Serotonin 5-HT3 Receptor Antagonists
- Name
- Serotonin 5-HT3 Receptor Antagonists
- Accession Number
- DBCAT002341 (DBCAT001738, DBCAT003341, DBCAT003736)
- Description
Drugs that bind to but do not activate SEROTONIN 5-HT3 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT3 RECEPTOR AGONISTS.
- ATC Classification
- Drugs
Drug Drug Description Alosetron A 5-HT3 antagonist used to treat diarrhea-predominant IBS. Dolasetron An antinauseant and antiemetic used in chemotherapy and postoperatively. Esmirtazapine Investigated for use/treatment in insomnia and sleep disorders. Granisetron A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. Mirtazapine A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite. Ondansetron A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively. Palonosetron A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. Tropisetron A 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting. Vortioxetine A serotonin modulating antidepressant indicated for the treatment of major depressive disorder (MDD).