Calcium Homeostasis

Name
Calcium Homeostasis
Accession Number
DBCAT002102
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
Salmon calcitoninA synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
ParicalcitolA vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease.
CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
Parathyroid hormoneAn analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism.
TeriparatideA recombinant parathyroid hormone used for the treatment of osteoporosis.
DoxercalciferolA synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis.
Human calcitoninHuman calcitonin is indicated for the treatment of Paget's disease in the cases where the use of salmon calcitonin may provoke the generation of high-titer of antibodies. Paget's disease is...
Calcitonin porcineCalcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. Human calcitonin...
ElcatoninNot Annotated
EtelcalcetideA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in patients with chronic kidney disease who require hemodialysis.
CalcifediolAn active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients.
AbaloparatideA parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in patients with a high risk of fracture.
Drugs & Drug Targets
DrugTargetType
Salmon calcitoninCalcitonin receptortarget
ParicalcitolVitamin D3 receptortarget
Paricalcitol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
ParicalcitolCytochrome P450 3A4enzyme
ParicalcitolUDP-glucuronosyltransferase 1-4enzyme
CinacalcetExtracellular calcium-sensing receptortarget
CinacalcetCytochrome P450 3A4enzyme
CinacalcetCytochrome P450 2D6enzyme
CinacalcetCytochrome P450 1A2enzyme
Parathyroid hormoneParathyroid hormone/parathyroid hormone-related peptide receptortarget
Parathyroid hormoneParathyroid hormone 2 receptortarget
TeriparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DoxercalciferolSterol 26-hydroxylase, mitochondrialenzyme
DoxercalciferolVitamin D3 receptortarget
Human calcitoninAlpha-actinin-1target
Human calcitoninAlpha-N-acetylglucosaminidaseenzyme
Human calcitoninAminopeptidase Nenzyme
Human calcitoninPhosphoglucomutase-1enzyme
EtelcalcetideExtracellular calcium-sensing receptortarget
Calcifediol25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
CalcifediolVitamin D3 receptortarget
Calcifediol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
AbaloparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget