Cytochrome P-450 CYP3A5 Inhibitors (strength unknown)

Name
Cytochrome P-450 CYP3A5 Inhibitors (strength unknown)
Accession Number
DBCAT004487
Description
Not Available
Drugs
DrugDrug Description
SaquinavirAn HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
TelithromycinAn ketolide used to treat community acquired pneumonia of mild to moderate severity.
AprepitantA substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
ChloramphenicolA broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
DelavirdineA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
GestodeneGestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol...
MibefradilFor the treatment of angina and high blood pressure.
SeproxetineSeproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an...
VoriconazoleA triazole compound used to treat fungal infections.
PhenelzineA monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
IdelalisibAn antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
OxymetholoneAn anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias.
ElbasvirAn antiviral and NS5A inhibitor used to treat hepatitis C infections.
RucaparibAn anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.
LetermovirAn antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT).
SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
TemsirolimusA antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
FluticasoneFluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is...
Fluticasone furoateAn inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis.
DitiocarbA chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
CannabidiolAn active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
Medical CannabisThe use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical...
NabiximolsIn Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have...
Curcumin sulfateNo approved therapeutic indications.
OxcarbazepineAn anti-epileptic used in the treatment of partial-onset seizures.
DronedaroneAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
CenobamateA small molecule drug indicated to treat partial onset seizures in adults.
Methylene blueAn oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
ClofazimineA riminophenazine antimycobacterial used to treat leprosy.
PralsetinibA RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.
Drugs & Drug Targets
DrugTargetType
SaquinavirHuman immunodeficiency virus type 1 proteasetarget
SaquinavirCytochrome P450 3A4enzyme
SaquinavirCytochrome P450 3A5enzyme
SaquinavirAlpha-1-acid glycoprotein 1carrier
SaquinavirSerum albumincarrier
SaquinavirCytochrome P450 3A7enzyme
SaquinavirP-glycoprotein 1transporter
SaquinavirSolute carrier family 22 member 1transporter
SaquinavirSolute carrier organic anion transporter family member 1A2transporter
SaquinavirATP-binding cassette sub-family G member 2transporter
SaquinavirSolute carrier organic anion transporter family member 1B1transporter
SaquinavirMultidrug resistance-associated protein 1transporter
SaquinavirCanalicular multispecific organic anion transporter 1transporter
SaquinavirCytochrome P450 2C8enzyme
SaquinavirCytochrome P450 2D6enzyme
SaquinavirSolute carrier organic anion transporter family member 2B1transporter
SaquinavirBile salt export pumptransporter
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
Telithromycin23S ribosomal RNAtarget
TelithromycinCytochrome P450 3A4enzyme
TelithromycinSolute carrier organic anion transporter family member 1B1transporter
TelithromycinSolute carrier organic anion transporter family member 1B3transporter
AprepitantNeurokinin 1 receptortarget
AprepitantCytochrome P450 3A4enzyme
AprepitantCytochrome P450 2C9enzyme
AprepitantCytochrome P450 2C19enzyme
ChloramphenicolComplement decay-accelerating factortarget
ChloramphenicolDr hemagglutinin structural subunittarget
ChloramphenicolCytochrome P450 2C19enzyme
ChloramphenicolCytochrome P450 3A4enzyme
ChloramphenicolCytochrome P450 3A5enzyme
ChloramphenicolCytochrome P450 3A7enzyme
ChloramphenicolSolute carrier family 22 member 6transporter
Chloramphenicol50S ribosomal protein L16target
ChloramphenicolChloramphenicol acetyltransferase 3enzyme
ChloramphenicolChloramphenicol acetyltransferaseenzyme
ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
DelavirdineCytochrome P450 3A4enzyme
DelavirdineCytochrome P450 2C9enzyme
DelavirdineCytochrome P450 2D6enzyme
DelavirdineCytochrome P450 3A5enzyme
DelavirdineCytochrome P450 3A7enzyme
DelavirdineCytochrome P450 2C19enzyme
DelavirdineReverse transcriptase/RNaseHtarget
GestodeneCytochrome P450 3A5enzyme
GestodeneCytochrome P450 3A7enzyme
GestodeneProgesterone receptortarget
GestodeneCytochrome P450 3A4enzyme
GestodeneCytochrome P450 2C19enzyme
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
MibefradilCytochrome P450 3A4enzyme
MibefradilCytochrome P450 1A2enzyme
MibefradilCytochrome P450 2D6enzyme
MibefradilCytochrome P450 3A5enzyme
MibefradilCytochrome P450 3A7enzyme
MibefradilP-glycoprotein 1transporter
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
MibefradilCytochrome P450 11B1, mitochondrialenzyme
MibefradilCytochrome P450 11B2, mitochondrialenzyme
SeproxetineCytochrome P450 3A5enzyme
SeproxetineCytochrome P450 3A7enzyme
SeproxetineCytochrome P450 2C9enzyme
SeproxetineCytochrome P450 2C19enzyme
SeproxetineCytochrome P450 3A4enzyme
VoriconazoleCytochrome P450 2C19enzyme
VoriconazoleCytochrome P450 3A4enzyme
VoriconazoleCytochrome P450 2C9enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
VoriconazoleCytochrome P450 3A5enzyme
VoriconazoleCytochrome P450 3A7enzyme
VoriconazoleProstaglandin G/H synthase 1enzyme
VoriconazoleCytochrome P450 51target
VoriconazoleCytochrome P450 2B6enzyme
PhenelzineMembrane primary amine oxidasetarget
PhenelzineAmine oxidase [flavin-containing] Btarget
PhenelzineAmine oxidase [flavin-containing] Atarget
PhenelzineAmine oxidase [flavin-containing] Aenzyme
PhenelzineAmine oxidase [flavin-containing] Benzyme
PhenelzineCytochrome P450 2E1enzyme
Phenelzine4-aminobutyrate aminotransferase, mitochondrialtarget
PhenelzineGlutamic acid decarboxylasetarget
PhenelzineAlanine aminotransferase 1target
PhenelzineAlanine aminotransferase 2target
PhenelzineCytochrome P450 2C19enzyme
PhenelzineCytochrome P450 2C8enzyme
PhenelzineCytochrome P450 3A4enzyme
PhenelzineCytochrome P450 3A5enzyme
PhenelzineCytochrome P450 3A7enzyme
PhenelzineCytochrome P450 2D6enzyme
PhenelzineCytochrome P450 3A Subfamilyenzyme
Fluticasone propionateCorticosteroid-binding globulincarrier
Fluticasone propionateCytosolic phospholipase A2target
Fluticasone propionateGlucocorticoid receptortarget
Fluticasone propionateCytochrome P450 3A4enzyme
Fluticasone propionateProgesterone receptortarget
Fluticasone propionateMineralocorticoid receptortarget
Fluticasone propionateCytochrome P450 3A5enzyme
Fluticasone propionateCytochrome P450 3A7enzyme
Fluticasone propionateCytochrome P450 2C8enzyme
Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
Fluticasone propionateP-glycoprotein 1transporter
Fluticasone propionateSolute carrier organic anion transporter family member 1B1transporter
CrizotinibCytochrome P450 3A4enzyme
CrizotinibCytochrome P450 3A5enzyme
CrizotinibP-glycoprotein 1transporter
CrizotinibALK tyrosine kinase receptortarget
CrizotinibHepatocyte growth factor receptortarget
CrizotinibCytochrome P450 2B6enzyme
CrizotinibCytochrome P450 3A Subfamilyenzyme
IdelalisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
IdelalisibATP-binding cassette sub-family G member 2transporter
IdelalisibP-glycoprotein 1transporter
IdelalisibAldehyde oxidaseenzyme
IdelalisibCytochrome P450 2C8enzyme
IdelalisibCytochrome P450 2C19enzyme
IdelalisibCytochrome P450 2B6enzyme
IdelalisibCytochrome P450 3A4enzyme
IdelalisibSolute carrier organic anion transporter family member 1B1transporter
IdelalisibSolute carrier organic anion transporter family member 1B3transporter
IdelalisibCytochrome P450 3A5enzyme
IdelalisibCytochrome P450 3A43enzyme
IdelalisibCytochrome P450 3A7enzyme
IdelalisibUDP-glucuronosyltransferase 1-4enzyme
OxymetholoneAndrogen receptortarget
OxymetholoneSerum albumincarrier
OxymetholoneSex hormone-binding globulincarrier
OxymetholoneNatriuretic peptides Btarget
OxymetholoneAmine oxidase [flavin-containing] Aenzyme
OxymetholoneCytochrome P450 2D6enzyme
Oxymetholone3-oxo-5-alpha-steroid 4-dehydrogenase 1enzyme
OxymetholoneCytochrome P450 3A4enzyme
OxymetholoneCytochrome P450 3A5enzyme
OxymetholoneCytochrome P450 3A7enzyme
OxymetholoneCytochrome P450 3A43enzyme
ElbasvirNonstructural protein 5Atarget
ElbasvirP-glycoprotein 1transporter
ElbasvirCytochrome P450 3A4enzyme
ElbasvirCytochrome P450 3A5enzyme
ElbasvirCytochrome P450 3A7enzyme
ElbasvirCytochrome P450 3A43enzyme
RucaparibPoly [ADP-ribose] polymerase 1target
RucaparibPoly [ADP-ribose] polymerase 2target
RucaparibPoly [ADP-ribose] polymerase 3target
RucaparibCytochrome P450 2D6enzyme
RucaparibCytochrome P450 1A2enzyme
RucaparibCytochrome P450 3A4enzyme
RucaparibP-glycoprotein 1transporter
RucaparibATP-binding cassette sub-family G member 2transporter
RucaparibMultidrug and toxin extrusion protein 1transporter
RucaparibMultidrug and toxin extrusion protein 2transporter
RucaparibSolute carrier family 22 member 1transporter
RucaparibMultidrug resistance-associated protein 4transporter
RucaparibSolute carrier organic anion transporter family member 1B1transporter
RucaparibSolute carrier organic anion transporter family member 1B3transporter
RucaparibSolute carrier family 22 member 6transporter
RucaparibSolute carrier family 22 member 8transporter
RucaparibCytochrome P450 3A5enzyme
RucaparibCytochrome P450 3A7enzyme
RucaparibCytochrome P450 3A43enzyme
RucaparibCytochrome P450 2C19enzyme
RucaparibCytochrome P450 2C9enzyme
RucaparibCytochrome P450 2C8enzyme
RucaparibUDP-glucuronosyltransferase 1-1enzyme
LetermovirUDP-glucuronosyltransferase 1-1enzyme
LetermovirUDP-glucuronosyltransferase 1-3enzyme
LetermovirSolute carrier organic anion transporter family member 1B1transporter
LetermovirSolute carrier organic anion transporter family member 1B3transporter
LetermovirTripartite terminase subunit 1target
LetermovirTripartite terminase subunit 2target
LetermovirTripartite terminase subunit 3target
LetermovirCytochrome P450 2D6enzyme
LetermovirCytochrome P450 2C8enzyme
LetermovirCytochrome P450 2C19enzyme
LetermovirCytochrome P450 2C9enzyme
LetermovirCytochrome P450 2B6enzyme
LetermovirP-glycoprotein 1transporter
LetermovirATP-binding cassette sub-family G member 2transporter
LetermovirBile salt export pumptransporter
LetermovirSolute carrier family 22 member 8transporter
LetermovirCanalicular multispecific organic anion transporter 1transporter
LetermovirCytochrome P450 3A4enzyme
LetermovirCytochrome P450 3A5enzyme
LetermovirCytochrome P450 3A7enzyme
LetermovirCytochrome P450 3A43enzyme
SafinamideAmine oxidase [flavin-containing] Btarget
SafinamideAmine oxidase [flavin-containing] Aenzyme
SafinamideATP-binding cassette sub-family G member 2transporter
SafinamideSolute carrier organic anion transporter family member 3A1transporter
SafinamideCytochrome P450 3A4enzyme
SafinamideCytochrome P450 1A1enzyme
SafinamideCytochrome P450 1A2enzyme
SafinamideCytochrome P450 2B6enzyme
SafinamideCytochrome P450 2C9enzyme
SafinamideCytochrome P450 2D6enzyme
SafinamideCytochrome P450 2C19enzyme
SafinamideCytochrome P450 2E1enzyme
SafinamideCytochrome P450 3A5enzyme
TroglitazonePeroxisome proliferator-activated receptor gammatarget
TroglitazoneLong-chain-fatty-acid--CoA ligase 4target
TroglitazonePlasminogen activator inhibitor 1target
TroglitazoneEquilibrative nucleoside transporter 1target
TroglitazoneCytochrome P450 3A4enzyme
TroglitazoneCytochrome P450 2C19enzyme
TroglitazoneUDP-glucuronosyltransferase 1-1enzyme
TroglitazoneCytochrome P450 2C8enzyme
TroglitazoneBile salt export pumptransporter
TroglitazoneSolute carrier organic anion transporter family member 1B1transporter
TroglitazoneEstrogen-related receptor gammatarget
TroglitazoneSteroid hormone receptor ERR1target
TroglitazoneCytochrome P450 19A1enzyme
TroglitazoneCytochrome P450 1A1enzyme
TroglitazoneCytochrome P450 2B6enzyme
TroglitazoneCytochrome P450 2C9enzyme
TroglitazoneCytochrome P450 3A5enzyme
TroglitazoneCytochrome P450 3A7enzyme
TroglitazoneUDP-glucuronosyltransferase 1-3enzyme
TroglitazoneUDP-glucuronosyltransferase 1-4enzyme
TroglitazoneUDP-glucuronosyltransferase 1-6enzyme
TroglitazoneUDP-glucuronosyltransferase 1-7enzyme
TroglitazoneUDP-glucuronosyltransferase 1-8enzyme
TroglitazoneUDP-glucuronosyltransferase 1-9enzyme
TroglitazoneUDP-glucuronosyltransferase 1-10enzyme
TroglitazoneUDP-glucuronosyltransferase 2B7enzyme
TroglitazoneUDP-glucuronosyltransferase 2B15enzyme
TroglitazonePeroxisome proliferator-activated receptor deltatarget
TroglitazonePeroxisome proliferator-activated receptor alphatarget
TroglitazoneGlutathione S-transferase Ptarget
TemsirolimusSerine/threonine-protein kinase mTORtarget
TemsirolimusCytochrome P450 3A4enzyme
TemsirolimusCytochrome P450 3A5enzyme
TemsirolimusCytochrome P450 3A7enzyme
TemsirolimusCytochrome P450 2D6enzyme
TemsirolimusP-glycoprotein 1transporter
Erythromycin23S ribosomal RNAtarget
ErythromycinCytochrome P450 3A4enzyme
ErythromycinCytochrome P450 3A7enzyme
ErythromycinP-glycoprotein 1transporter
ErythromycinSolute carrier organic anion transporter family member 1B1transporter
ErythromycinMotilin receptortarget
ErythromycinPotassium voltage-gated channel subfamily H member 2target
ErythromycinCytochrome P450 3A5enzyme
ErythromycinSolute carrier organic anion transporter family member 1B3transporter
ErythromycinBile salt export pumptransporter
ErythromycinCanalicular multispecific organic anion transporter 1transporter
ErythromycinSolute carrier organic anion transporter family member 1A2transporter
FluticasoneCytochrome P450 3A4enzyme
FluticasoneCytochrome P450 2C8enzyme
FluticasoneP-glycoprotein 1carrier
FluticasoneSolute carrier organic anion transporter family member 1B1carrier
FluticasoneP-glycoprotein 1transporter
FluticasoneSolute carrier organic anion transporter family member 1B1transporter
FluticasoneGlucocorticoid receptortarget
FluticasoneCorticosteroid-binding globulincarrier
FluticasoneCytochrome P450 3A5enzyme
FluticasoneCytochrome P450 3A7enzyme
FluticasoneProgesterone receptortarget
FluticasoneCytosolic phospholipase A2target
FluticasoneMineralocorticoid receptortarget
Fluticasone furoateCytochrome P450 3A4enzyme
Fluticasone furoateGlucocorticoid receptortarget
Fluticasone furoateP-glycoprotein 1transporter
Fluticasone furoateCytochrome P450 2C8enzyme
Fluticasone furoateSolute carrier organic anion transporter family member 1B1transporter
Fluticasone furoateCorticosteroid-binding globulincarrier
Fluticasone furoateP-glycoprotein 1carrier
Fluticasone furoateSolute carrier organic anion transporter family member 1B1carrier
Fluticasone furoateCytochrome P450 3A5enzyme
Fluticasone furoateCytochrome P450 3A7enzyme
Fluticasone furoateProgesterone receptortarget
Fluticasone furoateMineralocorticoid receptortarget
DitiocarbCytochrome P450 2E1enzyme
DitiocarbCytochrome P450 3A4enzyme
DitiocarbCytochrome P450 3A5enzyme
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NicardipineCytochrome P450 3A4enzyme
NicardipineCytochrome P450 2C19enzyme
NicardipineCytochrome P450 2C8enzyme
NicardipineCytochrome P450 2D6enzyme
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
NicardipineAlpha-1A adrenergic receptortarget
NicardipineAlpha-1D adrenergic receptortarget
NicardipineAlpha-1B adrenergic receptortarget
NicardipineMuscarinic acetylcholine receptor M1target
NicardipineMuscarinic acetylcholine receptor M2target
NicardipineMuscarinic acetylcholine receptor M3target
NicardipineMuscarinic acetylcholine receptor M4target
NicardipineMuscarinic acetylcholine receptor M5target
NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NicardipineCalmodulintarget
NicardipineP-glycoprotein 1transporter
NicardipineCytochrome P450 2B6enzyme
NicardipineCytochrome P450 2E1enzyme
NicardipineCytochrome P450 3A5enzyme
NicardipineSolute carrier organic anion transporter family member 1B1transporter
NicardipineBile salt export pumptransporter
NicardipineCytochrome P450 2C9enzyme
CannabidiolCytochrome P450 2C9enzyme
CannabidiolCytochrome P450 2C19enzyme
CannabidiolCytochrome P450 2D6enzyme
CannabidiolCytochrome P450 3A4enzyme
CannabidiolCannabinoid receptor 1target
CannabidiolCannabinoid receptor 2target
CannabidiolG-protein coupled receptor 12target
CannabidiolGlycine receptor subunit alpha-1target
CannabidiolGlycine receptor (alpha-1/beta)target
CannabidiolGlycine receptor subunit alpha-3target
CannabidiolN-arachidonyl glycine receptortarget
CannabidiolG-protein coupled receptor 55target
Cannabidiol5-hydroxytryptamine receptor 1Atarget
Cannabidiol5-hydroxytryptamine receptor 2Atarget
CannabidiolNeuronal acetylcholine receptor subunit alpha-7target
CannabidiolDelta-type opioid receptortarget
CannabidiolMu-type opioid receptortarget
CannabidiolPeroxisome proliferator-activated receptor gammatarget
CannabidiolCytochrome P450 3A5enzyme
CannabidiolArylalkylamine N-acetyltransferaseenzyme
CannabidiolCytochrome P450 1A1enzyme
CannabidiolFatty-acid amide hydrolase 1enzyme
CannabidiolArachidonate 5-lipoxygenaseenzyme
CannabidiolArachidonate 15-lipoxygenaseenzyme
CannabidiolQuinone oxidoreductaseenzyme
CannabidiolMultidrug resistance-associated protein 1transporter
CannabidiolATP-binding cassette sub-family G member 2transporter
CannabidiolEquilibrative nucleoside transporter 1transporter
CannabidiolTransient receptor potential cation channel subfamily V member 1target
CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Htarget
CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Itarget
CannabidiolTransient receptor potential cation channel subfamily A member 1target
CannabidiolTransient receptor potential cation channel subfamily M member 8target
CannabidiolTransient receptor potential cation channel subfamily V member 2target
CannabidiolTransient receptor potential cation channel subfamily V member 3target
CannabidiolTransient receptor potential cation channel subfamily V member 4target
CannabidiolVoltage-dependent anion-selective channel protein 1target
Cannabidiol5-hydroxytryptamine receptor 3Atarget
CannabidiolAdenosine receptor A1target
CannabidiolProstaglandin G/H synthase 1target
CannabidiolProstaglandin G/H synthase 2target
CannabidiolAcetyl-CoA acetyltransferase, mitochondrialtarget
CannabidiolSteroid 17-alpha-hydroxylase/17,20 lyasetarget
Cannabidiol3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
CannabidiolGlutathione reductase, mitochondrialtarget
CannabidiolGlutathione peroxidase 1target
CannabidiolIndoleamine 2,3-dioxygenase 1target
CannabidiolCytochrome P450 1B1target
CannabidiolNAD(P)H dehydrogenase [quinone] 1target
CannabidiolCatalasetarget
CannabidiolCytochrome P450 3A5target
CannabidiolCytochrome P450 2D6target
CannabidiolSuperoxide dismutase [Cu-Zn]target
CannabidiolCytochrome P450 1A2target
CannabidiolCytochrome P450 3A7target
CannabidiolArylalkylamine N-acetyltransferasetarget
CannabidiolN-acylethanolamine-hydrolyzing acid amidasetarget
Medical CannabisCannabinoid receptor 1target
Medical CannabisCannabinoid receptor 2target
Medical CannabisCytochrome P450 2C9enzyme
Medical CannabisCytochrome P450 2C19enzyme
Medical CannabisCytochrome P450 2D6enzyme
Medical CannabisCytochrome P450 3A4enzyme
Medical CannabisG-protein coupled receptor 12target
Medical CannabisGlycine receptor subunit alpha-1target
Medical CannabisGlycine receptor (alpha-1/beta)target
Medical CannabisGlycine receptor subunit alpha-3target
Medical CannabisN-arachidonyl glycine receptortarget
Medical CannabisG-protein coupled receptor 55target
Medical Cannabis5-hydroxytryptamine receptor 1Atarget
Medical Cannabis5-hydroxytryptamine receptor 2Atarget
Medical CannabisNeuronal acetylcholine receptor subunit alpha-7target
Medical CannabisDelta-type opioid receptortarget
Medical CannabisMu-type opioid receptortarget
Medical CannabisPeroxisome proliferator-activated receptor gammatarget
Medical CannabisCytochrome P450 3A5enzyme
Medical CannabisCytochrome P450 3A7enzyme
Medical CannabisCytochrome P450 1A1enzyme
Medical CannabisCytochrome P450 1A2enzyme
Medical CannabisCytochrome P450 1B1enzyme
Medical CannabisArachidonate 5-lipoxygenaseenzyme
Medical CannabisArachidonate 15-lipoxygenaseenzyme
Medical CannabisSuperoxide dismutase [Cu-Zn]enzyme
Medical CannabisMultidrug resistance-associated protein 1transporter
Medical CannabisATP-binding cassette sub-family G member 2transporter
Medical CannabisEquilibrative nucleoside transporter 1transporter
Medical CannabisTransient receptor potential cation channel subfamily V member 1target
Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Htarget
Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Itarget
Medical CannabisTransient receptor potential cation channel subfamily A member 1target
Medical CannabisTransient receptor potential cation channel subfamily M member 8target
Medical CannabisTransient receptor potential cation channel subfamily V member 2target
Medical CannabisTransient receptor potential cation channel subfamily V member 3target
Medical CannabisTransient receptor potential cation channel subfamily V member 4target
Medical CannabisVoltage-dependent anion-selective channel protein 1target
Medical CannabisN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase Dtarget
Medical CannabisN-acylethanolamine-hydrolyzing acid amidasetarget
Medical CannabisArylalkylamine N-acetyltransferasetarget
Medical CannabisPhospholipase A2target
Medical CannabisSuperoxide dismutase [Cu-Zn]target
Medical CannabisFatty-acid amide hydrolase 1target
Medical CannabisCatalasetarget
Medical CannabisQuinone oxidoreductasetarget
Medical CannabisSphingomyelin phosphodiesterasetarget
Medical CannabisGlutathione peroxidase 1target
Medical CannabisGlutathione reductase, mitochondrialtarget
Medical Cannabis3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
Medical CannabisIndoleamine 2,3-dioxygenase 1target
Medical CannabisProstaglandin G/H synthase 1target
Medical CannabisProstaglandin G/H synthase 2target
Medical CannabisSteroid 17-alpha-hydroxylase/17,20 lyasetarget
Medical CannabisAcetyl-CoA acetyltransferase, mitochondrialtarget
NabiximolsCannabinoid receptor 1target
NabiximolsCannabinoid receptor 2target
NabiximolsG-protein coupled receptor 12target
NabiximolsCytochrome P450 2C9enzyme
NabiximolsCytochrome P450 2C19enzyme
NabiximolsCytochrome P450 2D6enzyme
NabiximolsCytochrome P450 3A4enzyme
NabiximolsGlycine receptor subunit alpha-1target
NabiximolsGlycine receptor (alpha-1/beta)target
NabiximolsGlycine receptor subunit alpha-3target
NabiximolsN-arachidonyl glycine receptortarget
NabiximolsG-protein coupled receptor 55target
Nabiximols5-hydroxytryptamine receptor 1Atarget
Nabiximols5-hydroxytryptamine receptor 2Atarget
NabiximolsNeuronal acetylcholine receptor subunit alpha-7target
NabiximolsDelta-type opioid receptortarget
NabiximolsMu-type opioid receptortarget
NabiximolsPeroxisome proliferator-activated receptor gammatarget
NabiximolsCytochrome P450 3A5enzyme
NabiximolsArachidonate 5-lipoxygenaseenzyme
NabiximolsArachidonate 15-lipoxygenaseenzyme
NabiximolsMultidrug resistance-associated protein 1transporter
NabiximolsATP-binding cassette sub-family G member 2transporter
NabiximolsEquilibrative nucleoside transporter 1transporter
NabiximolsTransient receptor potential cation channel subfamily V member 1target
NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Itarget
NabiximolsTransient receptor potential cation channel subfamily A member 1target
NabiximolsTransient receptor potential cation channel subfamily M member 8target
NabiximolsTransient receptor potential cation channel subfamily V member 2target
NabiximolsTransient receptor potential cation channel subfamily V member 3target
NabiximolsTransient receptor potential cation channel subfamily V member 4target
NabiximolsVoltage-dependent anion-selective channel protein 1target
NabiximolsProstaglandin G/H synthase 1target
NabiximolsProstaglandin G/H synthase 2target
NabiximolsAcetyl-CoA acetyltransferase, mitochondrialtarget
NabiximolsSteroid 17-alpha-hydroxylase/17,20 lyasetarget
Nabiximols3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
NabiximolsGlutathione reductase, mitochondrialtarget
NabiximolsGlutathione peroxidase 1target
NabiximolsIndoleamine 2,3-dioxygenase 1target
NabiximolsArylalkylamine N-acetyltransferasetarget
NabiximolsCytochrome P450 1B1target
NabiximolsCytochrome P450 3A5target
NabiximolsCytochrome P450 2D6target
NabiximolsCytochrome P450 1A2target
NabiximolsCytochrome P450 1A1target
NabiximolsCytochrome P450 3A7target
NabiximolsQuinone oxidoreductasetarget
NabiximolsCatalasetarget
NabiximolsFatty-acid amide hydrolase 1target
NabiximolsSuperoxide dismutase [Cu-Zn]target
NabiximolsN-acylethanolamine-hydrolyzing acid amidasetarget
Curcumin sulfatePeroxisome proliferator-activated receptor gammatarget
Curcumin sulfateVitamin D3 receptortarget
Curcumin sulfateMultidrug resistance-associated protein 5target
Curcumin sulfateCarbonyl reductase [NADPH] 1target
Curcumin sulfateGlutathione S-transferase Ptarget
Curcumin sulfateCytochrome P450 2C9enzyme
Curcumin sulfateCytochrome P450 2B6enzyme
Curcumin sulfateCytochrome P450 1A2enzyme
Curcumin sulfateCytochrome P450 2D6enzyme
Curcumin sulfateP-glycoprotein 1transporter
Curcumin sulfateCytochrome P450 3A4enzyme
Curcumin sulfateCytochrome P450 3A5enzyme
Curcumin sulfateUDP-glucuronosyltransferases (UGTs)enzyme
Curcumin sulfateCytochrome P450 2C19enzyme
Curcumin sulfateSulfotransferase 1A3/1A4enzyme
Curcumin sulfateSulfotransferase family cytosolic 1B member 1enzyme
Curcumin sulfateEstrogen sulfotransferaseenzyme
Curcumin sulfateSulfotransferase 1C4enzyme
OxcarbazepineCytochrome P450 2C19enzyme
OxcarbazepineCytochrome P450 3A4enzyme
OxcarbazepineCytochrome P450 3A5enzyme
OxcarbazepineSerum albumincarrier
OxcarbazepineP-glycoprotein 1transporter
OxcarbazepineAldo-keto reductase family 1 member C1enzyme
OxcarbazepineAldo-keto reductase family 1 member C2enzyme
OxcarbazepineAldo-keto reductase family 1 member C3enzyme
OxcarbazepineAldo-keto reductase family 1 member C4enzyme
OxcarbazepineCarbonyl reductase [NADPH] 1enzyme
OxcarbazepineCarbonyl reductase [NADPH] 3enzyme
OxcarbazepineSodium channel proteintarget
DronedaroneAlpha-1A adrenergic receptortarget
DronedaroneBeta-1 adrenergic receptortarget
DronedaroneAlpha-1B adrenergic receptortarget
DronedaroneAlpha-1D adrenergic receptortarget
DronedaroneAlpha-2A adrenergic receptortarget
DronedaroneAlpha-2B adrenergic receptortarget
DronedaroneAlpha-2C adrenergic receptortarget
DronedaronePotassium voltage-gated channel subfamily H member 2target
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Starget
DronedaroneVoltage-dependent L-type calcium channel subunit beta-1target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-2target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-3target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-4target
DronedaroneCytochrome P450 2D6enzyme
DronedaroneCytochrome P450 3A4enzyme
DronedaroneP-glycoprotein 1transporter
DronedaronePotassium channel subfamily K member 2target
DronedaroneSerum albumincarrier
DronedaroneSolute carrier family 22 member 2transporter
DronedaroneSolute carrier family 22 member 1transporter
DronedaroneSolute carrier organic anion transporter family member 1B1transporter
DronedaroneSolute carrier organic anion transporter family member 1B3transporter
DronedaroneSolute carrier family 22 member 8transporter
DronedaroneCytochrome P450 3A5enzyme
DronedaroneCytochrome P450 2J2enzyme
DronedaroneThyroid hormone receptor alphatarget
DronedaroneSodium channel protein type 5 subunit alphatarget
DronedaroneG protein-activated inward rectifier potassium channel 1target
DronedaronePotassium voltage-gated channel subfamily KQT member 1target
DronedaroneInward rectifier potassium channeltarget
DronedaroneSodium/calcium exchanger 1target
DronedaronePotassium voltage-gated channel subfamily D member 3target
CenobamateUDP-glucuronosyltransferase 2B7enzyme
CenobamateUDP-glucuronosyltransferase 2B4enzyme
CenobamateCytochrome P450 2E1enzyme
CenobamateCytochrome P450 2A6enzyme
CenobamateCytochrome P450 2B6enzyme
CenobamateCytochrome P450 2C19enzyme
CenobamateCytochrome P450 3A4enzyme
CenobamateCytochrome P450 3A5enzyme
CenobamateSerum albumincarrier
CenobamateCytochrome P450 2C8enzyme
Methylene blueGuanylate cyclase soluble subunit alpha-2target
Methylene blueNitric oxide synthase, braintarget
Methylene blueUDP-glucuronosyltransferase 1-4enzyme
Methylene blueUDP-glucuronosyltransferase 1-9enzyme
Methylene blueCytochrome P450 1A2enzyme
Methylene blueCytochrome P450 2B6enzyme
Methylene blueCytochrome P450 2C8enzyme
Methylene blueCytochrome P450 2C9enzyme
Methylene blueCytochrome P450 2C19enzyme
Methylene blueCytochrome P450 3A4enzyme
Methylene blueCytochrome P450 3A5enzyme
Methylene blueSerum albumincarrier
Methylene blueP-glycoprotein 1transporter
Methylene blueSolute carrier family 22 member 2transporter
Methylene blueMultidrug and toxin extrusion protein 2transporter
Methylene blueMultidrug and toxin extrusion protein 1transporter
Methylene blueFlavin reductase (NADPH)enzyme
Methylene blueCytochrome P450 2D6enzyme
ClofazimineCytochrome P450 3A4enzyme
ClofaziminePeroxisome proliferator-activated receptor gammatarget
ClofazimineCytochrome P450 2C8enzyme
ClofazimineCytochrome P450 2D6enzyme
ClofazimineCytochrome P450 3A5enzyme
ClofaziminePotassium voltage-gated channel subfamily A member 3target
ClofazimineSerum albumincarrier
ClofazimineP-glycoprotein 1transporter
ClofazimineATP-binding cassette sub-family G member 2transporter
ClofazimineMultidrug resistance-associated protein 1transporter
PralsetinibProto-oncogene tyrosine-protein kinase receptor Rettarget
PralsetinibEpithelial discoidin domain-containing receptor 1target
PralsetinibNT-3 growth factor receptortarget
PralsetinibReceptor-type tyrosine-protein kinase FLT3target
PralsetinibTyrosine-protein kinase JAK1target
PralsetinibTyrosine-protein kinase JAK2target
PralsetinibHigh affinity nerve growth factor receptortarget
PralsetinibVascular endothelial growth factor receptor 2target
PralsetinibPlatelet-derived growth factor receptor betatarget
PralsetinibFibroblast growth factor receptor 1target
PralsetinibFibroblast growth factor receptor 2target
PralsetinibCytochrome P450 3A4enzyme
PralsetinibCytochrome P450 3A5enzyme
PralsetinibCytochrome P450 2D6enzyme
PralsetinibCytochrome P450 1A2enzyme
PralsetinibCytochrome P450 2C8enzyme
PralsetinibCytochrome P450 2C9enzyme
PralsetinibP-glycoprotein 1transporter
PralsetinibATP-binding cassette sub-family G member 2transporter
PralsetinibSolute carrier organic anion transporter family member 1B1transporter
PralsetinibSolute carrier organic anion transporter family member 1B3transporter
PralsetinibSolute carrier family 22 member 6transporter
PralsetinibMultidrug and toxin extrusion protein 1transporter
PralsetinibMultidrug and toxin extrusion protein 2transporter
PralsetinibBile salt export pumptransporter