) in Healthy Adults).
LandiololAn ultra short-acting selective beta-blocker used for rapid ventricular rate control in cases of supraventricular tachycardia.
KRN-7000KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients...
IguratimodIguratimod is under investigation in Rheumatoid Arthritis.
AZD-7762AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
ABT-751ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.
BegacestatBegacestat has been used in trials studying the treatment and basic science of Alzheimer Disease.
VidupiprantVidupiprant has been used in trials studying the treatment and basic science of Asthma.
GLPG-0187GLPG0187 has been used in trials studying the treatment of Solid Tumors.
ForetinibForetinib has been used in trials studying the treatment of Cancer, Breast Cancer, Carcinoma, Renal Cell, Recurrent Breast Cancer, and Neoplasms, Head and Neck, among others. Foretinib is an orally...
NavitoclaxNavitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is...
BizelesinBizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
NetazepideNetazepide has been used in trials studying the prevention and treatment of Dyspepsia, Hypergastrinaemia, Barrett's Esophagus, ECL-cell Hyperplasia, and Rebound Hyperacidity, among others.
ApricoxibApricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others.
ResminostatResminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others.
PolmacoxibPolmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee.
VoxtalisibVoxtalisib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Breast Cancer, among others.
PAC-14028PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea.
IoforminolIoforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH With or Without PCI.
AlvespimycinInvestigated for use as an antineoplastic agent for solid tumors, advanced solid tumours or acute myeloid leukaemia.
E-7820E7820 has been investigated for the treatment of Colon Cancer and Rectal Cancer.
Iofolastat I-123Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).
RacloprideRaclopride has been used in trials studying Parkinson Disease.
SparsentanSparsentan has been used in trials studying the treatment of Focal Segmental Glomerulosclerosis. Sparsentan is the first and only dual-acting angiotensin and endothelin receptor antagonist (DARA) in development.
NelotanserinNelotanserin has been used in trials studying the treatment of Lewy Body Dementia, Visual Hallucinations, Dementia With Lewy Bodies, and REM Sleep Behavior Disorder. It is a highly selective antagonist...
LY-295501ILX-295501 has been used in trials studying the treatment of Ovarian Cancer, Metastatic Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cavity Cancer.
PiperineBioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
RazupenemRazupenem has been used in trials studying the treatment of Skin Infections.
ReparixinReparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type 1, and Pancreatic...
TaprenepagTaprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
IbipinabantIbipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
K-134K-134 has been used in trials studying the treatment of Intermittent Claudication.
OmipalisibOmipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis.
PilsicainidePilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
MibampatorMibampator has been used in trials studying the treatment of Alzheimer's Disease.
DaporinadDaporinad has been used in trials studying the treatment of Melanoma, Cutaneous T-cell Lymphoma, and B-cell Chronic Lymphocytic Leukemia.
AmuvatinibAmuvatinib is a selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3. Amuvatinib also suppresses Rad51 protein, a critical component of...
CGI-1842JI-101 has been used in trials studying the treatment of Cancer, Colon Cancer, Neuroendocrine, Ovarian Cancer, and Advanced Solid Tumors.
AtreleutonAtreleuton has been used in trials studying the treatment of Atherosclerosis and Coronary Artery Disease.
CHF-6001CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease.
AtaciguatAtaciguat has been investigated for the basic science of Aortic Valve Stenosis.
SivelestatSivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
QuizartinibQuizartinib is under investigation in Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies. It is a potent inhibitor of FLT3.
ChlorsulfaquinoxalineChlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer.
CP-547632CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others.
DONUDonu has been used in trials studying the treatment of Psychosis.
IPI-493IPI-493 has been used in trials studying the treatment of Advanced Malignancies.
BiapenemA carbapenem antibiotic indicated in the treatment of bacterial infections.
RamatrobanRamatroban has been used in trials studying the treatment of Asthma.
CH-5132799CH5132799 has been used in trials studying the treatment of Solid Tumors.
UpamostatUpamostat has been used in trials studying the treatment of Pancreatic Cancer.
ACT-451840ACT-451840 has been used in trials studying Malaria.
NimustineNimustine has been used in trials studying the treatment of Glioblastoma.
GDC-0349GDC-0349 has been used in trials studying the treatment of Non-Hodgkin's Lymphoma, Solid Tumor.
PKI-179PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors.
Inosine pranobexA medication used to treat subacute sclerosing panencephalitis.
RipasudilA rho kinase inhibitor indicated to treat ocular hypertension and open-angle glaucoma.
ApronalideApronalide is approved in Japan. Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura .
PhthalylsulfathiazoleA sulfonamide antibacterial indicated in the treatment of gastrointestinal infections.
PenimepicyclinePenimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification...
CefatrizineNot Annotated
SultoprideSultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics .
SulfaisodimidineSulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has...
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
PheneturideNot Annotated
BromisovalNot Annotated
MefrusideNot Annotated
CarbutamideNot Annotated
CefodizimeA broad-spectrum, third-generation cephalosporin used to treat serious infections caused by susceptible bacteria.
CefsulodinNot Annotated
CefetametNot Annotated
CarfecillinNot Annotated
MebicarNot Annotated
VeraliprideNot Annotated
EthenzamideNot Annotated
SulfatolamideNot Annotated
CarumonamNot Annotated
SuccinylsulfathiazoleNot Annotated
Carbaspirin calciumAn NSAID indicated in the treatment of short term pain and fever.
ClorexoloneNot Annotated
CefbuperazoneNot Annotated
SemustineNot Annotated
LorcainideNot Annotated
BenorilateNot Annotated
PropicillinNot Annotated
CefozopranNot Annotated
MetahexamideNot Annotated
CefpiromeAn antibiotic indicated in the treatment of a wide variety of infections in the body.
SulbenicillinNot Annotated
SulfathioureaNot Annotated
SulfaguanidineNot Annotated
EpanololEpanolol is an beta blocker.
SulfamethoxypyridazineA sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis.
CefazedoneNot Annotated
ClopamideClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
XipamideA diuretic indicated in the treatment of edema.
TalampicillinNot Annotated
CarbromalNot Annotated
CeftezoleNot Annotated
RanimustineNot Annotated
NoxytiolinLocal antibacterial that probably acts by releasing formaldehyde in aqueous solutions. It is used for THERAPEUTIC IRRIGATION of infected body cavities - bladder, peritoneum, etc. and as a spray for...
GlecaprevirA Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
SB-269970SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist...
Acetyl sulfisoxazoleAcute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the...
SC-236SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
NS-398NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.
ImidureaImidurea is an antimicrobial preservative used in cosmetics. It acts as a formaldehyde releaser.
7-Aminodesacetoxycephalosporanic acidNot Annotated
DiazolidinylureaAn ingredient used in hospitals for disinfection.
Ceramide APNot Annotated
Ceramide NGNot Annotated
Cefamandole nafateA second generation cephalosporin indicated in the prevention of infections during surgery.
MebenilAn obsolete fungicide used to control various pathogens on cereals and seed potatoes.
Ceftobiprole medocarilA cephalosporin indicated in the treatment of pneumonia.
NarlaprevirNot Annotated
LanifibranorLanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337).
Piflufolastat F 18A radiopharmaceutical diagnostic agent used with PET to image PSMA-positive lesions for the diagnosis of metastatic or recurrent prostate cancer.
RipretinibA kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST).
PF-05089771PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee).
CeralasertibCeralasertib is under investigation in clinical trial NCT03682289 (Phase II Trial of AZD6738 Alone and in Combination With Olaparib).
ElsulfavirineElsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact...
BMS-817399BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).
AbrocitinibA kinase inhibitor used to treat moderate-to-severe atopic dermatitis in adults.
PyrotinibPyrotinib is under investigation in clinical trial NCT03756064 (Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer).
FlufenoxuronFlufenoxuron is under investigation in clinical trial NCT00922870 (Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock).
EdasalonexentEdasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes).
TAK-243TAK-243 is under investigation in clinical trial NCT03816319 (TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia).
ApararenoneApararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995).
SitravatinibSitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma).
ABT-639ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain).
AprocitentanAprocitentan is under investigation in clinical trial NCT03541174 (A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and...
AgerafenibAgerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).
GefapixantGefapixant is under investigation in clinical trial NCT02397460 (Effect of Gefapixant (AF-219/MK-7264) on Cough Reflex Sensitivity).
SurufatinibSurufatinib is under investigation in clinical trial NCT02588170 (Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors).
Tipranavir C-14Tipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects).
ABT-072ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat...
DubermatinibDubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
BirabresibBirabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).
RSV-604RSV-604 is under investigation in clinical trial NCT00416442 (Safety, Tolerability and Pharmacokinetic Study of Single and Multiple Intravenous Doses of RSV604 in Healthy Subjects.).
JNJ-26489112JNJ-26489112 is under investigation in clinical trial NCT00579384 (A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy).
TelaglenastatTelaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors).
VercirnonVercirnon is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. It is...
FlorasulamFlorasulam is under investigation in clinical trial NCT01193465 (Temperature and Humidity Among Different Anesthesia Work-station).
VM4-037VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).
TefinostatTefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)).
SAR-125844SAR-125844 is under investigation in clinical trial NCT01391533 (Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors).
DihydrocapsiateDihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate).
GiripladibGiripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee).
Iodohippuric acidIodohippuric acid is under investigation in clinical trial NCT02599844 (Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults).
FluazuronFluazuron is a benzoyl phenylurea compound.
TMC-310911TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections....
FasitibantFasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).
Sulbactam pivoxilA prodrug of a beta-lactamase inhibitor used to improve the efficacy of beta lactam antibiotics
SulfametroleAn antibiotic indicated in combination intravenous products for various bacterial infections.
Salicylamide O-acetic acidA salicylate indicated in combination with local anesthetics and corticosteroids for short term treatment of inflammation.
Levosulpirideindicated to treat dyspepsia, symptoms of Meniere's syndrome, and second line in the treatment of drug-induced nausea and vomiting.
PLX8394PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors).
APG-1387APG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B).
BatabulinBatabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients).
LadarixinLadarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function).
MethfuroxamMethfuroxam is under investigation in clinical trial NCT01213407 (Dendritic Cell Cancer Vaccine for High-grade Glioma).
NevanimibeNevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).
PexmetinibPexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab or Ipilimumab).
GSK-2981278GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis).
ABX-196ABX-196 is under investigation in clinical trial NCT03897543 (ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma).
AlmonertinibAlmonertinib is a third-generation EGFR tyrosine kinase inhibitor targeting EGFR-sensitizing and T790M resistance mutations.[A231859, A231864, A231869] It is being investigated against advanced or metastatic EGFR-mutated non-small cell lung cancer (NSCLC).
FasentinNot Annotated
Drugs & Drug Targets
DrugTargetType
LidocaineSodium channel protein type 5 subunit alphatarget
LidocaineSodium channel protein type 10 subunit alphatarget
LidocaineEpidermal growth factor receptortarget
LidocaineSodium channel protein type 9 subunit alphatarget
LidocaineCytochrome P450 1A2enzyme
LidocaineCytochrome P450 2D6enzyme
LidocaineCytochrome P450 3A4enzyme
LidocaineCytochrome P450 3A5enzyme
LidocaineCytochrome P450 3A7enzyme
LidocaineSolute carrier family 22 member 5transporter
LidocaineP-glycoprotein 1transporter
LidocaineCytochrome P450 2A6enzyme
LidocaineCytochrome P450 2B6enzyme
LidocaineCytochrome P450 2C8enzyme
LidocaineCytochrome P450 2C9enzyme
LidocaineSodium channel protein type 4 subunit alphatarget
LidocaineAlpha-1-acid glycoprotein 1target
LidocaineAlpha-1-acid glycoprotein 2target
BupivacaineSodium channel protein type 10 subunit alphatarget
BupivacaineProstaglandin E2 receptor EP1 subtypetarget
BupivacaineCytochrome P450 3A4enzyme
BupivacaineCytochrome P450 2C19enzyme
BupivacaineCytochrome P450 2D6enzyme
PrilocaineSodium channel protein type 5 subunit alphatarget
LevobupivacaineSodium channel protein type 10 subunit alphatarget
LevobupivacaineCytochrome P450 3A4enzyme
LevobupivacaineCytochrome P450 1A2enzyme
OseltamivirNeuraminidasetarget
OseltamivirSialidase-1target
OseltamivirSialidase-2target
OseltamivirMultidrug resistance-associated protein 4transporter
OseltamivirSolute carrier family 15 member 1transporter
OseltamivirSolute carrier family 22 member 8transporter
OseltamivirLiver carboxylesterase 1enzyme
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilMultidrug resistance-associated protein 4transporter
SildenafilMultidrug resistance-associated protein 5transporter
SildenafilMultidrug resistance-associated protein 7transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilP-glycoprotein 1transporter
SildenafilOrnithine decarboxylasetarget
SildenafilProgrammed cell death 1 ligand 1target
AcetaminophenProstaglandin G/H synthase 1target
AcetaminophenProstaglandin G/H synthase 2target
AcetaminophenCytochrome P450 1A2enzyme
AcetaminophenCytochrome P450 2E1enzyme
AcetaminophenP-glycoprotein 1transporter
AcetaminophenCytochrome P450 2D6enzyme
AcetaminophenCytochrome P450 2A6enzyme
AcetaminophenCytochrome P450 3A4enzyme
AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
AcetaminophenSulfotransferase 1A1enzyme
AcetaminophenSulfotransferase 1A3/1A4enzyme
AcetaminophenArylamine N-acetyltransferase 2enzyme
AcetaminophenProstaglandin E synthase 3target
AcetaminophenTransient receptor potential cation channel subfamily V member 1target
AcetaminophenSerum albumincarrier
AcetaminophenFatty-acid amide hydrolase 1enzyme
AcetaminophenGlutathione S-transferase Penzyme
AcetaminophenGlutathione S-transferase Mu 1enzyme
AztreonamPenicillin-binding protein 3target
AztreonamBeta-lactamasetarget
SulpirideDopamine D2 receptortarget
SulpirideDopamine D3 receptortarget
SulpirideCholinesteraseenzyme
SulpirideCarbonic anhydrase 2target
SulpirideCarbonic anhydrase 3target
SulpirideSerum albumincarrier
SulpirideSolute carrier family 22 member 1transporter
SulpirideSolute carrier family 22 member 2transporter
SulpirideMultidrug and toxin extrusion protein 1transporter
SulpirideMultidrug and toxin extrusion protein 2transporter
SulpirideDopamine D4 receptortarget
SulpirideSolute carrier family 22 member 3transporter
SulpirideP-glycoprotein 1transporter
SulpirideATP-binding cassette sub-family G member 2transporter
RemoxiprideDopamine D2 receptortarget
RemoxiprideDopamine D4 receptortarget
Remoxipride5-hydroxytryptamine receptor 2Atarget
RemoxiprideSigma non-opioid intracellular receptor 1target
RemoxiprideDopamine D3 receptortarget
RemoxiprideCytochrome P450 2D6enzyme
Remoxipridealpha1-acid glycoproteincarrier
RemoxiprideCytochrome P450 1A2enzyme
RemoxiprideCytochrome P450 2B1enzyme
RemoxiprideCytochrome P450 3A Subfamilyenzyme
AmpicillinSerum albumincarrier
AmpicillinSolute carrier family 22 member 5transporter
AmpicillinSolute carrier family 15 member 1transporter
AmpicillinSolute carrier family 15 member 2transporter
AmpicillinPenicillin-binding protein 2atarget
AmpicillinPenicillin-binding protein 1btarget
AmpicillinPenicillin-binding protein 3target
AmpicillinPenicillin-binding protein 1Atarget
AmpicillinPenicillin-binding protein 2Btarget
AmpicillinMonocarboxylate transporter 1transporter
AmpicillinSolute carrier family 15 member 1target
AmpicillinSolute carrier family 15 member 2target
AmpicillinAngiopoietin-1 receptortarget
PhenoxymethylpenicillinPenicillin-binding protein 1Atarget
PhenoxymethylpenicillinMecA PBP2' (penicillin binding protein 2')target
PhenoxymethylpenicillinD-alanyl-D-alanine carboxypeptidase DacBtarget
PhenoxymethylpenicillinPenicillin acylasetarget
PhenoxymethylpenicillinSolute carrier family 15 member 1target
CeftazidimeSolute carrier family 22 member 6transporter
CeftazidimePeptidoglycan synthase FtsItarget
CeftazidimePenicillin-binding protein 1Atarget
CeftazidimePenicillin-binding protein 1Btarget
CeftazidimePenicillin-binding protein 2target
CeftazidimeSerum albumincarrier
CelecoxibProstaglandin G/H synthase 2target
Celecoxib3-phosphoinositide-dependent protein kinase 1target
CelecoxibCytochrome P450 2C9enzyme
CelecoxibCytochrome P450 2D6enzyme
CelecoxibMultidrug resistance-associated protein 4transporter
CelecoxibCytochrome P450 3A4enzyme
CelecoxibCytochrome P450 2C8enzyme
CelecoxibCarbonic anhydrase 2target
CelecoxibCarbonic anhydrase 3target
CelecoxibBile salt export pumptransporter
CelecoxibCadherin-11target
CelecoxibP-glycoprotein 1transporter
CelecoxibATP-binding cassette sub-family G member 2transporter
CelecoxibProstaglandin G/H synthase 2enzyme
CelecoxibSialidase-1target
FlutamideAndrogen receptortarget
FlutamideCytochrome P450 1A2enzyme
FlutamideCytochrome P450 3A4enzyme
FlutamideCytochrome P450 1A1enzyme
FlutamideCytochrome P450 1B1enzyme
FlutamideCytochrome P450 3A5enzyme
FlutamideAryl hydrocarbon receptortarget
FlutamideNuclear receptor subfamily 1 group I member 2target
CinchocaineSodium channel protein type 5 subunit alphatarget
CinchocaineSodium channel protein type 10 subunit alphatarget
CinchocaineCalmodulintarget
CinchocaineCholinesteraseenzyme
CephalexinSerum albumincarrier
CephalexinSolute carrier family 22 member 5transporter
CephalexinSolute carrier family 15 member 1transporter
CephalexinSolute carrier family 15 member 2transporter
CephalexinSolute carrier family 22 member 6transporter
CephalexinSolute carrier family 22 member 8transporter
CephalexinMultidrug and toxin extrusion protein 1transporter
CephalexinPenicillin-binding protein 3target
CephalexinPenicillin-binding protein 2atarget
CephalexinPenicillin-binding protein 1btarget
CephalexinPenicillin-binding protein 1Atarget
CephalexinPenicillin-binding protein 2Btarget
SulfamethizoleDihydropteroate synthasetarget
SulfamethizoleSerum albumincarrier
SulfamethizoleCytochrome P450 2C9enzyme
LabetalolAlpha-1 adrenergic receptorstarget
LabetalolBeta-1 adrenergic receptortarget
LabetalolBeta-2 adrenergic receptortarget
LabetalolCytochrome P450 2D6enzyme
LabetalolCytochrome P450 2C19enzyme
LabetalolSerum albumincarrier
Labetalolalpha1-acid glycoproteincarrier
LabetalolATP-binding cassette sub-family B member 5transporter
LabetalolUDP-glucuronosyltransferase 1-1enzyme
LabetalolUDP-glucuronosyltransferase 2B7enzyme
LabetalolUDP-glucuronosyltransferase 1-9enzyme
Linezolid23S ribosomal RNAtarget
LinezolidAmine oxidase [flavin-containing] Aenzyme
LinezolidAmine oxidase [flavin-containing] Benzyme
LinezolidSerum albumincarrier
LinezolidSolute carrier family 22 member 6transporter
LinezolidSolute carrier family 22 member 8transporter
Sumatriptan5-hydroxytryptamine receptor 1Dtarget
Sumatriptan5-hydroxytryptamine receptor 1Btarget
Sumatriptan5-hydroxytryptamine receptor 1Ftarget
SumatriptanAmine oxidase [flavin-containing] Aenzyme
Sumatriptan5-hydroxytryptamine receptor 1Atarget
SumatriptanSolute carrier organic anion transporter family member 1A2transporter
SumatriptanP-glycoprotein 1transporter
SumatriptanATP-binding cassette sub-family G member 2transporter
SumatriptanSolute carrier organic anion transporter family member 1B1transporter
FurosemideSolute carrier family 12 member 1target
FurosemideSerum albumincarrier
FurosemideSolute carrier family 22 member 6transporter
FurosemideSolute carrier family 22 member 5transporter
FurosemideSolute carrier family 22 member 8transporter
FurosemideCanalicular multispecific organic anion transporter 1transporter
FurosemideSolute carrier organic anion transporter family member 2A1transporter
FurosemideSolute carrier family 22 member 11transporter
Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
FurosemideCarbonic anhydrase 2target
FurosemideUDP-glucuronosyltransferase 1-1enzyme
FurosemideThyroxine-binding globulincarrier
FurosemideG-protein coupled receptor 35target
TamsulosinAlpha-1A adrenergic receptortarget
TamsulosinAlpha-1D adrenergic receptortarget
TamsulosinAlpha-1B adrenergic receptortarget
TamsulosinAlpha-1-acid glycoprotein 1carrier
TamsulosinCytochrome P450 2D6enzyme
TamsulosinCytochrome P450 3A4enzyme
HydroflumethiazideSolute carrier family 12 member 1target
HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 4target
HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 2target
HydroflumethiazideCarbonic anhydrase 1target
HydroflumethiazideCarbonic anhydrase 9target
HydroflumethiazideCarbonic anhydrase 12target
HydroflumethiazideSerum albumincarrier
HydroflumethiazideSolute carrier family 22 member 6transporter
HydroflumethiazideSolute carrier family 22 member 8transporter
HydroflumethiazideCarbonic anhydrase 7target
IndapamideCytochrome P450 3A4enzyme
IndapamideSolute carrier family 12 member 3target
IndapamideEpoxide hydrolase 1enzyme
Indapamidealpha1-acid glycoproteincarrier
IndapamideSerum albumincarrier
IndapamideErythrocytecarrier
DorzolamideCarbonic anhydrase 2target
DorzolamideCarbonic anhydrase 1target
DorzolamideCarbonic anhydrase 4target
DorzolamideCytochrome P450 2C9enzyme
DorzolamideCarbonic anhydrase 3target
DorzolamideCytochrome P450 2B1enzyme
DorzolamideCytochrome P450 2E1enzyme
DorzolamideCytochrome P450 3A2enzyme
BimatoprostProstaglandin F2-alpha receptortarget
BimatoprostProstaglandin E2 receptor EP1 subtypetarget
BimatoprostProstaglandin E2 receptor EP3 subtypetarget
BimatoprostCytochrome P450 3A4enzyme
BimatoprostCytochrome P450 3A5enzyme
HydrochlorothiazideSolute carrier family 12 member 3target
HydrochlorothiazideSolute carrier family 22 member 6transporter
HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
HydrochlorothiazideSerum albumincarrier
HydrochlorothiazideSolute carrier family 22 member 11transporter
HydrochlorothiazideMultidrug resistance-associated protein 4transporter
HydrochlorothiazideSolute carrier family 22 member 8transporter
Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 3target
Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 2target
Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 1target
CeruleninFatty acid synthasetarget
RifampicinDNA-directed RNA polymerase subunit betatarget
RifampicinNuclear receptor subfamily 1 group I member 2target
RifampicinCytochrome P450 3A4enzyme
RifampicinCytochrome P450 1A2enzyme
RifampicinCytochrome P450 2C8enzyme
RifampicinUDP-glucuronosyltransferase 1-1enzyme
RifampicinCytochrome P450 2C9enzyme
RifampicinCytochrome P450 2B6enzyme
RifampicinCytochrome P450 2C19enzyme
RifampicinCanalicular multispecific organic anion transporter 2transporter
RifampicinMultidrug resistance-associated protein 5transporter
RifampicinP-glycoprotein 1transporter
RifampicinCanalicular multispecific organic anion transporter 1transporter
RifampicinSolute carrier organic anion transporter family member 2B1transporter
RifampicinBile salt export pumptransporter
RifampicinMultidrug resistance-associated protein 1transporter
RifampicinSolute carrier organic anion transporter family member 1A2transporter
RifampicinSolute carrier organic anion transporter family member 1B3transporter
RifampicinSolute carrier family 22 member 7transporter
RifampicinSolute carrier organic anion transporter family member 1B1transporter
RifampicinCytochrome P450 2A6enzyme
RifampicinCytochrome P450 2E1enzyme
RifampicinCytochrome P450 3A43enzyme
RifampicinCytochrome P450 3A7enzyme
RifampicinSolute carrier family 22 member 6transporter
RifampicinSolute carrier family 22 member 8transporter
RifampicinUDP-glucuronosyltransferase 1-9enzyme
RifampicinCytochrome P450 3A5enzyme
RifampicinSerum albumincarrier
Rifampicinalpha1-acid glycoproteincarrier
BenzylpenicillinSolute carrier family 22 member 5transporter
BenzylpenicillinSolute carrier family 15 member 1transporter
BenzylpenicillinSolute carrier family 15 member 2transporter
BenzylpenicillinSolute carrier family 22 member 6transporter
BenzylpenicillinSolute carrier family 22 member 8transporter
BenzylpenicillinSolute carrier family 22 member 4transporter
BenzylpenicillinSolute carrier family 22 member 11transporter
BenzylpenicillinSolute carrier organic anion transporter family member 2B1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 4A1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 3A1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 1B1transporter
BenzylpenicillinPenicillin-binding protein 3target
BenzylpenicillinSolute carrier family 22 member 8target
BenzylpenicillinSolute carrier family 15 member 1target
BenzylpenicillinSolute carrier family 15 member 2target
BenzylpenicillinBeta-lactamase TEMenzyme
BenzylpenicillinSerum albumincarrier
AmoxicillinSolute carrier family 15 member 1transporter
AmoxicillinSolute carrier family 15 member 2transporter
AmoxicillinSolute carrier family 22 member 6transporter
AmoxicillinCytochrome P450 2C8enzyme
AmoxicillinSerum albumincarrier
AmoxicillinBeta-lactamase 2enzyme
AmoxicillinPenicillin binding proteintarget
BicalutamideAndrogen receptortarget
BicalutamideCytochrome P450 3A4enzyme
BicalutamideCytochrome P450 2C19enzyme
BicalutamideCytochrome P450 2C9enzyme
BicalutamideCytochrome P450 2D6enzyme
BicalutamideP-glycoprotein 1transporter
CloxacillinSerum albumincarrier
CloxacillinSolute carrier family 15 member 1transporter
CloxacillinSolute carrier family 15 member 2transporter
CloxacillinD-alanyl-D-alanine carboxypeptidase DacAtarget
CloxacillinSolute carrier family 22 member 8transporter
CloxacillinPenicillin-binding protein 2Xtarget
CloxacillinPenicillin-binding protein 1Atarget
BrinzolamideCarbonic anhydrase 1target
BrinzolamideCarbonic anhydrase 2target
BrinzolamideCytochrome P450 3A4enzyme
BrinzolamideCarbonic anhydrase 5A, mitochondrialtarget
BrinzolamideCarbonic anhydrase 4target
BrinzolamideCarbonic anhydrase 3target
LevetiracetamSynaptic vesicle glycoprotein 2Atarget
LevetiracetamP-glycoprotein 1transporter
LevetiracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
CeftriaxoneSerum albumincarrier
CeftriaxoneSolute carrier family 15 member 1transporter
CeftriaxoneSolute carrier family 15 member 2transporter
CeftriaxoneSolute carrier family 22 member 6transporter
CeftriaxoneSolute carrier family 22 member 8transporter
CeftriaxoneSolute carrier family 22 member 11transporter
CeftriaxonePenicillin-binding protein 2Btarget
CeftriaxoneGlutamine synthetaseenzyme
CeftriaxoneSolute carrier family 22 member 11target
CeftriaxoneSolute carrier family 22 member 6target
CeftriaxoneSolute carrier family 22 member 8target
CeftriaxoneSolute carrier family 15 member 1target
CeftriaxoneP-glycoprotein 1transporter
MetoclopramideMuscarinic acetylcholine receptor M1target
MetoclopramideDopamine D2 receptortarget
MetoclopramideCytochrome P450 2D6enzyme
Metoclopramide5-hydroxytryptamine receptor 4target
Metoclopramide5-hydroxytryptamine receptor 3Atarget
MetoclopramideCytochrome P450 3A4enzyme
MetoclopramideCytochrome P450 1A2enzyme
MetoclopramideP-glycoprotein 1transporter
MetoclopramideAlpha-1-acid glycoprotein 1carrier
DarunavirHuman immunodeficiency virus type 1 proteasetarget
DarunavirCytochrome P450 3A4enzyme
DarunavirSolute carrier organic anion transporter family member 1B1transporter
DarunavirP-glycoprotein 1transporter
DarunavirSerum albumincarrier
DarunavirAlpha-1-acid glycoprotein 1carrier
DarunavirCytochrome P450 2D6enzyme
PolythiazideSolute carrier family 12 member 3target
PolythiazideSolute carrier family 22 member 6transporter
PolythiazideSolute carrier family 22 member 8transporter
PolythiazideSerum albumincarrier
CeftizoximeSolute carrier family 15 member 1transporter
CeftizoximePenicillin-binding protein 1Atarget
CeftizoximePenicillin-binding protein 1Btarget
CeftizoximeSolute carrier family 22 member 6transporter
CeftizoximeSolute carrier family 22 member 8transporter
CeftizoximePeptidoglycan transpeptidasetarget
CeftizoximeD-alanyl-D-alanine carboxypeptidase DacCtarget
ImipenemPenicillin-binding protein 1Atarget
ImipenemPenicillin-binding protein 1Btarget
ImipenemPenicillin-binding protein 2target
ImipenemPenicillin-binding protein 3target
ImipenemDipeptidase 1enzyme
ImipenemPenicillin-binding protein 4target
ImipenemBeta-lactamase SHV-1enzyme
ImipenemBeta-lactamase TEMenzyme
ImipenemBeta-lactamase CTX-Menzyme
ImipenemBeta-lactamase (KPC-2)enzyme
TazobactamBeta-lactamase TEMtarget
TazobactamSolute carrier family 22 member 6transporter
TazobactamSolute carrier family 22 member 8transporter
TazobactamBeta-lactamase Ohio-1target
TazobactamBeta-lactamase SHV-1target
TicarcillinPenicillin binding protein 2atarget
TirbanibulinProto-oncogene tyrosine-protein kinase Srctarget
TirbanibulinTubulin beta chaintarget
TirbanibulinCytochrome P450 3A4enzyme
TirbanibulinCytochrome P450 2C8enzyme
TirbanibulinCytochrome P450 1A2enzyme
TirbanibulinCytochrome P450 2B6enzyme
TirbanibulinCytochrome P450 2C9enzyme
TirbanibulinCytochrome P450 2C19enzyme
TirbanibulinCytochrome P450 2D6enzyme
TirbanibulinMultidrug and toxin extrusion protein 1transporter
TirbanibulinMultidrug and toxin extrusion protein 2transporter
TirbanibulinSolute carrier organic anion transporter family member 1B1transporter
TirbanibulinSolute carrier organic anion transporter family member 1B3transporter
TirbanibulinSolute carrier family 22 member 1transporter
TirbanibulinSolute carrier family 22 member 2transporter
AmisulprideDopamine D2 receptortarget
AmisulprideDopamine D3 receptortarget
Amisulpride5-hydroxytryptamine receptor 7target
Amisulpride5-hydroxytryptamine receptor 2Atarget
AmisulprideErythrocytecarrier
AmisulprideMultidrug and toxin extrusion protein 1transporter
AmisulprideMultidrug and toxin extrusion protein 2transporter
AmisulprideP-glycoprotein 1transporter
AmisulprideATP-binding cassette sub-family G member 2transporter
AmisulprideSolute carrier family 22 member 1transporter
AmisulprideMu-type opioid receptortarget
AmisulprideDelta-type opioid receptortarget
AmisulprideKappa-type opioid receptortarget
PazopanibVascular endothelial growth factor receptor 1target
PazopanibVascular endothelial growth factor receptor 2target
PazopanibVascular endothelial growth factor receptor 3target
PazopanibPlatelet-derived growth factor receptor alphatarget
PazopanibPlatelet-derived growth factor receptor betatarget
PazopanibMast/stem cell growth factor receptor Kittarget
PazopanibCytochrome P450 3A4enzyme
PazopanibCytochrome P450 2D6enzyme
PazopanibCytochrome P450 2C8enzyme
PazopanibCytochrome P450 1A2enzyme
PazopanibP-glycoprotein 1transporter
PazopanibATP-binding cassette sub-family G member 2transporter
PazopanibSolute carrier organic anion transporter family member 1B1transporter
PazopanibUDP-glucuronosyltransferase 1-1transporter
PazopanibFibroblast growth factor receptor 3target
PazopanibTyrosine-protein kinase ITK/TSKtarget
PazopanibFibroblast growth factor 1target
PazopanibSH2B adapter protein 3target
NepafenacProstaglandin G/H synthase 1target
NepafenacProstaglandin G/H synthase 2target
MirabegronCytochrome P450 3A4enzyme
MirabegronCytochrome P450 2D6enzyme
MirabegronP-glycoprotein 1transporter
MirabegronSolute carrier organic anion transporter family member 1A2transporter
MirabegronSerum albumincarrier
MirabegronAlpha-1-acid glycoprotein 1carrier
MirabegronCholinesteraseenzyme
MirabegronBeta-3 adrenergic receptortarget
MirabegronUDP-glucuronosyltransferase 2B7enzyme
MirabegronUDP-glucuronosyltransferase 1-3enzyme
MirabegronUDP-glucuronosyltransferase 1-8enzyme
MirabegronSolute carrier family 22 member 1transporter
MirabegronSolute carrier family 22 member 2transporter
MirabegronSolute carrier family 22 member 3transporter
MirabegronBeta-1 adrenergic receptortarget
MacitentanCytochrome P450 3A4enzyme
MacitentanCytochrome P450 2C19enzyme
MacitentanEndothelin-1 receptortarget
MacitentanEndothelin B receptortarget
MacitentanSerum albumincarrier
MacitentanCytochrome P450 2C9enzyme
MacitentanCytochrome P450 2C8enzyme
Macitentanalpha1-acid glycoproteincarrier
CeftolozanePenicillin-binding protein 1Btarget
CeftolozanePenicillin-binding protein 3target
CeftolozanePenicillin-binding proteintarget
CeftolozanePenicillin-binding protein 1Ctarget
CeftolozanePenicillin-binding protein 2target
TriclocarbanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
TriclocarbanCytochrome P450 1A1enzyme
TriclocarbanCytochrome P450 1B1enzyme
SelexipagProstacyclin receptortarget
SelexipagLiver carboxylesterase 1enzyme
SelexipagCytochrome P450 2C8enzyme
SelexipagCytochrome P450 3A4enzyme
SelexipagSolute carrier organic anion transporter family member 1B1transporter
SelexipagSolute carrier organic anion transporter family member 1B3transporter
SelexipagP-glycoprotein 1transporter
VenetoclaxApoptosis regulator Bcl-2target
VenetoclaxCytochrome P450 3A4enzyme
VenetoclaxP-glycoprotein 1transporter
VenetoclaxATP-binding cassette sub-family G member 2transporter
VenetoclaxSolute carrier organic anion transporter family member 1B1transporter
AcalabrutinibTyrosine-protein kinase BTKtarget
AcalabrutinibCytochrome P450 3A4enzyme
AcalabrutinibCytochrome P450 3A5enzyme
AcalabrutinibCytochrome P450 3A Subfamilyenzyme
AcalabrutinibSerum albumincarrier
Acalabrutinibalpha1-acid glycoproteincarrier
Lasmiditan5-hydroxytryptamine receptor 1Ftarget
LasmiditanP-glycoprotein 1transporter
LasmiditanATP-binding cassette sub-family G member 2transporter
LasmiditanSolute carrier family 22 member 1transporter
LasmiditanMultidrug and toxin extrusion protein 1transporter
LasmiditanMultidrug and toxin extrusion protein 2transporter
LasmiditanCytochrome P450 2D6enzyme
RevefenacinCytochrome P450 2D6enzyme
RevefenacinMuscarinic acetylcholine receptortarget
RevefenacinSerum albumincarrier
RevefenacinSolute carrier organic anion transporter family member 1B1transporter
RevefenacinSolute carrier organic anion transporter family member 1B3transporter
RevefenacinP-glycoprotein 1transporter
RevefenacinATP-binding cassette sub-family G member 2transporter
EntrectinibCytochrome P450 3A4enzyme
EntrectinibP-glycoprotein 1transporter
EntrectinibHigh affinity nerve growth factor receptortarget
EntrectinibBDNF/NT-3 growth factors receptortarget
EntrectinibNT-3 growth factor receptortarget
EntrectinibProto-oncogene tyrosine-protein kinase ROStarget
EntrectinibTyrosine-protein kinase JAK2target
EntrectinibActivated CDC42 kinase 1target
LorlatinibALK tyrosine kinase receptortarget
LorlatinibCytochrome P450 3A Subfamilyenzyme
LorlatinibCytochrome P450 3A5enzyme
LorlatinibCytochrome P450 2B6enzyme
LorlatinibCytochrome P450 2C8enzyme
LorlatinibCytochrome P450 2C19enzyme
LorlatinibUDP-glucuronosyltransferase 1-3enzyme
LorlatinibCytochrome P450 3A4enzyme
FedratinibP-glycoprotein 1transporter
FedratinibATP-binding cassette sub-family G member 2transporter
FedratinibSolute carrier organic anion transporter family member 1B1transporter
FedratinibSolute carrier organic anion transporter family member 1B3transporter
FedratinibPOU domain, class 2, transcription factor 2transporter
FedratinibMultidrug and toxin extrusion protein 1transporter
FedratinibMultidrug and toxin extrusion protein 2transporter
FedratinibCytochrome P450 3A4enzyme
FedratinibCytochrome P450 2C19enzyme
FedratinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
FedratinibTyrosine-protein kinase JAK2target
FedratinibReceptor-type tyrosine-protein kinase FLT3target
FedratinibTyrosine-protein kinase JAK1target
FedratinibCytochrome P450 2D6enzyme
GrapiprantProstaglandin E2 receptor EP4 subtypetarget
GrapiprantP-glycoprotein 1transporter
GrapiprantSerum albumincarrier
TazemetostatHistone-lysine N-methyltransferase EZH2target
TazemetostatP-glycoprotein 1transporter
TazemetostatMultidrug and toxin extrusion protein 1transporter
TazemetostatMultidrug and toxin extrusion protein 2transporter
TazemetostatCytochrome P450 3A Subfamilyenzyme
TazemetostatHistone-lysine N-methyltransferase EZH1target
TazemetostatATP-binding cassette sub-family G member 2transporter
TazemetostatCytochrome P450 3A4enzyme
RopivacaineSodium channel protein type 10 subunit alphatarget
RopivacaineCytochrome P450 1A2enzyme
RopivacaineCytochrome P450 2B6enzyme
RopivacaineCytochrome P450 3A4enzyme
MepivacaineSodium channel protein type 10 subunit alphatarget
AfatinibEpidermal growth factor receptortarget
AfatinibReceptor tyrosine-protein kinase erbB-2target
AfatinibReceptor tyrosine-protein kinase erbB-4target
AfatinibP-glycoprotein 1transporter
AfatinibATP-binding cassette sub-family G member 2transporter
CefiderocolPenicillin-binding protein 3target
CefiderocolPenicillin-binding protein 1Atarget
CefiderocolPenicillin-binding protein 1Btarget
CefiderocolPenicillin-binding protein 2target
CefiderocolD-alanyl-D-alanine carboxypeptidase DacBtarget
CefiderocolMexAB-OprM efflux systemtransporter
CefiderocolSerum albumincarrier
CefiderocolCatecholate siderophore receptor Fiutransporter
CefiderocolColicin I receptortransporter
CefiderocolPutative outer membrane ferric siderophore receptortransporter
CapmatinibCytochrome P450 3A4enzyme
CapmatinibAldehyde oxidaseenzyme
CapmatinibHepatocyte growth factor receptortarget
CapmatinibP-glycoprotein 1transporter
CapmatinibMultidrug and toxin extrusion protein 1transporter
CapmatinibMultidrug and toxin extrusion protein 2transporter
CapmatinibCytochrome P450 1A2enzyme
CapmatinibATP-binding cassette sub-family G member 2transporter
NirmatrelvirReplicase polyprotein 1abtarget
NirmatrelvirCytochrome P450 3A4enzyme
NirmatrelvirP-glycoprotein 1transporter
PiperacillinSolute carrier family 22 member 6transporter
PiperacillinPenicillin-binding protein 3target
PiperacillinPenicillin-binding protein 2Btarget
PiperacillinPenicillin-binding protein 2atarget
PiperacillinPenicillin-binding protein 1btarget
PiperacillinSolute carrier family 22 member 8transporter
HetacillinPenicillin-binding protein 2atarget
HetacillinPenicillin-binding protein 1btarget
HetacillinPenicillin-binding protein 3target
HetacillinPenicillin-binding protein 1Atarget
HetacillinPenicillin-binding protein 2Btarget
Benzylpenicilloyl polylysineHigh affinity immunoglobulin epsilon receptor subunit gammatarget
Benzylpenicilloyl polylysineHigh affinity immunoglobulin epsilon receptor subunit alphatarget
ZaleplonGamma-aminobutyric acid receptor subunit alpha-1target
ZaleplonCytochrome P450 3A4enzyme
ZaleplonAldehyde oxidaseenzyme
ZaleplonCytochrome P450 3A5enzyme
ZaleplonCytochrome P450 3A7enzyme
AmdinocillinPenicillin-binding protein 2target
AmdinocillinPenicillin-binding protein 2atarget
AmdinocillinPenicillin-binding protein 3target
AmdinocillinPenicillin-binding protein 1Atarget
AmdinocillinPenicillin-binding protein 2Btarget
AmdinocillinPenicillin-binding protein 1btarget
BacampicillinPenicillin-binding proteintarget
PivmecillinamPenicillin-binding protein 1Atarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
RoflumilastCytochrome P450 3A4enzyme
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
Oseltamivir acidNeuraminidasetarget
AcetamideAliphatic amidase expression-regulating proteintarget
3-MethoxybenzamidePoly [ADP-ribose] polymerase 1target
4-FluorobenzylamineTrypsin-1target
1-(4-Amidinophenyl)-3-(4-Chlorophenyl)UreaTrypsin-1target
Renzapride5-hydroxytryptamine receptor 3Atarget
Renzapride5-hydroxytryptamine receptor 4target
ItoprideDopamine D2 receptortarget
ItoprideAcetylcholinesterasetarget
ADL5859Delta-type opioid receptortarget
AsimadolineKappa-type opioid receptortarget
RilapladibPlatelet-activating factor acetylhydrolasetarget
INCB3284C-C chemokine receptor type 2target
APD7915-hydroxytryptamine receptor 2Atarget
Naronapride5-hydroxytryptamine receptor 4target
BedoradrineBeta-2 adrenergic receptortarget
Faropenem medoxomilPenicillin-binding protein 1Atarget
Faropenem medoxomilPenicillin-binding protein 2Btarget
Faropenem medoxomilPeptidoglycan synthase FtsItarget
SLx-4090Microsomal triglyceride transfer protein large subunittarget
SNX-5422Heat shock protein HSP 90-alphatarget
SNX-5422Heat shock protein HSP 90-betatarget
AvasimibeLiver carboxylesterase 1target
AvasimibeCytochrome P450 3A4enzyme
AvasimibeCytochrome P450 2C9enzyme
AvasimibeCytochrome P450 1A2enzyme
AvasimibeCytochrome P450 2C19enzyme
RemacemideCytochrome P450 3A4enzyme
Agomelatine5-hydroxytryptamine receptor 2Ctarget
AgomelatineMelatonin receptor type 1Btarget
AgomelatineMelatonin receptor type 1Atarget
AgomelatineCytochrome P450 2C9enzyme
AgomelatineCytochrome P450 1A2enzyme
SaredutantSubstance-K receptortarget
m-Hydroxyhippuric acidKynureninasetarget
PD-0325901Dual specificity mitogen-activated protein kinase kinase 1target
R-95845Gag-Pol polyproteintarget
R-95845Gag-Pol polyproteintarget
AndarineAndrogen receptortarget
PH-797804Mitogen-activated protein kinase 14target
AzidocillinPenicillin-binding protein 2atarget
AzidocillinPenicillin-binding protein 1btarget
AzidocillinPenicillin-binding protein 3target
AzidocillinPenicillin-binding protein 1Atarget
AzidocillinPenicillin-binding protein 2Btarget
AzidocillinSolute carrier family 22 member 5transporter
AzidocillinSolute carrier family 15 member 1transporter
AzidocillinSolute carrier family 15 member 2transporter
Cinitapride5-hydroxytryptamine receptor 1Atarget
Cinitapride5-hydroxytryptamine receptor 4target
Cinitapride5-hydroxytryptamine receptor 2Atarget
EnzalutamideSerum albumincarrier
EnzalutamideCytochrome P450 2C8enzyme
EnzalutamideCytochrome P450 3A4enzyme
EnzalutamideAndrogen receptortarget
EnzalutamideCytochrome P450 2C9enzyme
EnzalutamideCytochrome P450 2C19enzyme
EnzalutamideCytochrome P450 2B6enzyme
EnzalutamideCytochrome P450 3A5enzyme
EnzalutamideP-glycoprotein 1transporter
EnzalutamideThyroxine-binding globulincarrier
ArhalofenatePeroxisome proliferator-activated receptor gammatarget
MocetinostatHistone deacetylase 1target
MocetinostatHistone deacetylase 3target
MocetinostatHistone deacetylase 2target
EntinostatHistone deacetylasetarget
TecovirimatEnvelope protein F13target
TecovirimatUDP-glucuronosyltransferase 1-1enzyme
TecovirimatUDP-glucuronosyltransferase 1-4enzyme
RadotinibTyrosine-protein kinase ABL1target
BetrixabanP-glycoprotein 1transporter
BetrixabanCoagulation factor Xtarget
BetrixabanPotassium voltage-gated channel subfamily H member 2transporter
IniparibPoly [ADP-ribose] polymerase 1target
BelumosudilRho-associated protein kinase 2target
BelumosudilSerum albumincarrier
BelumosudilAlpha-1-acid glycoprotein 1carrier
BelumosudilRho-associated protein kinase 1target
BelumosudilCytochrome P450 3A4enzyme
BelumosudilCytochrome P450 2C8enzyme
BelumosudilCytochrome P450 2D6enzyme
BelumosudilUDP-glucuronosyltransferase 1-9enzyme
BelumosudilCytochrome P450 1A2enzyme
BelumosudilCytochrome P450 2C19enzyme
BelumosudilUDP-glucuronosyltransferase 1-1enzyme
BelumosudilP-glycoprotein 1transporter
BelumosudilATP-binding cassette sub-family G member 2transporter
BelumosudilSolute carrier organic anion transporter family member 1B1transporter
DofetilidePotassium channel subfamily K member 2target
DofetilidePotassium voltage-gated channel subfamily H member 2target
DofetilideATP-sensitive inward rectifier potassium channel 12target
DofetilideCytochrome P450 3A4enzyme
DofetilideSolute carrier family 22 member 2transporter
GlimepirideATP-sensitive inward rectifier potassium channel 1target
GlimepirideATP-sensitive inward rectifier potassium channel 11target
GlimepirideCytochrome P450 2C9enzyme
GlimepirideATP-binding cassette sub-family C member 8target
GlimepirideBile salt export pumptransporter
CefotiamPenicillin-binding protein 1Atarget
CefotiamSolute carrier family 22 member 6transporter
CefotiamSolute carrier family 22 member 8transporter
SulfanilamideDihydropteroate synthasetarget
CarmustineGlutathione reductase, mitochondrialtarget
CarmustineDNAtarget
CarmustineRNAtarget
SulfisoxazoleDihydropteroate synthasetarget
SulfisoxazoleCytochrome P450 2C9enzyme
CefmenoximePenicillin-binding protein 1Atarget
CefmenoximePeptidoglycan synthase FtsItarget
CefmetazolePenicillin binding protein 2atarget
CefmetazoleSerum albumincarrier
CefmetazoleSolute carrier family 15 member 1transporter
CefmetazoleSolute carrier family 15 member 2transporter
CefmetazolePenicillin-binding protein 1Atarget
CefmetazolePenicillin-binding protein 1Btarget
CefmetazolePeptidoglycan synthase FtsItarget
CefmetazoleD-alanyl-D-alanine carboxypeptidase DacAtarget
CefmetazoleD-alanyl-D-alanine carboxypeptidase DacCtarget
ArgatrobanProthrombintarget
ArgatrobanCytochrome P450 3A4enzyme
ArgatrobanCytochrome P450 3A5enzyme
ArgatrobanSerum albumincarrier
Argatrobanalpha1-acid glycoproteincarrier
FlucloxacillinPenicillin-binding protein 1Atarget
FlucloxacillinCytochrome P450 3A4enzyme
FlucloxacillinBile salt export pumptransporter
ErtapenemPenicillin-binding protein 2target
ErtapenemPeptidoglycan synthase FtsItarget
ErtapenemPenicillin-binding protein 1Atarget
ErtapenemD-alanyl-D-alanine carboxypeptidase DacCtarget
ErtapenemD-alanyl-D-alanine carboxypeptidase DacBtarget
ErtapenemPenicillin-binding protein 1Btarget
ErtapenemPeptidoglycan synthase FtsItarget
ErtapenemPenicillin-binding protein 2target
IbutilidePotassium voltage-gated channel subfamily H member 6target
IbutilideVoltage-dependent L-type calcium channel subunit beta-1target
IbutilideVoltage-dependent calcium channel gamma-1 subunittarget
IbutilideVoltage-dependent calcium channel subunit alpha-2/delta-1target
IbutilidePotassium voltage-gated channel subfamily H member 2target
IbutilideVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IbutilidePotassium channel subfamily K member 1target
IbutilidePotassium channel subfamily K member 6target
IbutilideATP-sensitive inward rectifier potassium channel 11target
IbutilidePotassium voltage-gated channel subfamily H member 7target
ChlorthalidoneSolute carrier family 12 member 1target
ChlorthalidoneSerum albumincarrier
ChlorthalidoneCarbonic anhydrase 1target
EthoxzolamideCarbonic anhydrase 1target
EthoxzolamideSolute carrier family 22 member 6transporter
EthoxzolamideCarbonic anhydrase 2target
EthoxzolamideCarbonic anhydrase 4target
EthoxzolamideCarbonic anhydrase 7target
EthoxzolamideCarbonic anhydrase 3target
Aminohippuric acidSolute carrier family 22 member 2transporter
Aminohippuric acidSolute carrier family 22 member 5transporter
Aminohippuric acidSolute carrier family 22 member 6transporter
Aminohippuric acidSolute carrier family 22 member 8transporter
Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 4transporter
Aminohippuric acidSolute carrier family 22 member 11transporter
Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
Aminohippuric acidMultidrug resistance-associated protein 1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
Aminohippuric acidMonocarboxylate transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 7transporter
SulfadiazineCytochrome P450 2C9enzyme
SulfadiazineDihydropteroate synthetasetarget
SulfadiazineCytochrome P450 2C8enzyme
SulfadiazineCytochrome P450 3A4enzyme
SorafenibSerine/threonine-protein kinase B-raftarget
SorafenibReceptor-type tyrosine-protein kinase FLT3target
SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
SorafenibVascular endothelial growth factor receptor 3target
SorafenibPlatelet-derived growth factor receptor betatarget
SorafenibMast/stem cell growth factor receptor Kittarget
SorafenibVascular endothelial growth factor receptor 2target
SorafenibCytochrome P450 3A4enzyme
SorafenibUDP-glucuronosyltransferase 1-9enzyme
SorafenibCytochrome P450 2B6enzyme
SorafenibCytochrome P450 2C8enzyme
SorafenibCytochrome P450 3A5enzyme
SorafenibCytochrome P450 3A7enzyme
SorafenibCytochrome P450 2C9enzyme
SorafenibMultidrug resistance-associated protein 4transporter
SorafenibP-glycoprotein 1transporter
SorafenibCanalicular multispecific organic anion transporter 1transporter
SorafenibATP-binding cassette sub-family G member 2transporter
SorafenibCytochrome P450 1A2enzyme
SorafenibCytochrome P450 2C19enzyme
SorafenibCytochrome P450 2D6enzyme
SorafenibUDP-glucuronosyltransferase 1-1enzyme
SorafenibRalA-binding protein 1transporter
SorafenibFibroblast growth factor receptor 1target
SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
SorafenibVascular endothelial growth factor receptor 1target
SorafenibSolute carrier organic anion transporter family member 1B1transporter
AcetohexamideATP-sensitive inward rectifier potassium channel 1target
AcetohexamideCarbonyl reductase [NADPH] 1enzyme
AcetohexamideSerum albumincarrier
AcetohexamideCytochrome P450 2C9enzyme
StreptozocinDNAtarget
StreptozocinP-glycoprotein 1transporter
StreptozocinSolute carrier family 2, facilitated glucose transporter member 2target
StreptozocinO-GlcNAcase BT_4395target
StreptozocinCytochrome P450 1A1enzyme
StreptozocinCytochrome P450 1A2enzyme
StreptozocinCytochrome P450 2E1enzyme
StreptozocinBifunctional protein NCOATtarget
CefpiramidePenicillin binding protein 2atarget
CefpiramideSerum albumincarrier
CefpiramidePeptidoglycan synthase FtsItarget
CefpiramidePenicillin-binding protein 1Btarget
CefpiramidePenicillin-binding protein 1Atarget
CefpiramidePenicillin-binding protein 1Btarget
CefpiramideD-alanyl-D-alanine carboxypeptidase DacCtarget
CefpiramidePenicillin-binding protein 1Atarget
LoracarbefPenicillin-binding protein 1Atarget
LoracarbefSolute carrier family 15 member 1transporter
LoracarbefSolute carrier family 15 member 2transporter
LoracarbefPenicillin-binding protein 3target
CefalotinPenicillin-binding protein 1Atarget
CefalotinD-alanyl-D-alanine carboxypeptidasetarget
CefalotinBeta-lactamasetarget
CefalotinSolute carrier family 22 member 5transporter
CefalotinSolute carrier family 15 member 1transporter
CefalotinSolute carrier family 15 member 2transporter
CefalotinSolute carrier family 22 member 6transporter
CefalotinSolute carrier family 22 member 8transporter
CefalotinSolute carrier family 22 member 11transporter
CefalotinSolute carrier family 22 member 7transporter
CefalotinPenicillin-binding protein 1Atarget
CefalotinPenicillin-binding protein 1btarget
CefalotinPenicillin-binding protein 3target
CefalotinPenicillin-binding protein 2atarget
CefalotinPenicillin-binding protein 2Btarget
CefalotinSerum albumincarrier
DicloxacillinSolute carrier family 15 member 1transporter
DicloxacillinSolute carrier family 15 member 2transporter
DicloxacillinPenicillin-binding protein 3target
DicloxacillinPenicillin-binding protein 1btarget
DicloxacillinPenicillin-binding protein 2atarget
DicloxacillinPenicillin-binding protein 3target
DicloxacillinPenicillin-binding protein 1Atarget
DicloxacillinPenicillin-binding protein 2Btarget
DicloxacillinCytochrome P450 3A4enzyme
DicloxacillinSerum albumincarrier
CefotaximePenicillin-binding protein 3target
CefotaximeSolute carrier family 15 member 1transporter
CefotaximeSolute carrier family 15 member 2transporter
CefotaximeSolute carrier family 22 member 6transporter
CefotaximeSolute carrier family 22 member 8transporter
CefotaximeSolute carrier family 22 member 11transporter
CefotaximeSolute carrier family 22 member 7transporter
CefotaximePenicillin-binding protein 1btarget
CefotaximePenicillin-binding protein 2atarget
CefotaximePenicillin-binding protein 1Atarget
CefotaximePenicillin-binding protein 2Btarget
CefotaximeSolute carrier family 22 member 6target
CefotaximeSolute carrier family 22 member 8target
CefotaximeSolute carrier family 22 member 11target
CefotaximeSolute carrier family 22 member 7target
CefotaximeSolute carrier family 15 member 1target
CefotaximeSerum albumintarget
CefotaximeBeta-lactamasetarget
CefotaximeSolute carrier family 15 member 2target
MetolazoneSolute carrier family 12 member 3target
ZafirlukastCysteinyl leukotriene receptor 1target
ZafirlukastCytochrome P450 2C9enzyme
ZafirlukastCytochrome P450 2C8enzyme
ZafirlukastProstaglandin G/H synthase 1enzyme
ZafirlukastCytochrome P450 3A4enzyme
ZafirlukastCytochrome P450 1A2enzyme
ZafirlukastCytochrome P450 2C19enzyme
ZafirlukastATP-binding cassette sub-family G member 2transporter
ZafirlukastCytochrome P450 2D6enzyme
BosentanEndothelin B receptortarget
BosentanEndothelin-1 receptortarget
BosentanCytochrome P450 3A4enzyme
BosentanCytochrome P450 2C9enzyme
BosentanBile salt export pumptransporter
CarbenicillinSolute carrier family 22 member 6transporter
CarbenicillinPenicillin-binding proteintarget
CarbenicillinCytosolic phospholipase A2enzyme
ValdecoxibProstaglandin G/H synthase 2target
ValdecoxibCytochrome P450 2C9enzyme
ValdecoxibCytochrome P450 3A4enzyme
ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
ValdecoxibCarbonic anhydrase 2target
ValdecoxibCarbonic anhydrase 3target
Cisapride5-hydroxytryptamine receptor 4target
Cisapride5-hydroxytryptamine receptor 3Atarget
CisapridePotassium voltage-gated channel subfamily H member 2target
Cisapride5-hydroxytryptamine receptor 2Atarget
CisaprideCytochrome P450 3A4enzyme
CisaprideCytochrome P450 3A5enzyme
CisaprideCytochrome P450 3A7enzyme
CisaprideCytochrome P450 2A6enzyme
CisaprideCytochrome P450 2B6enzyme
CisaprideCytochrome P450 2C19enzyme
CisaprideCytochrome P450 2C8enzyme
CisaprideCytochrome P450 2C9enzyme
CisaprideCytochrome P450 2D6enzyme
NafcillinCytochrome P450 1A2enzyme
NafcillinCytochrome P450 3A4enzyme
NafcillinSolute carrier family 22 member 6transporter
NafcillinPenicillin-binding protein 1btarget
NafcillinPenicillin-binding protein 2Btarget
NafcillinPenicillin-binding protein 2atarget
NafcillinPenicillin-binding protein 3target
NafcillinPenicillin-binding protein 1Atarget
NafcillinSerum albumincarrier
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
SulfacetamideDihydropteroate synthasetarget
SulfacetamideDihydropteroate synthase type-1target
SulfacetamideFolic acid synthesis protein FOL1target
SulfametopyrazineDihydropteroate synthetasetarget
CefiximePenicillin-binding protein 2target
CefiximeSolute carrier family 22 member 5transporter
CefiximeSolute carrier family 15 member 1transporter
CefiximeSolute carrier family 15 member 2transporter
ChlorpropamideATP-binding cassette sub-family C member 8target
ChlorpropamideSolute carrier family 15 member 1transporter
ChlorpropamideSolute carrier family 15 member 2transporter
ChlorpropamideSolute carrier family 22 member 6transporter
ChlorpropamideCytochrome P450 2C9enzyme
ChlorpropamideCytochrome P450 2C19enzyme
ChlorpropamideProstaglandin G/H synthase 1enzyme
CephaloglycinSolute carrier family 22 member 5transporter
CephaloglycinPenicillin-binding protein 1Btarget
AmprenavirHuman immunodeficiency virus type 1 proteasetarget
AmprenavirCytochrome P450 3A4enzyme
AmprenavirP-glycoprotein 1transporter
AmprenavirMultidrug resistance-associated protein 1transporter
AmprenavirCytochrome P450 2B6enzyme
AmprenavirCytochrome P450 2C19enzyme
AmprenavirCytochrome P450 2C9enzyme
AmprenavirCytochrome P450 2D6enzyme
AmprenavirCytochrome P450 3A5enzyme
AmprenavirSolute carrier organic anion transporter family member 1B1transporter
OxacillinPenicillin-binding protein 1Atarget
OxacillinSolute carrier family 15 member 1transporter
OxacillinSolute carrier family 15 member 2transporter
OxacillinPenicillin-binding protein 3target
OxacillinPenicillin-binding protein 2atarget
OxacillinPenicillin-binding protein 1Atarget
OxacillinPenicillin-binding protein 2Btarget
OxacillinPenicillin-binding protein 1btarget
OxacillinSolute carrier family 15 member 1target
OxacillinPenicillin-binding protein 2target
OxacillinSolute carrier family 15 member 2target
ZileutonArachidonate 5-lipoxygenasetarget
ZileutonCytochrome P450 2C9enzyme
ZileutonCytochrome P450 1A2enzyme
ZileutonCytochrome P450 3A4enzyme
ZileutonProstaglandin G/H synthase 1enzyme
ZileutonUDP-glucuronosyltransferase 1-9enzyme
ZileutonSerum albumincarrier
MeropenemD-alanyl-D-alanine carboxypeptidase DacBtarget
MeropenemBeta-lactamase OXA-10enzyme
MeropenemDipeptidase 1enzyme
SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
SulfasalazineCystine/glutamate transportertarget
SulfasalazineATP-binding cassette sub-family G member 2transporter
SulfasalazineCanalicular multispecific organic anion transporter 1transporter
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
SulfasalazineProstaglandin G/H synthase 2target
SulfasalazinePeroxisome proliferator-activated receptor gammatarget
SulfasalazineProstaglandin G/H synthase 1target
SulfasalazineArachidonate 5-lipoxygenasetarget
SulfasalazineProton-coupled folate transportertransporter
SulfasalazineThromboxane-A synthasetarget
SulfasalazinePhospholipase A2target
SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
CefaclorPenicillin-binding protein 1Atarget
CefaclorSolute carrier family 15 member 1transporter
CefaclorSolute carrier family 15 member 2transporter
CefaclorPenicillin-binding protein 3target
CefaclorMyeloperoxidaseenzyme
CefaclorSolute carrier family 22 member 8transporter
CefaclorBile salt export pumptransporter
TolazamideSulfonylurea receptor 1, Kir6.2target
TolazamideCytochrome P450 2C9enzyme
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideSodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 22 member 8transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
SulfapyridineDihydropteroate synthase type-1target
SulfapyridineCytochrome P450 2C9enzyme
ZonisamideSodium channel protein type 1 subunit alphatarget
ZonisamideCarbonic anhydrase 1target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
ZonisamideCytochrome P450 3A4enzyme
ZonisamideAldehyde oxidaseenzyme
ZonisamideAmine oxidase [flavin-containing] Btarget
ZonisamideCarbonic anhydrase 2target
ZonisamideCarbonic anhydrase 3target
ZonisamideCarbonic anhydrase 4target
ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
ZonisamideCarbonic anhydrase 6target
ZonisamideCarbonic anhydrase 7target
ZonisamideCarbonic anhydrase-related proteintarget
ZonisamideCarbonic anhydrase 9target
ZonisamideCarbonic anhydrase-related protein 10target
ZonisamideCarbonic anhydrase-related protein 11target
ZonisamideCarbonic anhydrase 12target
ZonisamideCarbonic anhydrase 13target
ZonisamideCarbonic anhydrase 14target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
ZonisamideSodium channel protein type 2 subunit alphatarget
ZonisamideSodium channel protein type 3 subunit alphatarget
ZonisamideSodium channel protein type 4 subunit alphatarget
ZonisamideSodium channel protein type 5 subunit alphatarget
ZonisamideSodium channel protein type 9 subunit alphatarget
ZonisamideSodium channel protein type 11 subunit alphatarget
ZonisamideSodium channel subunit beta-1target
ZonisamideSodium channel subunit beta-2target
ZonisamideSodium channel subunit beta-3target
ZonisamideSodium channel subunit beta-4target
ZonisamideAmine oxidase [flavin-containing] Atarget
ZonisamideCytochrome P450 2C19enzyme
ZonisamideUDP-glucuronosyltransferase 1-1enzyme
ZonisamideCytochrome P450 3A5enzyme
ZonisamideP-glycoprotein 1transporter
CeforanidePenicillin-binding protein 2target
TipranavirHuman immunodeficiency virus type 1 proteasetarget
TipranavirCytochrome P450 3A4enzyme
TipranavirCytochrome P450 2D6enzyme
TipranavirCytochrome P450 2C19enzyme
TipranavirBile salt export pumptransporter
TipranavirUDP-glucuronosyltransferase 1-1enzyme
TipranavirSolute carrier organic anion transporter family member 2B1transporter
TipranavirSolute carrier organic anion transporter family member 1B1transporter
TipranavirSolute carrier organic anion transporter family member 1B3transporter
TipranavirP-glycoprotein 1transporter
MezlocillinPenicillin-binding protein 1Atarget
MezlocillinPenicillin-binding protein 2target
MezlocillinPenicillin-binding protein 3target
CyclacillinSolute carrier family 22 member 5transporter
CyclacillinSolute carrier family 15 member 1transporter
CyclacillinSolute carrier family 15 member 2transporter
CyclacillinPenicillin-binding protein 1Atarget
CyclacillinPenicillin-binding protein 3target
CyclacillinPenicillin binding protein 2atarget
CyclacillinPenicillin-binding proteintarget
HydroxyureaRibonucleoside-diphosphate reductase large subunittarget
HydroxyureaCytochrome P450 2D6enzyme
GlyburideATP-binding cassette sub-family C member 9target
GlyburideBile salt export pumptarget
GlyburideATP-binding cassette sub-family A member 1target
GlyburideCystic fibrosis transmembrane conductance regulatortarget
GlyburideSulfonylurea receptor 1, Kir6.2target
GlyburideCytochrome P450 2C9enzyme
GlyburideCanalicular multispecific organic anion transporter 2transporter
GlyburideBile salt export pumptransporter
GlyburideP-glycoprotein 1transporter
GlyburideMultidrug resistance-associated protein 1transporter
GlyburideSolute carrier family 15 member 1transporter
GlyburideSolute carrier organic anion transporter family member 1A2transporter
GlyburideSolute carrier family 15 member 2transporter
GlyburideSolute carrier family 22 member 6transporter
GlyburideCanalicular multispecific organic anion transporter 1transporter
GlyburideATP-binding cassette sub-family G member 2transporter
GlyburideSolute carrier family 22 member 7transporter
GlyburideSolute carrier organic anion transporter family member 2B1transporter
GlyburideCytochrome P450 2C19enzyme
GlyburideCytochrome P450 3A4enzyme
GlyburideSerum albumincarrier
GlyburideMitochondrial ATP-sensitive potassium channeltarget
GlyburideCarnitine O-palmitoyltransferase 1, liver isoformtarget
GlyburideCytochrome P450 3A7enzyme
GlyburideCytochrome P450 3A5enzyme
GlyburideTransient receptor potential cation channel subfamily M member 4target
ProbenecidSolute carrier family 22 member 8target
ProbenecidSolute carrier family 22 member 11target
ProbenecidSerum albumincarrier
ProbenecidSolute carrier family 22 member 2transporter
ProbenecidSolute carrier family 22 member 1transporter
ProbenecidCanalicular multispecific organic anion transporter 2transporter
ProbenecidMultidrug resistance-associated protein 4transporter
ProbenecidMultidrug resistance-associated protein 5transporter
ProbenecidMonocarboxylate transporter 2transporter
ProbenecidSolute carrier family 22 member 5transporter
ProbenecidMultidrug resistance-associated protein 6transporter
ProbenecidMultidrug resistance-associated protein 1transporter
ProbenecidSolute carrier organic anion transporter family member 1A2transporter
ProbenecidMonocarboxylate transporter 1transporter
ProbenecidSodium/bile acid cotransportertransporter
ProbenecidSolute carrier family 22 member 6transporter
ProbenecidSolute carrier family 22 member 10transporter
ProbenecidSolute carrier family 22 member 8transporter
ProbenecidCanalicular multispecific organic anion transporter 1transporter
ProbenecidATP-binding cassette sub-family C member 11transporter
ProbenecidSolute carrier family 22 member 11transporter
ProbenecidSolute carrier organic anion transporter family member 1C1transporter
ProbenecidSolute carrier family 22 member 7transporter
ProbenecidSolute carrier family 22 member 6target
ProbenecidPannexin-1target
ProbenecidCytochrome P450 2C8enzyme
ProbenecidCytochrome P450 3A4enzyme
ProbenecidSolute carrier family 22 member 12transporter
ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
ProbenecidTaste receptor type 2 member 16target
ProbenecidUDP-glucuronosyltransferase 1-1enzyme
ProbenecidCytochrome P450 2C9enzyme
ProcainamideSodium channel protein type 5 subunit alphatarget
ProcainamideDNA (cytosine-5)-methyltransferase 1target
ProcainamideCytochrome P450 2D6enzyme
ProcainamideCholinesteraseenzyme
ProcainamideSolute carrier family 22 member 2transporter
ProcainamideSolute carrier family 22 member 1transporter
ProcainamideSolute carrier family 22 member 3transporter
ProcainamideSolute carrier family 22 member 5transporter
ProcainamideSolute carrier family 22 member 4transporter
ProcainamidePotassium voltage-gated channel subfamily H member 2target
ProcainamideMultidrug and toxin extrusion protein 1transporter
ProcainamideMultidrug and toxin extrusion protein 2transporter
TocainideSodium channel protein type 5 subunit alphatarget
TocainideSerum albumincarrier
TocainideCytochrome P450 1A2enzyme
AzlocillinPenicillin-binding protein 1Atarget
CefditorenPenicillin-binding protein 1Atarget
CefditorenPenicillin-binding protein 2Btarget
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
CefuroximePenicillin-binding protein 1Atarget
CefuroximeSolute carrier family 15 member 1transporter
CefuroximeSolute carrier family 15 member 2transporter
GliclazideATP-binding cassette sub-family C member 8target
GliclazideSerum albumincarrier
GliclazideVascular endothelial growth factor Atarget
GliclazideCytochrome P450 2C9enzyme
GliclazideCytochrome P450 2C19enzyme
PhenacemideSodium channel protein type 1 subunit alphatarget
TolbutamideATP-sensitive inward rectifier potassium channel 1target
TolbutamideCytochrome P450 2C19enzyme
TolbutamideCytochrome P450 2C9enzyme
TolbutamideCytochrome P450 2C8enzyme
TolbutamideATP-binding cassette sub-family C member 8target
TolbutamideSolute carrier family 15 member 1transporter
TolbutamideSolute carrier organic anion transporter family member 1A2transporter
TolbutamideSolute carrier family 15 member 2transporter
TolbutamideSolute carrier family 22 member 6transporter
TolbutamideSolute carrier organic anion transporter family member 2B1transporter
TolbutamideCytochrome P450 2C18enzyme
TolbutamideSerum albumincarrier
CefapirinPenicillin-binding protein 1Atarget
CefadroxilSolute carrier family 22 member 5transporter
CefadroxilSolute carrier family 15 member 1transporter
CefadroxilSolute carrier family 15 member 2transporter
CefadroxilSolute carrier family 22 member 6transporter
CefadroxilSolute carrier family 22 member 8transporter
CefadroxilPenicillin-binding protein 3target
CefadroxilPenicillin-binding protein 1Atarget
CefadroxilPenicillin-binding protein 1btarget
CefadroxilPenicillin-binding protein 2Btarget
DiclofenamideCarbonic anhydrase 1target
DiclofenamideCarbonic anhydrase 4target
DiclofenamideCarbonic anhydrase 2target
DiclofenamideCarbonic anhydrase 7target
DiclofenamideCarbonic anhydrase 3target
CefprozilPenicillin-binding protein 1Atarget
CefprozilPenicillin-binding protein 2xtarget
CefprozilPenicillin-binding protein 2Btarget
ProcarbazineDNAtarget
ProcarbazineXanthine dehydrogenase/oxidaseenzyme
ProcarbazineMonoamine oxidasetarget
MoclobemideAmine oxidase [flavin-containing] Atarget
MoclobemideCytochrome P450 2C19enzyme
MoclobemideCytochrome P450 2D6enzyme
MoclobemideAmine oxidase [flavin-containing] Aenzyme
MoclobemideAmine oxidase [flavin-containing] Benzyme
MoclobemideCytochrome P450 2C9enzyme
MoclobemideMonoamine oxidasetarget
MoclobemideAmine oxidase [flavin-containing] Btarget
LomustineDNAtarget
LomustineCytochrome P450 3A4enzyme
LomustineCytochrome P450 2D6enzyme
LomustineStathmin-4target
EncainideSodium channel protein type 5 subunit alphatarget
EncainideCytochrome P450 2D6enzyme
GliquidoneATP-binding cassette sub-family C member 8target
GliquidoneATP-sensitive inward rectifier potassium channel 8target
GliquidoneCytochrome P450 2C9enzyme
GlisoxepideATP-sensitive inward rectifier potassium channel 8target
GlisoxepideCytochrome P450 2C9enzyme
PractololBeta-1 adrenergic receptortarget
PractololCytochrome P450 2D6enzyme
SulfacytineDihydropteroate synthasetarget
SulfadoxineDihydropteroate synthetasetarget
SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
FosamprenavirHuman immunodeficiency virus type 1 proteasetarget
FosamprenavirCytochrome P450 3A4enzyme
QuinethazoneCarbonic anhydrase 1target
QuinethazoneCarbonic anhydrase 2target
QuinethazoneSolute carrier family 12 member 1target
QuinethazoneSolute carrier family 12 member 2target
QuinethazoneSolute carrier family 12 member 3target
CefamandoleSolute carrier family 22 member 6transporter
CefamandoleSolute carrier family 22 member 8transporter
CefamandoleSolute carrier family 22 member 11transporter
CefamandoleSolute carrier family 22 member 7transporter
CefamandolePenicillin-binding protein 2target
CefazolinSerum paraoxonase/arylesterase 1target
CefazolinSerum albumincarrier
CefazolinSolute carrier family 22 member 6transporter
CefazolinSolute carrier family 22 member 8transporter
CefazolinSolute carrier family 22 member 11transporter
CefazolinPenicillin-binding protein 1Atarget
CefazolinPenicillin-binding protein 1Btarget
CefazolinPenicillin-binding protein 2target
CefazolinPenicillin-binding protein 1Ctarget
CefazolinPeptidoglycan synthase FtsItarget
CefazolinMultidrug resistance-associated protein 4transporter
CefazolinThiopurine S-methyltransferaseenzyme
CefazolinInterleukin-15target
CefazolinInterleukin-2target
CefonicidSerum albumincarrier
CefonicidPenicillin-binding protein 1Atarget
CefonicidPeptidoglycan synthase FtsItarget
CefonicidPenicillin-binding protein 1Btarget
CefonicidD-alanyl-D-alanine carboxypeptidase DacBtarget
CefonicidPenicillin-binding protein 2target
CefoperazoneSerum albumincarrier
CefoperazoneSolute carrier family 22 member 6transporter
CefoperazoneSolute carrier family 22 member 8transporter
CefoperazoneSolute carrier family 22 member 11transporter
CefoperazoneSolute carrier family 22 member 7transporter
CefoperazonePeptidoglycan synthase FtsItarget
CefoperazonePenicillin-binding protein 1Btarget
CefoperazonePenicillin-binding protein 2target
CefoperazonePenicillin-binding protein 1Atarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacCtarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacAtarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacBtarget
CefoperazonePenicillin-binding protein 1Atarget
CefoperazonePenicillin-binding protein 1Btarget
CefotetanSerum albumincarrier
CefotetanPenicillin-binding protein 3target
CefoxitinPenicillin-binding protein 1Atarget
CefoxitinPenicillin-binding protein 1Btarget
CefoxitinPeptidoglycan synthase FtsItarget
CefoxitinD-alanyl-D-alanine carboxypeptidase DacAtarget
CefoxitinD-alanyl-D-alanine carboxypeptidase DacBtarget
CefoxitinD-alanyl-D-alanine carboxypeptidase DacCtarget
CefoxitinD-alanyl-D-alanine endopeptidasetarget
CefoxitinBeta-lactamaseenzyme
CefoxitinPenicillin-binding protein 3target
CefoxitinPenicillin-binding protein 1btarget
CefoxitinPenicillin-binding protein 2atarget
CefoxitinPenicillin-binding protein 1Atarget
CefoxitinPenicillin-binding protein 2Btarget
CefradineSolute carrier family 22 member 5transporter
CefradineSolute carrier family 15 member 1transporter
CefradineSolute carrier family 15 member 2transporter
CefradineSolute carrier family 22 member 6transporter
CefradinePenicillin-binding protein 1Atarget
CefradineCytochrome P450 3A4enzyme
CefradineMultidrug and toxin extrusion protein 1transporter
GlymidineATP-sensitive inward rectifier potassium channel 1target
GlymidineATP-binding cassette sub-family C member 8target
BezafibratePeroxisome proliferator-activated receptor alphatarget
BezafibrateSolute carrier organic anion transporter family member 1B1transporter
BezafibratePeroxisome proliferator-activated receptor deltatarget
BezafibratePeroxisome proliferator-activated receptor gammatarget
BezafibrateCytochrome P450 1A1enzyme
BezafibrateCytochrome P450 2C8enzyme
BezafibrateCytochrome P450 3A4enzyme
BezafibrateNuclear receptor subfamily 1 group I member 2target
BezafibrateRetinoic acid receptor RXR-alphatarget
BezafibrateRetinoic acid receptor RXR-betatarget
BezafibrateRetinoic acid receptor RXR-gammatarget
CefepimeSolute carrier family 22 member 5transporter
CefepimeSolute carrier family 15 member 1transporter
CefepimeSolute carrier family 15 member 2transporter
CefepimePenicillin-binding protein 2target
CefepimePeptidoglycan synthase FtsItarget
CefepimePenicillin-binding protein 3target
CefepimePenicillin-binding protein 2target
CefacetrilePenicillin-binding protein 1Atarget
CefacetrilePenicillin-binding protein 1Btarget
CefacetrileSolute carrier family 22 member 6transporter
CefacetrileSolute carrier family 22 member 8transporter
CeftibutenSolute carrier family 15 member 1transporter
CeftibutenSolute carrier family 15 member 2transporter
CeftibutenPeptidoglycan synthase FtsItarget
CeftibutenPenicillin-binding protein 1Atarget
CeftibutenPenicillin-binding protein 1Btarget
CeftibutenPenicillin-binding protein 2target
CeftibutenSolute carrier family 22 member 6transporter
CeftibutenSolute carrier family 22 member 8transporter
CefpodoximePeptidoglycan synthase FtsItarget
SulfamerazineDihydropteroate synthasetarget
SulfamerazineSerum albumincarrier
SulfamethazineDihydropteroate synthasetarget
SulfamethazineSerum albumincarrier
SulfamethazineArylamine N-acetyltransferaseenzyme
MeticillinMecA PBP2' (penicillin binding protein 2')target
MeticillinPenicillin-binding protein 2atarget
MeticillinPenicillin-binding protein 1btarget
MeticillinPenicillin-binding protein 2Btarget
MeticillinPenicillin-binding protein 3target
MeticillinPenicillin-binding protein 1Atarget
PivampicillinPenicillin-binding protein 1Atarget
SC-7402072 kDa type IV collagenasetarget
N,N-dimethylformamideChymotrypsin-like elastase family member 1target
N,N-dimethylformamideRenintarget
N,N-dimethylformamideCytochrome P450 2E1enzyme
AR-AO-14418Glycogen synthase kinase-3 betatarget
WAY-151693Collagenase 3target
MozenavirGag-Pol polyproteintarget
S-EthylisothioureaNitric oxide synthase oxygenasetarget
S-EthylisothioureaNitric oxide synthase, inducibletarget
S-EthylisothioureaNitric oxide synthase, endothelialtarget
GeldanamycinHeat shock protein HSP 90-alphatarget
GeldanamycinHeat shock protein HSP 90-betatarget
GeldanamycinEndoplasmintarget
N-BenzylformamideAlcohol dehydrogenase 1Btarget
VorinostatHistone deacetylase 1target
VorinostatHistone deacetylase 2target
VorinostatHistone deacetylase 3target
VorinostatHistone deacetylase 6target
VorinostatHistone deacetylase 8target
VorinostatAcetoin utilization proteintarget
VorinostatHistone deacetylasetarget
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideHistone deacetylase 8target
PiretanideSolute carrier family 12 member 1target
DoramapimodMitogen-activated protein kinase 14target
N-acetyl-N'-beta-D-glucopyranosyl ureaGlycogen phosphorylase, muscle formtarget
Cephalosporin CD-alanyl-D-alanine carboxypeptidasetarget
Cephalosporin CPenicillin-binding protein 1btarget
Cephalosporin CPenicillin-binding protein 1Atarget
Cephalosporin CPenicillin-binding protein 2Btarget
Cephalosporin CPenicillin-binding protein 2atarget
Cephalosporin CPenicillin-binding protein 3target
CyclohexylformamideAlcohol dehydrogenase 1Ctarget
CyclohexylformamideAlcohol dehydrogenase 4target
PhenacetinProstaglandin G/H synthase 1target
PhenacetinCytochrome P450 1A2enzyme
PhenacetinCytochrome P450 2D6enzyme
PhenacetinSolute carrier family 22 member 6transporter
PhenacetinCytochrome P450 1A1enzyme
PhenacetinCytochrome P450 2A13enzyme
PhenacetinCytochrome P450 2A6enzyme
PhenacetinCytochrome P450 2C19enzyme
PhenacetinCytochrome P450 2C9enzyme
PhenacetinCytochrome P450 2E1enzyme
PhenacetinCytochrome P450 3A4enzyme
ICI-164384Estrogen receptor betatarget
UreaArginase-1target
UreaCarbonic anhydrase 2target
UreaCatenin beta-1target
UreaSulfoxide reductase catalytic subunit YedYtarget
UreaUrea transporter 2transporter
UreaUrea transporter 1transporter
UreaDihydrofolate reductasetarget
Deacetoxycephalosporin CDeacetoxycephalosporin C synthasetarget
ThiocitrullineNitric oxide synthase, inducibletarget
FotemustineThioredoxin reductase 1, cytoplasmictarget
N-(Benzoylcarbamoyl)-beta-D-glucopyranosylamineGlycogen phosphorylase, muscle formtarget
AminoquinurideLethal factortarget
Paratoulene phosphateProto-oncogene tyrosine-protein kinase Srctarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideCalmodulintarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin C, slow skeletal and cardiac musclestarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin I, cardiac muscletarget
LatamoxefPenicillin-binding protein 3target
LatamoxefPenicillin-binding protein 1Atarget
LatamoxefPenicillin-binding protein 1Btarget
LatamoxefD-alanyl-D-alanine carboxypeptidase DacBtarget
CarboxinSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
NimesulideProstaglandin G/H synthase 2target
NimesulideGroup IIE secretory phospholipase A2target
NimesulideLactotransferrintarget
NimesulideCytochrome P450 3A4enzyme
CeliprololBeta-1 adrenergic receptortarget
CeliprololBeta-2 adrenergic receptortarget
CeliprololBeta-3 adrenergic receptortarget
CeliprololAlpha-2A adrenergic receptortarget
CeliprololAlpha-2B adrenergic receptortarget
CeliprololAlpha-2C adrenergic receptortarget
CeliprololCytochrome P450 2D6enzyme
MerimepodibInosine-5'-monophosphate dehydrogenasetarget
CeftobiproleMecAtarget
CeftobiprolePenicillin-binding protein 2xtarget
CeftobiprolePeptidoglycan synthase FtsItarget
BelinostatHistone deacetylasetarget
BelinostatCytochrome P450 1A2enzyme
BelinostatUDP-glucuronosyltransferase 1-1enzyme
BelinostatCytochrome P450 2C8enzyme
BelinostatCytochrome P450 2C9enzyme
BelinostatP-glycoprotein 1transporter
BelinostatCytochrome P450 3A4enzyme
EprotiromeThyroid hormone receptor alphatarget
EprotiromeThyroid hormone receptor betatarget
INCB13739Corticosteroid 11-beta-dehydrogenase isozyme 1target
SLV319Cannabinoid receptor 1target
CimicoxibProstaglandin G/H synthase 2target
CimicoxibProstaglandin G/H synthase 2enzyme
TanespimycinHeat shock protein HSP 90-alphatarget
TanespimycinHeat shock protein HSP 90-betatarget
TanespimycinSerum albumincarrier
AT9283Aurora kinase Atarget
AT9283Aurora kinase Btarget
KD3010Peroxisome proliferator-activated receptor deltatarget
XL765Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
XL765Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
XL765Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
XL765Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
XL765Serine/threonine-protein kinase mTORtarget
Silver sulfadiazineDNAtarget
Pimavanserin5-hydroxytryptamine receptor 2Atarget
Pimavanserin5-hydroxytryptamine receptor 2Ctarget
PimavanserinSigma non-opioid intracellular receptor 1target
PimavanserinCytochrome P450 3A4enzyme
PimavanserinCytochrome P450 3A5enzyme
PimavanserinCytochrome P450 2J2enzyme
PimavanserinCytochrome P450 2D6enzyme
Actelion-1Endothelin-1 receptortarget
VX-702Mitogen-activated protein kinase 14target
VX-702Tumor necrosis factortarget
VX-702Interleukin-1 betatarget
VX-702Interleukin-6target
AMG-131Peroxisome proliferator-activated receptor gammatarget
Naluzotan5-hydroxytryptamine receptor 1Atarget
UC-781Gag-Pol polyproteintarget
ResatorvidCytokine receptor common subunit betatarget
ResatorvidCytokine receptor common subunit gammatarget
LinifanibReceptor-type tyrosine-protein kinase FLT3target
LinifanibVascular endothelial growth factor receptor 1target
LinifanibVascular endothelial growth factor receptor 2target
LinifanibVascular endothelial growth factor receptor 3target
LinifanibMast/stem cell growth factor receptor Kittarget
LinifanibMacrophage colony-stimulating factor 1 receptortarget
VX-148Inosine-5'-monophosphate dehydrogenase 1target
VX-148Inosine-5'-monophosphate dehydrogenase 2target
SNS-314Aurora kinase Atarget
SNS-314Aurora kinase Ctarget
SulfathiazoleDihydropteroate synthetasetarget
SulfathiazoleCytochrome P450 19A1enzyme
SulfadimethoxineCytochrome P450 2C9enzyme
DoripenemDipeptidase 1enzyme
DoripenemPenicillin-binding protein 1Atarget
DoripenemPenicillin-binding protein 1Btarget
DoripenemPenicillin-binding protein 2target
DoripenemPenicillin-binding protein 3target
DoripenemPenicillin-binding protein 4target
DoripenemSolute carrier family 22 member 8transporter
LacosamideSodium channel protein type 9 subunit alphatarget
LacosamideSodium channel protein type 3 subunit alphatarget
LacosamideSodium channel protein type 10 subunit alphatarget
LacosamideCytochrome P450 2C19enzyme
LacosamideCytochrome P450 2C9enzyme
LacosamideCytochrome P450 3A4enzyme
UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
UdenafilCytochrome P450 3A4enzyme
UdenafilCytochrome P450 3A5enzyme
AR-9281Bifunctional epoxide hydrolase 2target
ElinogrelP2Y purinoceptor 12target
IndisulamCytochrome P450 2C9enzyme
IndisulamCytochrome P450 3A4enzyme
IndisulamCytochrome P450 2E1enzyme
IndisulamCytochrome P450 2D6enzyme
DeclopramideDNAtarget
DeclopramideDNA topoisomerase 2-alphatarget
DeclopramideDNA topoisomerase 2-betatarget
Ticalopride5-hydroxytryptamine receptor 4target
Ticalopride5-hydroxytryptamine receptor 3Atarget
AxitinibVascular endothelial growth factor receptor 1target
AxitinibVascular endothelial growth factor receptor 2target
AxitinibVascular endothelial growth factor receptor 3target
AxitinibCytochrome P450 3A4enzyme
AxitinibCytochrome P450 3A5enzyme
AxitinibCytochrome P450 1A2enzyme
AxitinibCytochrome P450 2C19enzyme
AxitinibUDP-glucuronosyltransferase 1-1enzyme
AxitinibP-glycoprotein 1transporter
AxitinibSolute carrier organic anion transporter family member 1B1transporter
ClazosentanEndothelin-1 receptortarget
SulfaphenazoleCytochrome P450 2C9enzyme
SulfaphenazoleCytochrome P450 2B6enzyme
SulfaphenazoleCytochrome P450 2C8enzyme
SulfaphenazoleCytochrome P450 2D6enzyme
SulfaphenazoleDihydropteroate synthasetarget
CapsaicinCytochrome P450 3A4enzyme
CapsaicinProstaglandin G/H synthase 2enzyme
CapsaicinMyeloperoxidaseenzyme
CapsaicinCytochrome P450 1A2enzyme
CapsaicinCytochrome P450 2E1enzyme
CapsaicinAmine oxidase [flavin-containing] Aenzyme
CapsaicinDopamine beta-hydroxylaseenzyme
CapsaicinGlutamine synthetaseenzyme
CapsaicinCholinesteraseenzyme
CapsaicinTransient receptor potential cation channel subfamily V member 1target
CapsaicinProhibitin-2target
MafenideCarbonic anhydrase 6target
NiclosamideDNAtarget
NiclosamideCytochrome P450 2C9enzyme
NiclosamideCytochrome P450 1A2enzyme
SulfameterDihydropteroate synthasetarget
PLX-4720Serine/threonine-protein kinase B-raftarget
TO-901317Oxysterols receptor LXR-betatarget
TO-901317Nuclear receptor coactivator 2target
TO-901317Retinoic acid receptor RXR-betatarget
TO-901317Oxysterols receptor LXR-alphatarget
TO-901317Nuclear receptor coactivator 1target
TO-901317Nuclear receptor subfamily 1 group I member 2target
SKF-91488Histamine N-methyltransferasetarget
NesbuvirGenome polyproteintarget
NesbuvirGenome polyproteintarget
GW-813893Prothrombintarget
GW-813893Coagulation factor Xtarget
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamideStromelysin-1target
S-23Androgen receptortarget
CGS-27023Macrophage metalloelastasetarget
CGS-27023Interstitial collagenasetarget
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamideStromelysin-1target
H-89cAMP-dependent protein kinase catalytic subunit alphatarget
H-89cAMP-dependent protein kinase inhibitor alphatarget
H-89Serine/threonine-protein kinase haspintarget
IDD594Aldose reductasetarget
Platensimycin3-oxoacyl-[acyl-carrier-protein] synthase 2target
2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACIDTrans-2-enoyl-ACP reductase IItarget
4-(2-AMINOETHYL)BENZENESULFONAMIDECarbonic anhydrase 2target
SulfamoxoleDihydropteroate synthetasetarget
SulfamoxoleCytochrome P450 2C9enzyme
MetiamideHistamine H2 receptortarget
VismodegibSmoothened homologtarget
VismodegibCytochrome P450 2C9enzyme
VismodegibCytochrome P450 3A4enzyme
VismodegibP-glycoprotein 1transporter
VismodegibCytochrome P450 2C8enzyme
VismodegibCytochrome P450 2C19enzyme
VismodegibATP-binding cassette sub-family G member 2transporter
VismodegibSerum albumincarrier
VismodegibAlpha-1-acid glycoprotein 1carrier
CabozantinibCytochrome P450 3A4enzyme
CabozantinibCytochrome P450 2C9enzyme
CabozantinibHepatocyte growth factor receptortarget
CabozantinibVascular endothelial growth factor receptor 2target
CabozantinibProto-oncogene tyrosine-protein kinase receptor Rettarget
CabozantinibCytochrome P450 2C8enzyme
VemurafenibSerum albumincarrier
VemurafenibAlpha-1-acid glycoprotein 1carrier
VemurafenibCytochrome P450 1A2enzyme
VemurafenibCytochrome P450 2D6enzyme
VemurafenibCytochrome P450 3A4enzyme
VemurafenibSerine/threonine-protein kinase B-raftarget
VemurafenibMultidrug resistance-associated protein 1transporter
VemurafenibATP-binding cassette sub-family G member 2transporter
VemurafenibCytochrome P450 2C9enzyme
VemurafenibCytochrome P450 2C8enzyme
VemurafenibCytochrome P450 2B6enzyme
VemurafenibP-glycoprotein 1transporter
RegorafenibCytochrome P450 3A4enzyme
RegorafenibUDP-glucuronosyltransferase 1-9enzyme
RegorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
RegorafenibVascular endothelial growth factor receptor 1target
RegorafenibVascular endothelial growth factor receptor 2target
RegorafenibVascular endothelial growth factor receptor 3target
RegorafenibMast/stem cell growth factor receptor Kittarget
RegorafenibPlatelet-derived growth factor receptor alphatarget
RegorafenibPlatelet-derived growth factor receptor betatarget
RegorafenibFibroblast growth factor receptor 1target
RegorafenibFibroblast growth factor receptor 2target
RegorafenibAngiopoietin-1 receptortarget
RegorafenibDiscoidin domain-containing receptor 2target
RegorafenibHigh affinity nerve growth factor receptortarget
RegorafenibEphrin type-A receptor 2target
RegorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
RegorafenibSerine/threonine-protein kinase B-raftarget
RegorafenibCytochrome P450 2C8enzyme
RegorafenibCytochrome P450 2C9enzyme
RegorafenibCytochrome P450 2B6enzyme
RegorafenibMitogen-activated protein kinase 11target
RegorafenibTyrosine-protein kinase FRKtarget
RegorafenibTyrosine-protein kinase ABL1target
RegorafenibP-glycoprotein 1transporter
RegorafenibATP-binding cassette sub-family G member 2transporter
RegorafenibUDP-glucuronosyltransferase 1-1enzyme
RegorafenibCytochrome P450 2C19enzyme
IndoraminAlpha-1A adrenergic receptortarget
GlibornurideCytochrome P450 2C9enzyme
CefaloridineSolute carrier family 22 member 6transporter
CefaloridineSolute carrier family 22 member 8transporter
BromoprideDopamine D2 receptortarget
BlinatumomabB-lymphocyte antigen CD19target
BlinatumomabT-cell surface glycoprotein CD3 delta chaintarget
LenvatinibVascular endothelial growth factor receptor 1target
LenvatinibVascular endothelial growth factor receptor 2target
LenvatinibVascular endothelial growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 1target
LenvatinibFibroblast growth factor receptor 2target
LenvatinibFibroblast growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 4target
LenvatinibPlatelet-derived growth factor receptor alphatarget
LenvatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
LenvatinibMast/stem cell growth factor receptor Kittarget
LenvatinibP-glycoprotein 1transporter
LenvatinibATP-binding cassette sub-family G member 2transporter
LenvatinibCytochrome P450 3A4enzyme
LenvatinibAldehyde oxidaseenzyme
LenvatinibCytochrome P450 2C8enzyme
LenvatinibCytochrome P450 2C9enzyme
LenvatinibCytochrome P450 1A2enzyme
LenvatinibCytochrome P450 2B6enzyme
LenvatinibCytochrome P450 2C19enzyme
LenvatinibSolute carrier family 22 member 6transporter
LenvatinibSolute carrier family 22 member 8transporter
LenvatinibSolute carrier family 22 member 2transporter
LenvatinibSolute carrier organic anion transporter family member 1B1transporter
LenvatinibBile salt export pumptransporter
LenvatinibCytochrome P450 2D6enzyme
LenvatinibSolute carrier organic anion transporter family member 1B3transporter
ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
ZucapsaicinCytochrome P450 1A2enzyme
ZucapsaicinCytochrome P450 2C19enzyme
ZucapsaicinCytochrome P450 2C9enzyme
ZucapsaicinCytochrome P450 2E1enzyme
DasabuvirNonstructural protein 5B (NS5B)target
DasabuvirCytochrome P450 2C8enzyme
DasabuvirCytochrome P450 3A4enzyme
DasabuvirCytochrome P450 2D6enzyme
DasabuvirUDP-glucuronosyltransferase 1-1enzyme
DasabuvirATP-binding cassette sub-family G member 2transporter
DasabuvirATP-binding cassette sub-family B member 5transporter
DasabuvirP-glycoprotein 1transporter
PropacetamolCholinesteraseenzyme
PropacetamolProstaglandin G/H synthase 1target
PropacetamolProstaglandin G/H synthase 2target
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolCannabinoid receptor 1target
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolUDP-glucuronosyltransferase 1-1enzyme
PropacetamolUDP-glucuronosyltransferase 1-6enzyme
PropacetamolUDP-glucuronosyltransferase 1-9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolUDP-glucuronosyltransferase 1-10enzyme
PropacetamolSulfotransferase 1A1enzyme
PropacetamolSulfotransferase 1A3/1A4enzyme
PropacetamolEstrogen sulfotransferaseenzyme
PropacetamolBile salt sulfotransferaseenzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
PropacetamolCytochrome P450 3A4enzyme
OmbitasvirNonstructural protein 5Atarget
OmbitasvirCytochrome P450 2C8enzyme
OmbitasvirP-glycoprotein 1transporter
OmbitasvirATP-binding cassette sub-family G member 2transporter
OmbitasvirUDP-glucuronosyltransferase 1-1enzyme
ParitaprevirNS3/4A proteintarget
ParitaprevirCytochrome P450 3A4enzyme
ParitaprevirCytochrome P450 3A5enzyme
ParitaprevirATP-binding cassette sub-family G member 2transporter
ParitaprevirP-glycoprotein 1transporter
ParitaprevirSolute carrier organic anion transporter family member 1B1transporter
ParitaprevirSolute carrier organic anion transporter family member 1B3transporter
ParitaprevirUDP-glucuronosyltransferase 1-1enzyme
CarindacillinPenicillin-binding proteintarget
SulbactamBeta-lactamasetarget
OsimertinibEpidermal growth factor receptortarget
OsimertinibP-glycoprotein 1transporter
OsimertinibATP-binding cassette sub-family G member 2transporter
OsimertinibCytochrome P450 3A4enzyme
OsimertinibCytochrome P450 1A2enzyme
AllantoinThyroxine-binding globulincarrier
NonivamideTransient receptor potential cation channel subfamily V member 1target
CefroxadineBeta-lactamaseenzyme
CefroxadinePenicillin-binding protein 1Btarget
GrazoprevirP-glycoprotein 1transporter
GrazoprevirSolute carrier organic anion transporter family member 1B1transporter
GrazoprevirSolute carrier organic anion transporter family member 1B3transporter
GrazoprevirCytochrome P450 3A4enzyme
GrazoprevirNS3/4A proteintarget
GrazoprevirSerum albumincarrier
GrazoprevirAlpha-1-acid glycoprotein 1carrier
AsunaprevirGenome polyproteintarget
AsunaprevirCytochrome P450 3A4enzyme
AsunaprevirCytochrome P450 3A5enzyme
AsunaprevirCytochrome P450 2A6enzyme
AsunaprevirCytochrome P450 2B6enzyme
AsunaprevirCytochrome P450 2C9enzyme
AsunaprevirCytochrome P450 2C19enzyme
AsunaprevirCytochrome P450 2D6enzyme
AsunaprevirSolute carrier organic anion transporter family member 1B1transporter
AsunaprevirSolute carrier organic anion transporter family member 1B3transporter
AsunaprevirSolute carrier organic anion transporter family member 2B1transporter
AsunaprevirP-glycoprotein 1transporter
PavinetantNeuromedin-K receptortarget
EncorafenibCytochrome P450 3A4enzyme
EncorafenibCytochrome P450 2C19enzyme
EncorafenibCytochrome P450 2D6enzyme
EncorafenibSerine/threonine-protein kinase B-raftarget
EncorafenibG1/S-specific cyclin-D1target
SpebrutinibTyrosine-protein kinase BTKtarget
PilaralisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DanoprevirGenome polyproteintarget
DanoprevirCytochrome P450 3A4enzyme
MirodenafilCytochrome P450 3A Subfamilyenzyme
TivozanibCytochrome P450 3A4enzyme
TivozanibSerum albumincarrier
TivozanibVascular endothelial growth factor receptor 1target
TivozanibVascular endothelial growth factor receptor 2target
TivozanibVascular endothelial growth factor receptor 3target
TivozanibMast/stem cell growth factor receptor Kittarget
TivozanibPlatelet-derived growth factor receptor betatarget
TivozanibP-glycoprotein 1transporter
TivozanibATP-binding cassette sub-family G member 2transporter
TivozanibReceptor-type tyrosine-protein kinase FLT3target
TivozanibPlatelet-derived growth factor receptor alphatarget
TivozanibProtein-tyrosine kinase 6target
TivozanibAngiopoietin-1 receptortarget
TivozanibFibroblast growth factor receptor 1target
TivozanibHepatocyte growth factor receptortarget
BaricitinibSolute carrier family 22 member 8transporter
BaricitinibATP-binding cassette sub-family G member 2transporter
BaricitinibMultidrug and toxin extrusion protein 2transporter
BaricitinibCytochrome P450 3A4enzyme
BaricitinibTyrosine-protein kinase JAK1target
BaricitinibTyrosine-protein kinase JAK2target
BaricitinibSolute carrier family 22 member 6transporter
BaricitinibSolute carrier family 22 member 2transporter
BaricitinibSolute carrier organic anion transporter family member 1B3transporter
BaricitinibProtein-tyrosine kinase 2-betatarget
BaricitinibTyrosine-protein kinase JAK3target
BaricitinibP-glycoprotein 1transporter
RelugolixSerum albumincarrier
RelugolixAlpha-1-acid glycoprotein 1carrier
RelugolixP-glycoprotein 1transporter
RelugolixATP-binding cassette sub-family G member 2transporter
RelugolixCytochrome P450 3A Subfamilyenzyme
RelugolixCytochrome P450 2C8enzyme
RelugolixCytochrome P450 2B6enzyme
RelugolixGonadotropin-releasing hormone receptortarget
InfigratinibCytochrome P450 3A4enzyme
InfigratinibMultidrug and toxin extrusion protein 1transporter
InfigratinibATP-binding cassette sub-family G member 2transporter
InfigratinibBile salt export pumptransporter
InfigratinibSolute carrier family 22 member 1transporter
InfigratinibSolute carrier family 22 member 2transporter
InfigratinibMultidrug and toxin extrusion protein 2transporter
InfigratinibP-glycoprotein 1transporter
InfigratinibSolute carrier organic anion transporter family member 1B1transporter
InfigratinibSolute carrier organic anion transporter family member 1B3transporter
InfigratinibApolipoproteinscarrier
InfigratinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
InfigratinibFibroblast growth factor receptor 1target
InfigratinibFibroblast growth factor receptor 2target
InfigratinibFibroblast growth factor receptor 3target
InfigratinibFibroblast growth factor receptor 4target
GlasdegibCytochrome P450 3A4enzyme
GlasdegibSmoothened homologtarget
GlasdegibCytochrome P450 2C8enzyme
GlasdegibUDP-glucuronosyltransferase 1-9enzyme
GlasdegibSerum albumincarrier
GlasdegibP-glycoprotein 1transporter
GlasdegibATP-binding cassette sub-family G member 2transporter
GlasdegibMultidrug and toxin extrusion protein 1transporter
GlasdegibMultidrug and toxin extrusion protein 2transporter
VoxilaprevirCytochrome P450 3A4enzyme
VoxilaprevirCytochrome P450 1A2enzyme
VoxilaprevirCytochrome P450 2C8enzyme
VoxilaprevirNS3/4A proteintarget
VoxilaprevirP-glycoprotein 1transporter
VoxilaprevirATP-binding cassette sub-family G member 2transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B1transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B3transporter
LandiololCytochrome P450 2D6enzyme
ForetinibHepatocyte growth factortarget
ForetinibVascular endothelial growth factor receptor 2target
ForetinibCytochrome P450 3A Subfamilyenzyme
NavitoclaxApoptosis regulator Bcl-2target
NavitoclaxBcl-2-like protein 2target
NavitoclaxBcl2 antagonist of cell deathtarget
AlvespimycinHeat shock protein HSP 90-alphatarget
RacloprideDopamine D2 receptortarget
SparsentanAngiotensinogentarget
SparsentanEndothelin-1 receptortarget
Nelotanserin5-hydroxytryptamine receptor 2Atarget
PiperineNuclear receptor subfamily 1 group I member 2target
PiperineCytochrome P450 3A4enzyme
PiperineP-glycoprotein 1transporter
PilsicainideBile salt export pumptransporter
DaporinadNicotinamide phosphoribosyltransferasetarget
AmuvatinibMast/stem cell growth factor receptor Kittarget
AmuvatinibHepatocyte growth factor receptortarget
AmuvatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
AmuvatinibPlatelet-derived growth factor receptor alphatarget
AmuvatinibReceptor-type tyrosine-protein kinase FLT3target
AmuvatinibDNA repair protein RAD51 homolog 1target
QuizartinibReceptor-type tyrosine-protein kinase FLT3target
RamatrobanProstaglandin D2 receptor 2target
RipasudilRho-associated protein kinase 1target
RipasudilRho-associated protein kinase 2target
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
CarbutamideCytochrome P450 2C9enzyme
MetahexamideCytochrome P450 2C9enzyme
EpanololCytochrome P450 2D6enzyme
GlecaprevirCytochrome P450 3A Subfamilyenzyme
GlecaprevirUDP-glucuronosyltransferase 1-1enzyme
GlecaprevirP-glycoprotein 1transporter
GlecaprevirATP-binding cassette sub-family G member 2transporter
GlecaprevirSolute carrier organic anion transporter family member 1B1transporter
GlecaprevirSolute carrier organic anion transporter family member 1B3transporter
GlecaprevirNS3 proteasetarget
GlecaprevirCytochrome P450 3A4enzyme
SB-2699705-hydroxytryptamine receptor 7target
Acetyl sulfisoxazoleDihydropteroate synthasetarget
Acetyl sulfisoxazoleCytochrome P450 2C9enzyme
SC-236Cyclooxygenase 2target
SC-236Nuclear factor NF-kappa-B complextarget
NS-398Cyclooxygenase 2target
Piflufolastat F 18Glutamate carboxypeptidase 2target
RipretinibMast/stem cell growth factor receptor Kittarget
RipretinibPlatelet-derived growth factor receptor betatarget
RipretinibAngiopoietin-1 receptortarget
RipretinibVascular endothelial growth factor receptor 2target
RipretinibSerine/threonine-protein kinase B-raftarget
RipretinibPlatelet-derived growth factor receptor alphatarget
RipretinibCytochrome P450 2C8enzyme
RipretinibPlatelet-derived growth factor receptor alphaenzyme
RipretinibSerum albumincarrier
Ripretinibalpha1-acid glycoproteincarrier
RipretinibP-glycoprotein 1transporter
RipretinibATP-binding cassette sub-family G member 2transporter
RipretinibMultidrug and toxin extrusion protein 1transporter
RipretinibCytochrome P450 3A4enzyme
RipretinibCytochrome P450 2D6enzyme
RipretinibCytochrome P450 2E1enzyme
CeralasertibSerine/threonine-protein kinase ATRtarget
AbrocitinibCytochrome P450 2C19enzyme
AbrocitinibCytochrome P450 2C9enzyme
AbrocitinibCytochrome P450 3A4enzyme
AbrocitinibCytochrome P450 2B6enzyme
AbrocitinibTyrosine-protein kinase JAK1target
AbrocitinibP-glycoprotein 1transporter
AbrocitinibSolute carrier family 22 member 1transporter
AbrocitinibTyrosine-protein kinase JAK2target
AbrocitinibTyrosine-protein kinase JAK3target
AbrocitinibNon-receptor tyrosine-protein kinase TYK2target
AbrocitinibSerum albumincarrier
AbrocitinibSolute carrier family 22 member 8transporter
VercirnonC-C chemokine receptor type 9target
TMC-310911HIV-1 proteasetarget
AlmonertinibReceptor protein-tyrosine kinasetarget