Free Radical Scavengers

All categories

Name: Free Radical Scavengers
Accession Number: DBCAT000864
Description: Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.
Drugs: Drug Drug Description
3-hydroxyanthranilic acid An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Acetylcysteine A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.
Acetylcysteine zinc Not Available
Allicin Allicin has been used in trials studying the treatment of Follicular Lymphoma.
Allopurinol A xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
Anisodamine Anisodamine has been investigated for the treatment of Intestinal Diseases.
Avasopasem manganese Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis. This drug has potential...
Bisphenol A Not Available
Dimethyl sulfoxide A reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer.
Edaravone A free radical scavenger used to delay the progression of ALS.
Ferulic acid Not Available
Honokiol Honokiol is under investigation in clinical trial NCT00966953 (Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.).
Nitric Oxide A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
p-Coumaric acid Not Available
Pentoxifylline A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
Tetradecylthioacetic acid Not Available
Drugs & Drug Targets: Drug Target Type
3-hydroxyanthranilic acid Trans-2,3-dihydro-3-hydroxyanthranilate isomerase target
Acetylcysteine Cystine/glutamate transporter target
Acetylcysteine Aminoacylase-1 enzyme
Acetylcysteine Albumin carrier
Acetylcysteine Glutamate receptor ionotropic, NMDA 3A target
Acetylcysteine Glutamate receptor ionotropic, NMDA 2D target
Acetylcysteine Glutamate receptor ionotropic, NMDA 2A target
Acetylcysteine Glutamate receptor ionotropic, NMDA 1 target
Acetylcysteine Glutamate receptor ionotropic, NMDA 2B target
Acetylcysteine Glutathione synthetase target
Acetylcysteine Inhibitor of nuclear factor kappa-B kinase subunit beta target
Acetylcysteine Inhibitor of nuclear factor kappa-B kinase subunit alpha target
Acetylcysteine Aminoacylase-1 target
Acetylcysteine Solute carrier family 22 member 6 transporter
Acetylcysteine NAPQI (N-acetyl-p-benzoquinone imine) target
Acetylcysteine Solute carrier organic anion transporter family member 1B1 transporter
Allicin Transient receptor potential cation channel subfamily A member 1 target
Allicin Transient receptor potential cation channel subfamily V member 1 target
Allicin ATP-dependent translocase ABCB1 transporter
Allicin Cytochrome P450 3A4 enzyme
Allicin Acetylcholinesterase target
Allicin Cholinesterase target
Allopurinol Xanthine dehydrogenase/oxidase target
Allopurinol Organic anion transporter 3 transporter
Allopurinol Solute carrier family 22 member 7 transporter
Allopurinol Aldehyde oxidase enzyme
Allopurinol Xanthine dehydrogenase/oxidase enzyme
Allopurinol Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Allopurinol Solute carrier family 22 member 2 transporter
Allopurinol Cytochrome P450 1A2 enzyme
Anisodamine Cytochrome P450 2D6 enzyme
Anisodamine Beta-1 adrenergic receptor target
Avasopasem manganese Superoxide dismutase target
Bisphenol A Estrogen receptor beta target
Bisphenol A Androgen receptor target
Bisphenol A Estrogen-related receptor gamma target
Dimethyl sulfoxide Myc proto-oncogene protein target
Dimethyl sulfoxide Interleukin-5 receptor subunit alpha target
Dimethyl sulfoxide Mucin-16 target
Dimethyl sulfoxide Cytochrome P450 3A4 enzyme
Dimethyl sulfoxide Cytochrome P450 2D6 enzyme
Dimethyl sulfoxide Cytochrome P450 2C19 enzyme
Dimethyl sulfoxide Transthyretin carrier
Edaravone UDP-glucuronosyltransferase 2B17 enzyme
Edaravone UDP-glucuronosyltransferase 1A6 enzyme
Edaravone UDP-glucuronosyltransferase 1A7 enzyme
Edaravone UDP-glucuronosyltransferase 1A8 enzyme
Edaravone UDP-glucuronosyltransferase 1A9 enzyme
Edaravone UDP-glucuronosyltransferase 1A10 enzyme
Edaravone UDP-glucuronosyltransferase 2B7 enzyme
Edaravone Sulfotransferase enzyme
Edaravone Albumin carrier
Edaravone Apoptosis regulator Bcl-2 target
Edaravone UDP-glucuronosyltransferase 1A1 enzyme
Edaravone Organic anion transporter 3 transporter
Edaravone Solute carrier family 22 member 6 transporter
Ferulic acid Carbonic anhydrase 4 target
Ferulic acid Carbonic anhydrase 1 target
Ferulic acid Amine oxidase [flavin-containing] B target
Ferulic acid Endo-1,4-beta-xylanase Y target
Ferulic acid Endo-1,4-beta-xylanase Z target
Ferulic acid Est1e target
Ferulic acid O-methyltransferase target
Ferulic acid Monocarboxylate transporter 1 transporter
Ferulic acid Monocarboxylate transporter 4 transporter
Ferulic acid Carbonic anhydrase 12 target
Ferulic acid Carbonic anhydrase 2 target
Ferulic acid Carbonic anhydrase 14 target
Ferulic acid Carbonic anhydrase 9 target
Ferulic acid Carbonic anhydrase 6 target
Honokiol Prostaglandin G/H synthase 2 target
Honokiol Prostaglandin G/H synthase 1 target
Honokiol Polyunsaturated fatty acid 5-lipoxygenase target
Nitric Oxide Guanylate cyclase soluble subunit alpha-2 target
Nitric Oxide Aldehyde dehydrogenase, mitochondrial enzyme
Nitric Oxide Cytochrome P450 1A2 enzyme
Nitric Oxide Cytochrome P450 2B6 enzyme
Nitric Oxide Cytochrome P450 3A4 enzyme
Nitric Oxide Metallothionein-1A target
Nitric Oxide Indoleamine 2,3-dioxygenase 1 target
Nitric Oxide Nitric oxide synthase 3 target
Nitric Oxide Guanylate cyclase soluble subunit alpha-1 target
Nitric Oxide Guanylate cyclase soluble subunit beta-1 target
p-Coumaric acid Carbonic anhydrase 4 target
p-Coumaric acid Photoactive yellow protein target
p-Coumaric acid Photoactive yellow protein target
p-Coumaric acid Prostaglandin reductase 1 target
p-Coumaric acid Tyrosine ammonia-lyase target
p-Coumaric acid Carbonic anhydrase 12 target
p-Coumaric acid Carbonic anhydrase 2 target
p-Coumaric acid Carbonic anhydrase 14 target
p-Coumaric acid Carbonic anhydrase 9 target
p-Coumaric acid Carbonic anhydrase 6 target
p-Coumaric acid Carbonic anhydrase 1 target
Pentoxifylline Phosphodiesterase enzymes target
Pentoxifylline Cytochrome P450 1A2 enzyme
Pentoxifylline Adenosine receptor A2a target
Pentoxifylline Tumor necrosis factor target
Pentoxifylline 5'-nucleotidase target
Pentoxifylline Cyclic nucleotide phosphodiesterase target
Pentoxifylline Adenosine receptor A1 target
Tetradecylthioacetic acid Peroxisome proliferator-activated receptor alpha target
Tetradecylthioacetic acid Peroxisome proliferator-activated receptor gamma target

Drug	Drug Description
3-hydroxyanthranilic acid	An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Acetylcysteine	A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.
Acetylcysteine zinc	Not Available
Allicin	Allicin has been used in trials studying the treatment of Follicular Lymphoma.
Allopurinol	A xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
Anisodamine	Anisodamine has been investigated for the treatment of Intestinal Diseases.
Avasopasem manganese	Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis. This drug has potential...
Bisphenol A	Not Available
Dimethyl sulfoxide	A reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer.
Edaravone	A free radical scavenger used to delay the progression of ALS.
Ferulic acid	Not Available
Honokiol	Honokiol is under investigation in clinical trial NCT00966953 (Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.).
Nitric Oxide	A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
p-Coumaric acid	Not Available
Pentoxifylline	A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
Tetradecylthioacetic acid	Not Available

Free Radical Scavengers

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