Monoterpenes

Name
Monoterpenes
Accession Number
DBCAT001046
Description

Compounds with a core of 10 carbons generally formed via the mevalonate pathway from the combination of 3,3-dimethylallyl pyrophosphate and isopentenyl pyrophosphate. They are cyclized and oxidized in a variety of ways. Due to the low molecular weight many of them exist in the form of essential oils (OILS, VOLATILE).

Drugs
DrugDrug Description
CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
ThymolAn essential oil found in various over-the-counter antibacterial and antifungal products.
Pyrethrum extractA chrysanthemum flower extract used to treat head, pubic, and body lice.
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
MentholNot Annotated
(4R)-limoneneLimonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to...
ThiocamphorNot Available
CamphaneNot Available
PermethrinAn insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
DeramciclaneInvestigated for use/treatment in anxiety disorders.
BlinatumomabAn antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
EcamsuleA sunscreen agent found in sunscreens that absorbs UV rays.
EnzacameneAn ingredient used in sunscreen to block UVB radiation.
BorneolNot Annotated
Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
DeltamethrinNot Annotated
XibornolA lipophilic antiseptic indicated as an adjunct in the treatment of susceptible oral infections.
PhenothrinA pyrethroid indicated in the treatment of head lice.
CypermethrinA medication used to treat parasitic skin diseases.
BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
TetramethrinNot Annotated
CyfluthrinNot Annotated
GeraniolGeraniol is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
Bornyl acetateNot Annotated
BifenthrinBifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry).
alpha-PineneA mono-terpene indicated in combination with other plant-derived compounds for the treatment of bladder, kidney, and urinary stones.
beta-PineneA mono-terpene indicated in combination with other plant-derived compounds for the treatment of bladder, kidney, and urinary stones.
CarvaseptA medication used to treat hemorrhoids, anal fissures, and pruritus ani.
CampheneAn excipient in medications for flavouring.
FenchoneAn ingredient used in medication to treat kidney, bladder, and urinary tract stones.
MenthoneA medication used to treat stone formation in the gallbladder and liver.
VerbenoneNot Annotated
CarvacrolNot Annotated
Thyme oilNot Annotated
Drugs & Drug Targets
DrugTargetType
CamphorCamphor 5-monooxygenasetarget
CamphorTransient receptor potential cation channel subfamily V member 1target
CamphorTransient receptor potential cation channel subfamily V member 3target
CamphorTransient receptor potential cation channel subfamily A member 1target
CamphorTransient receptor potential cation channel subfamily M member 8target
Pyrethrum extractNuclear receptor subfamily 1 group I member 2target
MentholTransient receptor potential cation channel subfamily M member 8target
ThiocamphorCamphor 5-monooxygenasetarget
CamphaneCamphor 5-monooxygenasetarget
PermethrinCytochrome P450 2B6enzyme
PermethrinSodium channel protein type 1 subunit alphatarget
PermethrinEstrogen receptor alphatarget
PermethrinNuclear receptor subfamily 1 group I member 2target
Deramciclane5-hydroxytryptamine receptor 2Atarget
Deramciclane5-hydroxytryptamine receptor 2Ctarget
DeramciclaneCytochrome P450 2D6enzyme
BlinatumomabB-lymphocyte antigen CD19target
BlinatumomabT-cell surface glycoprotein CD3 delta chaintarget
EnzacameneProgesterone receptortarget
EnzacameneAndrogen receptortarget
EnzacameneEstrogen receptor betatarget
EnzacameneEstrogen receptor alphatarget
BioallethrinVoltage-gated sodium channel alpha subunittarget
BioallethrinSodium channel proteintarget
BioallethrinVoltage-dependent calcium channeltarget
BioallethrinVoltage-dependent T-type calcium channeltarget
BioallethrinVoltage-dependent P/Q-type calcium channeltarget
BioallethrinVoltage-dependent L-type calcium channeltarget
BioallethrinCytochrome P450 2C8enzyme
BioallethrinCytochrome P450 2C9enzyme
BioallethrinCytochrome P450 2C19enzyme
BioallethrinCytochrome P450 3A4enzyme
BioallethrinCytochrome P450 2A1enzyme
BioallethrinCytochrome P450 1A1enzyme
BioallethrinCytochrome P450 2C6enzyme
BioallethrinCytochrome P450 2C11enzyme
BioallethrinCytochrome P450 3A1enzyme
BioallethrinCytochrome P450 3A2enzyme