Anterior Pituitary Lobe Hormones and Analogues

Name
Anterior Pituitary Lobe Hormones and Analogues
Accession Number
DBCAT002096
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
SermorelinFor the treatment of dwarfism, prevention of HIV-induced weight loss
SomatotropinA recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.
PegvisomantA growth hormone receptor antagonist used to treat acromegaly.
MecaserminA recombinant insulin-like growth factor-1 used for the long-term treatment of growth failure in pediatric patients with primary IGF-1 deficiency or with growth hormone gene deletion due to the development of neutralizing antibodies to GH.
TetracosactideA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
TesamorelinA growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy.
SomatremA recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age.
Thyrotropin alfaA recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue.
Mecasermin rinfabateMecasermin rinfabate was approved for treatment of severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) ....
Drugs & Drug Targets
DrugTargetType
SermorelinGrowth hormone-releasing hormone receptortarget
SomatotropinGrowth hormone receptortarget
SomatotropinProlactin receptortarget
SomatotropinCytochrome P450 1A2enzyme
SomatotropinCytochrome P450 2C19enzyme
SomatotropinP-glycoprotein 1transporter
PegvisomantGrowth hormone receptortarget
PegvisomantSterol 26-hydroxylase, mitochondrialenzyme
PegvisomantGlutamine synthetaseenzyme
PegvisomantCytochrome P450 3A4enzyme
PegvisomantCholinesteraseenzyme
PegvisomantCytochrome P450 4A11enzyme
MecaserminInsulin-like growth factor 1 receptortarget
MecaserminInsulin-like growth factor-binding protein 3target
MecaserminInsulin receptortarget
MecaserminCation-independent mannose-6-phosphate receptortarget
MecaserminInsulin-like growth factor-binding protein 3carrier
MecaserminInsulin-like growth factor-binding protein complex acid labile subunitcarrier
MecaserminInsulin-like growth factor-binding protein 1carrier
MecaserminInsulin-like growth factor-binding protein 2carrier
MecaserminInsulin-like growth factor-binding protein 4carrier
MecaserminInsulin-like growth factor-binding protein 5carrier
MecaserminInsulin-like growth factor-binding protein 6carrier
TetracosactideAdrenocorticotropic hormone receptortarget
CorticotropinAdrenocorticotropic hormone receptortarget
CorticotropinCorticoliberintarget
Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CorticotropinCytochrome P450 3A4enzyme
TesamorelinGrowth hormone-releasing hormone receptortarget
SomatremGrowth hormone receptortarget
SomatremInsulin-like growth factor 1 receptortarget
Thyrotropin alfaThyrotropin receptortarget
Mecasermin rinfabateInsulin-like growth factor 1 receptortarget
Mecasermin rinfabateInsulin receptortarget
Mecasermin rinfabateCation-independent mannose-6-phosphate receptortarget