Accession Number

Androstanes and androstane derivatives which are substituted in any position with one or more hydroxyl groups.

DrugDrug Description
OxandroloneAn androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis.
PancuroniumA neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
VecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures.
StanoloneA potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure...
OxymetholoneAn anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias.
StanozololAn anabolic steroid used to manage hereditary angioedema.
RocuroniumA vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery.
5alpha-androstane-3beta,17alpha-diol5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite of testosterone with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
TrilostaneUsed in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
RapacuroniumA nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures.
16-BromoepiandrosteroneInvestigated for use/treatment in cystic fibrosis, HIV infection, hepatitis (viral, B), and malaria.
IstaroximeInvestigated for use/treatment in heart disease.
MesteroloneAn anabolic steroid indicated in the treatment of low testosterone, hypogonadism, oligozoospermia, and Leydig cell failure.
Drugs & Drug Targets
OxandroloneAndrogen receptortarget
OxandroloneCytochrome P450 2C9enzyme
PancuroniumNeuronal acetylcholine receptor subunit alpha-2target
PancuroniumMuscarinic acetylcholine receptor M2target
PancuroniumMuscarinic acetylcholine receptor M3target
PancuroniumSolute carrier family 22 member 1transporter
PancuroniumSolute carrier family 22 member 2transporter
VecuroniumP-glycoprotein 1transporter
VecuroniumNeuronal acetylcholine receptor subunit alpha-2target
StanoloneSex hormone-binding globulincarrier
StanoloneAndrogen receptortarget
StanoloneEstradiol 17-beta-dehydrogenase 1target
StanoloneP-glycoprotein 1transporter
StanoloneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
StanoloneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
StanoloneCytochrome P450 19A1enzyme
StanoloneEstrogen receptor alphatarget
StanoloneMineralocorticoid receptortarget
StanoloneAldo-keto reductase family 1 member C3enzyme
OxymetholoneAndrogen receptortarget
OxymetholoneSerum albumincarrier
OxymetholoneSex hormone-binding globulincarrier
OxymetholoneNatriuretic peptides Btarget
OxymetholoneAmine oxidase [flavin-containing] Aenzyme
OxymetholoneCytochrome P450 2D6enzyme
Oxymetholone3-oxo-5-alpha-steroid 4-dehydrogenase 1enzyme
OxymetholoneCytochrome P450 3A4enzyme
OxymetholoneCytochrome P450 3A5enzyme
OxymetholoneCytochrome P450 3A7enzyme
OxymetholoneCytochrome P450 3A43enzyme
StanozololGlucocorticoid binding proteinstarget
StanozololAndrogen receptortarget
RocuroniumNeuronal acetylcholine receptor subunit alpha-2target
RocuroniumMuscarinic acetylcholine receptor M2target
Rocuronium5-hydroxytryptamine receptor 3Atarget
RocuroniumSolute carrier family 22 member 1transporter
RocuroniumSolute carrier organic anion transporter family member 1A2transporter
5alpha-androstane-3beta,17alpha-diolSex hormone-binding globulincarrier
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2target
TrilostaneEstrogen receptor betatarget
TrilostaneEstrogen receptor alphatarget
RapacuroniumMuscarinic acetylcholine receptor M2target
16-BromoepiandrosteroneGlucose-6-phosphate 1-dehydrogenasetarget
IstaroximeSarcoplasmic/endoplasmic reticulum calcium ATPase 2target
IstaroximeSodium/potassium-transporting ATPase subunit alpha-1target