Cytochrome P-450 CYP3A4 Inducers (strong)
- Cytochrome P-450 CYP3A4 Inducers (strong)
- Accession Number
Drug Drug Description Rifampicin An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. Carbamazepine An anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia. Fosphenytoin An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. Pentobarbital A barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. Phenobarbital A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. Phenytoin An anticonvulsant drug used in the prophylaxis and control of various types of seizures. Primidone An antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures. Enzalutamide An androgen receptor inhibitor used to treat castration-resistant prostate cancer. Lumacaftor A protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene. St. John's Wort An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety. Mitotane An adrenal cortex inhibitor used to treat adrenocortical tumors and Cushing's syndrome. Apalutamide An androgen receptor inhibitor used to treat non metastatic, castration resistant prostate cancer. Rimexolone A glucocorticoid used to treat inflammation of the eye. Rifaximin A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. Rifamycin An antibacterial used to treat traveler's diarrhea. Midostaurin An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). Dexamethasone A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. Rifapentine An antibiotic agent used in the treatment of pulmonary tuberculosis.
- Drugs & Drug Targets