Phenylacetates

Name
Phenylacetates
Accession Number
DBCAT000845
Description

Derivatives of phenylacetic acid. Included under this heading are a variety of acid forms, salts, esters, and amides that contain the benzeneacetic acid structure. Note that this class of compounds should not be confused with derivatives of phenyl acetate, which contain the PHENOL ester of ACETIC ACID.

Drugs
DrugDrug Description
AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
AdiphenineNot Annotated
BenactyzineBenactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. Benactyzine is no longer widely used in medicine, although it is still a...
BevoniumNot Annotated
ClidiniumA synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS.
CyclopentolateAn anticholinergic used to cause mydriasis and cycloplegia for diagnostic testing.
DenaverineDenaverine is a small molecule drug. The usage of the INN stem '-verine' in the name indicates that Denaverine is a spasmolytic with a papaverine-like action. Denaverine has a monoisotopic...
DexmethylphenidateA norepinephrine-dopamine reuptake inhibitor used in the treatment of ADHD in conjunction with other therapies.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Diclofenac etalhyaluronateDiclofenac etalhyaluronate is a small molecule drug. The usage of the INN stem '-ac' in the name indicates that Diclofenac etalhyaluronate is a anti-inflammatory agent, ibufenac derivative. Diclofenac etalhyaluronate has...
DifemerineNot Annotated
DimenoxadolDimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United...
Diphenylacetic acidNot Available
Homogentisic acidNot Available
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
MepenzolateA postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued.
MethylphenidateA stimulant used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
PF-03635659Pf03635659 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
PiperidolateNot Annotated
PoldineNot Annotated
PropanididAn intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)
PropiverineAn antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
SerdexmethylphenidateA prodrug of the CNS stimulant dexmethylphenidate used as a first-line treatment for Attention Deficit Hyperactivity Disorder (ADHD).
TiphenamilNot Annotated
TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
Drugs & Drug Targets
DrugTargetType
AceclofenacProstaglandin G/H synthase 1target
AceclofenacProstaglandin G/H synthase 2target
AceclofenacCytochrome P450 2C9enzyme
AdiphenineMuscle nicotinic acetylcholine receptortarget
AdiphenineNeuronal Acetylcholine (nACh) Receptor Subunitstarget
BenactyzineMuscarinic acetylcholine receptor M5target
ClidiniumMuscarinic acetylcholine receptor M3target
ClidiniumMuscarinic acetylcholine receptor M1target
CyclopentolateMuscarinic acetylcholine receptor M3target
CyclopentolateMuscarinic acetylcholine receptor M5target
CyclopentolateCholinesteraseenzyme
CyclopentolateMuscarinic acetylcholine receptor M1target
DexmethylphenidateCarboxylesteraseenzyme
DexmethylphenidateSodium-dependent serotonin transportertarget
DexmethylphenidateSodium-dependent noradrenaline transportertarget
DexmethylphenidateSodium-dependent dopamine transportertarget
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1A3enzyme
DiclofenacUDP-glucuronosyltransferase 1A9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacPolyunsaturated fatty acid 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacATP-dependent translocase ABCB1transporter
DiclofenacHuman Cyclooxygenasestarget
DiclofenacCytochrome P450 3A4enzyme
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacOrganic anion transporter 3transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacATP-binding cassette sub-family C member 1transporter
DiclofenacATP-binding cassette sub-family C member 4transporter
DiclofenacCytochrome P450 2C8enzyme
DiclofenacProstaglandin G/H synthase 2target
DiclofenacProstaglandin G/H synthase 1target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacAlbumincarrier
Diphenylacetic acidCathepsin Btarget
Homogentisic acidPenicillin G acylasetarget
LumiracoxibCytochrome P450 1A2enzyme
LumiracoxibUDP-glucuronosyltransferase 1A9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibProstaglandin G/H synthase 2target
MepenzolateMuscarinic acetylcholine receptor M3target
MepenzolateMuscarinic acetylcholine receptor M1target
MepenzolateMuscarinic acetylcholine receptor M5target
MethylphenidateSodium-dependent noradrenaline transportertarget
Methylphenidate5-hydroxytryptamine receptor 1Atarget
MethylphenidateCarboxylesteraseenzyme
MethylphenidateSodium-dependent dopamine transportertarget
PF-03635659Muscarinic acetylcholine receptor M3target
PropanididAcetylcholinesterasetarget
PropanididCholinesterasetarget
PropiverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
PropiverineAlpha-1A adrenergic receptortarget
PropiverineCytochrome P450 3A4enzyme
PropiverineFlavin-containing monooxygenase 1enzyme
PropiverineMuscarinic acetylcholine receptor M5target
PropiverineFlavin-containing monooxygenase 3enzyme
PropiverineMuscarinic acetylcholine receptor M1target
PropiverineMuscarinic acetylcholine receptor M2target
PropiverineMuscarinic acetylcholine receptor M3target
PropiverineMuscarinic acetylcholine receptor M4target
SerdexmethylphenidateSodium-dependent noradrenaline transportertarget
SerdexmethylphenidateCarboxylesteraseenzyme
Serdexmethylphenidate5-hydroxytryptamine receptor 1Atarget
SerdexmethylphenidateSodium-dependent dopamine transportertarget
TrospiumMuscarinic acetylcholine receptor M5target
TrospiumMuscarinic acetylcholine receptor M3target
TrospiumCytochrome P450 2D6enzyme
TrospiumMuscarinic acetylcholine receptor M2target
TrospiumMuscarinic acetylcholine receptor M1target