Name
Androgens
Accession Number
DBCAT001011
Description

Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.

ATC Classification
Drugs
DrugDrug Description
TestosteroneA hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause.
StanoloneA potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure...
FluoxymesteroneA synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women.
Testosterone propionateA slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles.
DanazolA synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts.
Testosterone cypionateAn androgen used to treat low or absent testosterone.
Testosterone enanthateAn androgen used to treat low or absent testosterone.
Testosterone undecanoateAn androgen used to treat low or absent testosterone.
OxandroloneAn androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis.
OxymetholoneAn anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias.
StanozololAn anabolic steroid used to manage hereditary angioedema.
GLPG-0492Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of GLPG0492).
NandroloneAn anabolic steroid indicated to increase bone density and muscle mass in patients with osteoporosis.
MesteroloneAn anabolic steroid indicated in the treatment of low testosterone, hypogonadism, oligozoospermia, and Leydig cell failure.
MethyltestosteroneA synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females.
Nandrolone decanoateAn anabolic steroid indicated for the management of the anemia of renal insufficiency by increasing hemoglobin and red cell mass.
Nandrolone phenpropionateFor the treatment of refractory deficient red cell production anemias, breast carcinoma, hereditary angioedema, antithrombin III deficiency, fibrinogen excess, growth failure and Turner's syndrome. It is also indicated in the...
TetrahydrogestrinoneNot Available
Drugs & Drug Targets
DrugTargetType
TestosteroneAndrogen receptortarget
TestosteroneCytochrome P450 3A4enzyme
TestosteroneCytochrome P450 19A1enzyme
TestosteroneAmine oxidase [flavin-containing] Aenzyme
TestosteroneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
TestosteroneSerum albumincarrier
TestosteroneSex hormone-binding globulincarrier
TestosteroneCytochrome P450 3A5enzyme
TestosteroneCytochrome P450 3A7enzyme
TestosteroneSolute carrier family 22 member 8transporter
TestosteroneSolute carrier family 22 member 7transporter
TestosteroneSodium/bile acid cotransportertransporter
TestosteroneATP-binding cassette sub-family G member 2transporter
TestosteroneCytochrome P450 1A1enzyme
TestosteroneCytochrome P450 1B1enzyme
TestosteroneCytochrome P450 2A13enzyme
TestosteroneCytochrome P450 2B6enzyme
TestosteroneCytochrome P450 2C19enzyme
TestosteroneCytochrome P450 2C8enzyme
TestosteroneCytochrome P450 2C9enzyme
TestosteroneCytochrome P450 3A43enzyme
TestosteroneEstrogen receptor alphatarget
TestosteroneMineralocorticoid receptortarget
TestosteroneSolute carrier organic anion transporter family member 1B3transporter
StanoloneSex hormone-binding globulincarrier
StanoloneAndrogen receptortarget
StanoloneEstradiol 17-beta-dehydrogenase 1target
StanoloneP-glycoprotein 1transporter
StanoloneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
StanoloneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
StanoloneCytochrome P450 19A1enzyme
StanoloneEstrogen receptor alphatarget
StanoloneMineralocorticoid receptortarget
FluoxymesteroneSex hormone-binding globulincarrier
FluoxymesteroneEstrogen receptor alphatarget
FluoxymesteroneAndrogen receptortarget
FluoxymesteroneGlucocorticoid receptortarget
FluoxymesteroneCorticosteroid 11-beta-dehydrogenase isozyme 2target
Testosterone propionateAndrogen receptortarget
Testosterone propionateCatechol O-methyltransferaseenzyme
Testosterone propionateUDP-glucuronosyltransferase 1-1enzyme
Testosterone propionate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
Testosterone propionateCytochrome P450 3A4enzyme
Testosterone propionateP-glycoprotein 1transporter
Testosterone propionateSex hormone-binding globulincarrier
Testosterone propionateSerum albumincarrier
DanazolEstrogen receptor alphatarget
DanazolGonadotropin-releasing hormone receptortarget
DanazolPutative gonadotropin-releasing hormone II receptortarget
DanazolSex hormone-binding globulincarrier
DanazolC-C motif chemokine 2target
DanazolCytochrome P450 19A1enzyme
DanazolAndrogen receptortarget
DanazolProgesterone receptortarget
DanazolCytochrome P450 3A4enzyme
Testosterone cypionateAndrogen receptortarget
Testosterone cypionateCytochrome P450 3A4enzyme
Testosterone cypionateAmine oxidase [flavin-containing] Aenzyme
Testosterone cypionateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
Testosterone cypionateSerum albumincarrier
Testosterone cypionateSex hormone-binding globulincarrier
Testosterone cypionateCytochrome P450 3A5enzyme
Testosterone cypionateCytochrome P450 3A7enzyme
Testosterone cypionateSolute carrier organic anion transporter family member 1A2transporter
Testosterone cypionateSolute carrier family 22 member 8transporter
Testosterone cypionateSolute carrier family 22 member 7transporter
Testosterone cypionateP-glycoprotein 1transporter
Testosterone cypionateSodium/bile acid cotransportertransporter
Testosterone cypionateSolute carrier family 22 member 3transporter
Testosterone cypionateSolute carrier family 22 member 4transporter
Testosterone cypionateATP-binding cassette sub-family G member 2transporter
Testosterone cypionateCytochrome P450 1A1enzyme
Testosterone cypionateCytochrome P450 2A13enzyme
Testosterone cypionateCytochrome P450 2B6enzyme
Testosterone cypionateCytochrome P450 2C19enzyme
Testosterone cypionateCytochrome P450 2C8enzyme
Testosterone cypionateCytochrome P450 2C9enzyme
Testosterone cypionateCytochrome P450 3A43enzyme
Testosterone cypionateEstrogen receptor alphatarget
Testosterone cypionateMineralocorticoid receptortarget
Testosterone cypionate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
Testosterone cypionateCytochrome P450 19A1enzyme
Testosterone enanthateAndrogen receptortarget
Testosterone enanthateCytochrome P450 3A4enzyme
Testosterone enanthateAmine oxidase [flavin-containing] Aenzyme
Testosterone enanthateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
Testosterone enanthateSerum albumincarrier
Testosterone enanthateSex hormone-binding globulincarrier
Testosterone enanthateCytochrome P450 3A5enzyme
Testosterone enanthateCytochrome P450 3A7enzyme
Testosterone enanthateSolute carrier organic anion transporter family member 1A2transporter
Testosterone enanthateSolute carrier family 22 member 8transporter
Testosterone enanthateSolute carrier family 22 member 7transporter
Testosterone enanthateP-glycoprotein 1transporter
Testosterone enanthateSodium/bile acid cotransportertransporter
Testosterone enanthateSolute carrier family 22 member 3transporter
Testosterone enanthateSolute carrier family 22 member 4transporter
Testosterone enanthateATP-binding cassette sub-family G member 2transporter
Testosterone enanthateCytochrome P450 1A1enzyme
Testosterone enanthateCytochrome P450 2A13enzyme
Testosterone enanthateCytochrome P450 2B6enzyme
Testosterone enanthateCytochrome P450 2C19enzyme
Testosterone enanthateCytochrome P450 2C8enzyme
Testosterone enanthateCytochrome P450 2C9enzyme
Testosterone enanthateCytochrome P450 3A43enzyme
Testosterone enanthateEstrogen receptor alphatarget
Testosterone enanthateMineralocorticoid receptortarget
Testosterone enanthate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
Testosterone enanthateCytochrome P450 19A1enzyme
Testosterone undecanoateAndrogen receptortarget
Testosterone undecanoateCytochrome P450 3A4enzyme
Testosterone undecanoateAmine oxidase [flavin-containing] Aenzyme
Testosterone undecanoateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
Testosterone undecanoateSerum albumincarrier
Testosterone undecanoateSex hormone-binding globulincarrier
Testosterone undecanoateCytochrome P450 3A5enzyme
Testosterone undecanoateCytochrome P450 3A7enzyme
Testosterone undecanoateSolute carrier organic anion transporter family member 1A2transporter
Testosterone undecanoateSolute carrier family 22 member 8transporter
Testosterone undecanoateSolute carrier family 22 member 7transporter
Testosterone undecanoateP-glycoprotein 1transporter
Testosterone undecanoateSodium/bile acid cotransportertransporter
Testosterone undecanoateSolute carrier family 22 member 4transporter
Testosterone undecanoateATP-binding cassette sub-family G member 2transporter
Testosterone undecanoateCytochrome P450 1A1enzyme
Testosterone undecanoateCytochrome P450 1B1enzyme
Testosterone undecanoateCytochrome P450 2A13enzyme
Testosterone undecanoateCytochrome P450 2B6enzyme
Testosterone undecanoateCytochrome P450 2C19enzyme
Testosterone undecanoateCytochrome P450 2C8enzyme
Testosterone undecanoateCytochrome P450 2C9enzyme
Testosterone undecanoateCytochrome P450 3A43enzyme
Testosterone undecanoateEstrogen receptor alphatarget
Testosterone undecanoateMineralocorticoid receptortarget
Testosterone undecanoate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
Testosterone undecanoateSolute carrier family 22 member 2transporter
Testosterone undecanoateMultidrug and toxin extrusion protein 1transporter
Testosterone undecanoateSolute carrier organic anion transporter family member 1B3transporter
Testosterone undecanoateCytochrome P450 19A1enzyme
OxandroloneAndrogen receptortarget
OxandroloneCytochrome P450 2C9enzyme
OxymetholoneAndrogen receptortarget
OxymetholoneSerum albumincarrier
OxymetholoneSex hormone-binding globulincarrier
OxymetholoneNatriuretic peptides Btarget
OxymetholoneAmine oxidase [flavin-containing] Aenzyme
OxymetholoneCytochrome P450 2D6enzyme
Oxymetholone3-oxo-5-alpha-steroid 4-dehydrogenase 1enzyme
OxymetholoneCytochrome P450 3A4enzyme
OxymetholoneCytochrome P450 3A5enzyme
OxymetholoneCytochrome P450 3A7enzyme
OxymetholoneCytochrome P450 3A43enzyme
StanozololGlucocorticoid binding proteinstarget
StanozololAndrogen receptortarget
MethyltestosteroneCytochrome P450 2B6enzyme
MethyltestosteroneCytochrome P450 3A4enzyme
MethyltestosteroneAndrogen receptortarget
MethyltestosteroneSolute carrier organic anion transporter family member 1A2transporter
MethyltestosteroneSolute carrier family 22 member 8transporter
MethyltestosteroneSerum albumincarrier
MethyltestosteroneSex hormone-binding globulincarrier
MethyltestosteroneEstrogen receptor alphatarget
MethyltestosteroneCytochrome P450 19A1enzyme
Nandrolone decanoateAndrogen receptortarget
Nandrolone decanoateCytochrome P450 19A1enzyme
Nandrolone decanoateAmine oxidase [flavin-containing] Benzyme
Nandrolone decanoateAmine oxidase [flavin-containing] Aenzyme
Nandrolone decanoateProto-oncogene c-Fostarget
Nandrolone decanoate5-hydroxytryptamine 2 receptortarget
Nandrolone decanoate5-hydroxytryptamine receptor 1Btarget
Nandrolone decanoateInsulin-like growth factor 1 receptortarget
Nandrolone decanoateDopamine receptortarget
Nandrolone decanoateUDP-glucuronosyltransferase 2B7enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 1-4enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 2B4enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 1-3enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 1-1enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 1-10enzyme
Nandrolone decanoateSex hormone-binding globulincarrier
Nandrolone phenpropionateAndrogen receptortarget
TetrahydrogestrinoneAndrogen receptortarget