Name
Acrylates
Accession Number
DBCAT001443
Description

Derivatives of acrylic acid (the structural formula CH2=CHCO2H), including its salts and esters.

Drugs
DrugDrug Description
trans-urocanic acidNot Available
MyxothiazolNot Available
AP5280Investigated for use/treatment in solid tumors.
OsimertinibA tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
SpebrutinibSpebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
RociletinibRociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
OzagrelOzagrel has been used in trials studying the treatment of Dry Eye Syndromes.
2-octyl cyanoacrylateDermabond has been investigated for the basic science of Wound Healing.
VerdinexorKpt 335 is under investigation in clinical trial NCT02431364 (Trial of Safety and Tolerability of Oral Verdinexor (Verdinexor) in Healthy Adults).
EnbucrilateEnbucrilate is under investigation in clinical trial NCT02468206 (Secondary Prophylaxis of Gastric Variceal Bleed).
PAC-14028PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea.
DaporinadDaporinad has been used in trials studying the treatment of Melanoma, Cutaneous T-cell Lymphoma, and B-cell Chronic Lymphocytic Leukemia.
ACT-451840ACT-451840 has been used in trials studying Malaria.
PyrotinibPyrotinib is under investigation in clinical trial NCT03756064 (Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer).
OcrylateOcrylate is under investigation in clinical trial NCT01918059 (Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive).
AzoxystrobinAzoxystrobin is a methoxyacrylate analog and a strobilurin fungicide.
Drugs & Drug Targets
DrugTargetType
trans-urocanic acidUrocanate hydratasetarget
MyxothiazolCytochrome b-c1 complex subunit 1, mitochondrialtarget
OsimertinibEpidermal growth factor receptortarget
OsimertinibP-glycoprotein 1transporter
OsimertinibATP-binding cassette sub-family G member 2transporter
OsimertinibCytochrome P450 3A4enzyme
OsimertinibCytochrome P450 1A2enzyme
DaporinadNicotinamide phosphoribosyltransferasetarget
AzoxystrobinCytochrome c1, heme protein, mitochondrialtarget
AzoxystrobinCytochrome btarget
AzoxystrobinCytochrome b-c1 complex subunit 1, mitochondrialtarget
AzoxystrobinCytochrome b-c1 complex subunit 2, mitochondrialtarget
AzoxystrobinCytochrome b-c1 complex subunit 6, mitochondrialtarget
AzoxystrobinCytochrome b-c1 complex subunit 8target
AzoxystrobinCytochrome b-c1 complex subunit Rieske, mitochondrialtarget
AzoxystrobinCytochrome b-c1 complex subunit 10target
AzoxystrobinCytochrome b-c1 complex subunit 7target
AzoxystrobinCytochrome b-c1 complex subunit 9target