Antihelminthic

Name
Antihelminthic
Accession Number
DBCAT003367
Description

Not Available

Drugs
DrugDrug Description
AlbendazoleA benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections.
DiethylcarbamazineAn anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa.
MebendazoleA benzimidazole anthelmintic used to treat helminth infections.
OxamniquineFor treatment of Schistosomiasis caused by Schistosoma mansoni
PraziquantelAn anthelmintic medication used to treat parasitic worm infections such as schistosomiasis, clonorchiasis, and opisthorchiasis
ThiabendazoleA benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.
TriclabendazoleAn anthelmintic drug used to treat fascioliasis.
Drugs & Drug Targets
DrugTargetType
AlbendazoleTubulin alpha-1A chaintarget
AlbendazoleTubulin beta-4B chaintarget
AlbendazoleCytochrome P450 3A4enzyme
AlbendazoleFumarate reductase (cytochrome)target
AlbendazoleCytochrome P450 1A1enzyme
AlbendazoleCytochrome P450 1A2enzyme
AlbendazoleTubulin beta chaintarget
AlbendazoleCytochrome P450 2C19enzyme
AlbendazoleATP-dependent translocase ABCB1transporter
DiethylcarbamazinePolyunsaturated fatty acid 5-lipoxygenasetarget
DiethylcarbamazineProstaglandin G/H synthase 1target
DiethylcarbamazineCholinesteraseenzyme
MebendazoleTubulin alpha-1A chaintarget
MebendazoleTubulin beta-4B chaintarget
MebendazoleCytochrome P450 1A1enzyme
MebendazoleCytochrome P450 3A Subfamilyenzyme
OxamniquineCytochrome P450 2D6enzyme
OxamniquineDNAtarget
PraziquantelCytochrome P450 3A4enzyme
PraziquantelSchistosome calcium ion (Ca2+) channelstarget
PraziquantelCytochrome P450 1A2enzyme
PraziquantelCytochrome P450 2C19enzyme
PraziquantelCytochrome P450 3A5enzyme
PraziquantelAlbumincarrier
PraziquantelHematopoietic prostaglandin D synthasetarget
ThiabendazoleCytochrome P450 1A1enzyme
ThiabendazoleCytochrome P450 1A2enzyme
ThiabendazoleFumarate reductase flavoprotein subunittarget
TriclabendazoleCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 2C9enzyme
TriclabendazoleExcretory Secretory (ES) proteinstarget
TriclabendazoleCytochrome P450 3A4enzyme
TriclabendazoleCytochrome P450 1A1enzyme
TriclabendazoleCytochrome P450 1B1enzyme
TriclabendazoleCytochrome P450 2C19enzyme
TriclabendazoleCytochrome P450 2D6enzyme
TriclabendazoleCytochrome P450 2A6enzyme
TriclabendazoleCytochrome P450 2C8enzyme
TriclabendazoleCytochrome P450 2B6enzyme
TriclabendazoleCruzipaintarget