Histone Deacetylase Inhibitors
DBCAT001486Therapeutic category
Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains. A DrugBank category of 27 drugs. 7 of them are approved.
- Part of
- Antineoplastic Agents
- Also known as
- Antineoplastic histone deacetylase (HDAC) inhibitors · Deacetylase Inhibitor, Histone · Deacetylase Inhibitors, Histone · HDAC Inhibitors · Histone Deacetylase Inhibitor
- Drugs
- 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
- Abexinostat
- Acetyldinaline
- Alteminostat
- Belinostat
- Bufexamac
- Citarinostat
- CUDC-101
- Entinostat
- Fimepinostat
- Givinostat
- Ivaltinostat
- Mocetinostat
- Nanatinostat
- OBP-801
- Panobinostat
- Pracinostat
- R-306465
- Ricolinostat
- Romidepsin
- Scriptaid
- Tacedinaline
- Tefinostat
- Trichostatin A
- Tucidinostat
What you can answer from here — as of May 26, 2021
Which targets do Histone Deacetylase Inhibitors share, and which companies have late-stage candidates in this class?
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