Anthracenes

Name
Anthracenes
Accession Number
DBCAT001196
Description

Anthracenes with one ketone group.

Drugs
DrugDrug Description
MaprotilineA tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.
MitoxantroneA chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
DantronA drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx.
BanoxantroneFor the treatment of various forms of cancer.
OxaprotilineInvestigated for the treatment of depression.
AnthralinAn anthracene used to treat stable plaque psoriasis.
SennosidesA laxative used to treat constipation.
DiacereinAn slow-onset anthraquinone IL-1 inhibitor used in the treatment of degenerative joint diseases like osteoarthritis.
RheinNo approved indication.
EmodinEmodin has been investigated for the treatment of Polycystic Kidney.
AlloinNot Annotated
Frangula purshiana barkNot Annotated
QuinalizarinNot Available
OchromycinoneOchromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).
Drugs & Drug Targets
DrugTargetType
MaprotilineHistamine H1 receptortarget
MaprotilineSodium-dependent noradrenaline transportertarget
MaprotilineAlpha-1 adrenergic receptorstarget
MaprotilineCytochrome P450 2D6enzyme
MaprotilineAlpha-1-acid glycoprotein 1carrier
MaprotilineMuscarinic acetylcholine receptor M1target
MaprotilineMuscarinic acetylcholine receptor M2target
MaprotilineMuscarinic acetylcholine receptor M3target
MaprotilineMuscarinic acetylcholine receptor M4target
MaprotilineMuscarinic acetylcholine receptor M5target
MaprotilineCytochrome P450 1A2enzyme
Maprotiline5-hydroxytryptamine receptor 2Atarget
Maprotiline5-hydroxytryptamine receptor 2Ctarget
Maprotiline5-hydroxytryptamine receptor 7target
MaprotilineDopamine D2 receptortarget
MaprotilineAlpha-2 adrenergic receptorstarget
MitoxantroneDNA topoisomerase 2-alphatarget
MitoxantroneCytochrome P450 2E1enzyme
MitoxantroneP-glycoprotein 1transporter
MitoxantroneMultidrug resistance-associated protein 1transporter
MitoxantroneATP-binding cassette sub-family G member 2transporter
MitoxantroneDNAtarget
MitoxantroneCytochrome P450 1B1enzyme
MitoxantroneCytochrome P450 3A4enzyme
DantronSerum albumincarrier
BanoxantroneDNA topoisomerase 2-alphatarget
BanoxantroneCytochrome P450 3A4enzyme
BanoxantroneCytochrome P450 1A1enzyme
BanoxantroneCytochrome P450 2B6enzyme
AnthralinKeratin, type II cytoskeletal 2 epidermaltarget
AnthralinC-Jun-amino-terminal kinase-interacting protein 1target
AnthralinKeratin, type I cytoskeletal 12target
SennosidesReverse transcriptase/RNaseHtarget
SennosidesAquaporin-3target
DiacereinOxysterols receptor LXR-alphatarget
DiacereinOxysterols receptor LXR-betatarget
DiacereinArylamine N-acetyltransferasetarget
DiacereinArachidonate 5-lipoxygenasetarget
DiacereinCytochrome P450 1A2target
DiacereinCytochrome P450 3A Subfamilytarget
DiacereinCytochrome P450 2E1target
DiacereinCytochrome P450 2C9target
DiacereinCytochrome P450 2D6target
RheinOxysterols receptor LXR-alphatarget
RheinOxysterols receptor LXR-betatarget
RheinArylamine N-acetyltransferasetarget
RheinArachidonate 5-lipoxygenasetarget
RheinCytochrome P450 1A2enzyme
RheinCytochrome P450 3A Subfamilyenzyme
RheinCytochrome P450 2E1enzyme
RheinCytochrome P450 2C9enzyme
RheinCytochrome P450 2D6enzyme
EmodinCasein kinase II subunit alphatarget
EmodinPutative ketoacyl reductasetarget
Emodin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
EmodinAryl hydrocarbon receptortarget
QuinalizarinCasein kinase II subunit alphatarget