Accession Number

Cyclic compounds that include atoms other than carbon in their ring structure.

DrugDrug Description
TrabectedinAn alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
CasimiroinCasimiroin is a quinone reductase 2 inhibitor isolated from Casimiroa edulis.
BrecanavirFor the treatment of HIV-1 infection in combination with other antiretroviral agents.
TroxacitabineInvestigated for use/treatment in leukemia (myeloid).
ORG-34517Investigated for use/treatment in depression.
AtrasentanInvestigated for use/treatment in prostate cancer and cancer/tumors (unspecified).
AmdoxovirInvestigated for use/treatment in HIV infection and acquired immune deficiency syndrome (AIDS) and aids-related infections.
ProtokylolProtokylol is a ╬▓-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
StiripentolAn antiepileptic agent used in combination with other anticonvulsants to treat seizures associated with Dravet syndrome.
LumacaftorA protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene.
Piperonyl butoxideA pesticide used as a potentiator ingredient in the treatment of pediculosis (head lice, body lice or crabs) to boost efficacy of treatment.
TezacaftorA medication used to treat homozygous or heterozygous F508del mutation cystic fibrosis.
SaracatinibSaracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer.
PrulifloxacinA broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections.
PiperineBioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
ZelavespibZelavespib (PU-H71) has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic Solid Tumor, and Myeloproliferative Neoplasms (MPN).
DomiodolNot Annotated
EmrusolminEmrusolmin restores hippocampal synaptic and transcriptional plasticity as well as spatial memory in a mouse model for Alzheimer's disease, when given orally before or after the onset of pathology.
Ciclonium bromideNot Annotated
CepharanthineNot Annotated
IndotecanNot Annotated
Drugs & Drug Targets
TrabectedinCytochrome P450 3A4enzyme
TrabectedinCytochrome P450 2C9enzyme
TrabectedinCytochrome P450 2D6enzyme
TrabectedinCytochrome P450 2E1enzyme
TrabectedinCytochrome P450 2C19enzyme
TrabectedinProstaglandin G/H synthase 1enzyme
CasimiroinRibosyldihydronicotinamide dehydrogenase [quinone]target
BrecanavirHuman immunodeficiency virus type 1 proteasetarget
TroxacitabineDeoxycytidine kinaseenzyme
ORG-34517Glucocorticoid receptortarget
AtrasentanEndothelin-1 receptortarget
AmdoxovirReverse transcriptase/RNaseHtarget
ProtokylolBeta-2 adrenergic receptortarget
StiripentolCytochrome P450 2C19enzyme
StiripentolCytochrome P450 2D6enzyme
StiripentolCytochrome P450 3A4enzyme
StiripentolCytochrome P450 1A2enzyme
StiripentolCytochrome P450 2C9enzyme
StiripentolGABA(A) Receptortarget
StiripentolL-lactate dehydrogenase A chaintarget
StiripentolL-lactate dehydrogenase B chaintarget
StiripentolCytochrome P450 2B6enzyme
StiripentolCytochrome P450 2C8enzyme
StiripentolP-glycoprotein 1transporter
StiripentolATP-binding cassette sub-family G member 2transporter
LumacaftorCytochrome P450 2B6enzyme
LumacaftorCytochrome P450 2C8enzyme
LumacaftorCytochrome P450 2C9enzyme
LumacaftorCytochrome P450 2C19enzyme
LumacaftorSerum albumincarrier
LumacaftorCystic fibrosis transmembrane conductance regulatortarget
LumacaftorCytochrome P450 3A4enzyme
LumacaftorP-glycoprotein 1transporter
TezacaftorCytochrome P450 3A4enzyme
TezacaftorCytochrome P450 3A5enzyme
TezacaftorCystic fibrosis transmembrane conductance regulatortarget
TezacaftorP-glycoprotein 1transporter
TezacaftorATP-binding cassette sub-family G member 2transporter
TezacaftorSolute carrier family 22 member 2transporter
TezacaftorSolute carrier family 22 member 6transporter
TezacaftorSolute carrier family 22 member 8transporter
TezacaftorSolute carrier organic anion transporter family member 1B1transporter
TezacaftorCytochrome P450 1A2enzyme
TezacaftorCytochrome P450 2B6enzyme
TezacaftorCytochrome P450 2C8enzyme
TezacaftorCytochrome P450 2C9enzyme
TezacaftorCytochrome P450 2C19enzyme
TezacaftorCytochrome P450 2D6enzyme
TezacaftorSolute carrier organic anion transporter family member 1B3transporter
SaracatinibCytochrome P450 3A4enzyme
PrulifloxacinCytochrome P450 1A2enzyme
PiperineNuclear receptor subfamily 1 group I member 2target
PiperineCytochrome P450 3A4enzyme
PiperineP-glycoprotein 1transporter