Reverse Transcriptase Inhibitors
- Name
- Reverse Transcriptase Inhibitors
- Accession Number
- DBCAT000594
- Description
Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
- Drugs
Drug Drug Description Abacavir An antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. Adefovir Not Annotated Adefovir dipivoxil A nucleotide analog used to treat chronic hepatitis B. Ammonium trichlorotellurate Ammonium trichlorotellurate is an investigational compound with anti-tumour and anti-inflammatory properties. Arsanilic acid An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem] Atevirdine Atevirdine has been used in trials studying the treatment of HIV Infections. Capravirine Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection. Censavudine Censavudine has been used in trials studying the treatment of HIV-1 Infection. Delavirdine A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. Dexelvucitabine Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus. Didanosine A reverse transcriptase inhibitor used to treat HIV. Efavirenz A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. Elvucitabine Investigated for use/treatment in hepatitis (viral, B) and HIV infection. Emivirine Emivirine has been used in trials studying the treatment of HIV Infections. Emtricitabine A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. Etravirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. Foscarnet An antiviral used to treat CMV, HIV, and HSV infections. Islatravir A nucleoside analog reverse transcriptase inhibitor (NRTI) indicated in combination with doravirine for the treatment of HIV-1 infection in virologically-suppressed adults on a stable antiretroviral regimen. Lamivudine A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. Lapachone Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell. Lobucavir Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections. Nevirapine A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. Oltipraz Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease. Penciclovir A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. Phosphonoacetic Acid A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem] R-82913 Not Available Rilpivirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). Rovafovir etalafenamide Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen). Stavudine A dideoxynucleoside used in the treatment of HIV infection. Tenofovir A nucleotide analog indicated in the treatment of HIV infections. Tenofovir disoproxil A nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection. Ulonivirine Not Available Zalcitabine A dideoxynucleoside used to treat HIV. Zidovudine A dideoxynucleoside used in the treatment of HIV infection. - Drugs & Drug Targets