Name
Oxazines
Accession Number
DBCAT000803
Description

Six-membered heterocycles containing an oxygen and a nitrogen.

Drugs
DrugDrug Description
TimololA non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
IfosfamideAn alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
RivaroxabanA factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
ViltolarsenAn antisense phosphorodiamidate morpholino oligonucleotide specific for exon 53 of the human DMD gene that is capable of inducing exon 53 skipping to produce a functional truncated dystrophin protein in Duchenne muscular dystrophy patients with specific underlying mutations.
CasimersenAn antisense phosphorodiamidate morpholino oligonucleotide used to treat Duchenne muscular dystrophy patients with mutations amenable to exon 45 skipping.
ReboxetineA drug used for the acute treatment of major depression and for maintenance therapy of depression.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
AprepitantA substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
MoricizineAn antiarrhythmic used to treat arrhythmias.
PhenmetrazineUsed as an anorectic in the treatment of obesity.
DextromoramideAn opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
PhendimetrazineA sympathomimetic amine used as adjunct therapy for the short term management of exogenous obesity.
Mdl 101,146Not Available
LY-294002Specific inhibitor of phosphatidylinositol 3-kinase.
3-(N-morpholino)propanesulfonic acidNot Available
2-(N-morpholino)ethanesulfonic acidNot Available
TanaprogetTanaproget (NSP-989) is an investigational non-steroidal progestin. It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most...
APD791For the treatment and prophylaxis of arterial thrombosis.
CanertinibInvestigated for use/treatment in breast cancer and lung cancer.
ApilimodInvestigated for use/treatment in crohn's disease and psoriasis and psoriatic disorders.
PalifosfamideInvestigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.
EteplirsenAn antisense oligonucleotide used to treat Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation of the DMD gene that is amenable to exon 51 skipping.
TirbanibulinA tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp.
GlufosfamideInvestigated for use/treatment in pancreatic cancer, solid tumors, breast cancer, colorectal cancer, brain cancer, lung cancer, ovarian cancer, and sarcoma.
CetilistatInvestigated for use/treatment in obesity.
QuarfloxinInvestigated for use/treatment in leukemia (lymphoid).
FosaprepitantAn antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy.
ReversineNot Available
FominobenFominoben is an antitussive agent.
AmorolfineA morpholine derivative commonly applied as a lacquer for onychomycosis but is also used for superficial dermatomycosis.
OlodaterolA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
PinaveriumA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
EdivoxetineEdivoxetine is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant treatment....
ViloxazineA selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children.
LubazodoneLubazodone (YM-992, YM-35,995) is an arylpiperazine antidepressant which was being developed as a treatment for depression and obsessive compulsive disorder, and reached phase II clinical trials, but was discontinued. It...
PholcodineAn opioid antitussive used to suppress unproductive coughing.
MolsidomineA long-acting vasodilator used to treat angina pectoris, including in association with left heart failure and acute myocardial infarction.
PramocaineA local anesthetic and antipruritic agent found in various topical preparations.
BuparlisibBuparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, Lung Cancer, Solid Tumors, and Breast Cancer, among others.
MosaprideA prokinetic 5-HT4 receptor agonist used to stimulate gastric motility.
GSK-2636771GSK2636771 has been used in trials studying the treatment of CANCER, LYMPHOMA, Solid Neoplasm, Recurrent Solid Neoplasm, and Advanced Malignant Neoplasm, among others.
BasmisanilBasmisanil has been used in trials studying the treatment and basic science of Down Syndrome.
CUDC-907CUDC-907 has been used in trials studying the treatment of Lymphoma, Solid Tumors, BREAST CANCER, Multiple Myeloma, and NUT Midline Carcinoma, among others.
GedatolisibGedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer, Breast Cancer, Advanced Cancer, and Endometrial Cancer, among others.
VistusertibVistusertib is under investigation for the treatment of Advanced Gastric Adenocarcinoma.
EpelsibanEpelsiban has been investigated for the treatment of Premature Ejaculation.
FostamatinibA spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
CC-220CC-220 has been used in trials studying the treatment of Systemic Lupus Erythematosus.
LandiololAn ultra short-acting selective beta-blocker used for rapid ventricular rate control in cases of supraventricular tachycardia.
EsreboxetineEsreboxetine has been used in trials studying the treatment and basic science of Fibromyalgia.
RimacalibRimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).
AZD-8055AZD8055 has been used in trials studying the treatment of Cancer, Lymphomas, Solid Tumors, MALIGNANT GLIOMA, and brainstem glioma, among others.
ZoliflodacinZoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
TazemetostatA methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
VS-5584VS-5584 has been used in trials studying the treatment of Lymphoma, Metastatic Cancer, and Non Hematologic Cancers.
ApratastatTmi 005 is under investigation in clinical trial NCT00095342 (Study Evaluating TMI-005 in Active Rheumatoid Arthritis).
PKI-179PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors.
LinsidomineNot Annotated
OxaflozaneNot Annotated
MoroxydineNot Annotated
Tiemonium iodideNot Annotated
MorpholineNot Annotated
XamoterolXamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but...
WIN 55212-2WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It...
Baloxavir marboxilA polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.
MorpholinylmercaptobenzothiazoleNot Annotated
SUVN-G3031SUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-G3031 in Healthy Subjects).
CeralasertibCeralasertib is under investigation in clinical trial NCT03682289 (Phase II Trial of AZD6738 Alone and in Combination With Olaparib).
SatavaptanSatavaptan is under investigation in clinical trial NCT00359437 (Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver).
SerabelisibSerabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics of TAK-117 (MLN1117)...
PemigatinibA kinase inhibitor used to treat locally advanced or metastatic, unresectable cholangiocarcinoma in previously treated adult patients.
RadavirsenRadavirsen is under investigation in clinical trial NCT01375985 (Safety Study of Single Administration Intravenous Treatment for Influenza).
BaloxavirBaloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).
KZR-616KZR-616 is under investigation in clinical trial NCT04033926 (A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis).
AclimostatAclimostat is under investigation in clinical trial NCT03254368 (Study to Assess the Effects and Safety of ZGN-1061 in Overweight and Obese Participants With Type 2 Diabetes).
ASTX660ASTX660 is under investigation in clinical trial NCT02503423 (Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas).
LazertinibLazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
E-52862Not Annotated
Drugs & Drug Targets
DrugTargetType
TimololBeta-1 adrenergic receptortarget
TimololBeta-2 adrenergic receptortarget
TimololCytochrome P450 2D6enzyme
TimololP-glycoprotein 1transporter
TimololCytochrome P450 2C19enzyme
TimololLysozymetarget
IfosfamideCytochrome P450 2B6enzyme
IfosfamideDNAtarget
IfosfamideCytochrome P450 3A4enzyme
IfosfamideCytochrome P450 3A5enzyme
IfosfamideCytochrome P450 2C9enzyme
IfosfamideCytochrome P450 2C8enzyme
IfosfamideCytochrome P450 2A6enzyme
IfosfamideCytochrome P450 2C19enzyme
IfosfamideCytochrome P450 2C18enzyme
IfosfamideProstaglandin G/H synthase 1enzyme
IfosfamideNuclear receptor subfamily 1 group I member 2target
RivaroxabanCoagulation factor Xtarget
RivaroxabanCytochrome P450 3A4enzyme
RivaroxabanCytochrome P450 2J2enzyme
RivaroxabanP-glycoprotein 1transporter
RivaroxabanCytochrome P450 3A5enzyme
RivaroxabanATP-binding cassette sub-family G member 2transporter
ViltolarsenDMD gene (exon 53 viltolarsen target site)target
CasimersenDMD gene (exon 45 casimersen target site)target
CasimersenCytochrome P450 3A4enzyme
CasimersenCytochrome P450 3A5enzyme
CasimersenCytochrome P450 2C9enzyme
CasimersenCytochrome P450 2C19enzyme
ReboxetineSodium-dependent noradrenaline transportertarget
ReboxetineCytochrome P450 3A4enzyme
ReboxetineCytochrome P450 2D6enzyme
ReboxetineP-glycoprotein 1transporter
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzSerum albumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1-1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
AprepitantNeurokinin 1 receptortarget
AprepitantCytochrome P450 3A4enzyme
AprepitantCytochrome P450 2C9enzyme
AprepitantCytochrome P450 2C19enzyme
MoricizineSodium channel protein type 5 subunit alphatarget
PhenmetrazineSodium-dependent noradrenaline transportertarget
PhenmetrazineSodium-dependent dopamine transportertarget
PhendimetrazineAlpha-1A adrenergic receptortarget
PhendimetrazineAlpha-1B adrenergic receptortarget
PhendimetrazineSodium-dependent noradrenaline transportertarget
Mdl 101,146Chymotrypsin-like elastase family member 1target
Mdl 101,146Neutrophil elastasetarget
LY-294002Serine/threonine-protein kinase pim-1target
LY-294002Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
3-(N-morpholino)propanesulfonic acidPhosphoribosylglycinamide formyltransferase 2target
3-(N-morpholino)propanesulfonic acidAlpha-xylosidasetarget
3-(N-morpholino)propanesulfonic acidGranulysintarget
2-(N-morpholino)ethanesulfonic acidChymasetarget
2-(N-morpholino)ethanesulfonic acidGlutathione S-transferase Ptarget
2-(N-morpholino)ethanesulfonic acidAcetylcholinesterasetarget
2-(N-morpholino)ethanesulfonic acidGlutamine--fructose-6-phosphate aminotransferase [isomerizing]target
2-(N-morpholino)ethanesulfonic acidDihydrofolate reductasetarget
2-(N-morpholino)ethanesulfonic acidCopper-containing nitrite reductasetarget
2-(N-morpholino)ethanesulfonic acidCorticosteroid 11-beta-dehydrogenase isozyme 1target
2-(N-morpholino)ethanesulfonic acidHydroxylamine reductasetarget
2-(N-morpholino)ethanesulfonic acidDiaminopimelate decarboxylasetarget
2-(N-morpholino)ethanesulfonic acidAlpha-xylosidasetarget
2-(N-morpholino)ethanesulfonic acidLimonene-1,2-epoxide hydrolasetarget
2-(N-morpholino)ethanesulfonic acidMannan endo-1,4-beta-mannosidasetarget
2-(N-morpholino)ethanesulfonic acidBeta-1,4-galactosyltransferase 1target
2-(N-morpholino)ethanesulfonic acidTyrosine-protein kinase transforming protein Abltarget
2-(N-morpholino)ethanesulfonic acidBifunctional protein GlmUtarget
2-(N-morpholino)ethanesulfonic acidThiol:disulfide interchange protein DsbCtarget
2-(N-morpholino)ethanesulfonic acidGlyceraldehyde-3-phosphate dehydrogenase Atarget
2-(N-morpholino)ethanesulfonic acid(S)-mandelate dehydrogenasetarget
2-(N-morpholino)ethanesulfonic acidDissimilatory copper-containing nitrite reductasetarget
2-(N-morpholino)ethanesulfonic acid33 kDa chaperonintarget
2-(N-morpholino)ethanesulfonic acidFree methionine-R-sulfoxide reductasetarget
2-(N-morpholino)ethanesulfonic acidOrnithine cyclodeaminasetarget
2-(N-morpholino)ethanesulfonic acidDihydropteridine reductasetarget
2-(N-morpholino)ethanesulfonic acidArgininosuccinate lyasetarget
2-(N-morpholino)ethanesulfonic acidO-acetyl-ADP-ribose deacetylasetarget
2-(N-morpholino)ethanesulfonic acidADP-ribosylation factor-like protein 3target
2-(N-morpholino)ethanesulfonic acidBeta-lactamasetarget
2-(N-morpholino)ethanesulfonic acid3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsCtarget
2-(N-morpholino)ethanesulfonic acidLethal(3)malignant brain tumor-like protein 1target
2-(N-morpholino)ethanesulfonic acidCholinesterasetarget
2-(N-morpholino)ethanesulfonic acidRibonuclease Ztarget
2-(N-morpholino)ethanesulfonic acidPeroxiredoxin-6target
2-(N-morpholino)ethanesulfonic acidHypothetical gliding proteintarget
2-(N-morpholino)ethanesulfonic acidProlyl endopeptidase Peptarget
2-(N-morpholino)ethanesulfonic acidPulmonary surfactant-associated protein A1target
2-(N-morpholino)ethanesulfonic acidManganese catalasetarget
2-(N-morpholino)ethanesulfonic acidChorismate mutase AroHtarget
2-(N-morpholino)ethanesulfonic acidPutative cytochrome P450target
2-(N-morpholino)ethanesulfonic acidInterferon-inducible GTPase 5target
TanaprogetProgesterone receptortarget
APD7915-hydroxytryptamine receptor 2Atarget
CanertinibEpidermal growth factor receptortarget
PalifosfamideDNA (cytosine-5)-methyltransferase 1target
EteplirsenDMD-001 gene (exon 51 target site)target
TirbanibulinProto-oncogene tyrosine-protein kinase Srctarget
TirbanibulinTubulin beta chaintarget
TirbanibulinCytochrome P450 3A4enzyme
TirbanibulinCytochrome P450 2C8enzyme
TirbanibulinCytochrome P450 1A2enzyme
TirbanibulinCytochrome P450 2B6enzyme
TirbanibulinCytochrome P450 2C9enzyme
TirbanibulinCytochrome P450 2C19enzyme
TirbanibulinCytochrome P450 2D6enzyme
TirbanibulinMultidrug and toxin extrusion protein 1transporter
TirbanibulinMultidrug and toxin extrusion protein 2transporter
TirbanibulinSolute carrier organic anion transporter family member 1B1transporter
TirbanibulinSolute carrier organic anion transporter family member 1B3transporter
TirbanibulinSolute carrier family 22 member 1transporter
TirbanibulinSolute carrier family 22 member 2transporter
CetilistatPancreatic triacylglycerol lipasetarget
FosaprepitantCytochrome P450 3A4enzyme
FosaprepitantCytochrome P450 2C9enzyme
ReversineAurora kinase Btarget
ReversineInner centromere proteintarget
OlodaterolBeta-2 adrenergic receptortarget
OlodaterolCytochrome P450 2C9enzyme
OlodaterolCytochrome P450 2C8enzyme
PinaveriumVoltage-dependent L-type calcium channel subunit alpha-1Starget
PinaveriumCytochrome P450 3A4enzyme
ViloxazineSodium-dependent noradrenaline transportertarget
ViloxazineCytochrome P450 1A2enzyme
ViloxazineCytochrome P450 2D6enzyme
ViloxazineUDP-glucuronosyltransferase 1-9enzyme
ViloxazineUDP-glucuronosyltransferase 2B15enzyme
ViloxazineCytochrome P450 2B6enzyme
ViloxazineCytochrome P450 3A4enzyme
ViloxazineCytochrome P450 3A5enzyme
ViloxazineMultidrug and toxin extrusion protein 1transporter
Viloxazine5-hydroxytryptamine receptor 2Btarget
Viloxazine5-hydroxytryptamine receptor 2Ctarget
ViloxazineAlpha-1B adrenergic receptortarget
ViloxazineBeta-2 adrenergic receptortarget
ViloxazineAmine oxidase [flavin-containing] Atarget
ViloxazineAmine oxidase [flavin-containing] Btarget
ViloxazineHistamine H1 receptortarget
ViloxazineHistamine H2 receptortarget
ViloxazineMuscarinic acetylcholine receptor M1target
ViloxazineMuscarinic acetylcholine receptor M2target
ViloxazineMuscarinic acetylcholine receptor M3target
ViloxazineMuscarinic acetylcholine receptor M4target
PholcodineMu-type opioid receptortarget
PholcodineKappa-type opioid receptortarget
PholcodineDelta-type opioid receptortarget
MolsidomineGuanylate cyclase soluble subunit alpha-2target
MolsidomineGuanylate cyclase soluble subunit alpha-2enzyme
MolsidominecGMP-specific 3',5'-cyclic phosphodiesteraseenzyme
PramocaineVoltage-gated sodium channel alpha subunittarget
FostamatinibAdenosine receptor A3target
Fostamatinibvesicular monoamine transporter 2 (VMAT2)target
FostamatinibFatty-acid amide hydrolase 1target
FostamatinibEquilibrative nucleoside transporter 1target
FostamatinibUDP-glucuronosyltransferase 1-1target
FostamatinibcGMP-specific 3',5'-cyclic phosphodiesterasetarget
FostamatinibArachidonate 5-lipoxygenasetarget
FostamatinibCathepsin Starget
FostamatinibCathepsin L1target
FostamatinibTyrosine-protein kinase ABL1target
FostamatinibCalcium-dependent protein kinase 1target
FostamatinibSerine/threonine-protein kinase PknBtarget
FostamatinibRibosomal protein S6 kinase alpha-6target
FostamatinibNon-receptor tyrosine-protein kinase TYK2target
FostamatinibAtypical kinase COQ8A, mitochondrialtarget
FostamatinibTyrosine-protein kinase JAK1target
FostamatinibHepatocyte growth factor receptortarget
FostamatinibSerine/threonine-protein kinase NIM1target
FostamatinibSerine/threonine-protein kinase MST4target
FostamatinibcAMP-dependent protein kinase catalytic subunit alphatarget
FostamatinibSerine/threonine-protein kinase 24target
FostamatinibSerine/threonine-protein kinase 3target
FostamatinibTyrosine-protein kinase Tectarget
FostamatinibTyrosine-protein kinase SYKtarget
FostamatinibSerine/threonine-protein kinase 33target
FostamatinibSerine/threonine-protein kinase 35target
FostamatinibSerine/threonine-protein kinase 36target
FostamatinibSerine/threonine-protein kinase 38target
FostamatinibSerine/threonine-protein kinase 38-liketarget
FostamatinibSTE20/SPS1-related proline-alanine-rich protein kinasetarget
FostamatinibSerine/threonine-protein kinase TAO1target
FostamatinibSerine/threonine-protein kinase TAO2target
FostamatinibSerine/threonine-protein kinase TAO3target
FostamatinibSerine/threonine-protein kinase TBK1target
FostamatinibAngiopoietin-1 receptortarget
FostamatinibDual specificity testis-specific protein kinase 1target
FostamatinibTGF-beta receptor type-1target
FostamatinibTGF-beta receptor type-2target
FostamatinibTyrosine-protein kinase receptor Tie-1target
FostamatinibSerine/threonine-protein kinase tousled-like 1target
FostamatinibSerine/threonine-protein kinase tousled-like 2target
FostamatinibTRAF2 and NCK-interacting protein kinasetarget
FostamatinibNon-receptor tyrosine-protein kinase TNK1target
FostamatinibActivated CDC42 kinase 1target
FostamatinibSerine/threonine-protein kinase TNNI3Ktarget
FostamatinibTestis-specific serine/threonine-protein kinase 1target
FostamatinibDual specificity protein kinase TTKtarget
FostamatinibTyrosine-protein kinase TXKtarget
FostamatinibTyrosine-protein kinase receptor TYRO3target
FostamatinibSerine/threonine-protein kinase ULK1target
FostamatinibSerine/threonine-protein kinase ULK2target
FostamatinibSerine/threonine-protein kinase ULK3target
FostamatinibWee1-like protein kinasetarget
FostamatinibTyrosine-protein kinase Yestarget
FostamatinibMitogen-activated protein kinase kinase kinase 19target
FostamatinibMitogen-activated protein kinase kinase kinase MLTtarget
FostamatinibTyrosine-protein kinase ZAP-70target
FostamatinibAP2-associated protein kinase 1target
FostamatinibAbelson tyrosine-protein kinase 2target
FostamatinibActivin receptor type-1target
FostamatinibActivin receptor type-1Btarget
FostamatinibAtypical kinase COQ8B, mitochondrialtarget
FostamatinibALK tyrosine kinase receptortarget
FostamatinibAnkyrin repeat and protein kinase domain-containing protein 1target
FostamatinibAurora kinase Atarget
FostamatinibAurora kinase Btarget
FostamatinibAurora kinase Ctarget
FostamatinibTyrosine-protein kinase receptor UFOtarget
FostamatinibTyrosine-protein kinase Blktarget
FostamatinibBMP-2-inducible protein kinasetarget
FostamatinibBone morphogenetic protein receptor type-1Btarget
FostamatinibBone morphogenetic protein receptor type-2target
FostamatinibCytoplasmic tyrosine-protein kinase BMXtarget
FostamatinibSerine/threonine-protein kinase B-raftarget
FostamatinibTyrosine-protein kinase BTKtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type 1target
FostamatinibCalcium/calmodulin-dependent protein kinase type 1Dtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type 1Gtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit alphatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit betatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit deltatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit gammatarget
FostamatinibCalcium/calmodulin-dependent protein kinase kinase 1target
FostamatinibCalcium/calmodulin-dependent protein kinase kinase 2target
FostamatinibPeripheral plasma membrane protein CASKtarget
FostamatinibKappa-caseintarget
FostamatinibCyclin-dependent kinase 1target
FostamatinibSerine/threonine-protein kinase MRCK gammatarget
FostamatinibCyclin-dependent kinase 4target
FostamatinibCyclin-dependent kinase-like 1target
FostamatinibCyclin-dependent kinase-like 2target
FostamatinibSerine/threonine-protein kinase Chk1target
FostamatinibSerine/threonine-protein kinase Chk2target
FostamatinibCitron Rho-interacting kinasetarget
FostamatinibDual specificity protein kinase CLK1target
FostamatinibDual specificity protein kinase CLK2target
FostamatinibDual specificity protein kinase CLK3target
FostamatinibDual specificity protein kinase CLK4target
FostamatinibMacrophage colony-stimulating factor 1 receptortarget
FostamatinibTyrosine-protein kinase CSKtarget
FostamatinibCasein kinase I isoform alphatarget
FostamatinibCasein kinase II subunit alphatarget
FostamatinibCasein kinase II subunit alpha'target
FostamatinibDeath-associated protein kinase 1target
FostamatinibDeath-associated protein kinase 2target
FostamatinibDeath-associated protein kinase 3target
FostamatinibSerine/threonine-protein kinase DCLK1target
FostamatinibSerine/threonine-protein kinase DCLK2target
FostamatinibSerine/threonine-protein kinase DCLK3target
FostamatinibEpithelial discoidin domain-containing receptor 1target
FostamatinibDiscoidin domain-containing receptor 2target
FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1Atarget
FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1Btarget
FostamatinibEpidermal growth factor receptortarget
FostamatinibEukaryotic translation initiation factor 2-alpha kinase 1target
FostamatinibInterferon-induced, double-stranded RNA-activated protein kinasetarget
FostamatinibeIF-2-alpha kinase GCN2target
FostamatinibEphrin type-A receptor 1target
FostamatinibEphrin type-A receptor 2target
FostamatinibEphrin type-A receptor 3target
FostamatinibEphrin type-A receptor 4target
FostamatinibEphrin type-A receptor 5target
FostamatinibEphrin type-A receptor 6target
FostamatinibEphrin type-A receptor 7target
FostamatinibEphrin type-A receptor 8target
FostamatinibEphrin type-B receptor 1target
FostamatinibEphrin type-B receptor 2target
FostamatinibEphrin type-B receptor 4target
FostamatinibEphrin type-B receptor 6target
FostamatinibReceptor tyrosine-protein kinase erbB-2target
FostamatinibReceptor tyrosine-protein kinase erbB-4target
FostamatinibSerine/threonine-protein kinase/endoribonuclease IRE1target
FostamatinibTyrosine-protein kinase Fertarget
FostamatinibTyrosine-protein kinase Fes/Fpstarget
FostamatinibFibroblast growth factor receptor 1target
FostamatinibFibroblast growth factor receptor 2target
FostamatinibFibroblast growth factor receptor 3target
FostamatinibTyrosine-protein kinase Fgrtarget
FostamatinibVascular endothelial growth factor receptor 1target
FostamatinibReceptor-type tyrosine-protein kinase FLT3target
FostamatinibVascular endothelial growth factor receptor 3target
FostamatinibSerine/threonine-protein kinase mTORtarget
FostamatinibTyrosine-protein kinase FRKtarget
FostamatinibTyrosine-protein kinase Fyntarget
FostamatinibCyclin-G-associated kinasetarget
FostamatinibGlycogen synthase kinase-3 alphatarget
FostamatinibGlycogen synthase kinase-3 betatarget
FostamatinibTyrosine-protein kinase HCKtarget
FostamatinibHomeodomain-interacting protein kinase 2target
FostamatinibHomeodomain-interacting protein kinase 3target
FostamatinibSerine/threonine-protein kinase ICKtarget
FostamatinibInhibitor of nuclear factor kappa-B kinase subunit betatarget
FostamatinibInhibitor of nuclear factor kappa-B kinase subunit epsilontarget
FostamatinibInsulin receptortarget
FostamatinibInsulin receptor-related proteintarget
FostamatinibInterleukin-1 receptor-associated kinase 1target
FostamatinibInterleukin-1 receptor-associated kinase 3target
FostamatinibInterleukin-1 receptor-associated kinase 4target
FostamatinibTyrosine-protein kinase ITK/TSKtarget
FostamatinibTyrosine-protein kinase JAK2target
FostamatinibTyrosine-protein kinase JAK3target
FostamatinibVascular endothelial growth factor receptor 2target
FostamatinibSerine/threonine-protein kinase SIK3target
FostamatinibMast/stem cell growth factor receptor Kittarget
FostamatinibSerine/threonine-protein kinase LATS1target
FostamatinibTyrosine-protein kinase Lcktarget
FostamatinibLIM domain kinase 1target
FostamatinibLIM domain kinase 2target
FostamatinibLeucine-rich repeat serine/threonine-protein kinase 2target
FostamatinibLeukocyte tyrosine kinase receptortarget
FostamatinibTyrosine-protein kinase Lyntarget
FostamatinibDual specificity mitogen-activated protein kinase kinase 2target
FostamatinibDual specificity mitogen-activated protein kinase kinase 3target
FostamatinibDual specificity mitogen-activated protein kinase kinase 5target
FostamatinibDual specificity mitogen-activated protein kinase kinase 6target
FostamatinibMitogen-activated protein kinase kinase kinase 1target
FostamatinibMitogen-activated protein kinase kinase kinase 10target
FostamatinibMitogen-activated protein kinase kinase kinase 11target
FostamatinibMitogen-activated protein kinase kinase kinase 12target
FostamatinibMitogen-activated protein kinase kinase kinase 13target
FostamatinibMitogen-activated protein kinase kinase kinase 15target
FostamatinibMitogen-activated protein kinase kinase kinase 2target
FostamatinibMitogen-activated protein kinase kinase kinase 3target
FostamatinibMitogen-activated protein kinase kinase kinase 4target
FostamatinibMitogen-activated protein kinase kinase kinase 6target
FostamatinibMitogen-activated protein kinase kinase kinase 9target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 1target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 2target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 3target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 4target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 5target
FostamatinibMitogen-activated protein kinase 10target
FostamatinibMitogen-activated protein kinase 13target
FostamatinibMitogen-activated protein kinase 14target
FostamatinibMitogen-activated protein kinase 15target
FostamatinibMitogen-activated protein kinase 4target
FostamatinibMitogen-activated protein kinase 7target
FostamatinibMitogen-activated protein kinase 9target
FostamatinibMAP kinase-activated protein kinase 5target
FostamatinibSerine/threonine-protein kinase MARK1target
FostamatinibSerine/threonine-protein kinase MARK2target
FostamatinibMAP/microtubule affinity-regulating kinase 3target
FostamatinibMAP/microtubule affinity-regulating kinase 4target
FostamatinibCLIP-associating protein 1target
FostamatinibMicrotubule-associated serine/threonine-protein kinase 1target
FostamatinibMegakaryocyte-associated tyrosine-protein kinasetarget
FostamatinibMaternal embryonic leucine zipper kinasetarget
FostamatinibTyrosine-protein kinase Mertarget
FostamatinibMisshapen-like kinase 1target
FostamatinibMAP kinase-interacting serine/threonine-protein kinase 1target
FostamatinibMAP kinase-interacting serine/threonine-protein kinase 2target
FostamatinibMacrophage-stimulating protein receptortarget
FostamatinibMuscle, skeletal receptor tyrosine-protein kinasetarget
FostamatinibMyosin light chain kinase, smooth muscletarget
FostamatinibMyosin light chain kinase 2, skeletal/cardiac muscletarget
FostamatinibMyosin light chain kinase 3target
FostamatinibMyosin light chain kinase family member 4target
FostamatinibMyosin-IIIatarget
FostamatinibSerine/threonine-protein kinase Nek1target
FostamatinibSerine/threonine-protein kinase Nek11target
FostamatinibSerine/threonine-protein kinase Nek2target
FostamatinibSerine/threonine-protein kinase Nek3target
FostamatinibSerine/threonine-protein kinase Nek4target
FostamatinibSerine/threonine-protein kinase Nek5target
FostamatinibSerine/threonine-protein kinase Nek9target
FostamatinibHigh affinity nerve growth factor receptortarget
FostamatinibBDNF/NT-3 growth factors receptortarget
FostamatinibNT-3 growth factor receptortarget
FostamatinibNUAK family SNF1-like kinase 1target
FostamatinibNUAK family SNF1-like kinase 2target
FostamatinibSerine/threonine-protein kinase OSR1target
FostamatinibSerine/threonine-protein kinase PAK 1target
FostamatinibSerine/threonine-protein kinase PAK 2target
FostamatinibSerine/threonine-protein kinase PAK 3target
FostamatinibSerine/threonine-protein kinase PAK 4target
FostamatinibSerine/threonine-protein kinase PAK 6target
FostamatinibSerine/threonine-protein kinase PAK 5target
FostamatinibCyclin-dependent kinase 16target
FostamatinibCyclin-dependent kinase 17target
FostamatinibPlatelet-derived growth factor receptor alphatarget
FostamatinibPlatelet-derived growth factor receptor betatarget
Fostamatinib3-phosphoinositide-dependent protein kinase 1target
FostamatinibCyclin-dependent kinase 15target
FostamatinibPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformtarget
FostamatinibPhosphatidylinositol 4-kinase betatarget
FostamatinibPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betatarget
FostamatinibPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammatarget
FostamatinibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
FostamatinibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
FostamatinibSerine/threonine-protein kinase pim-1target
FostamatinibSerine/threonine-protein kinase pim-3target
FostamatinibPhosphatidylinositol 5-phosphate 4-kinase type-2 betatarget
FostamatinibPhosphatidylinositol 5-phosphate 4-kinase type-2 gammatarget
FostamatinibMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinasetarget
FostamatinibSerine/threonine-protein kinase N1target
FostamatinibSerine/threonine-protein kinase N2target
FostamatinibSerine/threonine-protein kinase PLK1target
FostamatinibSerine/threonine-protein kinase PLK2target
FostamatinibSerine/threonine-protein kinase PLK3target
FostamatinibSerine/threonine-protein kinase PLK4target
Fostamatinib5'-AMP-activated protein kinase catalytic subunit alpha-1target
Fostamatinib5'-AMP-activated protein kinasetarget
FostamatinibcAMP-dependent protein kinase catalytic subunit betatarget
FostamatinibProtein kinase C delta typetarget
FostamatinibProtein kinase C epsilon typetarget
FostamatinibProtein kinase C gamma type (PRKCG)target
FostamatinibProtein kinase C iota typetarget
FostamatinibProtein kinase C theta typetarget
FostamatinibSerine/threonine-protein kinase D1target
FostamatinibcGMP-dependent protein kinase 2target
FostamatinibSerine/threonine-protein kinase PRP4 homologtarget
FostamatinibFocal adhesion kinase 1target
FostamatinibProtein-tyrosine kinase 2-betatarget
FostamatinibProtein-tyrosine kinase 6target
FostamatinibRAF proto-oncogene serine/threonine-protein kinasetarget
FostamatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
FostamatinibSerine/threonine-protein kinase RIO1target
FostamatinibSerine/threonine-protein kinase RIO2target
FostamatinibSerine/threonine-protein kinase RIO3target
FostamatinibReceptor-interacting serine/threonine-protein kinase 1target
FostamatinibReceptor-interacting serine/threonine-protein kinase 2target
FostamatinibReceptor-interacting serine/threonine-protein kinase 4target
FostamatinibRho-associated protein kinase 2target
FostamatinibProto-oncogene tyrosine-protein kinase ROStarget
FostamatinibRibosomal protein S6 kinase alpha-1target
FostamatinibRibosomal protein S6 kinase alpha-3target
FostamatinibSerine/threonine-protein kinase SBK1target
FostamatinibUncharacterized serine/threonine-protein kinase SBK3target
FostamatinibSerine/threonine-protein kinase Sgk3target
FostamatinibSerine/threonine-protein kinase SIK1target
FostamatinibSerine/threonine-protein kinase SIK2target
FostamatinibSTE20-like serine/threonine-protein kinasetarget
FostamatinibSNF-related serine/threonine-protein kinasetarget
FostamatinibProto-oncogene tyrosine-protein kinase Srctarget
FostamatinibTyrosine-protein kinase Srmstarget
FostamatinibSerine/threonine-protein kinase 10target
FostamatinibSerine/threonine-protein kinase 16target
FostamatinibSerine/threonine-protein kinase 17Atarget
FostamatinibSerine/threonine-protein kinase 17Btarget
FostamatinibSerine/threonine-protein kinase 32Atarget
FostamatinibCytochrome P450 3A4enzyme
FostamatinibATP-binding cassette sub-family G member 2transporter
FostamatinibATP-binding cassette sub-family B member 5transporter
FostamatinibUDP-glucuronosyltransferase 1-9enzyme
LandiololCytochrome P450 2D6enzyme
TazemetostatHistone-lysine N-methyltransferase EZH2target
TazemetostatP-glycoprotein 1transporter
TazemetostatMultidrug and toxin extrusion protein 1transporter
TazemetostatMultidrug and toxin extrusion protein 2transporter
TazemetostatCytochrome P450 3A Subfamilyenzyme
TazemetostatHistone-lysine N-methyltransferase EZH1target
TazemetostatATP-binding cassette sub-family G member 2transporter
TazemetostatCytochrome P450 3A4enzyme
XamoterolBeta-1 adrenergic receptortarget
WIN 55212-2Cytochrome P450 3A4enzyme
Baloxavir marboxilATP-binding cassette sub-family B member 5transporter
Baloxavir marboxilUDP-glucuronosyltransferase 1-3enzyme
Baloxavir marboxilCytochrome P450 3A4enzyme
Baloxavir marboxilPolymerase acidic proteintarget
CeralasertibSerine/threonine-protein kinase ATRtarget
PemigatinibCytochrome P450 3A4enzyme
PemigatinibFibroblast growth factor receptor 1target
PemigatinibFibroblast growth factor receptor 2target
PemigatinibFibroblast growth factor receptor 3target
PemigatinibFibroblast growth factor receptor 4target
PemigatinibP-glycoprotein 1transporter
PemigatinibATP-binding cassette sub-family G member 2transporter
PemigatinibSolute carrier family 22 member 2transporter
PemigatinibMultidrug and toxin extrusion protein 1transporter