ErbB Receptors, antagonists & inhibitors

Name
ErbB Receptors, antagonists & inhibitors
Accession Number
DBCAT005008
Description

Not Available

Drugs
DrugDrug Description
PelitinibInvestigated for use/treatment in colorectal cancer and lung cancer.
AV-412Investigated for use/treatment in cancer/tumors (unspecified).
NecitumumabA monoclonal antibody used to treat metastatic squamous non-small cell lung cancer.
TesevatinibTesevatinib has been used in trials studying the treatment of Cancer, Stomach Cancer, Brain Metastases, Esophageal Cancer, and Leptomeningeal Metastases, among others. Tesevatinib is a potent inhibitor of multiple RTKs...
BMS-599626BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.
AEE-788AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
Drugs & Drug Targets
DrugTargetType
PelitinibEpidermal growth factor receptortarget
AV-412Epidermal growth factor receptortarget
AV-412Receptor tyrosine-protein kinase erbB-2target
NecitumumabEpidermal growth factor receptortarget
TesevatinibPro-epidermal growth factortarget
TesevatinibEphrin type-B receptor 4target
TesevatinibReceptor tyrosine-protein kinase erbB-2target