| Enfuvirtide | An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals. |
| Oseltamivir | A neuraminidase inhibitor used in the prophylaxis and treatment of influenza. |
| Nelfinavir | A viral protease inhibitor used in the treatment of HIV infection. |
| Indinavir | A protease inhibitor used to treat HIV infection. |
| Nevirapine | A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. |
| Penciclovir | A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. |
| Tenofovir disoproxil | A nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection. |
| Cidofovir | An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS. |
| Famciclovir | A nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster. |
| Entecavir | A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases. |
| Zidovudine | A dideoxynucleoside used in the treatment of HIV infection. |
| Ritonavir | An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. |
| Foscarnet | An antiviral used to treat CMV, HIV, and HSV infections. |
| Zanamivir | A neuraminidase inhibitor used to treat influenza A and B. |
| Valaciclovir | An guanine nucleoside antiviral used to treat herpes exacerbations. |
| Efavirenz | A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. |
| Stavudine | A dideoxynucleoside used in the treatment of HIV infection. |
| Amprenavir | A protease inhibitor used to treat HIV infection. |
| Delavirdine | A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. |
| Lamivudine | A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. |
| Adefovir dipivoxil | A nucleotide analog used to treat chronic hepatitis B. |
| Ribavirin | A guanosine nucleoside used to treat some forms of Hepatitis C. |
| Emtricitabine | A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. |
| Didanosine | A reverse transcriptase inhibitor used to treat HIV. |
| Tipranavir | A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. |
| Zalcitabine | A dideoxynucleoside used to treat HIV. |
| Abacavir | An antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. |
| Atazanavir | An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. |
| Saquinavir | An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. |
| Telbivudine | A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST). |
| Fosamprenavir | An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. |
| Lopinavir | An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. |
| Valganciclovir | An antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS). |
| Maraviroc | A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. |
| Pleconaril | Investigated for use/treatment in upper respiratory infection. |
| Telaprevir | An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. |
| Maribavir | Investigated for use/treatment in viral infection, transplantation (organ or tissue), cytomegalovirus (CMV) retinitis, and retinal disorders (unspecified). |
| Etravirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. |
| Clevudine | Investigated for use/treatment in hepatitis (viral, B). |
| Raltegravir | An antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals. |
| Rilpivirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). |
| Boceprevir | A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. |
| Dolutegravir | An antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents. |
| Sofosbuvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
| Ledipasvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
| Elvitegravir | An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. |
| Daclatasvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
| Dasabuvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
| Ombitasvir | A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. |
| Paritaprevir | A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. |
| Tenofovir alafenamide | A nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease. |
| Asunaprevir | An NS3 protease inhibitor used to treat hepatitis C genotype 1b. |
| Faldaprevir | Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. |
| Moroxydine | Not Annotated |
| Umifenovir | A dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses. |
| Metisazone | Not Annotated |
| Vidarabine | An antiviral agent used to treat various viral infections. |
| Idoxuridine | A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. |
| Acyclovir | A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. |
| Ganciclovir | A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. |
| Darunavir | A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. |
| Simeprevir | A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. |
| Tromantadine | Tromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex. |
| Baloxavir marboxil | A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza. |
| Brivudine | Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries. |
| Peramivir | An intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days. |
| Elbasvir | An antiviral and NS5A inhibitor used to treat hepatitis C infections. |
| Grazoprevir | An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. |
| Velpatasvir | A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis. |
| Bictegravir | An integrase inhibitor used to treat HIV infections. |
| Voxilaprevir | A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. |
| Letermovir | An antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). |
| Doravirine | A non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections. |
| Ibalizumab | A CD4-specific antibody used to treat HIV infections. |
| Pibrentasvir | A Hepatitis C NS5A inhibitor used to treat Hepatitis C. |
| Glecaprevir | A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. |
| TMC-310911 | TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections.... |
| GS-441524 | An experimental nucleoside analog antiviral investigated for its use in the treatment of Ebola and SARS-CoV-2 infections. |
| Amenamevir | Amenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir. |
| Tecovirimat | An antiviral medication used to treat smallpox. |
| Beclabuvir | Beclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic. |
| Favipiravir | An antiviral used to manage influenza, and that has the potential to target other viral infections. |
| Laninamivir | Laninamivir has been used in trials studying the treatment of Influenza. |