Adrenergic beta-1 Receptor Antagonists

Name
Adrenergic beta-1 Receptor Antagonists
Accession Number
DBCAT000458
Description

Drugs that bind to and block the activation of ADRENERGIC BETA-1 RECEPTORS.

Drugs
DrugDrug Description
AcebutololA selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
AtenololA synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
BetaxololA cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
BevantololFor the treatment of angina pectoris and hypertension.
BisoprololA beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension.
CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
CeliprololA beta-blocker for the management of hypertension and angina pectoris.
EsmololA cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension.
MetoprololA beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction.
PractololUsed in the emergency treatment of cardiac arrhythmias.
Drugs & Drug Targets
DrugTargetType
AcebutololATP-dependent translocase ABCB1transporter
AcebutololBeta-2 adrenergic receptortarget
AcebutololCytochrome P450 2D6enzyme
AcebutololBeta-1 adrenergic receptortarget
AtenololBeta-1 adrenergic receptortarget
AtenololBeta-2 adrenergic receptortarget
AtenololCytochrome P450 2D6enzyme
AtenololBile salt export pumptransporter
AtenololAlbumincarrier
BetaxololBeta-1 adrenergic receptortarget
BetaxololBeta-2 adrenergic receptortarget
BetaxololCytochrome P450 1A2enzyme
BetaxololCytochrome P450 2D6enzyme
BevantololBeta-1 adrenergic receptortarget
BevantololD(2) dopamine receptortarget
BevantololCytochrome P450 2D6enzyme
BevantololAlpha-1A adrenergic receptortarget
BevantololBeta-2 adrenergic receptortarget
BisoprololATP-dependent translocase ABCB1transporter
BisoprololBeta-1 adrenergic receptortarget
BisoprololBeta-2 adrenergic receptortarget
BisoprololCytochrome P450 3A4enzyme
CarvedilolE-selectintarget
CarvedilolHypoxia-inducible factor 1-alphatarget
CarvedilolInward rectifier potassium channel 4target
CarvedilolUDP-glucuronosyltransferase 1A1enzyme
CarvedilolAlbumincarrier
CarvedilolAlpha-1 adrenergic receptorstarget
CarvedilolUDP-glucuronosyltransferase 2B4enzyme
CarvedilolUDP-glucuronosyltransferase 2B7enzyme
CarvedilolInward rectifier potassium channel 2target
CarvedilolBeta adrenergic receptortarget
CarvedilolAlpha-2A adrenergic receptortarget
CarvedilolAlpha-2B adrenergic receptortarget
CarvedilolAlpha-2C adrenergic receptortarget
CarvedilolAlpha-1B adrenergic receptortarget
CarvedilolAlpha-1D adrenergic receptortarget
CarvedilolCytochrome P450 2E1enzyme
CarvedilolCytochrome P450 1A1enzyme
CarvedilolCytochrome P450 3A4enzyme
CarvedilolCytochrome P450 1A2enzyme
CarvedilolATP-dependent translocase ABCB1transporter
CarvedilolAlpha-1A adrenergic receptortarget
CarvedilolBeta-1 adrenergic receptortarget
CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
CarvedilolBeta-2 adrenergic receptortarget
CarvedilolVascular endothelial growth factor A, long formtarget
CarvedilolNatriuretic peptides Btarget
CarvedilolGap junction alpha-1 proteintarget
CarvedilolVoltage-gated inwardly rectifying potassium channel KCNH2target
CarvedilolVascular cell adhesion protein 1target
CarvedilolCytochrome P450 2C9enzyme
CarvedilolCytochrome P450 2D6enzyme
CarvedilolXanthine dehydrogenase/oxidaseenzyme
CeliprololAlpha-2 adrenergic receptorstarget
CeliprololCytochrome P450 2D6enzyme
CeliprololAlpha-2C adrenergic receptortarget
CeliprololAlpha-2B adrenergic receptortarget
CeliprololAlpha-2A adrenergic receptortarget
CeliprololBeta-3 adrenergic receptortarget
CeliprololBeta-2 adrenergic receptortarget
CeliprololBeta-1 adrenergic receptortarget
EsmololBeta-2 adrenergic receptortarget
EsmololCytochrome P450 2D6enzyme
EsmololBeta-1 adrenergic receptortarget
MetoprololBeta adrenergic receptortarget
MetoprololCytochrome P450 3A4enzyme
MetoprololAlbumincarrier
MetoprololSolute carrier family 22 member 2transporter
MetoprololBeta-2 adrenergic receptortarget
MetoprololCytochrome P450 2D6enzyme
MetoprololBeta-1 adrenergic receptortarget
PractololCytochrome P450 2D6enzyme
PractololBeta-1 adrenergic receptortarget