Isoxazoles

All categories

Name: Isoxazoles
Accession Number: DBCAT000628
Description: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.
Drugs: Drug Drug Description
Cycloserine A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI).
Isocarboxazid A monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs.
Leflunomide A pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
MK-8777 MK-8777 is under investigation in clinical trial NCT00610649 (Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder...
Paliperidone An atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.
Pentizidone Pentizidone is a small molecule drug. Pentizidone has a monoisotopic molecular weight of 184.08 Da.
Zonisamide A sulfonamide anticonvulsant used to treat partial seizures.
Drugs & Drug Targets: Drug Target Type
Cycloserine Glutamate receptor ionotropic, NMDA 1 target
Cycloserine Proton-coupled amino acid transporter 2 transporter
Cycloserine Aromatic-L-amino-acid decarboxylase enzyme
Cycloserine Alanine racemase target
Cycloserine D-alanine--D-alanine ligase A target
Isocarboxazid Amine oxidase [flavin-containing] A target
Isocarboxazid Amine oxidase [flavin-containing] B target
Isocarboxazid Monoamine oxidase target
Leflunomide Dihydroorotate dehydrogenase (quinone), mitochondrial target
Leflunomide Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Leflunomide Protein-tyrosine kinase 2-beta target
Leflunomide Aryl hydrocarbon receptor target
Leflunomide Cytochrome P450 2C9 enzyme
Leflunomide Cytochrome P450 1A2 enzyme
Leflunomide Dihydroorotate dehydrogenase (quinone), mitochondrial target
Paliperidone ATP-dependent translocase ABCB1 transporter
Paliperidone Cytochrome P450 3A5 enzyme
Paliperidone Cytochrome P450 2D6 enzyme
Paliperidone Cytochrome P450 3A4 enzyme
Paliperidone 5-hydroxytryptamine receptor 7 target
Paliperidone 5-hydroxytryptamine receptor 2C target
Paliperidone 5-hydroxytryptamine receptor 1D target
Paliperidone 5-hydroxytryptamine receptor 1A target
Paliperidone Alpha-2C adrenergic receptor target
Paliperidone Alpha-2B adrenergic receptor target
Paliperidone Alpha-2A adrenergic receptor target
Paliperidone Dopamine receptor D1 target
Paliperidone Dopamine receptor D4 target
Paliperidone Dopamine receptor D3 target
Paliperidone Alpha-1B adrenergic receptor target
Paliperidone Alpha-1A adrenergic receptor target
Paliperidone Histamine H1 receptor target
Paliperidone 5-hydroxytryptamine receptor 2A target
Paliperidone Dopamine receptor D2 target
Zonisamide Sodium channel regulatory subunit beta-4 target
Zonisamide Amine oxidase [flavin-containing] A target
Zonisamide Carbonic anhydrase 7 target
Zonisamide UDP-glucuronosyltransferase 1A1 enzyme
Zonisamide Cytochrome P450 3A5 enzyme
Zonisamide ATP-dependent translocase ABCB1 transporter
Zonisamide GABA(A) Receptor Benzodiazepine Binding Site target
Zonisamide Voltage-gated sodium channel alpha subunit target
Zonisamide Carbonic anhydrase 6 target
Zonisamide Carbonic anhydrase 5B, mitochondrial target
Zonisamide Carbonic anhydrase 5A, mitochondrial target
Zonisamide Carbonic anhydrase 4 target
Zonisamide Carbonic anhydrase 3 target
Zonisamide Carbonic anhydrase 2 target
Zonisamide Amine oxidase [flavin-containing] B target
Zonisamide Aldehyde oxidase enzyme
Zonisamide Cytochrome P450 3A4 enzyme
Zonisamide Voltage-dependent T-type calcium channel subunit alpha-1G target
Zonisamide Carbonic anhydrase 1 target
Zonisamide Sodium channel protein type 1 subunit alpha target
Zonisamide Sodium channel regulatory subunit beta-3 target
Zonisamide Sodium channel regulatory subunit beta-2 target
Zonisamide Sodium channel regulatory subunit beta-1 target
Zonisamide Sodium channel protein type 11 subunit alpha target
Zonisamide Sodium channel protein type 9 subunit alpha target
Zonisamide Sodium channel protein type 5 subunit alpha target
Zonisamide Sodium channel protein type 4 subunit alpha target
Zonisamide Sodium channel protein type 3 subunit alpha target
Zonisamide Sodium channel protein type 2 subunit alpha target
Zonisamide Voltage-dependent T-type calcium channel subunit alpha-1I target
Zonisamide Voltage-dependent T-type calcium channel subunit alpha-1H target
Zonisamide Carbonic anhydrase 14 target
Zonisamide Carbonic anhydrase 13 target
Zonisamide Carbonic anhydrase 12 target
Zonisamide Carbonic anhydrase-related protein 11 target
Zonisamide Carbonic anhydrase-related protein 10 target
Zonisamide Carbonic anhydrase 9 target
Zonisamide Carbonic anhydrase-related protein target
Zonisamide Cytochrome P450 2C19 enzyme

Drug	Drug Description
Cycloserine	A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI).
Isocarboxazid	A monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs.
Leflunomide	A pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
MK-8777	MK-8777 is under investigation in clinical trial NCT00610649 (Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder...
Paliperidone	An atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.
Pentizidone	Pentizidone is a small molecule drug. Pentizidone has a monoisotopic molecular weight of 184.08 Da.
Zonisamide	A sulfonamide anticonvulsant used to treat partial seizures.

Isoxazoles

Create a free account or log in to explore the full data card.