Metals, Rare Earth

Metals, Rare Earth
Accession Number

A group of elements that include SCANDIUM; YTTRIUM; and the LANTHANOID SERIES ELEMENTS. Historically, the rare earth metals got their name from the fact that they were never found in their pure elemental form, but as an oxide. In addition they were very difficult to purify. They are not truly rare and comprise about 25% of the metals in the earth's crust.

DrugDrug Description
GadoteridolA gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize lesions and abnormal vascularity.
EP-2104RInvestigated for use/treatment in cardiovascular disorders and thrombosis.
Gadofosveset trisodiumAn intravenous contrast agent used during magnetic resonance angiography (MRA) to evaluate aortoiliac occlusive disease (AIOD) in adults with peripheral vascular disease.
Lanthanum carbonateA phosphate binder indicated for the reduction of serum phosphate in patients with end stage renal disease.
GadoliniumGadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease.
SamariumSamarium has been used in trials studying the treatment and prevention of Pain, Cancer, Metastasis, Prostate Cancer, and Metastatic Osteosarcoma, among others.
Samarium Sm-153A radiopharmaceutical indicated in the treatment of bone pain in patients with skeletal metastases.
Yttrium Y-90Yttrium 90 has been investigated for the treatment of Colon Cancer and Colorectal Cancer.
Lutetium Lu-177Not Annotated
NeodymiumNeodymium is under investigation in clinical trial NCT03525522 (Nd:Yttrium Aluminum Garnet Laser Treatment for Lichen Sclerosus).
AGuIXAGuIX is an investigational brand product consisting of a polysiloxane matrix and gadolinium chelates. It is under development as a radiosensitizer to be used during radiation treatment of malignant glioma.
Cerium dioxideNot Annotated
Drugs & Drug Targets
EP-2104RFibrinogen alpha chaintarget
Gadofosveset trisodiumSerum albumincarrier
Lanthanum carbonatePhosphatetarget