Intracellular Signaling Peptides and Proteins
- Name
- Intracellular Signaling Peptides and Proteins
- Accession Number
- DBCAT005588
- Description
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.
- Drugs
Drug Drug Description Nelipepimut-S Investigated for use/treatment in prostate cancer and breast cancer. Luspatercept An erythroid maturation agent used to treat anemia secondary to beta thalassemia, myelodysplastic syndromes, and neoplasms. Dalantercept Dalantercept is under investigation in clinical trial NCT00996957 (Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma). VEGFR2-169 VEGFR2-169 is under investigation in clinical trial NCT00655785 (Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer (Phase1/2)). CBP-501 Not Annotated Recombinant human plasma gelsolin Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues. - Drugs & Drug Targets
Drug Target Type Nelipepimut-S HLA class I histocompatibility antigen, A-2 alpha chain target Nelipepimut-S HLA class I histocompatibility antigen, A-3 alpha chain target