Adefovir

DB13868InvestigationalSmall moleculeHepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor

Adefovir: Overview.

Chemical structure of Adefovir
Mechanism
Curator reviewed
Formula / weight
C8H12N5O4P · 273.1857 g/mol (avg)
Code names
GS-0393

Resolves to

Compound
UNII6GQP90I798CAS106941-25-7ChEMBLCHEMBL484ChEBI2469
Clinical / RWD
RxNorm16521
Structure
InChIKeySUPKOOSCJHTBAH-UHFFFAOYSA-NSMILESNC1=C2N=CN(CCOCP(O)(O)=O)C2=NC=N1
Targets
P24024PP04293DNA polymerase catalytic subunit

What you can answer from here — as of April 23, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
704Drug interactionsStructured to mechanism, not free text
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28Clinical trialsPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Adefovir, and which of those have an active Phase 3 trial?

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